phosphonoacetic acid has been researched along with Cell Transformation, Neoplastic in 20 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyclin D1 is a key regulator of the G1-S transition in cell cycle, and its gene is amplified and overexpressed in many cancers." | 1.29 | Tumorigenicity and gene amplification potentials of cyclin D1-overexpressing NIH3T3 cells. ( Asano, K; Kakizoe, T; Machida, T; Ochiya, T; Ohishi, Y; Sakamoto, H; Sasaki, H; Sugimura, T; Terada, M; Yoshida, T, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (35.00) | 18.7374 |
| 1990's | 10 (50.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 1 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, Y | 1 |
| Cai, S | 2 |
| Yang, L | 1 |
| Yu, S | 1 |
| Jiang, J | 1 |
| Yan, X | 1 |
| Zhang, H | 1 |
| Liu, L | 1 |
| Liu, Q | 1 |
| Du, J | 1 |
| Sung, KL | 1 |
| Dini, G | 1 |
| Funghini, S | 1 |
| Witort, E | 1 |
| Magnelli, L | 1 |
| Fanti, E | 1 |
| Rifkin, DB | 1 |
| Del Rosso, M | 1 |
| Field, HJ | 1 |
| Darby, G | 1 |
| Wildy, P | 1 |
| Moro, F | 1 |
| Ottaggio, L | 1 |
| Bonatti, S | 1 |
| Simili, M | 1 |
| Miele, M | 1 |
| Bozzo, S | 1 |
| Abbondandolo, A | 1 |
| Vatteroni, L | 1 |
| Piras, A | 1 |
| Mariani, T | 1 |
| Caligo, MA | 1 |
| Rainaldi, G | 1 |
| Wani, MA | 1 |
| Xu, X | 1 |
| Stambrook, PJ | 1 |
| Jonczyk, P | 1 |
| White, A | 2 |
| Lum, K | 1 |
| Barrett, JC | 1 |
| Tlsty, TD | 3 |
| Asano, K | 1 |
| Sakamoto, H | 1 |
| Sasaki, H | 1 |
| Ochiya, T | 1 |
| Yoshida, T | 1 |
| Ohishi, Y | 1 |
| Machida, T | 1 |
| Kakizoe, T | 1 |
| Sugimura, T | 1 |
| Terada, M | 1 |
| Jiang, XR | 1 |
| Jimenez, G | 1 |
| Chang, E | 1 |
| Frolkis, M | 1 |
| Kusler, B | 1 |
| Sage, M | 1 |
| Beeche, M | 1 |
| Bodnar, AG | 1 |
| Wahl, GM | 1 |
| Chiu, CP | 1 |
| Melnyk, S | 1 |
| Pogribna, M | 1 |
| Miller, BJ | 1 |
| Basnakian, AG | 1 |
| Pogribny, IP | 1 |
| James, SJ | 1 |
| Piao, CQ | 2 |
| Hei, TK | 2 |
| Wu, LJ | 1 |
| Willey, JC | 1 |
| Hall, EJ | 1 |
| Rickinson, AB | 3 |
| Finerty, S | 2 |
| Epstein, MA | 3 |
| Thorley-Lawson, DA | 1 |
| Strominger, JL | 1 |
| Goodman, SR | 1 |
| Prezyna, C | 1 |
| Clough, W | 1 |
| Sanchez, J | 1 |
| Kinsella, AR | 1 |
| Haran, MS | 1 |
| Swyryd, EA | 1 |
| Seaver, SS | 1 |
| Stark, GR | 1 |
20 other studies available for phosphonoacetic acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Targeting eradication of malignant cells derived from human bone marrow mesenchymal stromal cells.
Topics: 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Animals; Antigens, CD; Antimetabolites; A | 2010 |
Overexpression of the 18 kDa and 22/24 kDa FGF-2 isoforms results in differential drug resistance and amplification potential.
Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic Acid; | 2002 |
Isolation and characterization of acyclovir-resistant mutants of herpes simplex virus.
Topics: Acyclovir; Animals; Cell Line; Cell Transformation, Neoplastic; Drug Resistance; Enzyme Induction; G | 1980 |
p53 expression in normal versus transformed mammalian cells.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; Aspartic Acid; Burkitt Lymphoma; Cell Line; | 1995 |
Accumulation of anchorage independent cells showing amplified genes (CAD) during the in vitro propagation of CHEF18 Chinese hamster cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydr | 1993 |
Increased methotrexate resistance and dhfr gene amplification as a consequence of induced Ha-ras expression in NIH 3T3 cells.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Aspartic Acid; Cell Transformation, Neoplastic; Drug Resi | 1994 |
Amplification potential in preneoplastic and neoplastic Syrian hamster embryo fibroblasts transformed by various carcinogens.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Carcinogens; Cell Transformation, Neoplastic; Cell Tr | 1993 |
Tumorigenicity and gene amplification potentials of cyclin D1-overexpressing NIH3T3 cells.
Topics: 3T3 Cells; Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glu | 1995 |
Telomerase expression in human somatic cells does not induce changes associated with a transformed phenotype.
Topics: Aspartic Acid; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cyclin-Dependent | 1999 |
Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells.
Topics: Animals; Aspartic Acid; Cell Death; Cell Division; Cell Transformation, Neoplastic; CHO Cells; Crice | 1999 |
Gene amplification and microsatellite instability induced in tumorigenic human bronchial epithelial cells by alpha particles and heavy ions.
Topics: Alpha Particles; Animals; Antimetabolites, Antineoplastic; Aspartate Carbamoyltransferase; Aspartic | 2001 |
Genomic instability and tumorigenic induction in immortalized human bronchial epithelial cells by heavy ions.
Topics: Alpha Particles; Animals; Antineoplastic Agents; Aspartic Acid; Bronchi; Cell Fusion; Cell Line, Tra | 1998 |
Mechanism of the establishment of Epstein-Barr virus genome-containing lymphoid cell lines from infectious mononucleosis patients: studies with phosphonoacetate.
Topics: Antigens, Viral; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cult | 1977 |
Reversible inhibition by phosphonoacetic acid of human B lymphocyte transformation by Epstein-Barr virus.
Topics: B-Lymphocytes; Cell Transformation, Neoplastic; Cell Transformation, Viral; DNA; Herpesvirus 4, Huma | 1978 |
Sensitivity of the transforming and replicative functions of Epstein--Barr virus to inhibition by phosphonoacetate.
Topics: Antigens, Viral; Capsid; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Dos | 1978 |
Identification and partial purification of two EBV-associated DNA polymerases.
Topics: Cell Line; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; DNA-Directed DNA Polymer | 1978 |
Inhibition by phosphonoacetate of the in vitro outgrowth of Epstein-Barr virus genome-containing cell lines from the blood of infectious mononucleosis patients.
Topics: Cell Division; Cell Line; Cell Transformation, Neoplastic; Herpesvirus 4, Human; Humans; Infectious | 1978 |
Suppression of gene amplification in human cell hybrids.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Cell Line; Cell Transformation, Neoplastic; Drug Resi | 1992 |
Decreasing sensitivity to cytotoxic agents parallels increasing tumorigenicity in human fibroblasts.
Topics: Aspartic Acid; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Resistance; | 1991 |
N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Bicarbonates; Carbamates; Carbon Radioisotop | 1974 |