Page last updated: 2024-09-03

phosphocitrate and Osteoarthritis

phosphocitrate has been researched along with Osteoarthritis in 9 studies

*Osteoarthritis: A progressive, degenerative joint disease, the most common form of arthritis, especially in older persons. The disease is thought to result not from the aging process but from biochemical changes and biomechanical stresses affecting articular cartilage. In the foreign literature it is often called osteoarthrosis deformans. [MeSH]

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (33.33)	29.6817
2010's	6 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cox, M; Hanley, EN; Mauerhan, DR; Roberts, A; Sun, Y	1
Franklin, AM; Gruber, HE; Hanley, EN; Mauerhan, DR; Norton, J; Sun, Y	1
Hanley, EN; Mauerhan, DR; Norton, HJ; Roberts, A; Sun, AR; Sun, Y	1
Hanley, EN; Ingram, J; Kneisl, JS; Mauerhan, DR; Steuerwald, NM; Sun, Y	1
Cox, M; Haines, N; Hanley, EN; Ingram, J; Mauerhan, DR; Mihalko, KL; Roberts, A; Ruffolo, M; Sun, Y	1
Agarwal, S; Das, SK; Srivastava, R	1
McCarthy, GM; O'Shea, FD	1
Cheung, HS; Demadis, KD; Reuben, P; Sallis, JD; Sun, Y; Wenger, L	1
McCarthy, G	1

Reviews

1 review(s) available for phosphocitrate and Osteoarthritis

Article	Year
Basic calcium phosphate deposition in the joint: a potential therapeutic target in osteoarthritis. Current opinion in rheumatology, 2004, Volume: 16, Issue:3 Topics: Arteriosclerosis; Biological Factors; Calcium Phosphates; Cartilage, Articular; Citrates; Crystallization; Humans; Metabolic Diseases; Neoplasms; Osteoarthritis	2004

Other Studies

8 other study(ies) available for phosphocitrate and Osteoarthritis

Article	Year
Biological effects and osteoarthritic disease-modifying activity of small molecule CM-01. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2018, Volume: 36, Issue:1 Topics: Animals; Calcification, Physiologic; Cartilage, Articular; Chemokine CCL5; Citrates; Guinea Pigs; Humans; Interleukin-1beta; Male; Matrix Metalloproteinase 1; Osteoarthritis; RNA, Messenger	2018
Phosphocitrate is potentially a disease-modifying drug for noncrystal-associated osteoarthritis. BioMed research international, 2013, Volume: 2013 Topics: Animals; Antirheumatic Agents; Calcium; Cell Proliferation; Citrates; Down-Regulation; Fibroblasts; Gene Expression Regulation; Guinea Pigs; Humans; Osteoarthritis; Synovial Fluid; Up-Regulation	2013
Biological activities of phosphocitrate: a potential meniscal protective agent. BioMed research international, 2013, Volume: 2013 Topics: Calcinosis; Calcium; Cell Proliferation; Citrates; Collagen; Gene Expression; Humans; Joint Diseases; Knee Joint; Menisci, Tibial; Metabolic Networks and Pathways; Osteoarthritis; Prostaglandins; Vascular Diseases	2013
Expression of phosphocitrate-targeted genes in osteoarthritis menisci. BioMed research international, 2014, Volume: 2014 Topics: Antigens, CD; Calcium; Cartilage, Articular; Citrates; Collagen; Gene Expression Regulation; GPI-Linked Proteins; Humans; Immunity, Innate; Menisci, Tibial; Osteoarthritis; Receptor, Fibroblast Growth Factor, Type 3; Receptors, IgG; Receptors, Immunologic; SOX9 Transcription Factor	2014
Disease-modifying effects of phosphocitrate and phosphocitrate-β-ethyl ester on partial meniscectomy-induced osteoarthritis. BMC musculoskeletal disorders, 2015, Sep-30, Volume: 16 Topics: ADAM Proteins; Animals; Antirheumatic Agents; Calcinosis; Cartilage, Articular; Cell Proliferation; Cells, Cultured; Chemokine CCL5; Citrates; Cyclooxygenase 2; Disease Models, Animal; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Guinea Pigs; Male; Matrix Metalloproteinase 13; Menisci, Tibial; Molecular Structure; Osteoarthritis; Structure-Activity Relationship; Synovial Membrane	2015
Current biological understanding and futuristic views for osteoarthritis treatment: Optimistic or otherwise? International journal of rheumatic diseases, 2016, Volume: 19, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Citrates; Drug Discovery; Forecasting; Humans; Inflammation Mediators; Mesenchymal Stem Cell Transplantation; Osteoarthritis; Rheumatology; Signal Transduction	2016
Inhibition of calcium phosphate-DNA coprecipitates induced cell death by phosphocitrates. Frontiers in bioscience : a journal and virtual library, 2005, Jan-01, Volume: 10 Topics: Animals; Calcium Phosphates; Calcium Pyrophosphate; Cell Death; Citrates; Crystallization; DNA; Endocytosis; HeLa Cells; Humans; Matrix Metalloproteinase 1; Osteoarthritis; Rats; Reverse Transcriptase Polymerase Chain Reaction; Thymidine	2005
New drugs for crystal deposition diseases. Current opinion in rheumatology, 2006, Volume: 18, Issue:2 Topics: Calcinosis; Calcium Compounds; Citrates; Gout; Gout Suppressants; Humans; Joints; Osteoarthritis; Uric Acid	2006