phosphorus-radioisotopes and Antiphospholipid-Syndrome

phosphorus-radioisotopes has been researched along with Antiphospholipid-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for phosphorus-radioisotopes and Antiphospholipid-Syndrome

Article	Year
Patients with essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis. Thrombosis and haemostasis, 2002, Volume: 87, Issue:5 A significant proportion of patients with Essential Thrombocythaemia (ET) have thrombotic complications which have an important impact upon the quality, and duration of their life. We performed a retrospective cross sectional study of the prevalence of antiphospholipid antibodies (APA) in 68 ET patients. Compared to 200 "elderly" controls (>50 years) there was a significant increase in anticardiolipin IgM (p < 0.0001) and anti beta2 glycoprotein I (anti-beta2GPI) IgM (p < 0.0001) antibodies in ET. Thrombosis occurred in 10/20 with APA and 12/48 without, p = 0.04, relative risk 2.0 (95% confidence intervals 1.03-3.86): these patients did not differ in terms of other clinical features. The prevalence of thrombosis in patients with dual APA (6/7) was significant when compared to those with single APA (p = 0.02) and the remaining patients (p < 0.0002). Also anti-beta2GP1 IgM antibodies either alone, or in combination with another APA, were associated with thrombosis (p = 0.02). These results suggest that the prevalence of APA in ET and their influence upon thrombotic risk merit investigation in a larger study. Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Antibody Specificity; Antiphospholipid Syndrome; Autoantigens; Autoimmune Diseases; beta 2-Glycoprotein I; beta 2-Microglobulin; Child; Clone Cells; Cross-Sectional Studies; Female; Glycoproteins; Humans; Immunoglobulin G; Immunoglobulin M; Interferon-alpha; Male; Middle Aged; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Prevalence; Retrospective Studies; Thrombocythemia, Essential; Thrombophilia; Thrombosis	2002

Article

Year

Patients with essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis.

Thrombosis and haemostasis, 2002, Volume: 87, Issue:5

A significant proportion of patients with Essential Thrombocythaemia (ET) have thrombotic complications which have an important impact upon the quality, and duration of their life. We performed a retrospective cross sectional study of the prevalence of antiphospholipid antibodies (APA) in 68 ET patients. Compared to 200 "elderly" controls (>50 years) there was a significant increase in anticardiolipin IgM (p < 0.0001) and anti beta2 glycoprotein I (anti-beta2GPI) IgM (p < 0.0001) antibodies in ET. Thrombosis occurred in 10/20 with APA and 12/48 without, p = 0.04, relative risk 2.0 (95% confidence intervals 1.03-3.86): these patients did not differ in terms of other clinical features. The prevalence of thrombosis in patients with dual APA (6/7) was significant when compared to those with single APA (p = 0.02) and the remaining patients (p < 0.0002). Also anti-beta2GP1 IgM antibodies either alone, or in combination with another APA, were associated with thrombosis (p = 0.02). These results suggest that the prevalence of APA in ET and their influence upon thrombotic risk merit investigation in a larger study.

Topics: Adult; Aged; Aged, 80 and over; Alkylating Agents; Antibodies, Anticardiolipin; Antibodies, Antiphospholipid; Antibody Specificity; Antiphospholipid Syndrome; Autoantigens; Autoimmune Diseases; beta 2-Glycoprotein I; beta 2-Microglobulin; Child; Clone Cells; Cross-Sectional Studies; Female; Glycoproteins; Humans; Immunoglobulin G; Immunoglobulin M; Interferon-alpha; Male; Middle Aged; Phosphorus Radioisotopes; Platelet Aggregation Inhibitors; Prevalence; Retrospective Studies; Thrombocythemia, Essential; Thrombophilia; Thrombosis

2002