phosphonoacetic acid has been researched along with Osteogenic Sarcoma in 2 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Another solid tumor, Ridgway osteogenic sarcoma, which is sensitivie to many established chemotherapeutic agents, did not respond to PALA." | 1.26 | Antitumor activity of N-(phosphonacetyl)-L-aspartic acid, a transition-state inhibitor of aspartate transcarbamylase. ( Goldin, A; Inouye, T; Johnson, RK; Stark, GR, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Hizawi, S | 1 |
| Lagowski, JP | 1 |
| Kulesz-Martin, M | 1 |
| Albor, A | 1 |
| Johnson, RK | 1 |
| Inouye, T | 1 |
| Goldin, A | 1 |
| Stark, GR | 1 |
2 other studies available for phosphonoacetic acid and Osteogenic Sarcoma
| Article | Year |
|---|---|
Induction of gene amplification as a gain-of-function phenotype of mutant p53 proteins.
Topics: Aspartic Acid; Bone Neoplasms; Camptothecin; DNA Topoisomerases, Type I; Enzyme Inhibitors; Gene Amp | 2002 |
Antitumor activity of N-(phosphonacetyl)-L-aspartic acid, a transition-state inhibitor of aspartate transcarbamylase.
Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; D | 1976 |