phosphorylcholine has been researched along with Bipolar Disorder in 5 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As choline is a marker of membrane phospholipid metabolism, the elevated choline in patients may indicate increased membrane breakdown in the brain regions examined." | 5.35 | Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study. ( Hall, GB; MacQueen, GM; Milne, AM; Senaratne, R, 2009) |
| "The few studies applying single-voxel ¹H spectroscopy in children and adolescents with bipolar disorder (BD) have reported low N-acetyl-aspartate (NAA) levels in the dorsolateral prefrontal cortex (DLPFC), and high myo-inositol / phosphocreatine plus creatine (PCr+Cr) ratios in the anterior cingulate." | 3.77 | Lower N-acetyl-aspartate levels in prefrontal cortices in pediatric bipolar disorder: a ¹H magnetic resonance spectroscopy study. ( Caetano, SC; Chen, HH; Fonseca, M; Hatch, JP; Hunter, K; Lafer, B; Nicoletti, M; Olvera, RL; Pliszka, SR; Sanches, M; Soares, JC; Stanley, JA, 2011) |
| "As choline is a marker of membrane phospholipid metabolism, the elevated choline in patients may indicate increased membrane breakdown in the brain regions examined." | 1.35 | Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study. ( Hall, GB; MacQueen, GM; Milne, AM; Senaratne, R, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, B | 1 |
| Stanley, JA | 3 |
| Passos, IC | 1 |
| Mwangi, B | 1 |
| Selvaraj, S | 1 |
| Zunta-Soares, GB | 1 |
| Soares, JC | 3 |
| Senaratne, R | 1 |
| Milne, AM | 1 |
| MacQueen, GM | 1 |
| Hall, GB | 1 |
| Caetano, SC | 2 |
| Olvera, RL | 2 |
| Hatch, JP | 2 |
| Sanches, M | 1 |
| Chen, HH | 2 |
| Nicoletti, M | 2 |
| Fonseca, M | 2 |
| Hunter, K | 2 |
| Lafer, B | 1 |
| Pliszka, SR | 2 |
| Silverstone, PH | 1 |
| Asghar, SJ | 1 |
| O'Donnell, T | 1 |
| Ulrich, M | 1 |
| Hanstock, CC | 1 |
1 review available for phosphorylcholine and Bipolar Disorder
| Article | Year |
|---|---|
Lithium and valproate protect against dextro-amphetamine induced brain choline concentration changes in bipolar disorder patients.
Topics: Antipsychotic Agents; Bipolar Disorder; Brain; Choline; Creatine; Dextroamphetamine; Female; Humans; | 2004 |
4 other studies available for phosphorylcholine and Bipolar Disorder
| Article | Year |
|---|---|
Elevated Choline-Containing Compound Levels in Rapid Cycling Bipolar Disorder.
Topics: Adolescent; Adult; Aged; Bipolar Disorder; Brain; Female; Glycerylphosphorylcholine; Humans; Linear | 2017 |
Increased choline-containing compounds in the orbitofrontal cortex and hippocampus in euthymic patients with bipolar disorder: a proton magnetic resonance spectroscopy study.
Topics: Adult; Analysis of Variance; Aspartic Acid; Bipolar Disorder; Case-Control Studies; Choline; Female; | 2009 |
Lower N-acetyl-aspartate levels in prefrontal cortices in pediatric bipolar disorder: a ¹H magnetic resonance spectroscopy study.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Brain Chemistry; Child; Diagnostic and Statistical Manu | 2011 |
Low levels of N-acetyl aspartate in the left dorsolateral prefrontal cortex of pediatric bipolar patients.
Topics: Adolescent; Aspartic Acid; Bipolar Disorder; Child; Creatine; Female; Glycerylphosphorylcholine; Hum | 2007 |