phosphonoacetic acid has been researched along with Abnormalities, Autosome in 10 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In cells with multiple chromosomal aberrations and rearranged copies of chromosome 2, amplification of CAD as tandem arrays from rearranged chromosomes is the most frequent mechanism of PALA resistance." | 1.30 | Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged. ( Agarwal, A; Agarwal, ML; Chernova, OB; Davidson, JN; Duncan, P; Groves, RP; MartÃnez, JL; Patterson, TE; Smith, KA; Stark, GR; Stark, MB; Trent, JM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mondello, C | 1 |
| Guasconi, V | 1 |
| Giulotto, E | 1 |
| Nuzzo, F | 1 |
| Mathew, R | 1 |
| Kongara, S | 1 |
| Beaudoin, B | 1 |
| Karp, CM | 1 |
| Bray, K | 1 |
| Degenhardt, K | 1 |
| Chen, G | 1 |
| Jin, S | 1 |
| White, E | 1 |
| Wahl, GM | 2 |
| Vitto, L | 1 |
| Padgett, RA | 1 |
| Stark, GR | 2 |
| Di Leonardo, A | 3 |
| Cavolina, P | 2 |
| Maddalena, A | 1 |
| Tlsty, TD | 2 |
| Jonczyk, P | 1 |
| White, A | 1 |
| Sage, M | 1 |
| Hall, I | 1 |
| Schaefer, D | 1 |
| Briot, A | 1 |
| Livanos, E | 1 |
| Roelofs, H | 1 |
| Poulose, B | 1 |
| Schaefer, DI | 1 |
| Livanos, EM | 1 |
| White, AE | 1 |
| Linke, SP | 1 |
| Clarkin, KC | 1 |
| Tsou, A | 1 |
| Smith, KA | 1 |
| Chernova, OB | 1 |
| Groves, RP | 1 |
| Stark, MB | 1 |
| MartÃnez, JL | 1 |
| Davidson, JN | 1 |
| Trent, JM | 1 |
| Patterson, TE | 1 |
| Agarwal, A | 1 |
| Duncan, P | 1 |
| Agarwal, ML | 1 |
| Soulie, P | 1 |
| Poupon, MF | 1 |
| Remvikos, Y | 1 |
| Dutrillaux, B | 1 |
| Muleris, M | 1 |
| Ottaggio, L | 1 |
| Agnese, C | 1 |
| Bonatti, S | 1 |
| De Ambrosis, A | 1 |
| Degan, P | 1 |
| Miele, M | 1 |
| Randazzo, R | 1 |
| Abbondandolo, A | 1 |
10 other studies available for phosphonoacetic acid and Abnormalities, Autosome
| Article | Year |
|---|---|
Gamma-ray and hydrogen peroxide induction of gene amplification in hamster cells deficient in DNA double strand break repair.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Cell Line; Chromosome Aberrations; Cricetin | 2002 |
Autophagy suppresses tumor progression by limiting chromosomal instability.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartic Acid; Autophagy; Autophagy-Related Prote | 2007 |
Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization.
Topics: Animals; Aspartic Acid; Cells, Cultured; Chromosome Aberrations; Chromosome Mapping; Cricetinae; Dex | 1982 |
DNA topoisomerase II inhibition and gene amplification in V79/B7 cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Benzamides; Carbamoyl-Phosphate Synthase (Gl | 1993 |
Loss of chromosomal integrity in neoplasia.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydr | 1993 |
Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts.
Topics: Aneuploidy; Antineoplastic Agents; Aspartic Acid; Cell Cycle; Cell Division; Cell Line; Cell Transfo | 1993 |
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
Topics: Adenosine Monophosphate; Amides; Antimetabolites, Antineoplastic; Aspartic Acid; Cell Cycle; Cells, | 1996 |
Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); | 1997 |
Distinct chromosomal alterations associated with TP53 status of LoVo cells under PALA selective pressure: a parallel with cytogenetic pathways of colorectal cancers.
Topics: Aspartic Acid; Chromosome Aberrations; Colorectal Neoplasms; Drug Resistance; Enzyme Inhibitors; Gen | 1999 |
Chromosome aberrations associated with CAD gene amplification in Chinese hamster cultured cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydr | 1988 |