phosphonoacetic acid has been researched along with Abnormalities, Autosome in 10 studies
Phosphonoacetic Acid: A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
phosphonoacetic acid : A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group.
Excerpt | Relevance | Reference |
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"In cells with multiple chromosomal aberrations and rearranged copies of chromosome 2, amplification of CAD as tandem arrays from rearranged chromosomes is the most frequent mechanism of PALA resistance." | 1.30 | Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged. ( Agarwal, A; Agarwal, ML; Chernova, OB; Davidson, JN; Duncan, P; Groves, RP; MartÃnez, JL; Patterson, TE; Smith, KA; Stark, GR; Stark, MB; Trent, JM, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (20.00) | 18.7374 |
1990's | 6 (60.00) | 18.2507 |
2000's | 2 (20.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Mondello, C | 1 |
Guasconi, V | 1 |
Giulotto, E | 1 |
Nuzzo, F | 1 |
Mathew, R | 1 |
Kongara, S | 1 |
Beaudoin, B | 1 |
Karp, CM | 1 |
Bray, K | 1 |
Degenhardt, K | 1 |
Chen, G | 1 |
Jin, S | 1 |
White, E | 1 |
Wahl, GM | 2 |
Vitto, L | 1 |
Padgett, RA | 1 |
Stark, GR | 2 |
Di Leonardo, A | 3 |
Cavolina, P | 2 |
Maddalena, A | 1 |
Tlsty, TD | 2 |
Jonczyk, P | 1 |
White, A | 1 |
Sage, M | 1 |
Hall, I | 1 |
Schaefer, D | 1 |
Briot, A | 1 |
Livanos, E | 1 |
Roelofs, H | 1 |
Poulose, B | 1 |
Schaefer, DI | 1 |
Livanos, EM | 1 |
White, AE | 1 |
Linke, SP | 1 |
Clarkin, KC | 1 |
Tsou, A | 1 |
Smith, KA | 1 |
Chernova, OB | 1 |
Groves, RP | 1 |
Stark, MB | 1 |
MartÃnez, JL | 1 |
Davidson, JN | 1 |
Trent, JM | 1 |
Patterson, TE | 1 |
Agarwal, A | 1 |
Duncan, P | 1 |
Agarwal, ML | 1 |
Soulie, P | 1 |
Poupon, MF | 1 |
Remvikos, Y | 1 |
Dutrillaux, B | 1 |
Muleris, M | 1 |
Ottaggio, L | 1 |
Agnese, C | 1 |
Bonatti, S | 1 |
De Ambrosis, A | 1 |
Degan, P | 1 |
Miele, M | 1 |
Randazzo, R | 1 |
Abbondandolo, A | 1 |
10 other studies available for phosphonoacetic acid and Abnormalities, Autosome
Article | Year |
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Gamma-ray and hydrogen peroxide induction of gene amplification in hamster cells deficient in DNA double strand break repair.
Topics: Animals; Antimetabolites, Antineoplastic; Aspartic Acid; Cell Line; Chromosome Aberrations; Cricetin | 2002 |
Autophagy suppresses tumor progression by limiting chromosomal instability.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartic Acid; Autophagy; Autophagy-Related Prote | 2007 |
Single-copy and amplified CAD genes in Syrian hamster chromosomes localized by a highly sensitive method for in situ hybridization.
Topics: Animals; Aspartic Acid; Cells, Cultured; Chromosome Aberrations; Chromosome Mapping; Cricetinae; Dex | 1982 |
DNA topoisomerase II inhibition and gene amplification in V79/B7 cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Benzamides; Carbamoyl-Phosphate Synthase (Gl | 1993 |
Loss of chromosomal integrity in neoplasia.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydr | 1993 |
Multiple mechanisms of N-(phosphonoacetyl)-L-aspartate drug resistance in SV40-infected precrisis human fibroblasts.
Topics: Aneuploidy; Antineoplastic Agents; Aspartic Acid; Cell Cycle; Cell Division; Cell Line; Cell Transfo | 1993 |
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
Topics: Adenosine Monophosphate; Amides; Antimetabolites, Antineoplastic; Aspartic Acid; Cell Cycle; Cells, | 1996 |
Multiple mechanisms of N-phosphonacetyl-L-aspartate resistance in human cell lines: carbamyl-P synthetase/aspartate transcarbamylase/dihydro-orotase gene amplification is frequent only when chromosome 2 is rearranged.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); | 1997 |
Distinct chromosomal alterations associated with TP53 status of LoVo cells under PALA selective pressure: a parallel with cytogenetic pathways of colorectal cancers.
Topics: Aspartic Acid; Chromosome Aberrations; Colorectal Neoplasms; Drug Resistance; Enzyme Inhibitors; Gen | 1999 |
Chromosome aberrations associated with CAD gene amplification in Chinese hamster cultured cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamoyl-Phosphate Synthase (Glutamine-Hydr | 1988 |