Page last updated: 2024-10-19

phosphorylcholine and Atheroma

phosphorylcholine has been researched along with Atheroma in 7 studies

Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.

Research Excerpts

ExcerptRelevanceReference
"Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in atherosclerosis, due to its atherogenic and proinflammatory effects."8.12Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts. ( Baganha, F; de Jong, RCM; de Vries, MR; Delibegovic, M; Jukema, JW; Peters, HAB; Pettersson, K; Quax, PHA; Sluiter, TJ; van Alst, LA, 2022)
"Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased incidence of adverse events in coronary artery disease (CAD)."7.81Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease. ( Akhavanpoor, M; Buss, SJ; Conradson, G; Doesch, AO; Domschke, G; Erbel, C; Gitsioudis, G; Gleissner, CA; Haeussler, J; Hofmann, NP; Katus, HA; Korosoglou, G; Linden, F, 2015)
"Phosphorylcholine (PC) is one of the main oxLDL epitopes playing a central role in atherosclerosis, due to its atherogenic and proinflammatory effects."4.12Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts. ( Baganha, F; de Jong, RCM; de Vries, MR; Delibegovic, M; Jukema, JW; Peters, HAB; Pettersson, K; Quax, PHA; Sluiter, TJ; van Alst, LA, 2022)
"IgM antibodies against phosphorylcholine (anti-PC) are negatively associated with atherosclerosis, cardiovascular disease (CVD) and systemic lupus erythematosus (SLE), where the risk of CVD and atherosclerosis is high."3.88IgM antibodies against phosphorylcholine promote polarization of T regulatory cells from patients with atherosclerotic plaques, systemic lupus erythematosus and healthy donors. ( Ajeganova, S; Frostegård, J; Gillgren, P; Liu, A; Lundström, SL; Rahman, M; Steuer, J; Sun, J; Zhang, B; Zubarev, RA, 2018)
"Low anti-phosphorylcholine (PC) IgM plasma levels have been associated with increased incidence of adverse events in coronary artery disease (CAD)."3.81Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease. ( Akhavanpoor, M; Buss, SJ; Conradson, G; Doesch, AO; Domschke, G; Erbel, C; Gitsioudis, G; Gleissner, CA; Haeussler, J; Hofmann, NP; Katus, HA; Korosoglou, G; Linden, F, 2015)
"Robust deposition of IgM within atherosclerotic plaques could also be readily observed in both control and experimental mice."1.43Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene. ( Binder, CJ; Centa, M; Gruber, S; Hansson, GK; Johansson, DK; Ketelhuth, DF; Malin, S; Nilsson, D; Polyzos, KA, 2016)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (85.71)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Baganha, F1
Sluiter, TJ1
de Jong, RCM1
van Alst, LA1
Peters, HAB1
Jukema, JW1
Delibegovic, M1
Pettersson, K1
Quax, PHA1
de Vries, MR1
Sun, J1
Lundström, SL1
Zhang, B1
Zubarev, RA1
Steuer, J1
Gillgren, P1
Rahman, M2
Ajeganova, S1
Liu, A2
Frostegård, J3
Grönwall, C1
Reynolds, H1
Kim, JK1
Buyon, J1
Goldberg, JD1
Clancy, RM1
Silverman, GJ1
Gleissner, CA1
Erbel, C1
Haeussler, J1
Akhavanpoor, M1
Domschke, G1
Linden, F1
Doesch, AO1
Conradson, G1
Buss, SJ1
Hofmann, NP1
Gitsioudis, G1
Katus, HA1
Korosoglou, G1
Centa, M1
Gruber, S1
Nilsson, D1
Polyzos, KA1
Johansson, DK1
Hansson, GK1
Ketelhuth, DF1
Binder, CJ1
Malin, S1
Sing, S1
Golabkesh, Z1
Fiskesund, R1
Gustafsson, T2
Jogestrand, T2
Frostegård, AG1
Hafström, I1
Anania, C1
Hua, X1
Su, J1
Vikström, M1
de Faire, U1
Heimbürger, M1

Other Studies

7 other studies available for phosphorylcholine and Atheroma

ArticleYear
Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts.
    International journal of molecular sciences, 2022, Nov-07, Volume: 23, Issue:21

    Topics: Animals; Antibodies, Monoclonal; Atherosclerosis; Hemorrhage; Humans; Male; Mice; Neovascularization

2022
IgM antibodies against phosphorylcholine promote polarization of T regulatory cells from patients with atherosclerotic plaques, systemic lupus erythematosus and healthy donors.
    Atherosclerosis, 2018, Volume: 268

    Topics: Atherosclerosis; Autoimmunity; Case-Control Studies; Cells, Cultured; Dendritic Cells; Female; Flow

2018
Relation of carotid plaque with natural IgM antibodies in patients with systemic lupus erythematosus.
    Clinical immunology (Orlando, Fla.), 2014, Volume: 153, Issue:1

    Topics: Adult; Autoantibodies; Biomarkers; Carotid Arteries; Female; Humans; Immunoglobulin M; Lupus Erythem

2014
Low levels of natural IgM antibodies against phosphorylcholine are independently associated with vascular remodeling in patients with coronary artery disease.
    Clinical research in cardiology : official journal of the German Cardiac Society, 2015, Volume: 104, Issue:1

    Topics: Aged; Autoantibodies; Biomarkers; Chi-Square Distribution; Coronary Angiography; Coronary Artery Dis

2015
Atherosclerosis Susceptibility in Mice Is Independent of the V1 Immunoglobulin Heavy Chain Gene.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:1

    Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; B-Lymphocytes; Disease Models,

2016
IgM antibodies against malondialdehyde and phosphorylcholine are together strong protection markers for atherosclerosis in systemic lupus erythematosus: Regulation and underlying mechanisms.
    Clinical immunology (Orlando, Fla.), 2016, Volume: 166-167

    Topics: Adult; Apoptosis; Atherosclerosis; B-Lymphocytes; Biomarkers; Carotid Intima-Media Thickness; CD3 Co

2016
Increased prevalence of vulnerable atherosclerotic plaques and low levels of natural IgM antibodies against phosphorylcholine in patients with systemic lupus erythematosus.
    Arthritis research & therapy, 2010, Volume: 12, Issue:6

    Topics: Autoantibodies; Autoantigens; Carotid Arteries; Enzyme-Linked Immunosorbent Assay; Female; Humans; I

2010