phosphonoacetic acid has been researched along with Skin Diseases, Infectious in 10 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
Skin Diseases, Infectious: Skin diseases caused by bacteria, fungi, parasites, or viruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phosphonoacetic acid (PAA) was evaluated as therapy for primary cutaneous herpes simplex virus (HSV) infections in guinea pigs." | 7.66 | Topical phosphonoacetic acid treatment of cutaneous herpes simplex infections in the guinea pig. ( Jarratt, MT; McCarty, JR, 1979) |
| "To determine whether foscarnet has potential efficacy in the treatment of acyclovir-resistant mucocutaneous varicella-zoster infection in patients with the acquired immunodeficiency syndrome (AIDS)." | 3.68 | Foscarnet therapy in five patients with AIDS and acyclovir-resistant varicella-zoster virus infection. ( Berger, TG; Biron, KK; Gilson, I; Mills, J; Safrin, S; Wofsy, CB; Wolfe, PR, 1991) |
| "The herpesvirus DNA polymerase inhibitor foscarnet, applied topically, and the anti-herpesvirus guanosine analogue buciclovir, given orally, decreased virus replication and disease development in primary skin infections of mice caused by herpes simplex virus type 1 (HSV-1)." | 3.67 | Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease. ( Datema, R; Ericson, AC; Kristofferson, A; Sohl-Akerlund, A, 1988) |
| "Phosphonoacetic acid (PAA) was evaluated as therapy for primary cutaneous herpes simplex virus (HSV) infections in guinea pigs." | 3.66 | Topical phosphonoacetic acid treatment of cutaneous herpes simplex infections in the guinea pig. ( Jarratt, MT; McCarty, JR, 1979) |
| "Phosphonoacetic acid was the only compound with a good therapeutic activity against herpesvirus infection, causing a reduction of both the cumulative score and the time to healing." | 1.26 | Comparison of the therapeutic effects of five antiviral agents on cutaneous herpesvirus infection in guinea pigs. ( Alenius, S; Oberg, B, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Poryo, A | 1 |
| Wigand, R | 2 |
| Burkhardt, U | 1 |
| Alenius, S | 2 |
| Dinter, Z | 1 |
| Oberg, B | 2 |
| McCarty, JR | 1 |
| Jarratt, MT | 1 |
| Safrin, S | 1 |
| Berger, TG | 1 |
| Gilson, I | 1 |
| Wolfe, PR | 1 |
| Wofsy, CB | 1 |
| Mills, J | 1 |
| Biron, KK | 1 |
| Smith, KJ | 1 |
| Kahlter, DC | 1 |
| Davis, C | 1 |
| James, WD | 1 |
| Skelton, HG | 1 |
| Angritt, P | 1 |
| Arbesfeld, DM | 1 |
| Thomas, I | 1 |
| Chatis, PA | 1 |
| Miller, CH | 1 |
| Schrager, LE | 1 |
| Crumpacker, CS | 1 |
| Kristofferson, A | 1 |
| Ericson, AC | 1 |
| Sohl-Akerlund, A | 1 |
| Datema, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-centered, Randomized Study to Evaluate the Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection Compared to Intravenous Acyclovir in Patients With Herpes Zoster From China[NCT02151240] | Phase 4 | 94 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for phosphonoacetic acid and Skin Diseases, Infectious
| Article | Year |
|---|---|
Cutaneous herpes simplex virus infections.
Topics: Acyclovir; Administration, Oral; Antiviral Agents; Diagnosis, Differential; Drug Resistance, Microbi | 1991 |
9 other studies available for phosphonoacetic acid and Skin Diseases, Infectious
| Article | Year |
|---|---|
Cutaneous herpes simplex virus infection of the guinea pig: lack of resistance to acyclovir and phosphonoformic acid after topical treatment.
Topics: Acyclovir; Administration, Topical; Animals; Drug Resistance, Microbial; Drug Therapy, Combination; | 1984 |
Combined chemotherapy of cutaneous herpes simplex infection of the guinea pig.
Topics: Acyclovir; Animals; Antiviral Agents; Arabinonucleosides; Deoxyuridine; Drug Therapy, Combination; F | 1983 |
Therapeutic effect of trisodium phosphonoformate on cutaneous herpesvirus infection in guinea pigs.
Topics: Animals; Antiviral Agents; Formates; Guinea Pigs; Herpesviridae Infections; Male; Organophosphorus C | 1978 |
Topical phosphonoacetic acid treatment of cutaneous herpes simplex infections in the guinea pig.
Topics: Animals; Croton Oil; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Guinea Pigs; Herp | 1979 |
Comparison of the therapeutic effects of five antiviral agents on cutaneous herpesvirus infection in guinea pigs.
Topics: Animals; Antiviral Agents; Cytarabine; Guinea Pigs; Herpes Simplex; Idoxuridine; Phosphonoacetic Aci | 1978 |
Foscarnet therapy in five patients with AIDS and acyclovir-resistant varicella-zoster virus infection.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Cohort Studies; Drug Resista | 1991 |
Acyclovir-resistant varicella zoster responsive to foscarnet.
Topics: Acyclovir; Adult; Antiviral Agents; Drug Resistance, Microbial; Foscarnet; Herpes Zoster; Herpesviru | 1991 |
Successful treatment with foscarnet of an acyclovir-resistant mucocutaneous infection with herpes simplex virus in a patient with acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Drug Resistance, Microbial; | 1989 |
Limited efficacy of inhibitors of herpes simplex virus DNA synthesis in murine models of recrudescent disease.
Topics: Acyclovir; Administration, Oral; Administration, Topical; Animals; Antiviral Agents; Disease Models, | 1988 |