Page last updated: 2024-10-17

phosphonoacetic acid and Leukemia

phosphonoacetic acid has been researched along with Leukemia in 4 studies

Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.

Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

Research Excerpts

ExcerptRelevanceReference
"Intravenous foscarnet was given on an emergency basis to 30 immunosuppressed patients with cytomegalovirus (CMV) disease, of whom 28 were organ transplant recipients."9.06Sensitivity of cytomegalovirus to intravenous foscarnet treatment. ( Akesson-Johansson, A; Lernestedt, JO; Lönnqvist, B; Ringdén, O; Wahren, B, 1986)
"Intravenous foscarnet was given on an emergency basis to 30 immunosuppressed patients with cytomegalovirus (CMV) disease, of whom 28 were organ transplant recipients."5.06Sensitivity of cytomegalovirus to intravenous foscarnet treatment. ( Akesson-Johansson, A; Lernestedt, JO; Lönnqvist, B; Ringdén, O; Wahren, B, 1986)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leyva, A1
Appel, H1
Smith, P1
Lankelma, J1
Pinedo, HM1
Noordhuis, P1
Kazemier, KM1
Kasperrs, GJ1
Peters, GJ1
Akesson-Johansson, A1
Lernestedt, JO1
Ringdén, O1
Lönnqvist, B1
Wahren, B1
O'Dwyer, PJ1
King, SA1
Hoth, DF1
Leyland-Jones, B1

Reviews

1 review available for phosphonoacetic acid and Leukemia

ArticleYear
Role of thymidine in biochemical modulation: a review.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic A

1987

Trials

1 trial available for phosphonoacetic acid and Leukemia

ArticleYear
Sensitivity of cytomegalovirus to intravenous foscarnet treatment.
    Bone marrow transplantation, 1986, Volume: 1, Issue:2

    Topics: Antiviral Agents; Bone Marrow Transplantation; Cytomegalovirus; Cytomegalovirus Infections; Female;

1986

Other Studies

2 other studies available for phosphonoacetic acid and Leukemia

ArticleYear
Inhibition of cell growth by N-(phosphonacetyl)-L-aspartate in human and murine cells in vitro.
    Cancer letters, 1981, Volume: 12, Issue:1-2

    Topics: Animals; Antineoplastic Agents; Aspartate Carbamoyltransferase; Aspartic Acid; Cell Division; Cell L

1981
Modulation of metabolism and cytotoxicity of cytosine arabinoside with N-(phosphon)-acetyl-L-aspartate in human leukemic blast cells and cell lines.
    Leukemia research, 1996, Volume: 20, Issue:2

    Topics: Antimetabolites, Antineoplastic; Arabinofuranosylcytosine Triphosphate; Aspartic Acid; Cytarabine; C

1996