phosphorus-radioisotopes and Hepatic-Encephalopathy

phosphorus-radioisotopes has been researched along with Hepatic-Encephalopathy* in 3 studies

Reviews

1 review(s) available for phosphorus-radioisotopes and Hepatic-Encephalopathy

Article	Year
The application of magnetic resonance spectroscopy to the study of hepatic encephalopathy. Journal of hepatology, 1996, Volume: 25, Issue:6 Topics: Hepatic Encephalopathy; Humans; Magnetic Resonance Spectroscopy; Phosphorus Radioisotopes	1996

Other Studies

2 other study(ies) available for phosphorus-radioisotopes and Hepatic-Encephalopathy

Article	Year
Metabolic brain disease, 2016, Volume: 31, Issue:6 Chronic liver disease (CLD) leads to a spectrum of neuropsychiatric disorders named hepatic encephalopathy (HE). Even though brain energy metabolism is believed to be altered in chronic HE, few studies have explored energy metabolism in CLD-induced HE, and their findings were inconsistent. The aim of this study was to characterize for the first time in vivo and longitudinally brain metabolic changes in a rat model of CLD-induced HE with a focus on energy metabolism, using the methodological advantages of high field proton and phosphorus Magnetic Resonance Spectroscopy ( Topics: Animals; Brain; Energy Metabolism; Hepatic Encephalopathy; Magnetic Resonance Spectroscopy; Male; Phosphorus Radioisotopes; Protons; Rats; Rats, Wistar	2016
Effect of acute thioacetamide administration on rat brain phospholipid metabolism. Neurochemical research, 1990, Volume: 15, Issue:9 Brain phospholipid composition and the [32P]orthophosphate incorporation into brain phospholipids of control and rats treated for 3 days with thioacetamide were studied. Brain phospholipid content, phosphatidylcholine, phosphatidylethanolamine, lysolecithin and phosphatidic acid did not show any significant change by the effect of thioacetamide. In contrast, thioacetamide induced a significant decrease in the levels of phosphatidylserine, sphingomyelin, phosphatidylinositol and diphosphatidylglycerol. After 75 minutes of intraperitoneal label injection, specific radioactivity of all the above phospholipids with the exception of phosphatidylethanolamine and phosphatidylcholine significantly increased. After 13 hours of isotope administration the specific radioactivity of almost all studied phospholipid classes was elevated, except for phosphatidic acid, the specific radioactivity of which did not change and for diphosphatidylglycerol which showed a decrease in specific radioactivity. These results suggest that under thioacetamide treatment brain phospholipids undergo metabolic transformations that may contribute to the hepatic encephalopathy induced by thioacetamide. Topics: Alanine Transaminase; Animals; Brain; Hepatic Encephalopathy; Male; Phosphates; Phospholipids; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors	1990

Article

Year

Metabolic brain disease, 2016, Volume: 31, Issue:6

Chronic liver disease (CLD) leads to a spectrum of neuropsychiatric disorders named hepatic encephalopathy (HE). Even though brain energy metabolism is believed to be altered in chronic HE, few studies have explored energy metabolism in CLD-induced HE, and their findings were inconsistent. The aim of this study was to characterize for the first time in vivo and longitudinally brain metabolic changes in a rat model of CLD-induced HE with a focus on energy metabolism, using the methodological advantages of high field proton and phosphorus Magnetic Resonance Spectroscopy (

Topics: Animals; Brain; Energy Metabolism; Hepatic Encephalopathy; Magnetic Resonance Spectroscopy; Male; Phosphorus Radioisotopes; Protons; Rats; Rats, Wistar

2016

Effect of acute thioacetamide administration on rat brain phospholipid metabolism.

Neurochemical research, 1990, Volume: 15, Issue:9

Brain phospholipid composition and the [32P]orthophosphate incorporation into brain phospholipids of control and rats treated for 3 days with thioacetamide were studied. Brain phospholipid content, phosphatidylcholine, phosphatidylethanolamine, lysolecithin and phosphatidic acid did not show any significant change by the effect of thioacetamide. In contrast, thioacetamide induced a significant decrease in the levels of phosphatidylserine, sphingomyelin, phosphatidylinositol and diphosphatidylglycerol. After 75 minutes of intraperitoneal label injection, specific radioactivity of all the above phospholipids with the exception of phosphatidylethanolamine and phosphatidylcholine significantly increased. After 13 hours of isotope administration the specific radioactivity of almost all studied phospholipid classes was elevated, except for phosphatidic acid, the specific radioactivity of which did not change and for diphosphatidylglycerol which showed a decrease in specific radioactivity. These results suggest that under thioacetamide treatment brain phospholipids undergo metabolic transformations that may contribute to the hepatic encephalopathy induced by thioacetamide.

Topics: Alanine Transaminase; Animals; Brain; Hepatic Encephalopathy; Male; Phosphates; Phospholipids; Phosphorus Radioisotopes; Rats; Rats, Inbred Strains; Thioacetamide; Time Factors

1990