phosphonoacetic acid has been researched along with Glial Cell Tumors in 3 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate an intracranial polymer implant containing bromodeoxyuridine (BrdUrd) and N-(phosphonacetyl)-L-aspartic acid (PALA) in combination with external beam radiotherapy (EBRT) in the treatment of a rat glioma." | 3.72 | Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy. ( Lehnert, S; Li, Y; Owusu, A, 2004) |
| "Malignant gliomas are the most common malignant brain tumors and are almost always fatal." | 1.28 | Experimental therapy of human glioma by means of a genetically engineered virus mutant. ( Coen, DM; Malick, A; Markert, JM; Martuza, RL; Ruffner, KL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Owusu, A | 1 |
| Lehnert, S | 1 |
| Johnson, RK | 1 |
| Swyryd, EA | 1 |
| Stark, GR | 1 |
| Martuza, RL | 1 |
| Malick, A | 1 |
| Markert, JM | 1 |
| Ruffner, KL | 1 |
| Coen, DM | 1 |
3 other studies available for phosphonoacetic acid and Glial Cell Tumors
| Article | Year |
|---|---|
Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain Neoplasms; Bromodeoxyu | 2004 |
Effects of N-(phosphonacetyl)-L-aspartate on murine tumors and normal tissues in vivo and in vitro and the relationship of sensitivity to rate of proliferation and level of aspartate transcarbamylase.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; Cells, Cult | 1978 |
Experimental therapy of human glioma by means of a genetically engineered virus mutant.
Topics: Animals; Antiviral Agents; Brain Neoplasms; Cells, Cultured; Dose-Response Relationship, Drug; Fosca | 1991 |