phosphoribosyl pyrophosphate has been researched along with Gout in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (87.88) | 18.7374 |
| 1990's | 2 (6.06) | 18.2507 |
| 2000's | 2 (6.06) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawasugi, K; Takeuchi, F | 1 |
| ASHTON, DM; JONES, OW; WYNGAARDEN, JB | 1 |
| Balis, ME; Yip, LC; Yü, TF | 1 |
| Hankiewicz, J | 1 |
| Becker, MA; Itkin, P; Losman, MJ; Simkin, PA | 1 |
| Anderson, PJ; Chang, HC; Esty, AC; Friedmann, T; Jolly, DJ; Jones, OW; Miller, AD; Plent, MM; Seegmiller, JE; Willis, RC | 1 |
| Carter, RJ; Chudley, AE; Fung, E; Lowe, JK; MacLeod, PM; Snyder, FF | 1 |
| Simkin, PA; Wisner, DE | 1 |
| Gutensohn, W | 1 |
| Tatibana, M | 1 |
| Fujimori, S | 1 |
| Bromberg, Y; Feinstein, S; Frishberg, Y; Sperling, O; Zoref-Shani, E | 1 |
| Mertz, DP | 1 |
| De Vries, A; Sperling, O; Zoref, E | 1 |
| Boer, P; Brosh, S; de Vries, A; Elazar, E; Sperling, O; Szeinberg, A | 1 |
| Becker, MA | 2 |
| Balis, ME | 1 |
| Marcolongo, R; Micheli, V; Pompucci, G | 2 |
| Tax, WJ; Veerkamp, JH | 1 |
| Boer, P; Brosh, S; de Vries, A; Sperling, O; Zoref, E | 2 |
| Holmes, EW; Wyngaarden, JB | 1 |
| Schretlen, ED; Tax, WJ; Veerkamp, JH | 1 |
| Bakay, B; Becker, MA; Borden, M; Lesh, P; Sweetman, L | 1 |
| Hershfield, MS; Seegmiller, JE | 1 |
| Astrin, K; Brenton, D; Cruikshank, M; Lever, J; Nuki, G; Seegmiller, JE | 1 |
| Levinson, DJ; Sorensen, LB | 1 |
| Boer, P; Brosh, S; De Vries, A; Elazar, E; Pinkhas, J; Sperling, O; Szeinberg, A | 1 |
| Nuki, G; Rylance, HJ; Wallace, RC | 1 |
| Becker, MA; Jimenez, ML; Kim, M; Mateos, FA; Puig, JG; Simmonds, HA | 1 |
| Watts, RW | 1 |
8 review(s) available for phosphoribosyl pyrophosphate and Gout
| Article | Year |
|---|---|
[PRPP synthetase superactivity].
Topics: Chromosomes, Human, X; Genes, Dominant; Gout; Humans; Hyperuricemia; Mutation, Missense; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Ribose-Phosphate Pyrophosphokinase | 2003 |
[Mammalian phosphoribosylpyrophosphate synthetase].
Topics: Amino Acid Sequence; Animals; Catalysis; Gout; Humans; Molecular Sequence Data; Phosphoribosyl Pyrophosphate; Protein Binding; Proteins; Rats; Ribose-Phosphate Pyrophosphokinase; Uric Acid | 1996 |
[PRPP synthetase superactivity].
Topics: Gout; Humans; Phosphoribosyl Pyrophosphate; Proteins; Purine Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Ribose-Phosphate Pyrophosphokinase; Uric Acid; X Chromosome | 1996 |
[Theory of pathogenesis in primary hyperuricamia].
Topics: Adenosine Monophosphate; Adult; Child; Female; Glucosephosphates; Glycine; Gout; Humans; Kidney; Lesch-Nyhan Syndrome; Liver; Male; Menstruation; Metabolic Diseases; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribose-Phosphate Pyrophosphokinase; Sex Factors; Uric Acid | 1975 |
Uric acid metabolism in man.
Topics: Adenine Phosphoribosyltransferase; Adenosine; Adenosine Deaminase; Animals; Cells, Cultured; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Lesch-Nyhan Syndrome; Lymphocytes; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Rats; Ribose-Phosphate Pyrophosphokinase; Sex Chromosomes; Uric Acid; Xanthines | 1976 |
Molecular nature of enzyme regulation in purine biosynthesis.
Topics: Amidophosphoribosyltransferase; Animals; Female; Glucosephosphate Dehydrogenase Deficiency; Glutamine; Gout; Humans; Inosine Monophosphate; Kinetics; Liver; Molecular Weight; Nucleotidases; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Phosphotransferases; Placenta; Pregnancy; Purine Nucleotides; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates; Xanthine Oxidase | 1977 |
Gout and the regulation of purine biosynthesis.
Topics: Adenine; Amidophosphoribosyltransferase; Cell Line; Gout; Guanine; Humans; Hypoxanthines; Kinetics; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines | 1976 |
Molecular variation in relation to purine metabolism.
Topics: Amidophosphoribosyltransferase; Chemical Phenomena; Chemistry; Glucosephosphate Dehydrogenase Deficiency; Glutathione Reductase; Gout; Humans; Inosine Monophosphate; Lesch-Nyhan Syndrome; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Uric Acid; Xanthine Oxidase; Xanthines; Xeroderma Pigmentosum | 1974 |
25 other study(ies) available for phosphoribosyl pyrophosphate and Gout
| Article | Year |
|---|---|
Accelerated turnover of phosphoribosylpyrophosphate, a purine nucleotide precursor, in certain gouty subjects.
Topics: Gout; Nucleosides; Nucleotides; Phosphoribosyl Pyrophosphate; Purine Nucleotides | 1962 |
Aspect of purine metabolic aberration associated with uric acid overproduction and gout.
Topics: Diphosphoglyceric Acids; Erythrocytes; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Leukocytes; Phosphoribosyl Pyrophosphate; Purines; Ribose-Phosphate Pyrophosphokinase; Uric Acid | 1980 |
[Hyperuricemia].
Topics: Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Male; Phosphoribosyl Pyrophosphate; Purines; Uric Acid | 1980 |
Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate.
Topics: Adult; Aged; Erythrocytes; Female; Gout; Humans; Kinetics; Male; Pedigree; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purines; Ribose-Phosphate Pyrophosphokinase; Sex Factors; Skin; Uric Acid | 1982 |
Partial phenotypic correction of human Lesch-Nyhan (hypoxanthine-guanine phosphoribosyltransferase-deficient) lymphoblasts with a transmissible retroviral vector.
Topics: Animals; B-Lymphocytes; DNA; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Male; Mice; Phenotype; Phosphoribosyl Pyrophosphate; Purines; Repetitive Sequences, Nucleic Acid; Retroviridae; Thioguanine; Transcription, Genetic; Transfection | 1984 |
Partial deficiency of hypoxanthine-guanine phosphoribosyltransferase with reduced affinity for PP-ribose-P in four related males with gout.
Topics: Adult; Erythrocytes; Female; Gout; Heterozygote; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Male; Middle Aged; Pedigree; Pentosephosphates; Phosphoribosyl Pyrophosphate | 1984 |
Management of gout and hyperuricemia.
Topics: Allopurinol; Anti-Inflammatory Agents; Colchicine; Gout; Humans; Indomethacin; Kidney; Patient Education as Topic; Phenylbutazone; Phosphoribosyl Pyrophosphate; Probenecid; Purines; Uric Acid; Uricosuric Agents | 1984 |
Inherited disorders of purine metabolism--underlying molecular mechanisms.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Molecular Biology; Mutation; Phosphoribosyl Pyrophosphate; Purine-Nucleoside Phosphorylase; Purine-Pyrimidine Metabolism, Inborn Errors; Purines; Ribose-Phosphate Pyrophosphokinase; Uric Acid | 1984 |
Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations.
Topics: Acute Kidney Injury; Adenine; Cells, Cultured; Child, Preschool; Culture Media, Conditioned; DNA Mutational Analysis; Fibroblasts; Gout; Humans; Hypoxanthine; Hypoxanthine Phosphoribosyltransferase; Jews; Lymphocytes; Male; Nucleic Acids; Nucleotides; Phosphoribosyl Pyrophosphate; Purines; Syndrome; Uric Acid | 2000 |
Mutant feedback-resistant phosphoribosylpyrophosphate synthetase associated with purine overproduction and gout. Phosphoribosylpyrophosphate and purine metabolism in cultured fibroblasts.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Erythrocytes; Feedback; Female; Fibroblasts; Genes; Gout; Humans; Male; Mutation; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purine Nucleotides; Ribose-Phosphate Pyrophosphokinase; Uric Acid | 1975 |
Normal activity of metabolic pathways involved in the formation and utilization of phosphoribosylpyrophosphate in erythrocytes of patients with primary metabolic gout.
Topics: Adenine Phosphoribosyltransferase; Erythrocytes; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase | 1975 |
Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
Topics: Adenine Phosphoribosyltransferase; Adolescent; Adult; Cells, Cultured; Erythrocytes; Female; Fibroblasts; Glycine; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Middle Aged; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purine-Pyrimidine Metabolism, Inborn Errors; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates; Uric Acid | 1976 |
Fibroblast phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in gout with purine overproduction.
Topics: Cells, Cultured; Erythrocytes; Fibroblasts; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purines; Ribose-Phosphate Pyrophosphokinase; Ribosemonophosphates; Uric Acid | 1977 |
Familial distribution of increased erythrocyte PP-ribose-P levels.
Topics: Adult; Aged; Amidophosphoribosyltransferase; Erythrocytes; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Leukocytes; Male; Middle Aged; Pedigree; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase; Uric Acid | 1977 |
A simple and sensitive method for estimating the concentration and synthesis of 5-phosphoribosyl 1-pyrophosphate in red blood cells.
Topics: Carbon Radioisotopes; Erythrocytes; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Methods; Microchemistry; Pentosephosphates; Phosphoribosyl Pyrophosphate; Ribose-Phosphate Pyrophosphokinase | 1977 |
Overproduction disease in man due to enzyme feedback resistance mutation. Purine overproduction in gout due to excessive activity of mutant feedback-resistant phosphoribosylpyrophosphate synthetase.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Feedback; Female; Genetic Linkage; Gout; Humans; Male; Mutation; Phosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purines; Ribose-Phosphate Pyrophosphokinase; X Chromosome | 1978 |
Superactivity of phosphoribosylpyrophosphate synthetase, due to feedback resistance, causing purine overproduction and gout.
Topics: Adolescent; Adult; Aged; Amidophosphoribosyltransferase; Child; Child, Preschool; Erythrocytes; Feedback; Female; Fibroblasts; Gout; Humans; Male; Phosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purine Nucleotides; Purines; Ribose-Phosphate Pyrophosphokinase; Uric Acid | 1977 |
The urinary excretion of orotic acid and orotidine, measured by an isotope dilution assay.
Topics: Adolescent; Adult; Aging; Allopurinol; Breast Feeding; Child; Female; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Infant, Newborn; Orotate Phosphoribosyltransferase; Orotic Acid; Phosphoribosyl Pyrophosphate; Pregnancy; Radioisotope Dilution Technique; Uridine | 1978 |
Diminished affinity for purine substrates as a basis for gout with mild deficiency of hypoxanthine-guanine phosphoribosyltransferase.
Topics: Azaguanine; Binding Sites; Drug Resistance; Erythrocytes; Fibroblasts; Gout; Guanine; Heterozygote; Humans; Hypoxanthine Phosphoribosyltransferase; Hypoxanthines; Kinetics; Lesch-Nyhan Syndrome; Phosphoribosyl Pyrophosphate | 1977 |
Purine and pyrimidine nucleotide concentrations in cells with decreased hypoxanthine-guanine-phosphoribosyltransferase (HGPRT) activity.
Topics: Cell Line; Erythrocytes; Fibroblasts; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Lymphocytes; Mutation; Phosphates; Phosphoribosyl Pyrophosphate; Purine Nucleotides; Purines; Pyrimidine Nucleotides | 1977 |
Origin and extrarenal elimination of uric acid in man.
Topics: Amidophosphoribosyltransferase; Dietary Proteins; Glutamine; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Kidney; Kidney Failure, Chronic; Phosphoribosyl Pyrophosphate; Purines; Uric Acid | 1975 |
Proceedings: Erythrocytic pathways regulating phosphoribosylpyrophosphate availability in primary metabolic gout and in polycythemia vera.
Topics: Erythrocytes; Gout; Humans; Pentosephosphates; Phosphoribosyl Pyrophosphate; Polycythemia Vera | 1975 |
[Behavior of 5-phosphoribosyl-1-pyrophosphate (PRPP) in erythrocytes, leukocytes and lymphocytes of normal and gouty subjects].
Topics: Adult; Aged; Allopurinol; Erythrocytes; Gout; Humans; Leukocytes; Lymphocytes; Middle Aged; Pentosephosphates; Phosphoribosyl Pyrophosphate; Purines; Uric Acid | 1975 |
A method for the determination of 5-phosphoribosyl 1-pyrophosphate concentrations in erythrocytes using high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Erythrocytes; Gout; Humans; Hypoxanthine Phosphoribosyltransferase; Inosine Monophosphate; Male; Pentosephosphates; Phosphoribosyl Pyrophosphate | 1987 |
Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase.
Topics: Adult; Cells, Cultured; Child; Deafness; Enzyme Activation; Female; Fibroblasts; Gout; Humans; Kinetics; Male; Pedigree; Pentosephosphates; Phosphoribosyl Pyrophosphate; Phosphotransferases; Purine Nucleotides; Purine-Pyrimidine Metabolism, Inborn Errors; Ribose-Phosphate Pyrophosphokinase | 1989 |