phosphonoacetic acid has been researched along with Benign Neoplasms, Brain in 6 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate an intracranial polymer implant containing bromodeoxyuridine (BrdUrd) and N-(phosphonacetyl)-L-aspartic acid (PALA) in combination with external beam radiotherapy (EBRT) in the treatment of a rat glioma." | 3.72 | Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy. ( Lehnert, S; Li, Y; Owusu, A, 2004) |
| "Malignant gliomas are the most common malignant brain tumors and are almost always fatal." | 1.28 | Experimental therapy of human glioma by means of a genetically engineered virus mutant. ( Coen, DM; Malick, A; Markert, JM; Martuza, RL; Ruffner, KL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, J | 1 |
| Yin, H | 1 |
| Panandikar, A | 1 |
| Gandhi, V | 1 |
| Sen, S | 1 |
| Muller, FL | 1 |
| Colla, S | 1 |
| Aquilanti, E | 1 |
| Manzo, VE | 1 |
| Genovese, G | 1 |
| Lee, J | 1 |
| Eisenson, D | 1 |
| Narurkar, R | 1 |
| Deng, P | 1 |
| Nezi, L | 1 |
| Lee, MA | 1 |
| Hu, B | 1 |
| Hu, J | 1 |
| Sahin, E | 1 |
| Ong, D | 1 |
| Fletcher-Sananikone, E | 1 |
| Ho, D | 1 |
| Kwong, L | 1 |
| Brennan, C | 1 |
| Wang, YA | 1 |
| Chin, L | 1 |
| DePinho, RA | 1 |
| Li, Y | 1 |
| Owusu, A | 1 |
| Lehnert, S | 1 |
| Stewart, DJ | 1 |
| Leavens, M | 1 |
| Friedman, J | 1 |
| Benjamin, RS | 1 |
| Moore, EC | 1 |
| Bodey, GP | 1 |
| Valdivieso, M | 1 |
| Burgess, MA | 1 |
| Wiseman, C | 1 |
| Loo, TL | 1 |
| Martuza, RL | 1 |
| Malick, A | 1 |
| Markert, JM | 1 |
| Ruffner, KL | 1 |
| Coen, DM | 1 |
| Madani, S | 1 |
| Baillon, J | 1 |
| Fries, J | 1 |
| Belhadj, O | 1 |
| Bettaieb, A | 1 |
| Ben Hamida, M | 1 |
| Hervé, G | 1 |
6 other studies available for phosphonoacetic acid and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Elevated cyclin A associated kinase activity promotes sensitivity of metastatic human cancer cells to DNA antimetabolite drug.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Aspartic Acid; Brain Neoplasms; Cell Line, Tumo | 2015 |
Passenger deletions generate therapeutic vulnerabilities in cancer.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Cell Prolifera | 2012 |
Treatment of intracranial rat glioma model with implant of radiosensitizer and biomodulator drug combined with external beam radiotherapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Brain Neoplasms; Bromodeoxyu | 2004 |
Penetration of N-(phosphonacetyl)-L-aspartate into human central nervous system and intracerebral tumor.
Topics: Aspartic Acid; Brain Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infus | 1980 |
Experimental therapy of human glioma by means of a genetically engineered virus mutant.
Topics: Animals; Antiviral Agents; Brain Neoplasms; Cells, Cultured; Dose-Response Relationship, Drug; Fosca | 1991 |
Pyrimidine pathways enzymes in human tumors of brain and associated tissues: potentialities for the therapeutic use of N-(phosphonacetyl-L-aspartate and 1-beta-D-arabinofuranosylcytosine.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Brain; Brain Neoplasms; Cytarabine; Cytidine Deaminas | 1987 |