phosphonoacetic acid has been researched along with Shingles in 9 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine whether foscarnet has potential efficacy in the treatment of acyclovir-resistant mucocutaneous varicella-zoster infection in patients with the acquired immunodeficiency syndrome (AIDS)." | 3.68 | Foscarnet therapy in five patients with AIDS and acyclovir-resistant varicella-zoster virus infection. ( Berger, TG; Biron, KK; Gilson, I; Mills, J; Safrin, S; Wofsy, CB; Wolfe, PR, 1991) |
| " These questions concern appropriate routes of administration for antiviral compounds, optimal dosage regimens, risks of long-term prophylaxis, and the emergence of resistant organisms." | 2.66 | Antiviral chemotherapy and chemoprophylaxis. ( Dolin, R, 1985) |
| "Acyclovir is a prototype of this improved process." | 2.37 | Promising new antiviral drugs. ( Bryson, YJ, 1988) |
| " The dosage of Foscarnet was increased during the study." | 1.27 | Clinical experiences with phosphonoformate (foscarnet) treatment of viral diseases following renal transplantation. ( Ahlmén, J; Brynger, H; Lycke, E; Wijnween, AC, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arvin, AM | 1 |
| Martin, DP | 1 |
| Gard, EA | 1 |
| Merigan, TC | 1 |
| St Geme, JW | 1 |
| Masur, H | 1 |
| Safrin, S | 1 |
| Berger, TG | 1 |
| Gilson, I | 1 |
| Wolfe, PR | 1 |
| Wofsy, CB | 1 |
| Mills, J | 1 |
| Biron, KK | 1 |
| Smith, KJ | 1 |
| Kahlter, DC | 1 |
| Davis, C | 1 |
| James, WD | 1 |
| Skelton, HG | 1 |
| Angritt, P | 1 |
| Moeland, A | 1 |
| Bruun, JN | 1 |
| Bryson, YJ | 1 |
| Dolin, R | 1 |
| Ahlmén, J | 1 |
| Wijnween, AC | 1 |
| Brynger, H | 1 |
| Lycke, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-centered, Randomized Study to Evaluate the Efficacy and Safety of Foscarnet Sodium and Sodium Chloride Injection Compared to Intravenous Acyclovir in Patients With Herpes Zoster From China[NCT02151240] | Phase 4 | 94 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for phosphonoacetic acid and Shingles
| Article | Year |
|---|---|
Therapeutic control of viral infections: chemotherapy, interferon and gamma globulin.
Topics: Amantadine; Animals; Benzimidazoles; Chickenpox; Cytarabine; gamma-Globulins; Hepatitis, Viral, Huma | 1979 |
[Treatment of herpesvirus infections].
Topics: Acyclovir; Antiviral Agents; Cytomegalovirus Infections; Drug Resistance, Microbial; Foscarnet; Ganc | 1991 |
Promising new antiviral drugs.
Topics: Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cytomegalovirus Infections; Foscarnet; Ganc | 1988 |
1 trial available for phosphonoacetic acid and Shingles
| Article | Year |
|---|---|
Antiviral chemotherapy and chemoprophylaxis.
Topics: Acyclovir; Adult; Aged; Amantadine; Antiviral Agents; Chickenpox; Clinical Trials as Topic; Cytomega | 1985 |
5 other studies available for phosphonoacetic acid and Shingles
| Article | Year |
|---|---|
Interferon prophylaxis against simian varicella in Erythrocebus patas monkeys.
Topics: Animals; Antibodies, Viral; Disease Models, Animal; Erythrocebus patas; Female; Herpes Zoster; Herpe | 1983 |
Clinical implications of herpesvirus infections in patients with AIDS. Introduction.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi | 1992 |
Foscarnet therapy in five patients with AIDS and acyclovir-resistant varicella-zoster virus infection.
Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Antiviral Agents; Cohort Studies; Drug Resista | 1991 |
Acyclovir-resistant varicella zoster responsive to foscarnet.
Topics: Acyclovir; Adult; Antiviral Agents; Drug Resistance, Microbial; Foscarnet; Herpes Zoster; Herpesviru | 1991 |
Clinical experiences with phosphonoformate (foscarnet) treatment of viral diseases following renal transplantation.
Topics: Adult; Aged; Antiviral Agents; Cytomegalovirus Infections; Female; Foscarnet; Herpes Simplex; Herpes | 1985 |