phosphorus-radioisotopes and Porphyrias

phosphorus-radioisotopes has been researched along with Porphyrias* in 1 studies

Other Studies

1 other study(ies) available for phosphorus-radioisotopes and Porphyrias

Article	Year
Ribonucleic acid synthesis in porphyric rat liver induced by 3,5-dicarbethoxy-1,4-dihydrocollidine. The Biochemical journal, 1973, Volume: 136, Issue:1 1. Administration of 3,5-dicarbethoxy-1,4-dihydrocollidine to rats caused a marked increase in the activity of delta-aminolaevulinic acid synthetase as well as a slight net increase in RNA in the livers. 2. 3,5-Dicarbethoxy-1,4-dihydrocollidine primarily stimulated the synthesis of RNA in the nucleus of the liver cell. 3. The decrease in RNA synthesis after administration of this drug resulted in a rapid decrease in the activity of this induced enzyme. This was also confirmed by treatment with actinomycin D. 4. From kinetic experiments on synthesis of RNA and delta-aminolaevulinic acid synthetase in vivo the induction mechanism of this enzyme was discussed. Topics: 5-Aminolevulinate Synthetase; Animals; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Dicarboxylic Acids; DNA; Enzyme Induction; Kinetics; Liver; Orotic Acid; Phosphorus Radioisotopes; Polyribosomes; Porphyrias; Proteins; Pyridines; Rats; RNA; Time Factors	1973

Article

Year

Ribonucleic acid synthesis in porphyric rat liver induced by 3,5-dicarbethoxy-1,4-dihydrocollidine.

The Biochemical journal, 1973, Volume: 136, Issue:1

1. Administration of 3,5-dicarbethoxy-1,4-dihydrocollidine to rats caused a marked increase in the activity of delta-aminolaevulinic acid synthetase as well as a slight net increase in RNA in the livers. 2. 3,5-Dicarbethoxy-1,4-dihydrocollidine primarily stimulated the synthesis of RNA in the nucleus of the liver cell. 3. The decrease in RNA synthesis after administration of this drug resulted in a rapid decrease in the activity of this induced enzyme. This was also confirmed by treatment with actinomycin D. 4. From kinetic experiments on synthesis of RNA and delta-aminolaevulinic acid synthetase in vivo the induction mechanism of this enzyme was discussed.

Topics: 5-Aminolevulinate Synthetase; Animals; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Dicarboxylic Acids; DNA; Enzyme Induction; Kinetics; Liver; Orotic Acid; Phosphorus Radioisotopes; Polyribosomes; Porphyrias; Proteins; Pyridines; Rats; RNA; Time Factors

1973