Page last updated: 2024-10-17

phosphonoacetic acid and Neuroretinitis

phosphonoacetic acid has been researched along with Neuroretinitis in 62 studies

Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.

Research Excerpts

ExcerptRelevanceReference
"In a controlled trial of foscarnet in the treatment of cytomegalovirus (CMV) retinitis in patients with the acquired immunodeficiency syndrome (AIDS), patients with non-immediately sight-threatening lesions were randomized to receive immediate treatment with foscarnet or foscarnet treatment delayed until the first signs of retinitis progression."9.07Design of a randomized controlled trial of foscarnet in patients with cytomegalovirus retinitis associated with acquired immunodeficiency syndrome. ( Polis, MA, 1992)
"We performed a multicenter, randomized, unblinded clinical trial (the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial) designed to compare ganciclovir with foscarnet in the treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome (AIDS)."9.07Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis. ( , 1992)
"Circulating human immunodeficiency virus (HIV) p24 antigen levels were measured in 22 AIDS patients who had detectable serum antigen at baseline after induction and maintenance therapy of foscarnet for cytomegalovirus retinitis in phase I/II multicenter trials."9.07Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis. ( Causey, DM; Davis, RB; Grieco, MH; Hooton, TM; Jacobson, MA; McKinley, GF; Parenti, DM; Reddy, MM; van der Horst, CM, 1992)
"To evaluate foscarnet sodium in treating cytomegalovirus retinitis in patients with AIDS."9.07A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS. ( Baird, BF; Davey, RT; Davis, M; De Smet, MD; Falloon, J; Kovacs, JA; Palestine, AG; Polis, MA; Zunich, KM; Zurlo, JJ, 1991)
"Ganciclovir and Foscarnet were compared in an open randomised trial as treatment and secondary prophylaxis of cytomegalovirus (CMV) retinitis in patients with AIDS."9.07Foscarnet and Ganciclovir in the treatment of CMV retinitis in AIDS patients: a randomised comparison. ( Gazzard, BG; Harman, C; Mathalone, B; Mitchell, S; Moyle, G, 1992)
"The use of ganciclovir in the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS) is limited by marrow toxicity and by the development of resistance to this agent in CMV strains capable of causing progressive disease."8.78Maintenance therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: foscarnet. ( Jacobson, MA, 1992)
"Induction regimens of foscarnet and ganciclovir are highly effective in arresting cytomegalovirus (CMV) retinitis in patients with AIDS."8.78Foscarnet and ganciclovir in the treatment of cytomegalovirus retinitis. ( Polis, MA, 1992)
"The pyrophosphate analogue, foscarnet, selectively inhibits the DNA polymerase of human herpes viruses, including cytomegalovirus, and the reverse transcriptase of HIV."8.78Foscarnet. A review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis. ( Chrisp, P; Clissold, SP, 1991)
"Infections caused by cytomegalovirus (CMV) resistant in vitro to ganciclovir, defined as requiring greater than 6 mumols of ganciclovir for ED50 have developed in some AIDS patients with progressive CMV retinitis despite chronic ganciclovir therapy."7.68Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS. ( Drew, WL; Feinberg, J; Jacobson, MA; Miner, RD; O'Donnell, JJ; Parenti, D; Whitmore, PV, 1991)
"Ganciclovir and foscarnet are both effective for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome, but the benefits of either agent given alone are limited."7.68Treatment of aggressive cytomegalovirus retinitis with ganciclovir in combination with foscarnet in a child infected with human immunodeficiency virus. ( Butler, KM; De Smet, MD; Husson, RN; Jarosinski, P; Lovato, G; Manjunath, K; Montrella, K; Mueller, B; Nussenblatt, RB; Pizzo, PA, 1992)
"Foscarnet is an investigational antiviral agent that has been used effectively in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients."7.68Successful foscarnet therapy for cytomegalovirus retinitis in an AIDS patient undergoing hemodialysis: rationale for empiric dosing and plasma level monitoring. ( Gambertoglio, JG; Graziani, AL; Grunwald, JE; MacGregor, RR; Weiss, R, 1991)
" Following allogeneic bone marrow transplantation, he developed cytomegalovirus retinitis, which was treated successfully with trisodium phosphonoformate (foscarnet)."7.67Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation. ( Arthur, C; Ganly, PS; Goldman, JM; Schulenburg, WE, 1988)
"Ten patients with acquired immunodeficiency syndrome with newly diagnosed cytomegalovirus (CMV) retinitis were treated with an induction regimen of intravenous foscarnet, 60 mg/kg of body weight, administered as a 2-h infusion and repeated every 8 h for 14 days."7.67Foscarnet treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. ( Jacobson, MA; Mills, J; O'Donnell, JJ, 1989)
"Foscarnet has a low solubility and a high degree of ionization at physiologic pH, requiring it to be administered in higher doses and larger volumes."6.38Approaches to the treatment of cytomegalovirus retinitis: ganciclovir and foscarnet. ( Jacobson, MA; O'Donnell, JJ, 1991)
"Eight patients with acquired immunodeficiency syndrome and serious CMV retinitis received 2-h intravenous infusions of foscarnet at a dosage of 60 mg/kg of body weight every 8 h for 14 days."5.28Pharmacokinetics of intermittently administered intravenous foscarnet in the treatment of acquired immunodeficiency syndrome patients with serious cytomegalovirus retinitis. ( Aweeka, F; Gambertoglio, J; Jacobson, MA; Mills, J, 1989)
"Foscarnet was discontinued because of adverse events in 3 (3%) of 97 patients, with treatment being stopped in 2 patients because of renal insufficiency and in 1 patient because of an acute neurologic disorder."5.28Foscarnet induction therapy for cytomegalovirus retinitis in AIDS: comparison of twice-daily and three-times-daily regimens. ( Brancon, C; Caumes, E; Cochereau-Massin, I; Dahan, R; Dohin, E; Gentilini, M; Katlama, C; Robinet, M; Rogeaux, O, 1992)
"To evaluate foscarnet sodium in treating cytomegalovirus retinitis in patients with AIDS."5.07A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS. ( Baird, BF; Davey, RT; Davis, M; De Smet, MD; Falloon, J; Kovacs, JA; Palestine, AG; Polis, MA; Zunich, KM; Zurlo, JJ, 1991)
"Circulating human immunodeficiency virus (HIV) p24 antigen levels were measured in 22 AIDS patients who had detectable serum antigen at baseline after induction and maintenance therapy of foscarnet for cytomegalovirus retinitis in phase I/II multicenter trials."5.07Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis. ( Causey, DM; Davis, RB; Grieco, MH; Hooton, TM; Jacobson, MA; McKinley, GF; Parenti, DM; Reddy, MM; van der Horst, CM, 1992)
"Ganciclovir and Foscarnet were compared in an open randomised trial as treatment and secondary prophylaxis of cytomegalovirus (CMV) retinitis in patients with AIDS."5.07Foscarnet and Ganciclovir in the treatment of CMV retinitis in AIDS patients: a randomised comparison. ( Gazzard, BG; Harman, C; Mathalone, B; Mitchell, S; Moyle, G, 1992)
"We performed a multicenter, randomized, unblinded clinical trial (the Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial) designed to compare ganciclovir with foscarnet in the treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome (AIDS)."5.07Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis. ( , 1992)
"In a controlled trial of foscarnet in the treatment of cytomegalovirus (CMV) retinitis in patients with the acquired immunodeficiency syndrome (AIDS), patients with non-immediately sight-threatening lesions were randomized to receive immediate treatment with foscarnet or foscarnet treatment delayed until the first signs of retinitis progression."5.07Design of a randomized controlled trial of foscarnet in patients with cytomegalovirus retinitis associated with acquired immunodeficiency syndrome. ( Polis, MA, 1992)
"The use of ganciclovir in the treatment of cytomegalovirus (CMV) retinitis in patients with acquired immunodeficiency syndrome (AIDS) is limited by marrow toxicity and by the development of resistance to this agent in CMV strains capable of causing progressive disease."4.78Maintenance therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: foscarnet. ( Jacobson, MA, 1992)
" The antiviral agents ganciclovir and foscarnet are effective against CMV retinitis and gastrointestinal diseases, although dose-limiting adverse effects and the need for long-term maintenance therapy may hinder their use in many patients."4.78Treatment and prophylaxis of cytomegalovirus disease. ( Jacobson, PA; Levinson, ML, 1992)
"The pyrophosphate analogue, foscarnet, selectively inhibits the DNA polymerase of human herpes viruses, including cytomegalovirus, and the reverse transcriptase of HIV."4.78Foscarnet. A review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis. ( Chrisp, P; Clissold, SP, 1991)
"Induction regimens of foscarnet and ganciclovir are highly effective in arresting cytomegalovirus (CMV) retinitis in patients with AIDS."4.78Foscarnet and ganciclovir in the treatment of cytomegalovirus retinitis. ( Polis, MA, 1992)
"Infections caused by cytomegalovirus (CMV) resistant in vitro to ganciclovir, defined as requiring greater than 6 mumols of ganciclovir for ED50 have developed in some AIDS patients with progressive CMV retinitis despite chronic ganciclovir therapy."3.68Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS. ( Drew, WL; Feinberg, J; Jacobson, MA; Miner, RD; O'Donnell, JJ; Parenti, D; Whitmore, PV, 1991)
"Foscarnet and ganciclovir appear to be of similar effectiveness in halting active infection when given as induction therapy and in forestalling progression of disease when given as maintenance therapy in persons with AIDS who have cytomegalovirus (CMV) retinitis."3.68Therapeutic algorithm for treatment of cytomegalovirus retinitis in persons with AIDS. A roundtable summary. ( Balfour, HH; Drew, WL; Hardy, WD; Heinemann, MH; Polsky, B, 1992)
"Ganciclovir and foscarnet are both effective for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome, but the benefits of either agent given alone are limited."3.68Treatment of aggressive cytomegalovirus retinitis with ganciclovir in combination with foscarnet in a child infected with human immunodeficiency virus. ( Butler, KM; De Smet, MD; Husson, RN; Jarosinski, P; Lovato, G; Manjunath, K; Montrella, K; Mueller, B; Nussenblatt, RB; Pizzo, PA, 1992)
"Foscarnet is an investigational antiviral agent that has been used effectively in the treatment of cytomegalovirus (CMV) retinitis in AIDS patients."3.68Successful foscarnet therapy for cytomegalovirus retinitis in an AIDS patient undergoing hemodialysis: rationale for empiric dosing and plasma level monitoring. ( Gambertoglio, JG; Graziani, AL; Grunwald, JE; MacGregor, RR; Weiss, R, 1991)
"Ten patients with acquired immunodeficiency syndrome with newly diagnosed cytomegalovirus (CMV) retinitis were treated with an induction regimen of intravenous foscarnet, 60 mg/kg of body weight, administered as a 2-h infusion and repeated every 8 h for 14 days."3.67Foscarnet treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome. ( Jacobson, MA; Mills, J; O'Donnell, JJ, 1989)
" Following allogeneic bone marrow transplantation, he developed cytomegalovirus retinitis, which was treated successfully with trisodium phosphonoformate (foscarnet)."3.67Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation. ( Arthur, C; Ganly, PS; Goldman, JM; Schulenburg, WE, 1988)
"Foscarnet has a low solubility and a high degree of ionization at physiologic pH, requiring it to be administered in higher doses and larger volumes."2.38Approaches to the treatment of cytomegalovirus retinitis: ganciclovir and foscarnet. ( Jacobson, MA; O'Donnell, JJ, 1991)
" Myelosuppression may be further exacerbated in AIDS patients by such other agents as zidovudine or trimethoprim/sulfamethoxazole, often necessitating dosage reductions or discontinuation of these agents in patients receiving ganciclovir."2.38Foscarnet sodium. ( Baltz, JK; Minor, JR, 1991)
"CMV disease is a major problem in AIDS, though with a different profile from that seen in other immunosuppressed patients."2.38Cytomegalovirus infection in the acquired immune deficiency syndrome. ( Pinching, AJ, 1989)
" An important direction for future clinical research is the development of more effective and less toxic therapy, as well as orally bioavailable drugs for maintenance therapy."2.37Serious cytomegalovirus disease in the acquired immunodeficiency syndrome (AIDS). Clinical findings, diagnosis, and treatment. ( Jacobson, MA; Mills, J, 1988)
"Cytomegalovirus retinitis is probably the result of hematogenous spread of the virus to the retina after systemic reactivation of a latent cytomegalovirus infection."2.37The diagnosis of cytomegalovirus retinitis. ( Bloom, JN; Palestine, AG, 1988)
"Among 347 AIDS patients seen at St Mary's Hospital, London between 1983 and 1989, cytomegalovirus (CMV) disease was observed in 75 (22%)."1.28Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival. ( Anderson, S; Beck, EJ; Coker, R; Coleman, D; Harris, JR; Main, J; Migdal, C; Peters, BS; Pinching, AJ, 1991)
"Fifty AIDS patients were investigated for human cytomegalovirus (HCMV) viraemia when potentially HCMV-related clinical symptoms or syndromes were observed."1.28Early virus isolation, early structural antigen detection and DNA amplification by the polymerase chain reaction in polymorphonuclear leukocytes from AIDS patients with human cytomegalovirus viraemia. ( Gaballo, A; Gerna, G; Milanesi, G; Parea, M; Percivalle, E; Zavattoni, M; Zipeto, D, 1991)
"Foscarnet was discontinued because of adverse events in 3 (3%) of 97 patients, with treatment being stopped in 2 patients because of renal insufficiency and in 1 patient because of an acute neurologic disorder."1.28Foscarnet induction therapy for cytomegalovirus retinitis in AIDS: comparison of twice-daily and three-times-daily regimens. ( Brancon, C; Caumes, E; Cochereau-Massin, I; Dahan, R; Dohin, E; Gentilini, M; Katlama, C; Robinet, M; Rogeaux, O, 1992)
"Eight patients with acquired immunodeficiency syndrome and serious CMV retinitis received 2-h intravenous infusions of foscarnet at a dosage of 60 mg/kg of body weight every 8 h for 14 days."1.28Pharmacokinetics of intermittently administered intravenous foscarnet in the treatment of acquired immunodeficiency syndrome patients with serious cytomegalovirus retinitis. ( Aweeka, F; Gambertoglio, J; Jacobson, MA; Mills, J, 1989)
" Maintenance therapy with DHPG would appear to be necessary to prevent relapse, but the logistics of this are difficult, and the effective dosage of DHPG is as yet uncertain."1.27Treatment of CMV retinitis in an AIDS patient. ( Acheson, JF; Bradbeer, C; Shah, SM; Spalton, DJ; Thin, RN, 1987)

Research

Studies (62)

TimeframeStudies, this research(%)All Research%
pre-199014 (22.58)18.7374
1990's48 (77.42)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Healy, B1
Hirsch, MS1
Masur, H1
Heinemann, MH2
Polis, MA3
Jacobson, MA11
Jabs, DA1
Butler, KM1
De Smet, MD2
Husson, RN1
Mueller, B1
Manjunath, K1
Montrella, K1
Lovato, G1
Jarosinski, P1
Nussenblatt, RB1
Pizzo, PA1
Salit, IE1
Evans, JK1
Scoular, A1
Miller, RF1
Wilson, RJ1
Skolnik, PR1
Deray, G1
Katlama, C3
Jacobs, C1
Bachman, DM1
Dohin, E1
Caumes, E1
Cochereau-Massin, I1
Brancon, C1
Robinet, M2
Rogeaux, O1
Dahan, R1
Gentilini, M1
Balfour, HH1
Drew, WL2
Hardy, WD1
Polsky, B1
Evans, LM1
Grossman, ME1
Cotte, L1
Langlois, M1
Trepo, C1
Reddy, MM1
Grieco, MH1
McKinley, GF1
Causey, DM1
van der Horst, CM1
Parenti, DM1
Hooton, TM1
Davis, RB1
Levinson, ML1
Jacobson, PA1
Moyle, G1
Harman, C1
Mitchell, S1
Mathalone, B1
Gazzard, BG2
Morris, DJ1
Wood, CA1
Feinberg, J1
O'Donnell, JJ4
Whitmore, PV1
Miner, RD1
Parenti, D1
MacGregor, RR1
Graziani, AL1
Weiss, R1
Grunwald, JE1
Gambertoglio, JG1
Palestine, AG2
Baird, BF1
Falloon, J1
Kovacs, JA1
Davey, RT1
Zurlo, JJ1
Zunich, KM1
Davis, M1
Marwick, C1
Nightingale, SL1
Peters, BS1
Beck, EJ1
Anderson, S1
Coleman, D1
Coker, R1
Main, J1
Migdal, C2
Harris, JR2
Pinching, AJ2
Harb, GE1
Bacchetti, P1
Gerna, G1
Zipeto, D1
Parea, M1
Percivalle, E1
Zavattoni, M1
Gaballo, A1
Milanesi, G1
Nelson, MR1
Barter, G1
Hawkins, D1
Coker, RJ1
Tomlinson, D1
Horner, P1
Chrisp, P1
Clissold, SP1
Paul, AA1
Leeper, HF1
Friberg, TR1
Henderly, DE1
Jampol, LM1
Minor, JR1
Baltz, JK1
Fanning, MM2
Read, SE2
Benson, M1
Vas, S1
Rachlis, A2
Kozousek, V1
Mortimer, C1
Harvey, P1
Schwartz, C1
Chew, E2
Farese, RV1
Schambelan, M1
Hollander, H1
Stringari, S1
Lehoang, P1
Girard, B1
Marcel, P1
Zazoun, L1
Matheron, S1
Rozenbaum, W1
Morer, I1
Lernestedt, JO1
Mills, J4
Aweeka, F2
Gambertoglio, J2
Wood, G1
Whitby, M1
Hogan, P1
Frazer, I1
Acheson, JF1
Shah, SM1
Spalton, DJ1
Bradbeer, C1
Thin, RN1
Walmsley, SL1
Vellend, H1
Salit, I1
Crowe, S1
Levy, J1
McManus, N1
Bloom, JN1
Ganly, PS1
Arthur, C1
Goldman, JM1
Schulenburg, WE2
Heley, A1
Singer, DR1
Fallon, TJ1
Williams, G1
Cohen, J1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Foscarnet-Ganciclovir CMV Retinitis Trial[NCT00000136]Phase 3234 participants (Actual)Interventional1990-03-31Completed
Studies of the Ocular Complications of AIDS (SOCA) CMV Retinitis Trial: Foscarnet-Ganciclovir Component[NCT00000665]240 participants InterventionalCompleted
A Phase II Randomized Controlled Trial of Immediate Versus Delayed Foscarnet Therapy in AIDS Patients With Non-Immediately Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due to Myelosuppression[NCT00000697]Phase 20 participants (Actual)InterventionalWithdrawn
A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure[NCT00000691]Phase 2156 participants InterventionalCompleted
Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome[NCT00000726]Phase 153 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Mortality

(NCT00000136)
Timeframe: All patients enrolled will be followed until a common study closing date, which was chosen to provide a minimum of 1 year of follow-up for all patients enrolled in the trial.

Interventionparticipants (Number)
Foscarnet107
Ganciclovir127

Reviews

14 reviews available for phosphonoacetic acid and Neuroretinitis

ArticleYear
Characteristics of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Maintenance therapy for cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome: foscarnet.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Combination; Eye Infections, Viral; Fosc

1992
Cytomegalovirus retinitis in AIDS.
    Journal of the American Optometric Association, 1992, Volume: 63, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Diagnosis, Differe

1992
Foscarnet and ganciclovir in the treatment of cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5 Suppl 1

    Topics: Cytomegalovirus Infections; Drug Therapy, Combination; Foscarnet; Ganciclovir; Humans; Phosphonoacet

1992
Foscarnet-induced penile ulcer.
    Journal of the American Academy of Dermatology, 1992, Volume: 27, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Foscarnet;

1992
Treatment and prophylaxis of cytomegalovirus disease.
    Pharmacotherapy, 1992, Volume: 12, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Gancicl

1992
Foscarnet. A review of its antiviral activity, pharmacokinetic properties and therapeutic use in immunocompromised patients with cytomegalovirus retinitis.
    Drugs, 1991, Volume: 41, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Anemia; Animals; Antiviral Agents; Cytomegalovirus; Cytomegalovi

1991
Approaches to the treatment of cytomegalovirus retinitis: ganciclovir and foscarnet.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4 Suppl 1

    Topics: Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Combination; Eye Infections, Viral; Fosc

1991
Diagnosis and treatment of cytomegalovirus retinitis.
    Journal of acquired immune deficiency syndromes, 1991, Volume: 4 Suppl 1

    Topics: Antiviral Agents; Cytomegalovirus Infections; Diagnosis, Differential; Eye Infections, Viral; Foscar

1991
Foscarnet sodium.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1991
Cotton-wool spots and cytomegalovirus retinitis in AIDS.
    International ophthalmology clinics, 1989,Summer, Volume: 29, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Cytomegalovirus Infections; Diabetic Retinopathy; Dia

1989
Cytomegalovirus infection in the acquired immune deficiency syndrome.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23 Suppl E

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Addison Disease; Antiviral Agents; Colitis; Cytomegal

1989
Serious cytomegalovirus disease in the acquired immunodeficiency syndrome (AIDS). Clinical findings, diagnosis, and treatment.
    Annals of internal medicine, 1988, Volume: 108, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cytomegalovirus Infections; Foscarn

1988
The diagnosis of cytomegalovirus retinitis.
    Annals of internal medicine, 1988, Dec-15, Volume: 109, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cytomegalovirus Infections; Diagnos

1988

Trials

8 trials available for phosphonoacetic acid and Neuroretinitis

ArticleYear
The treatment of cytomegalovirus in AIDS--more than meets the eye.
    The New England journal of medicine, 1992, Jan-23, Volume: 326, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Comb

1992
Design of a randomized controlled trial of foscarnet in patients with cytomegalovirus retinitis associated with acquired immunodeficiency syndrome.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Eye Infecti

1992
Studies of ocular complications of AIDS Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial: 1. Rationale, design, and methods. AIDS Clinical Trials Group (ACTG).
    Controlled clinical trials, 1992, Volume: 13, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Infe

1992
Studies of ocular complications of AIDS Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial: 1. Rationale, design, and methods. AIDS Clinical Trials Group (ACTG).
    Controlled clinical trials, 1992, Volume: 13, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Infe

1992
Studies of ocular complications of AIDS Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial: 1. Rationale, design, and methods. AIDS Clinical Trials Group (ACTG).
    Controlled clinical trials, 1992, Volume: 13, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Infe

1992
Studies of ocular complications of AIDS Foscarnet-Ganciclovir Cytomegalovirus Retinitis Trial: 1. Rationale, design, and methods. AIDS Clinical Trials Group (ACTG).
    Controlled clinical trials, 1992, Volume: 13, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Infe

1992
Effect of foscarnet therapy on human immunodeficiency virus p24 antigen levels in AIDS patients with cytomegalovirus retinitis.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Infections; Dose-Response Relationship, D

1992
Foscarnet and Ganciclovir in the treatment of CMV retinitis in AIDS patients: a randomised comparison.
    The Journal of infection, 1992, Volume: 25, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Gancicl

1992
Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis.
    The New England journal of medicine, 1992, 01-23, Volume: 326, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; Cytomegalov

1992
Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis.
    The New England journal of medicine, 1992, 01-23, Volume: 326, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; Cytomegalov

1992
Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis.
    The New England journal of medicine, 1992, 01-23, Volume: 326, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; Cytomegalov

1992
Mortality in patients with the acquired immunodeficiency syndrome treated with either foscarnet or ganciclovir for cytomegalovirus retinitis.
    The New England journal of medicine, 1992, 01-23, Volume: 326, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; CD4-Positive T-Lymphocytes; Cytomegalov

1992
AIDS file.
    The American journal of nursing, 1991, Volume: 91, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Gancicl

1991
A randomized, controlled trial of foscarnet in the treatment of cytomegalovirus retinitis in patients with AIDS.
    Annals of internal medicine, 1991, Nov-01, Volume: 115, Issue:9

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Eye Infecti

1991

Other Studies

40 other studies available for phosphonoacetic acid and Neuroretinitis

ArticleYear
From the National Institutes of Health.
    JAMA, 1992, Jan-08, Volume: 267, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Anti-Inflammatory Agents, Non-Steroidal; Antiviral Agents; Arthr

1992
Foscarnet.
    The Medical letter on drugs and therapeutics, 1992, Jan-10, Volume: 34, Issue:861

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Didanosine and foscarnet marketed for use by patients with AIDS.
    Clinical pharmacy, 1992, Volume: 11, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Didanosine; Foscar

1992
Clinical implications of herpesvirus infections in patients with AIDS. Introduction.
    The American journal of medicine, 1992, Feb-14, Volume: 92, Issue:2A

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Treatment of cytomegalovirus retinitis--1992.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1992, Volume: 110, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Treatment of aggressive cytomegalovirus retinitis with ganciclovir in combination with foscarnet in a child infected with human immunodeficiency virus.
    The Journal of pediatrics, 1992, Volume: 120, Issue:3

    Topics: Antiviral Agents; Child, Preschool; Cytomegalovirus Infections; Drug Therapy, Combination; Female; F

1992
Why was treatment of cytomegalovirus retinitis randomized?
    Annals of internal medicine, 1992, Apr-01, Volume: 116, Issue:7

    Topics: Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Viral; Foscarnet; Ganciclovir; Humans;

1992
Cytomegalovirus and AIDS.
    Genitourinary medicine, 1992, Volume: 68, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Foscarnet;

1992
Treatment of CMV retinitis.
    The New England journal of medicine, 1992, Jun-18, Volume: 326, Issue:25

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Drug Therapy, Comb

1992
Treatment of CMV retinitis.
    The New England journal of medicine, 1992, Jun-18, Volume: 326, Issue:25

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Gancicl

1992
Treatment of CMV retinitis.
    The New England journal of medicine, 1992, Jun-18, Volume: 326, Issue:25

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Gancicl

1992
Foscarnet induction therapy for cytomegalovirus retinitis in AIDS: comparison of twice-daily and three-times-daily regimens.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Drug Admini

1992
Therapeutic algorithm for treatment of cytomegalovirus retinitis in persons with AIDS. A roundtable summary.
    Journal of acquired immune deficiency syndromes, 1992, Volume: 5 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Adult; Algorithms; Cytomegalovirus Infections; Foscarnet; Gancic

1992
Herpes simplex virus infection during foscarnet therapy.
    The Journal of infectious diseases, 1992, Volume: 166, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Foscarnet;

1992
Treatment of CMV retinitis.
    Lancet (London, England), 1992, Jan-25, Volume: 339, Issue:8787

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1992
Foscarnet for CMV retinitis.
    Lancet (London, England), 1992, Feb-22, Volume: 339, Issue:8791

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Gancicl

1992
Foscarnet therapy for ganciclovir-resistant cytomegalovirus retinitis in patients with AIDS.
    The Journal of infectious diseases, 1991, Volume: 163, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus; Cytomegalovirus Infect

1991
Successful foscarnet therapy for cytomegalovirus retinitis in an AIDS patient undergoing hemodialysis: rationale for empiric dosing and plasma level monitoring.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Acute Kidney Injury; Adult; Antiviral Agents; Cytomegalovirus In

1991
National Eye Institute issues clinical alert about CMV retinitis in AIDS.
    JAMA, 1991, Nov-20, Volume: 266, Issue:19

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1991
Foscarnet approved for cytomegalovirus retinitis.
    American family physician, 1991, Volume: 44, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Humans;

1991
From the Food and Drug Administration.
    JAMA, 1991, Dec-18, Volume: 266, Issue:23

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Eye Infections, Vi

1991
Cytomegalovirus infection in AIDS. Patterns of disease, response to therapy and trends in survival.
    The Journal of infection, 1991, Volume: 23, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Colitis; Cytomegalovirus Infections; Female; F

1991
Survival of patients with AIDS and cytomegalovirus disease treated with ganciclovir or foscarnet.
    AIDS (London, England), 1991, Volume: 5, Issue:8

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Female; Fos

1991
Early virus isolation, early structural antigen detection and DNA amplification by the polymerase chain reaction in polymorphonuclear leukocytes from AIDS patients with human cytomegalovirus viraemia.
    Molecular and cellular probes, 1991, Volume: 5, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Viral; Antiviral Agents; Cytomegalovirus; Cytomegalovi

1991
Simultaneous treatment of cytomegalovirus retinitis with ganciclovir and foscarnet.
    Lancet (London, England), 1991, Jul-27, Volume: 338, Issue:8761

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Eye Infecti

1991
Treatment of cytomegalovirus retinitis with ganciclovir and foscarnet.
    Lancet (London, England), 1991, Aug-31, Volume: 338, Issue:8766

    Topics: Adult; Cytomegalovirus Infections; Drug Combinations; Foscarnet; Ganciclovir; HIV Seropositivity; Hu

1991
Seeing the way forward for treatment of CMV retinitis.
    Lancet (London, England), 1991, Dec-14, Volume: 338, Issue:8781

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Cytomegalovirus Infe

1991
CMV retinitis and the use of FK 506.
    Transplantation proceedings, 1991, Volume: 23, Issue:6

    Topics: Acyclovir; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Humans; Immunosuppression Therap

1991
Foscarnet therapy of cytomegalovirus retinitis in AIDS.
    Journal of acquired immune deficiency syndromes, 1990, Volume: 3, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Humans;

1990
Nephrogenic diabetes insipidus associated with foscarnet treatment of cytomegalovirus retinitis.
    Annals of internal medicine, 1990, Jun-15, Volume: 112, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Diabetes In

1990
Foscarnet in the treatment of cytomegalovirus retinitis in acquired immune deficiency syndrome.
    Ophthalmology, 1989, Volume: 96, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Creatine; Cytomegalovirus Infections; Drug Therapy, Combi

1989
Foscarnet treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Calcium; Cytomegalovirus Infections; Fo

1989
Pharmacokinetics of intermittently administered intravenous foscarnet in the treatment of acquired immunodeficiency syndrome patients with serious cytomegalovirus retinitis.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Foscarnet;

1989
Foscarnet infusion at home.
    Lancet (London, England), 1989, Jan-21, Volume: 1, Issue:8630

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Drug Admini

1989
Treatment of CMV retinitis in an AIDS patient.
    The British journal of ophthalmology, 1987, Volume: 71, Issue:11

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cytomegalovirus Infections; Foscarn

1987
Treatment of cytomegalovirus retinitis with trisodium phosphonoformate hexahydrate (Foscarnet).
    The Journal of infectious diseases, 1988, Volume: 157, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antiviral Agents; Cytomegalovirus Infections; Foscarnet;

1988
Effect of Foscarnet therapy on infection with human immunodeficiency virus in patients with AIDS.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; HIV; HI

1988
Foscarnet as treatment for cytomegalovirus retinitis following bone marrow transplantation.
    Postgraduate medical journal, 1988, Volume: 64, Issue:751

    Topics: Adult; Antiviral Agents; Bone Marrow Transplantation; Busulfan; Cataract; Cytomegalovirus Infections

1988
Foscarnet infusion at home.
    Lancet (London, England), 1988, Dec-03, Volume: 2, Issue:8623

    Topics: Acquired Immunodeficiency Syndrome; Adult; Cytomegalovirus Infections; Foscarnet; HIV Antigens; Home

1988
Foscarnet for cytomegalovirus retinitis.
    Annals of internal medicine, 1985, Volume: 103, Issue:6 ( Pt 1)

    Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cytomegalovirus Infections; Foscarnet; Humans;

1985