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phosphonoacetic acid and Brain Diseases

phosphonoacetic acid has been researched along with Brain Diseases in 3 studies

Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
"Reversible encephalopathy was observed in 6 (7."1.26Neurotoxicity of the pyrimidine synthesis inhibitor N-phosphonoacetyl-L-aspartate. ( Casper, ES; Gralla, RJ; Kemeny, N; Wiley, RG, 1982)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wiley, RG1
Gralla, RJ2
Casper, ES2
Kemeny, N1
Natale, RB1
Yagoda, A1
Young, CW1
Streissle, G1

Other Studies

3 other studies available for phosphonoacetic acid and Brain Diseases

ArticleYear
Neurotoxicity of the pyrimidine synthesis inhibitor N-phosphonoacetyl-L-aspartate.
    Annals of neurology, 1982, Volume: 12, Issue:2

    Topics: Adult; Aged; Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Brain Diseases; Disease Models

1982
Phase I trial of PALA.
    Cancer treatment reports, 1980, Volume: 64, Issue:12

    Topics: Antineoplastic Agents; Aspartic Acid; Brain Diseases; Diarrhea; Dose-Response Relationship, Drug; Ga

1980
Comparative evaluation of antiherpetic drugs in animal experiments.
    Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie, 1979, Volume: 38

    Topics: Animals; Brain Diseases; Disease Models, Animal; Evaluation Studies as Topic; Herpes Simplex; Immuno

1979