Page last updated: 2024-10-19

phosphorylcholine and Bleeding

phosphorylcholine has been researched along with Bleeding in 10 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Research Excerpts

ExcerptRelevanceReference
"Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in atherosclerosis, due to its atherogenic and proinflammatory effects."8.12Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts. ( Baganha, F; de Jong, RCM; de Vries, MR; Delibegovic, M; Jukema, JW; Peters, HAB; Pettersson, K; Quax, PHA; Sluiter, TJ; van Alst, LA, 2022)
"Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in atherosclerosis, due to its atherogenic and proinflammatory effects."4.12Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts. ( Baganha, F; de Jong, RCM; de Vries, MR; Delibegovic, M; Jukema, JW; Peters, HAB; Pettersson, K; Quax, PHA; Sluiter, TJ; van Alst, LA, 2022)
"Pulmonary hemorrhage was present in 55% of 159 infants undergoing autopsy; the incidence was not different in infants treated with surfactant or air placebo."2.67Pulmonary hemorrhage in premature infants after treatment with synthetic surfactant: an autopsy evaluation. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group. ( Derleth, D; Finer, N; Long, W; McMurray, B; Mullett, M; Peliowski, A; Sankaran, K; van Houten, J; Walker, D; Wold, D, 1992)
"Pre-treatment with mecamylamine (50 mug; i."1.35Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations. ( Cansev, M; Hamurtekin, E; Ilcol, YO; Ulus, IH; Yilmaz, MS, 2008)
"Pulmonary hemorrhage was defined by an onset of bright red blood from the endotracheal tube in quantities that resulted in increased ventilatory support and a new infiltrate on a chest radiograph."1.29Pulmonary hemorrhage risk in infants with a clinically diagnosed patent ductus arteriosus: a retrospective cohort study. ( Buck, R; Garland, J; Weinberg, M, 1994)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Baganha, F1
Sluiter, TJ1
de Jong, RCM1
van Alst, LA1
Peters, HAB1
Jukema, JW1
Delibegovic, M1
Pettersson, K1
Quax, PHA1
de Vries, MR1
Marguerite, S1
Levy, F1
Quessard, A1
Dupeyron, JP1
Gros, C1
Steib, A1
Agarwal, PK1
Cansev, M1
Ilcol, YO1
Yilmaz, MS1
Hamurtekin, E1
Ulus, IH1
Findlay, RD1
Taeusch, HW1
David-Cu, R1
Walther, FJ1
Garland, J1
Buck, R1
Weinberg, M1
Majeed-Saidan, MA1
al-Hifzi, I1
Khan, M1
Rogers, D1
Bhatt-Mehta, V1
Schumacher, RE1
van Houten, J1
Long, W1
Mullett, M1
Finer, N1
Derleth, D1
McMurray, B1
Peliowski, A1
Walker, D1
Wold, D1
Sankaran, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Two Different Natural Surfactants in the Treatment of Pulmonary Hemorrhage[NCT01860014]20 participants (Actual)Interventional2010-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for phosphorylcholine and Bleeding

ArticleYear
Impact of a phosphorylcholine-coated cardiac bypass circuit on blood loss and platelet function: a prospective, randomized study.
    The journal of extra-corporeal technology, 2012, Volume: 44, Issue:1

    Topics: Aged; Cardiopulmonary Bypass; Coated Materials, Biocompatible; Hemorrhage; Humans; Male; Middle Aged

2012
Pulmonary hemorrhage in premature infants after treatment with synthetic surfactant: an autopsy evaluation. The American Exosurf Neonatal Study Group I, and the Canadian Exosurf Neonatal Study Group.
    The Journal of pediatrics, 1992, Volume: 120, Issue:2 Pt 2

    Topics: Autopsy; Double-Blind Method; Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Incidence; Infa

1992

Other Studies

8 other studies available for phosphorylcholine and Bleeding

ArticleYear
Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts.
    International journal of molecular sciences, 2022, Nov-07, Volume: 23, Issue:21

    Topics: Animals; Antibodies, Monoclonal; Atherosclerosis; Hemorrhage; Humans; Male; Mice; Neovascularization

2022
Miltefosine for Indian visceral leishmaniasis.
    The New England journal of medicine, 2003, Feb-27, Volume: 348, Issue:9

    Topics: Antiprotozoal Agents; Hemorrhage; HIV Infections; Humans; Leishmaniasis, Visceral; Phosphorylcholine

2003
Peripheral administration of CDP-choline, phosphocholine or choline increases plasma adrenaline and noradrenaline concentrations.
    Autonomic & autacoid pharmacology, 2008, Volume: 28, Issue:1

    Topics: Adrenal Glands; Animals; Atropine Derivatives; Autonomic Nervous System; Central Nervous System; Cho

2008
Lysis of red blood cells and alveolar epithelial toxicity by therapeutic pulmonary surfactants.
    Pediatric research, 1995, Volume: 37, Issue:1

    Topics: Animals; Biological Products; Drug Combinations; Epithelial Cells; Epithelium; Fatty Alcohols; Hemol

1995
Pulmonary hemorrhage risk in infants with a clinically diagnosed patent ductus arteriosus: a retrospective cohort study.
    Pediatrics, 1994, Volume: 94, Issue:5

    Topics: Cohort Studies; Drug Combinations; Ductus Arteriosus, Patent; Fatty Alcohols; Female; Hemorrhage; Hu

1994
Pulmonary haemorrhage in low-birthweight babies.
    Lancet (London, England), 1993, Jan-09, Volume: 341, Issue:8837

    Topics: Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Hyaline Membrane Disease; Infant, Low Birth W

1993
Pulmonary haemorrhage, surfactant, and low-birthweight babies.
    Lancet (London, England), 1993, Mar-13, Volume: 341, Issue:8846

    Topics: Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Infant, Low Birth Weight; Infant, Newborn; Lu

1993
Criteria for use of colfosceril (Exosurf) in neonates.
    Clinical pharmacy, 1992, Volume: 11, Issue:4

    Topics: Apnea; Drug Combinations; Fatty Alcohols; Hemorrhage; Humans; Infant, Newborn; Intubation, Intratrac

1992