phosphorus-radioisotopes and Neoplasm-Seeding

We report a patient with well-differentiated adenocarcinoma of the endometrium who developed a recurrence in the anterior abdominal wall probably secondary to wound seeding at the time of her original surgery. She underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy. She then received 15 mCi of 32P for positive peritoneal washings. She was free of disease until 2 years later when a large lower incision mass developed. She had no evidence for intra-abdominal disease and a radical resection with a myocutaneous flap was undertaken. Radical resection for isolated metastases may be of benefit for patients with endometrial cancer. Patients with positive cytology should be observed closely for incisional recurrence.

Topics: Adenocarcinoma; Adult; Endometrial Neoplasms; Female; Humans; Neoplasm Recurrence, Local; Neoplasm Seeding; Phosphorus Radioisotopes

Topics: Abdomen; Female; Humans; Injections, Intraperitoneal; Neoplasm Seeding; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Cavity; Phosphorus Radioisotopes; Radionuclide Imaging