Page last updated: 2024-10-17

phosphonoacetic acid and Hypocalcemia

phosphonoacetic acid has been researched along with Hypocalcemia in 3 studies

Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.

Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"Foscarnet (trisodium phosphonoformate), an investigational pyrophosphate analog increasingly used to treat refractory cytomegalovirus retinitis and mucocutaneous herpes simplex virus infections in immunocompromised patients, has been reported to cause abnormalities in serum calcium and phosphate, including cases of fatal hypocalcemia."7.68Foscarnet-induced hypocalcemia and effects of foscarnet on calcium metabolism. ( Aweeka, FT; Causey, DM; Gambertoglio, JG; Jacobson, MA; Portale, AA, 1991)
"Foscarnet (Foscavir) is an antiviral drug for intravenous (i."5.28Hypocalcemia induced by foscarnet (Foscavir) infusion in dogs. ( Lundström, J; Nordgren, T; Ryrfeldt, A, 1992)
"Foscarnet (trisodium phosphonoformate), an investigational pyrophosphate analog increasingly used to treat refractory cytomegalovirus retinitis and mucocutaneous herpes simplex virus infections in immunocompromised patients, has been reported to cause abnormalities in serum calcium and phosphate, including cases of fatal hypocalcemia."3.68Foscarnet-induced hypocalcemia and effects of foscarnet on calcium metabolism. ( Aweeka, FT; Causey, DM; Gambertoglio, JG; Jacobson, MA; Portale, AA, 1991)
"Foscarnet (Foscavir) is an antiviral drug for intravenous (i."1.28Hypocalcemia induced by foscarnet (Foscavir) infusion in dogs. ( Lundström, J; Nordgren, T; Ryrfeldt, A, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ryrfeldt, A1
Nordgren, T1
Lundström, J1
Jacobson, MA1
Gambertoglio, JG1
Aweeka, FT1
Causey, DM1
Portale, AA1
Youle, MS1
Clarbour, J1
Gazzard, B1
Chanas, A1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure[NCT00000691]Phase 2156 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for phosphonoacetic acid and Hypocalcemia

ArticleYear
Hypocalcemia induced by foscarnet (Foscavir) infusion in dogs.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:1

    Topics: Animals; Blood Cell Count; Calcitriol; Dogs; Foscarnet; Homeostasis; Hypocalcemia; Infusions, Intrav

1992
Foscarnet-induced hypocalcemia and effects of foscarnet on calcium metabolism.
    The Journal of clinical endocrinology and metabolism, 1991, Volume: 72, Issue:5

    Topics: Antiviral Agents; Calcium; Dose-Response Relationship, Drug; Foscarnet; Herpes Simplex; Humans; Hypo

1991
Severe hypocalcaemia in AIDS patients treated with foscarnet and pentamidine.
    Lancet (London, England), 1988, Jun-25, Volume: 1, Issue:8600

    Topics: Acquired Immunodeficiency Syndrome; Amidines; Foscarnet; Humans; Hypocalcemia; Organophosphorus Comp

1988