phosphonoacetic acid has been researched along with Leukemia P388 in 3 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tiazofurin is a synthetic "C" nucleoside analogue with a promising spectrum of experimental antitumor activity and a relatively novel mechanism of action." | 1.27 | Therapeutic synergism of tiazofurin and selected antitumor drugs against sensitive and resistant P388 leukemia in mice. ( Harrison, SD; O'Dwyer, PJ; Trader, MW, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ardalan, B | 1 |
| Jayaram, HN | 1 |
| Johnson, RK | 1 |
| Vaghefi, MM | 1 |
| McKernan, PA | 1 |
| Robins, RK | 1 |
| Harrison, SD | 1 |
| O'Dwyer, PJ | 1 |
| Trader, MW | 1 |
3 other studies available for phosphonoacetic acid and Leukemia P388
| Article | Year |
|---|---|
Collateral sensitivity to N-(phosphonacetyl)-L-aspartic acid in a line of P388 leukemia cells selected for resistance to L-(alpha S, 5S)-alpha-amino-3- chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
Topics: Adenine Phosphoribosyltransferase; Animals; Antibiotics, Antineoplastic; Antimetabolites, Antineopla | 1983 |
Synthesis and antiviral activity of certain nucleoside 5'-phosphonoformate derivatives.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Deltaretrovirus; Foscarnet; Hydrogen-Ion | 1986 |
Therapeutic synergism of tiazofurin and selected antitumor drugs against sensitive and resistant P388 leukemia in mice.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cispl | 1986 |