phosphatidylcholines has been researched along with Non-alcoholic Fatty Liver Disease in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 33 (66.00) | 24.3611 |
| 2020's | 17 (34.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ivashkin, VT; Maev, IV; Mayevskaya, MV; Palgova, LK; Pavlov, CS; Samsonov, AA; Starostin, KM | 1 |
| Lv, J; Lv, Z; Yu, M; Zhang, J; Zhang, Y | 1 |
| Eguchi, A; Fujishiro, M; Fujiwara, N; Hata, M; Hayakawa, Y; Hayata, Y; Hirata, Y; Hoshida, Y; Ikenoue, T; Kawamura, S; Kinoshita, H; Kishikawa, T; Koike, K; Kudo, Y; Kurosaki, S; Matsushita, Y; Nakagawa, H; Nakatsuka, T; Sato, M; Suzuki, N; Tange, M; Tateishi, K; Tateishi, R; Tsuboi, M; Uesugi, M; Umemura, A | 1 |
| DiStefano, JK; Don, J; Gerhard, GS; Piras, IS; Raju, A; Schork, NJ | 1 |
| Gottmann, P; Jähnert, M; Jonas, W; Schürmann, A; Schwerbel, K; Zellner, L | 1 |
| Han, T; Jiang, S; Qian, L; Tang, Y; Tian, S | 1 |
| Gu, J; Guo, C; Kong, A; Li, K; Liu, J; Ren, Z; Shi, H; Tang, M; Zhou, Y | 1 |
| Lv, J; Lv, Z; Yu, M; Zang, X; Zhang, J; Zhang, Y | 1 |
| Chin, CF; Chua, GL; Galam, D; Gao, L; Goh, GB; Leow, WQ; Lim, MS; Lim, YC; Loke, RY; Silver, DL; Tan, BC; Torta, F; Wenk, MR; Wong, BH | 1 |
| Ammollo, CT; Barone, M; Cerletti, C; Colucci, M; Costanzo, S; De Bartolomeo, G; de Gaetano, G; Di Castelnuovo, A; Iacoviello, L; Incampo, F; Portincasa, P; Semeraro, F; Semeraro, N; Storto, M | 1 |
| Bruno, RS; Cichon, MJ; Kopec, RE; Li, J; Riedl, KM; Sasaki, GY | 1 |
| de Vito, C; Dibner, C; Jornayvaz, FR; Loizides-Mangold, U; Montandon, SA; Somm, E | 1 |
| Maev, IV; Palgova, LK; Pavlov, CS; Samsonov, AA; Shirokova, EN; Starostin, KM; Vovk, EI | 2 |
| Brügger, B; Fricker, G; Lüchtenborg, C; Niederhaus, B; Popovic, B | 1 |
| Andreola, F; Argemi, J; Bataller, R; Caballeria, J; Cowart, LA; De Chiara, F; Fondevila, C; Fox, T; Frenguelli, L; Kester, M; Levi, A; Longato, L; Luong, TV; Massey, V; Mazza, G; Montefusco, D; Omenetti, S; Pinzani, M; Rombouts, K; Shanmugavelandy, SS; Zanieri, F | 1 |
| Arola, J; Hyötyläinen, T; Juuti, A; Luukkonen, PK; Orešič, M; Orho-Melander, M; Penttilä, AK; Sammalkorpi, H; Yki-Järvinen, H | 1 |
| Chen, R; Deng, Y; Nie, H; Pan, M; Tang, K; Xie, J; Yang, Q; Zhang, Y; Zheng, C | 1 |
| de Mello, VD; Hanhineva, K; Kaminska, D; Klåvus, A; Ling, C; Männistö, V; Miao, Z; Nilsson, E; Pajukanta, P; Perfilyev, A; Pihlajamäki, J; Sehgal, R | 1 |
| Jacobs, RL; Kennelly, JP; van der Veen, JN; Vance, DE; Vance, JE; Wan, S | 1 |
| Chen, Z; Cui, D; He, B; Jiang, J; Shao, Y; Wu, L; Xie, W; Yan, M; Zhao, Z | 1 |
| Hashimoto, T; Kato, N; Kumrungsee, T; Mitsumoto, K; Nakao, K; Watanabe, R; Yanaka, N; Yonenaka, H | 1 |
| Arteta, B; Aspichueta, P; Buqué, X; Castaño, L; Fresnedo, O; García-Monzón, C; García-Rodriguez, JL; Gomez-Santos, B; Marin, JJG; Nuñez-Garcia, M; Romero, MR; Syn, WK | 1 |
| Byun, S; Guo, G; Kemper, B; Kemper, JK; Kim, YC; Kong, B; Ma, J; Seok, S; Xie, W; Zhang, Y | 1 |
| Fan, B; Guo, XL; Li, JJ; Zhang, P; Zheng, ZS | 1 |
| Babak, О; Bashkirova, А | 1 |
| Ala-Korpela, M; de Mello, VD; Hanhineva, K; Kaminska, D; Kärjä, V; Männistö, V; Pihlajamäki, J; Soininen, P; Tiainen, M | 1 |
| Bader, BL; Dahlhoff, C; Daniel, H; Desmarchelier, C; Fürst, RW; Geisel, J; Haag, A; Hummel, B; Obeid, R; Sailer, M; Ulbrich, SE | 1 |
| Allard, JP; Arendt, BM; Guindi, M; Ma, DW; Noureldin, SA; Sherman, M; Simons, B; Therapondos, G | 1 |
| Brzozowski, T; Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Korolczuk, A; Slomka, M | 1 |
| Aslanidis, C; Buechler, C; Eisinger, K; Hebel, T; Krautbauer, S; Liebisch, G; Schmitz, G | 1 |
| Caraglia, M; De Simone, C; Federico, A; Ferranti, P; Loguercio, C; Murolo, M; Rizzo, MR; Scognamiglio, I; Stiuso, P; Tuccillo, C | 1 |
| Chung, SJ; Chung, YH; Jeong, JH; Kim, HC; Kim, HR; Kim, JH; Lee, HS; Nam, Y; Oh, KW; Park, ES; Sohn, UD | 1 |
| Abenavoli, L; Accattato, F; Foti, D; Greco, M; Gulletta, E; Luzza, F; Milic, N; Nazionale, I; Peta, V | 1 |
| Lu, SC; Mato, JM; Noureddin, M | 1 |
| Chamulitrat, W; Liebisch, G; Okun, JG; Pathil, A; Schmitz, G; Stremmel, W | 1 |
| Daniluk, J; Kandefer-Szerszeń, M; Szuster-Ciesielska, A; Słabczyńska, O; Zwolak, A | 1 |
| Adams, LA; O'Sullivan, TA; Oddo, JL; Properzi, C; Sherriff, JL | 1 |
| Calzada, E; Claypool, SM; Onguka, O | 1 |
| Chamulitrat, W; Deng, X; Jiao, L; Liebisch, G; Schmitz, G; Stremmel, W; Tuma-Kellner, S; Utaipan, T; Wang, J | 1 |
| Aljazi, MB; Atshaves, BP; Brock, JR; Fader, KA; Jones, AD; Lydic, TA; Najt, CP; Olenic, SD; Senthivinayagam, S | 1 |
| Hong, MJ; Hur, HJ; Kim, MS; Kim, SH; Kwon, DY; Park, HS; Park, SJ; Sung, MJ | 1 |
| Angus, PW; Furness, JB; Leung, C; Rivera, L | 1 |
| Liu, Y; Shi, D; Tian, Y; Wang, J; Xu, J; Xue, C; Zhan, Q | 1 |
| Bian, L; Chen, XJ; Dong, XQ; Li, MG; Liang, H; Liu, WJ; Ma, LQ; Wen, ML; Wu, SM; Zhao, JY; Zhu, YZ; Zou, CG | 1 |
| Chen, GY; Fan, JG; Hu, CX; Mi, YQ; Pan, Q; Shen, F; Sun, WL; Xu, GW; Yang, RX | 1 |
| Chaba, T; Jacobs, RL; Niebergall, LJ; Vance, DE | 1 |
| Chaba, T; Jacobs, RL; Ling, J; Vance, DE; Zhu, LF | 1 |
| Dong, XY; Gao, ZJ; Han, Y; Lei, WR; Su, HL; Zhang, Y; Zhu, JY; Zhu, YX | 1 |
| Gendrikson, LN; Iakimchuk, GN | 1 |
5 review(s) available for phosphatidylcholines and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
The critical role of phosphatidylcholine and phosphatidylethanolamine metabolism in health and disease.
Topics: Animals; Fatty Liver, Alcoholic; Humans; Intestinal Mucosa; Lipoproteins, VLDL; Liver; Liver Regeneration; Metabolic Diseases; Mitochondria; Muscle, Skeletal; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamines | 2017 |
Nonalcoholic fatty liver disease: update on pathogenesis, diagnosis, treatment and the role of S-adenosylmethionine.
Topics: Animals; Biomarkers; Disease Models, Animal; Humans; Liver; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; United States | 2015 |
Choline, Its Potential Role in Nonalcoholic Fatty Liver Disease, and the Case for Human and Bacterial Genes.
Topics: Bacteria; Choline; Deficiency Diseases; Humans; Liver; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamines; Polymorphism, Genetic | 2016 |
Phosphatidylethanolamine Metabolism in Health and Disease.
Topics: Alzheimer Disease; Animals; Autophagy; Candida; Carboxy-Lyases; Cell Membrane; Cytidine Diphosphate; Ethanolamines; Humans; Lipid Metabolism; Methylation; Mitochondria; Non-alcoholic Fatty Liver Disease; Oxidative Phosphorylation; Parkinson Disease; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Prions; Protein Processing, Post-Translational; Virulence | 2016 |
The role of the gut microbiota in NAFLD.
Topics: Bile Acids and Salts; Diet; Disease Progression; Ethanol; Exercise; Fatty Acids, Volatile; Fungi; Gastrointestinal Microbiome; Gastrointestinal Motility; Glucose; Gram-Negative Bacteria; Gram-Positive Bacteria; Host-Pathogen Interactions; Humans; Intestines; Liver; Methylamines; Non-alcoholic Fatty Liver Disease; Permeability; Phosphatidylcholines; Prebiotics; Probiotics; Receptors, G-Protein-Coupled; Sleep; Viruses | 2016 |
6 trial(s) available for phosphatidylcholines and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Randomised trial of chronic supplementation with a nutraceutical mixture in subjects with non-alcoholic fatty liver disease.
Topics: Adult; Aged; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Choline; Curcumin; Dietary Supplements; Docosahexaenoic Acids; Double-Blind Method; Drug Combinations; Female; Fibrinolysis; gamma-Glutamyltransferase; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Silymarin; Tocopherols | 2020 |
Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up.
Topics: Adult; Cholesterol, LDL; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Lipid Metabolism; Liver; Male; Melatonin; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Triglycerides; Tryptophan; Young Adult | 2014 |
Serum oxidative stress markers and lipidomic profile to detect NASH patients responsive to an antioxidant treatment: a pilot study.
Topics: Adult; Antioxidants; Biomarkers; Case-Control Studies; Catalase; Female; Hep G2 Cells; Humans; Lipid Metabolism; Male; Metabolomics; Nitric Oxide; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Phosphatidylcholines; Pilot Projects; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2014 |
Effects of Mediterranean diet supplemented with silybin-vitamin E-phospholipid complex in overweight patients with non-alcoholic fatty liver disease.
Topics: Adult; Biomarkers; Body Mass Index; Cholesterol; Diet, Mediterranean; Dietary Supplements; Humans; Italy; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Overweight; Phosphatidylcholines; Prospective Studies; Silybin; Silymarin; Time Factors; Treatment Outcome; Triglycerides; Vitamin E; Waist Circumference | 2015 |
[Efficacy comparison between bicyclol and polyene phosphatidylcholine treatments for the patients with nonalcoholic fatty liver disease].
Topics: Adult; Biphenyl Compounds; Fatty Liver; Female; Humans; Hypolipidemic Agents; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Young Adult | 2011 |
[Study of clinical efficiency of essential phospholipids and silymarin combination in nonalcoholic and alcoholic steatohepatitis].
Topics: Drug Administration Schedule; Drug Therapy, Combination; Fatty Liver; Fatty Liver, Alcoholic; Female; Humans; Lipid Peroxidation; Liver Function Tests; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Silymarin; Treatment Outcome | 2011 |
39 other study(ies) available for phosphatidylcholines and Non-alcoholic Fatty Liver Disease
| Article | Year |
|---|---|
Safety and Effectiveness of Essential Phospholipids Paste in Patients with Non-alcoholic Fatty Liver Disease or Viral Hepatitis.
Topics: Adult; Female; Hepatitis B; Hepatitis C; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Treatment Outcome | 2021 |
Lipidomic-based investigation into the therapeutic effects of polyene phosphatidylcholine and Babao Dan on rats with non-alcoholic fatty liver disease.
Topics: Animals; Diet; Drugs, Chinese Herbal; Lipid Metabolism; Lipidomics; Liver; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Rats; Rats, Sprague-Dawley | 2022 |
Inhibiting SCAP/SREBP exacerbates liver injury and carcinogenesis in murine nonalcoholic steatohepatitis.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Animals; Carcinogenesis; Intracellular Signaling Peptides and Proteins; Liver Neoplasms; Membrane Proteins; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sterol Regulatory Element Binding Protein 1 | 2022 |
Hepatic PEMT Expression Decreases with Increasing NAFLD Severity.
Topics: Female; Fibrosis; Humans; Inflammation; Liver; Liver Cirrhosis; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase | 2022 |
Alterations of Lipid Profile in Livers with Impaired Lipophagy.
Topics: Animals; Autophagy; Fatty Acids; Fatty Acids, Omega-3; Humans; Lipid Metabolism; Liver; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phospholipids; Triglycerides | 2022 |
DHA-enriched phosphatidylcholine from
Topics: Animals; Diet, High-Fat; Dysbiosis; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines | 2022 |
Cadmium perturbed lipid profile and induced liver dysfunction in mice through phosphatidylcholine remodeling and promoting arachidonic acid synthesis and metabolism.
Topics: Animals; Arachidonic Acid; Cadmium; Delta-5 Fatty Acid Desaturase; Lipid Metabolism; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines | 2022 |
Changes in Lipidomics, Metabolomics, and the Gut Microbiota in CDAA-Induced NAFLD Mice after Polyene Phosphatidylcholine Treatment.
Topics: Animals; Gastrointestinal Microbiome; Lipidomics; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines | 2023 |
Blood-derived lysophospholipid sustains hepatic phospholipids and fat storage necessary for hepatoprotection in overnutrition.
Topics: Animals; Dietary Fats; Liver; Lysophospholipids; Mice; Non-alcoholic Fatty Liver Disease; Overnutrition; Phosphatidylcholines; Phospholipids | 2023 |
Green Tea Extract Treatment in Obese Mice with Nonalcoholic Steatohepatitis Restores the Hepatic Metabolome in Association with Limiting Endotoxemia-TLR4-NFκB-Mediated Inflammation.
Topics: Animals; Bile Acids and Salts; Catechin; Diet, High-Fat; Endotoxemia; Inflammation; Insulin Resistance; Liver; Male; Metabolome; Mice, Inbred C57BL; Mice, Obese; NF-kappa B; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Plant Extracts; Tea; Toll-Like Receptor 4 | 2019 |
Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism.
Topics: Animals; Atherosclerosis; Choline; Diet; Diet, Atherogenic; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Lipidomics; Male; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sphingolipids | 2019 |
Effectiveness of phosphatidylcholine in alleviating steatosis in patients with non-alcoholic fatty liver disease and cardiometabolic comorbidities (MANPOWER study).
Topics: Adult; Comorbidity; Diabetes Mellitus, Type 2; Humans; Hypertension; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Prevalence; Prospective Studies; Workforce | 2020 |
Lipid Profiles of Five Essential Phospholipid Preparations for the Treatment of Nonalcoholic Fatty Liver Disease: A Comparative Study.
Topics: Clinical Decision-Making; Humans; Mass Spectrometry; Non-alcoholic Fatty Liver Disease; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylethanolamines | 2020 |
Effectiveness of phosphatidylcholine as adjunctive therapy in improving liver function tests in patients with non-alcoholic fatty liver disease and metabolic comorbidities: real-life observational study from Russia.
Topics: Adult; Comorbidity; Diabetes Mellitus, Type 2; Humans; Liver Function Tests; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Russia | 2020 |
Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH.
Topics: Adenylate Kinase; Animals; Antioxidants; Apoptosis; Cell Proliferation; Ceramides; Choline; Diet; Diglycerides; Energy Metabolism; Fatty Liver; Feeding Behavior; Hematopoietic Stem Cells; Homeostasis; Humans; Lipidomics; Liposomes; Male; Methionine; Mice, Inbred BALB C; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphorylation; Protein Subunits; Signal Transduction | 2020 |
MARC1 variant rs2642438 increases hepatic phosphatidylcholines and decreases severity of non-alcoholic fatty liver disease in humans.
Topics: Humans; Liver; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Severity of Illness Index | 2020 |
Prevention of Nonalcoholic Hepatic Steatosis by Shenling Baizhu Powder: Involvement of Adiponectin-Induced Inhibition of Hepatic SREBP-1c.
Topics: Adiponectin; Animals; Cholesterol; Diet; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Acid Synthases; Lipid Metabolism; Liver; Male; Microcirculation; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Rats; Rats, Wistar; Sterol Regulatory Element Binding Protein 1; Triglycerides | 2020 |
Serum aromatic and branched-chain amino acids associated with NASH demonstrate divergent associations with serum lipids.
Topics: Adult; Amino Acids, Branched-Chain; Bariatric Surgery; Humans; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines | 2021 |
The imbalance of Th17/Treg cells is involved in the progression of nonalcoholic fatty liver disease in mice.
Topics: Animals; Capsules; Cells, Cultured; Cytokines; Disease Models, Animal; Female; Forkhead Transcription Factors; Humans; Immunomodulation; Inflammation; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; T-Lymphocytes, Regulatory; Th1-Th2 Balance; Th17 Cells | 2017 |
Time-course microarrays reveal early activation of the immune transcriptome in a choline-deficient mouse model of liver injury.
Topics: Animals; Choline; Choline Deficiency; Chromatography, Liquid; Disease Models, Animal; Gene Expression Profiling; Hepatocytes; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred ICR; Non-alcoholic Fatty Liver Disease; Oligonucleotide Array Sequence Analysis; Phosphatidylcholines; RNA, Messenger; STAT1 Transcription Factor; Time Factors; Transcriptome | 2017 |
Osteopontin regulates the cross-talk between phosphatidylcholine and cholesterol metabolism in mouse liver.
Topics: Adult; Aged; Animals; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Disease Progression; Extracellular Space; Female; Gene Knockout Techniques; Hepatocytes; Humans; Liver; Male; Mice; Middle Aged; Non-alcoholic Fatty Liver Disease; Osteopontin; Phosphatidylcholines; Young Adult | 2017 |
AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle.
Topics: Animals; Carbon Cycle; Fibroblast Growth Factors; Glycine N-Methyltransferase; Humans; Liver; Male; Mice; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Protein Binding; Receptors, Aryl Hydrocarbon; Receptors, Cytoplasmic and Nuclear; S-Adenosylmethionine | 2018 |
The efficacy of saxagliptin in T2DM patients with non-alcoholic fatty liver disease: preliminary data.
Topics: Adamantane; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptides; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sulfonylurea Compounds; Treatment Outcome | 2019 |
RESULTS OF CORRECTION OF THE HEPATIC STEATOSIS ON THE BACKGROUND OF HYPERTENSION AND OVERWEIGHT WITH HELP OF ESSENTIAL PHOSPHOLIPID COMPLEX.
Topics: Humans; Hypertension; Non-alcoholic Fatty Liver Disease; Overweight; Phosphatidylcholines | 2019 |
Total liver phosphatidylcholine content associates with non-alcoholic steatohepatitis and glycine N-methyltransferase expression.
Topics: Adult; Animals; Female; Glycine N-Methyltransferase; Humans; Liver; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Proton Magnetic Resonance Spectroscopy; RNA, Messenger | 2019 |
Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.
Topics: Amino Acids; Animals; Betaine-Homocysteine S-Methyltransferase; Carbon; Cell Line, Tumor; Cystathionine beta-Synthase; Diet, High-Fat; Fatty Liver; Gene Expression Regulation, Enzymologic; Homeostasis; Lipid Metabolism; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; PPAR alpha; Rats; Sequence Analysis, DNA | 2013 |
Nonalcoholic fatty liver disease is associated with lower hepatic and erythrocyte ratios of phosphatidylcholine to phosphatidylethanolamine.
Topics: Animals; Erythrocytes; Humans; Liver; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamines | 2013 |
Lipidomic analysis of the liver from high-fat diet induced obese mice identifies changes in multiple lipid classes.
Topics: alpha-Linolenic Acid; Animals; Cholesterol; Decanoic Acids; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Lauric Acids; Lipid Metabolism; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylcholines; Phospholipids; Plasmalogens; Sphingomyelins | 2014 |
Beneficial effects of phosphatidylcholine on high-fat diet-induced obesity, hyperlipidemia and fatty liver in mice.
Topics: Adipocytes; Animals; Apolipoproteins E; Diet, High-Fat; Hyperlipidemias; Leptin; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylcholines; Weight Gain | 2014 |
Ursodeoxycholyl Lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD.
Topics: Aldehyde Oxidase; Animals; Arachidonic Acid; Carnitine O-Palmitoyltransferase; Cholagogues and Choleretics; Diet, High-Fat; Disease Models, Animal; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fatty Acids; Lipid Metabolism; Liver; Lysophospholipids; Mass Spectrometry; Mice; Mitochondria; Non-alcoholic Fatty Liver Disease; Oxidation-Reduction; Phosphatidylcholines; PPAR alpha; Real-Time Polymerase Chain Reaction; RNA, Messenger; Transcriptome; Ursodeoxycholic Acid | 2015 |
Hyperreactivity of Blood Leukocytes in Patients with NAFLD to Ex Vivo Lipopolysaccharide Treatment Is Modulated by Metformin and Phosphatidylcholine but Not by Alpha Ketoglutarate.
Topics: Cytokines; Dose-Response Relationship, Drug; Female; Gene Expression Regulation; Humans; Ketoglutaric Acids; Leukocytes; Lipopolysaccharides; Male; Metabolic Syndrome; Metformin; Middle Aged; Monocytes; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylcholines; Toll-Like Receptor 4 | 2015 |
iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling.
Topics: Animals; Apoptosis; Arachidonic Acid; Blood Glucose; Cholesterol Esters; Disease Models, Animal; Docosahexaenoic Acids; Fatty Acids; Gene Expression Regulation; Genotype; Group VI Phospholipases A2; Insulin; Insulin Resistance; Liver; Lysophospholipids; Male; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction; Phenotype; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; PPAR gamma; Triglycerides | 2016 |
Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis.
Topics: Animals; Caspase 1; CCAAT-Enhancer-Binding Proteins; Choline Deficiency; Cytokines; Lipoproteins, LDL; Liver; Liver Cirrhosis; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Perilipin-2; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Triglycerides | 2016 |
Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obese mice.
Topics: Animals; Diet, High-Fat; Genistein; Glucose; HEK293 Cells; Humans; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylcholines; PPAR alpha | 2016 |
Eicosapentaenoic Acid-Enriched Phosphatidylcholine Attenuated Hepatic Steatosis Through Regulation of Cholesterol Metabolism in Rats with Nonalcoholic Fatty Liver Disease.
Topics: Animals; Carrier Proteins; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Disease Models, Animal; Eicosapentaenoic Acid; Gene Expression Profiling; Gene Expression Regulation; Hydroxymethylglutaryl CoA Reductases; Male; Non-alcoholic Fatty Liver Disease; Orotic Acid; Phosphatidylcholines; Random Allocation; Rats; Rats, Wistar; Sea Cucumbers; Treatment Outcome | 2017 |
Ameliorative effects of Compound K and ginsenoside Rh1 on non-alcoholic fatty liver disease in rats.
Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Diet, High-Fat; Disease Models, Animal; Gene Expression Regulation; Ginsenosides; Liver Function Tests; Male; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Rats; Tissue Inhibitor of Metalloproteinase-1 | 2017 |
[A serum lipidomic study of patients with non-alcoholic fatty liver disease].
Topics: Case-Control Studies; Humans; Lipid Metabolism; Lysophospholipids; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Plasmalogens; Triglycerides | 2017 |
Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis.
Topics: Adenoviridae; Animals; Betaine; Ceramides; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Vectors; Lipotropic Agents; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Triglycerides | 2011 |
Hepatic ratio of phosphatidylcholine to phosphatidylethanolamine predicts survival after partial hepatectomy in mice.
Topics: Animals; Choline; Choline-Phosphate Cytidylyltransferase; Dietary Fats; Dietary Supplements; Disease Models, Animal; Disease Progression; Fatty Liver; Hepatectomy; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Predictive Value of Tests; Survival Rate | 2012 |