phosphorylcholine has been researched along with Astrocytoma in 6 studies
Phosphorylcholine: Calcium and magnesium salts used therapeutically in hepatobiliary dysfunction.
phosphocholine : The phosphate of choline; and the parent compound of the phosphocholine family.
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous ex vivo spectroscopic data from tissue samples revealed differences in phospholipid metabolites between isocitrate dehydrogenase mutated (IDHmut) and IDH wildtype (IDHwt) gliomas." | 3.91 | In vivo Metabolic Profiles as Determined by ( Bähr, O; Franz, K; Hattingen, E; Pilatus, U; Steinbach, J; Wenger, KJ, 2019) |
| "High-grade gliomas (WHO grade III anaplastic astrocytoma and grade IV glioblastoma multiforme) are the most common primary tumors in the central nervous system in adults." | 2.45 | High-grade glioma mouse models and their applicability for preclinical testing. ( Beijnen, JH; de Vries, NA; van Tellingen, O, 2009) |
| "Glycine was detected in 24% of all studies, though with a wide range of signal amplitude and extent of the spatial distributions." | 1.40 | Mapping of glycine distributions in gliomas. ( Behari, S; Gupta, RK; Hussain, N; Maudsley, AA; Parra, NA; Roy, B; Sheriff, S; Stoyanova, R, 2014) |
| " Moreover, activity of the survival kinase PKB/Akt was downregulated upon treatment with ErPC/ErPC3 alone or in combination with ionizing radiation." | 1.33 | Increased cytotoxicity of ionizing radiation in combination with membrane-targeted apoptosis modulators involves downregulation of protein kinase B/Akt-mediated survival-signaling. ( Belka, C; Eibl, H; Faltin, H; Handrick, R; Jendrossek, V; Rübel, A, 2006) |
| "The pH of brain tumors (7." | 1.28 | P-31 MR spectroscopy of normal human brain and brain tumors. ( Hubesch, B; Matson, GB; Meyerhoff, DJ; Roth, K; Sappey-Marinier, D; Weiner, MW, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wenger, KJ | 1 |
| Hattingen, E | 1 |
| Franz, K | 1 |
| Steinbach, J | 1 |
| Bähr, O | 1 |
| Pilatus, U | 1 |
| Maudsley, AA | 1 |
| Gupta, RK | 1 |
| Stoyanova, R | 1 |
| Parra, NA | 1 |
| Roy, B | 1 |
| Sheriff, S | 1 |
| Hussain, N | 1 |
| Behari, S | 1 |
| de Vries, NA | 1 |
| Beijnen, JH | 1 |
| van Tellingen, O | 1 |
| Handrick, R | 1 |
| Rübel, A | 1 |
| Faltin, H | 1 |
| Eibl, H | 1 |
| Belka, C | 1 |
| Jendrossek, V | 1 |
| Hubesch, B | 1 |
| Sappey-Marinier, D | 1 |
| Roth, K | 1 |
| Meyerhoff, DJ | 1 |
| Matson, GB | 1 |
| Weiner, MW | 1 |
| Barna, BP | 1 |
| James, K | 1 |
| Deodhar, SD | 1 |
1 review available for phosphorylcholine and Astrocytoma
| Article | Year |
|---|---|
High-grade glioma mouse models and their applicability for preclinical testing.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Biomark | 2009 |
5 other studies available for phosphorylcholine and Astrocytoma
| Article | Year |
|---|---|
In vivo Metabolic Profiles as Determined by
Topics: Adult; Aged; Analysis of Variance; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; Diagnosis, Diffe | 2019 |
Mapping of glycine distributions in gliomas.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Mapping; Brain Neoplasms; Choline; Diffusion Magn | 2014 |
Increased cytotoxicity of ionizing radiation in combination with membrane-targeted apoptosis modulators involves downregulation of protein kinase B/Akt-mediated survival-signaling.
Topics: Apoptosis; Astrocytoma; Caspases; Cell Line, Tumor; Combined Modality Therapy; Down-Regulation; Enzy | 2006 |
P-31 MR spectroscopy of normal human brain and brain tumors.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain; Brain Neoplasms; Female; Humans; Image Processing, Comp | 1990 |
Activation of human monocyte tumoricidal activity by C-reactive protein.
Topics: Astrocytes; Astrocytoma; C-Reactive Protein; Carcinoma, Renal Cell; Cell Line; Cytotoxicity Tests, I | 1987 |