phosphoenolpyruvate has been researched along with Melanoma in 3 studies
Phosphoenolpyruvate: A monocarboxylic acid anion derived from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. It is a metabolic intermediate in GLYCOLYSIS; GLUCONEOGENESIS; and other pathways.
phosphoenolpyruvate : A monocarboxylic acid anion resuting from selective deprotonation of the carboxy group of phosphoenolpyruvic acid.
phosphoenolpyruvic acid : A monocarboxylic acid that is acrylic acid substituted by a phosphonooxy group at position 2. It is a metabolic intermediate in pathways like glycolysis and gluconeogenesis.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is thought that cancer cells engage in Warburg metabolism to meet intrinsic biosynthetic requirements of cell growth and proliferation." | 1.42 | Nutrient Competition: A New Axis of Tumor Immunosuppression. ( Restifo, NP; Roychoudhuri, R; Sukumar, M, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ren, M | 1 |
| Wang, L | 1 |
| Gao, ZX | 1 |
| Deng, XY | 1 |
| Shen, KJ | 1 |
| Li, YL | 1 |
| Ding, YT | 1 |
| Wei, CY | 1 |
| Gu, JY | 1 |
| Ho, PC | 1 |
| Bihuniak, JD | 1 |
| Macintyre, AN | 1 |
| Staron, M | 1 |
| Liu, X | 1 |
| Amezquita, R | 1 |
| Tsui, YC | 1 |
| Cui, G | 1 |
| Micevic, G | 1 |
| Perales, JC | 1 |
| Kleinstein, SH | 1 |
| Abel, ED | 1 |
| Insogna, KL | 1 |
| Feske, S | 1 |
| Locasale, JW | 1 |
| Bosenberg, MW | 1 |
| Rathmell, JC | 1 |
| Kaech, SM | 1 |
| Sukumar, M | 1 |
| Roychoudhuri, R | 1 |
| Restifo, NP | 1 |
3 other studies available for phosphoenolpyruvate and Melanoma
| Article | Year |
|---|---|
Overcoming chemoresistance to b-raf inhibitor in melanoma via targeted inhibition of phosphoenolpyruvate carboxykinase1 using 3-mercaptopropionic acid.
Topics: 3-Mercaptopropionic Acid; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Indoles; Melanoma; Ph | 2022 |
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.
Topics: Animals; Calcium; CD4-Positive T-Lymphocytes; Endoplasmic Reticulum; Glycolysis; Hexokinase; Immunot | 2015 |
Nutrient Competition: A New Axis of Tumor Immunosuppression.
Topics: Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Glycolysis; Lymphocytes, Tumor-Infi | 2015 |