phosphinothricin and Acute-Disease

Glufosinate-containing herbicide is increasingly used in agriculture. Its poisoning is a worldwide concern. More and more patients are poisoned by glufosinate. The aim of this study was to determine the factors associated with mortality of patients with acute poisoning of glufosinate.. This was a retrospective cohort study conducted from January 1998 to October 2015. Using a multivariate logistic analysis, data for the total population were retrospectively analyzed to determine the factors associated with mortality. Various variables were compared in survivors and non-survivors. Significant predictive variables, Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system, the Simplified Acute Physiology Score (SAPS) II, and Sequential Organ Failure Assessment (SOFA) score were compared by analyzing receiver operating characteristic (ROC) curves.. A total of 253 patients (mean age: 58 years) were enrolled. Of the 253 patients, 219 (86.6%) survived and 34 (13.4%) died. Decreased Glasgow Coma Scale (GCS) and bicarbonate (HCO

Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Aminobutyrates; Bicarbonates; Female; Glasgow Coma Scale; Herbicides; Humans; Male; Middle Aged; Prognosis; Republic of Korea; Respiration, Artificial; Retrospective Studies; ROC Curve; Severity of Illness Index; Vasoconstrictor Agents; Young Adult