Page last updated: 2024-09-05

phosphatidylcholines and Liver Steatosis

phosphatidylcholines has been researched along with Liver Steatosis in 117 studies

Research

Studies (117)

TimeframeStudies, this research(%)All Research%
pre-199047 (40.17)18.7374
1990's7 (5.98)18.2507
2000's18 (15.38)29.6817
2010's35 (29.91)24.3611
2020's10 (8.55)2.80

Authors

AuthorsStudies
Kemmochi, Y; Kobayashi, A; Masuyama, T; Muta, K; Saito, K; Saito, Y; Sugai, S1
Han, C; Hu, S; Kang, B; Li, L; Liu, H; Ning, R; Teng, Y; Wei, R; Wei, S; Xu, H1
Bowen, T; Cato, ML; Cohen, DE; Druzak, SA; El Bejjani, M; Fu, H; Maner-Smith, KM; Mays, SG; Mo, X; Ortlund, EA; Sugiyama, A; Tardelli, M; Tillman, MC; Xie, Y1
Abomughaid, M; Coorssen, JR; Douglas, MW; George, J; Gloss, BS; Malladi, C; Pickford, R; Read, SA; Tay, ESE1
Abukawa, D; Ando, T; Azuma, Y; Fukuda, A; Hayashi, H; Inui, A; Kaji, S; Kasahara, M; Kusuhara, H; Mizuno, S; Mizuno, T; Nakano, S; Okamoto, T; Sabu, Y; Sakamoto, S; Shimizu, S; Suzuki, M; Takahashi, S; Tamura, R; Zen, Y1
Arai, K; Ikejima, K; Ishizuka, K; Kon, K; Lee-Okada, HC; Uchiyama, A; Yamashina, S; Yokomizo, T1
Andreola, F; Argemi, J; Bataller, R; Caballeria, J; Cowart, LA; De Chiara, F; Fondevila, C; Fox, T; Frenguelli, L; Kester, M; Levi, A; Longato, L; Luong, TV; Massey, V; Mazza, G; Montefusco, D; Omenetti, S; Pinzani, M; Rombouts, K; Shanmugavelandy, SS; Zanieri, F1
Andriamihaja, M; Blachier, F; Blais, A1
Bjellaas, T; Chella Krishnan, K; Dalen, KT; Drevon, CA; Gundersen, TE; Hui, ST; Lang, J; Lusis, AJ; Mehrabian, M; Meng, Y; Norheim, F; Pan, C; Parks, BW; Péterfy, M; Reue, K; Seldin, MM; Vergnes, L; Ward, JA1
Bohler, HCL; Dryden, GW; Han, X; Kumar, A; Lei, C; McClain, CJ; Merchant, ML; Mu, J; Park, JW; Qin, C; Qiu, X; Sriwastva, MK; Sundaram, K; Teng, Y; Wang, B; Xu, F; Xu, Z; Yan, J; Zhang, HG; Zhang, L; Zhang, S; Zhang, X1
Hunt, AN; Lagoudakis, P; Mahajan, S; Malur, A; Monfort, T; Postle, AD; Thomassen, MJ1
Mehtiyev, SN; Mehtiyeva, OA1
Birnbaum, MJ; Gelfer, R; Quinn, WJ; Rader, DJ; Shewale, SV; Titchenell, PM; Wan, M1
Fujiwara, Y; Hayashi, Y; Ichi, I; Ishikawa, T; Shimamura, A1
de Novellis, F; De Rosa, M; Giori, AM; Pirozzi, AVA; Schiraldi, C; Scognamiglio, I; Stellavato, A; Vassallo, V1
Goda, K; Kobayashi, A; Muta, K; Saito, K; Saito, Y; Sugai, S1
Bader, BL; Dahlhoff, C; Daniel, H; Desmarchelier, C; Fürst, RW; Geisel, J; Haag, A; Hummel, B; Obeid, R; Sailer, M; Ulbrich, SE1
Alonso, C; Aspichueta, P; Aurrekoetxea, I; Beraza, N; Buqué, X; Cano, A; Fernández-Ares, L; Finnell, RH; García-Rodríguez, JL; Lu, SC; Luka, Z; Martínez-Arranz, I; Martínez-Chantar, ML; Martínez-Uña, M; Mato, JM; Mestre, D; Varela-Rey, M; Wagner, C1
Cao, G; Ding, T; Dong, J; Jiang, XC; Kuo, MS; Li, Y; Li, Z1
Brzozowski, T; Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Korolczuk, A; Slomka, M1
Aslanidis, C; Buechler, C; Eisinger, K; Hebel, T; Krautbauer, S; Liebisch, G; Schmitz, G1
Adams, C; Barroso, I; Brown, RJ; Cochran, E; Dev Borman, A; Girousse, A; Gorden, P; Kory, N; Lim, K; O'Rahilly, S; Payne, F; Robbins, A; Russel-Jones, D; Saudek, V; Savage, DB; Semple, RK; Sleigh, A; Walther, TC; Xue, Y1
Chaba, T; Dyck, JR; Gao, X; Gomez-Muñoz, A; Jacobs, RL; Koonen, DP; Lingrell, S; Ordoñez, M; van der Veen, JN; Vance, DE; Zhu, L1
Aoki, J; Arai, H; Asou, H; Ishitani, R; Kano, K; Kato, K; Mihara, E; Morita, J; Nishimasu, H; Nureki, O; Sakagami, H; Sato, T; Takagi, J; Takita, H; Tokuyama, H; Ueda, H; Yamamoto, Y1
Abramowicz, S; Chan, RB; Di Paolo, G; Hsieh, J; Hussain, MM; Ichi, I; Iqbal, J; Koseki, M; Lefkowitch, JH; Molusky, MM; Rader, DJ; Takiguchi, S; Tall, AR; Tascau, L; Welch, CL; Westerterp, M; Yakushiji, E; Yamashita, S1
Chen, DF; Wang, T1
Walker, AK1
Bruce German, J; Esfandiari, F; Halsted, CH; Zivkovic, AM1
Chico, Y; Costán, G; De la Mata, M; Díaz-López, C; González, R; González-Rubio, S; Hidalgo, AB; Muntané, J; Ochoa, B; Padillo, FJ; Ranchal, I; Sánchez-Garrido, MA1
Conway, R; Harris, L; Mustonen, AM; Nieminen, P; Pal, C; Rouvinen-Watt, K; Saarela, S; Strandberg, U1
Arimoto, J; Caldwell, SH; Fujii, H; Iezzoni, JC; Ikura, Y; Itabe, H; Kawada, N; Naruko, T; Park, SH; Sugioka, K; Ueda, M1
Cao, G; Dyck, JR; Jacobs, RL; Kennedy, BP; Koonen, DP; Kuo, MS; Lingrell, S; Peake, DA; Proctor, SD; Sletten, T; Su, B; Vance, DE; Zhao, Y1
Chung, RW; Cohn, JS; Kamili, A; Meikle, PJ; Tandy, S; Wat, E; Weir, JM1
Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Slomka, M1
Ikura, Y; Mita, E; Nakamori, S1
Busby, SA; Griffin, PR; Lee, JM; Lee, YK; Mamrosh, JL; Moore, DD; Ortlund, EA; Pathak, MC1
Ingraham, HA1
Chaba, T; Jacobs, RL; Niebergall, LJ; Vance, DE1
Chaba, T; Jacobs, RL; Ling, J; Vance, DE; Zhu, LF1
Dong, XY; Gao, ZJ; Han, Y; Lei, WR; Su, HL; Zhang, Y; Zhu, JY; Zhu, YX1
Flamment, M; Foufelle, F1
Andreone, P; Brisc, C; Brisc, MC; Bugianesi, E; Chiaramonte, M; Cursaro, C; Danila, M; de Sio, I; Del Vecchio Blanco, C; Federico, A; Floreani, A; Freni, MA; Grieco, A; Groppo, M; Lazzari, R; Lobello, S; Loguercio, C; Lorefice, E; Margotti, M; Miele, L; Milani, S; Okolicsanyi, L; Palasciano, G; Portincasa, P; Saltarelli, P; Smedile, A; Somalvico, F; Sorrentino, P; Spadaro, A; Sporea, I; Tuccillo, C; Vecchione, R1
Gendrikson, LN; Iakimchuk, GN1
Bauer, S; Buechler, C; Eisinger, K; Liebisch, G; Neumeier, M; Ouchi, N; Schmitz, G; Walsh, K; Wanninger, J1
Lingrell, S; van der Veen, JN; Vance, DE1
Vance, DE1
Fève, B; Kuhn, E; Lombès, M1
Zeisel, SH1
Khokhlacheva, NA; Suchkova, EV; Vakhrushev, IaM1
SCHETTLER, G1
JANSEN, L1
HARTMANN, F; HESS, RG1
LEWIS, W; SNYDER, F1
HERBERTSON, BM; WALLACE, ME1
Suchkova, EV; Vakhrushev, IaM1
Leiter, EH; Pan, HJ; Reifsnyder, P; Vance, DE; Xiao, Q1
Arakawa, T; Ehara, S; Fukushima, H; Ikura, Y; Inoue, T; Itabe, H; Jomura, H; Kawada, N; Naruko, T; Nishiguchi, S; Ohsawa, M; Suekane, T; Ueda, M1
Agellon, LB; Allen, TM; Jewell, L; Li, Z; Mason, A; Umeda, M; Vance, DE1
Chen, YE; Leiter, EH; Lin, Y; Pan, HJ; Vance, DE1
Nyirenda, MJ; Raubenheimer, PJ; Walker, BR1
Li, Z; Vance, DE1
Wang, YL1
Allen, RH; daCosta, KA; Fischer, LM; Kwock, L; Lu, TS; Stabler, SP; Stewart, PW; Zeisel, SH1
Ham, L; Havekes, L; Poelmann, R; Ramakers, R; van der Greef, J; van Dijk, KW; Van Eck, M; van Ginneken, V; Verhey, E; Voshol, P1
Ono, M; Saibara, T1
Ahn, EJ; Chung, BC; Kim, H; Kong, G; Moon, MH1
Abdulla, YH; Adams, CW; Bayliss, OB; Morgan, RS1
Amore, MG; Bertino, G; Calcara, G; Caruso, L; Rapisarda, F; Trischitta, C1
Bozovic, MG; Coleman, RA; Grant, JP; Hall, RI; Quarfordt, SH; Ross, LH1
Noda, K; Okita, T1
Horejsová, M; Urban, J1
Kupcová, V; Laktis, K; Szántová, M; Turecký, L; Uhlíková, E1
Glasa, J; Hlavatý, I; Holomán, J; Lukácsová, M; Prachar, V; Veningerová, M1
Eder, K1
Kolbasov, SE; Lebedev, VP; Melikhova, MV; Stroĭkova, GV; Zamuruev, ON1
Lieber, CS1
Polin, D; Wolford, JH1
Aizawa, Y; Negishi, I1
Antonenko, NI; Gitel', NP; Ol'binskaia, LI; Pogromov, AP; Smolianitskiĭ, AIa1
Alliet, J; Gourdier, D; Köbele, H; Théret, CG2
Bartsch, GG; Gerber, GB1
Ament, ME; Buchman, AL; Dubin, M; Eckhert, CD; Gornbein, J; Jenden, D; Moukarzel, A; Rice, K; Roch, MH1
Gilev, AF; Golubchikova, NA; Sergeev, SG; Ust'iantseva, IM1
Fujimoto, K; Kaneda, T; Miyazawa, T; Yoshida, LS1
Larkin, EC; Rao, GA; Riley, DE1
Voskresenskiĭ, ON1
Crawford, MA; Fiennes, RN; Sinclair, AJ1
Fatterpaker, P; Koppikar, SV; Satav, JG; Sreenivasan, A1
Oberdisse, E; von Lehmann, V1
Sgoutas, DS1
Glende, EA; Morgan, WS1
Clément, J; Di Costanzo, G1
Borgman, RF; Haselden, FH1
Morita, A1
Misra, R; Misra, UK; Venkitasubramanian, TA1
Jipp, P; Ravens, KG; Salm, M1
Binaglia, L; Brunetti, M; Michal, G; Porcellati, G; Roberti, R1
Frey, CF; Goswami, SK1
Brooks, SG; Dobbins, WO; Fallon, HJ; Rollins, EL1
Witting, LA1
Ghoshal, AK; Hartroft, WS; Monserrat, AJ; Porta, EA1
Chalvardjian, A1
Kanetaka, T; Naito, C; Oda, T; Shikata, T; Suzuki, H1
Lisovskiĭ, VA1
Dominiczak, K; Samochowiec, L; Wójcicki, J1
Balcerzak, SP; Heinle, EW; Westerman, MP1
Cornatzer, WE; Miller, JE1
Thomas, H1
Isozaki, M; Sano, M; Yamamoto, A1
MacDonald, G; Mookerjea, S; Thompson, W1
Beare-Rogers, JL1
Adams, CW; Baker, RW; Morgan, RS; Orton, CC1
Hansen, JD; Truswell, AS; Wannenburg, P; Watson, CE1
Fallon, HJ; Klatskin, G; Pesch, LA1
Haines, DS1

Reviews

8 review(s) available for phosphatidylcholines and Liver Steatosis

ArticleYear
Sulfur-Containing Amino Acids and Lipid Metabolism.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Amino Acids, Sulfur; Animals; Atherosclerosis; Betaine; Cholesterol; Cysteine; Dietary Proteins; Dietary Supplements; Fatty Liver; Glutathione; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; Sulfur; Sulfur Compounds; Taurine

2020
[[New Paradigm Challenges of Steatosis Treatment in the Practice Therapist].]
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2016, Issue:5

    Topics: Adult; Drug Combinations; Fatty Liver; Glycyrrhizic Acid; Humans; Liver Cirrhosis; Liver Function Tests; Male; Phosphatidylcholines; Practice Patterns, Physicians'; Treatment Outcome; Ultrasonography; Ursodeoxycholic Acid

2016
1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver.
    Trends in endocrinology and metabolism: TEM, 2017, Volume: 28, Issue:1

    Topics: Animals; Carbon Cycle; Diabetes Mellitus, Type 2; Fatty Liver; Humans; Lipogenesis; Phosphatidylcholines; S-Adenosylmethionine

2017
Physiological roles of phosphatidylethanolamine N-methyltransferase.
    Biochimica et biophysica acta, 2013, Volume: 1831, Issue:3

    Topics: Animals; Choline; Diet, High-Fat; Endoplasmic Reticulum; Estrogens; Fatty Liver; Humans; Liver; Mice; Mice, Knockout; Mitochondria, Liver; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Receptors, LDL; Sp1 Transcription Factor

2013
[New pathophysiological mechanisms of metabolic syndrome: implication of orphan nuclear receptors?].
    Annales d'endocrinologie, 2012, Volume: 73 Suppl 1

    Topics: Animals; Fatty Liver; Glucocorticoids; Humans; Hypoglycemic Agents; Liver X Receptors; Metabolic Syndrome; Mice; Mice, Knockout; Orphan Nuclear Receptors; Phosphatidylcholines; Receptors, Cytoplasmic and Nuclear

2012
Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment.
    The American journal on addictions, 2001, Volume: 10, Issue:s1

    Topics: beta Carotene; Ethanol; Fatty Liver; Hepatitis C; Hepatitis, Alcoholic; Humans; Lipid Peroxidation; Liver Cirrhosis; NAD; Nutritional Status; Oxidative Stress; Phosphatidylcholines; S-Adenosylmethionine; Vitamin A

2001
[Pancreatic hormones and arteriosclerosis].
    Kardiologiia, 1967, Volume: 7, Issue:12

    Topics: Aging; Animals; Arteriosclerosis; Blood Proteins; Cholesterol; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dogs; Fatty Acids; Fatty Liver; Glucagon; Guinea Pigs; Hypercholesterolemia; Insulin; Insulin Secretion; Lipotropic Agents; NADP; Obesity; Pancreatectomy; Phosphatidylcholines; Rabbits; Rats; Sterols; Tissue Extracts

1967
Fatty liver in kwashiorkor.
    Nutrition reviews, 1969, Volume: 27, Issue:9

    Topics: Biopsy; Child; Deficiency Diseases; Fatty Liver; Folic Acid Deficiency; Humans; Kwashiorkor; Lipoproteins; Lipotropic Agents; Phosphatidylcholines; Protein Deficiency; Time Factors; Vitamin B 12 Deficiency

1969

Trials

11 trial(s) available for phosphatidylcholines and Liver Steatosis

ArticleYear
Effects of treatment with melatonin and tryptophan on liver enzymes, parameters of fat metabolism and plasma levels of cytokines in patients with non-alcoholic fatty liver disease--14 months follow up.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2014, Volume: 65, Issue:1

    Topics: Adult; Cholesterol, LDL; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Humans; Lipid Metabolism; Liver; Male; Melatonin; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Triglycerides; Tryptophan; Young Adult

2014
The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:5

    Topics: Adult; Antioxidants; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Hepatocytes; Humans; Insulin Resistance; Liver; Liver Cirrhosis; Liver Function Tests; Male; Melatonin; Middle Aged; Oxidative Stress; Phosphatidylcholines; Triglycerides; Tryptophan; Young Adult

2010
[Efficacy comparison between bicyclol and polyene phosphatidylcholine treatments for the patients with nonalcoholic fatty liver disease].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2011, Volume: 19, Issue:7

    Topics: Adult; Biphenyl Compounds; Fatty Liver; Female; Humans; Hypolipidemic Agents; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Young Adult

2011
Silybin combined with phosphatidylcholine and vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial.
    Free radical biology & medicine, 2012, May-01, Volume: 52, Issue:9

    Topics: Body Mass Index; Fatty Liver; Humans; Phosphatidylcholines; Romania; Silybin; Silymarin; Vitamin E

2012
[Study of clinical efficiency of essential phospholipids and silymarin combination in nonalcoholic and alcoholic steatohepatitis].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2011, Issue:7

    Topics: Drug Administration Schedule; Drug Therapy, Combination; Fatty Liver; Fatty Liver, Alcoholic; Female; Humans; Lipid Peroxidation; Liver Function Tests; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Silymarin; Treatment Outcome

2011
[Use of essentiale and cholagogum in prevention of cholelithiasis in fat hepatosis with concomitant cholecystitis].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:2

    Topics: Adult; Anticholesteremic Agents; Cholecystitis; Cholelithiasis; Drug Combinations; Drug Therapy, Combination; Fatty Liver; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Plant Extracts

2005
[Yiqi Huoxue Recipe combined with polyene phosphatidycholine capsule in treating 50 patients with non-alcoholic fatty hepatitis].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2007, Volume: 27, Issue:2

    Topics: Adult; Capsules; Drug Therapy, Combination; Drugs, Chinese Herbal; Fatty Liver; Female; Humans; Hypolipidemic Agents; Male; Middle Aged; Phosphatidylcholines; Phytotherapy; Syndrome; Treatment Outcome

2007
Sex and menopausal status influence human dietary requirements for the nutrient choline.
    The American journal of clinical nutrition, 2007, Volume: 85, Issue:5

    Topics: Adolescent; Adult; Aged; Choline; Choline Deficiency; Dose-Response Relationship, Drug; Fatty Liver; Female; Folic Acid; Humans; Male; Menopause; Middle Aged; Muscle, Skeletal; Nutrition Policy; Nutritional Requirements; Phosphatidylcholines; Sex Factors

2007
[The effect of polyene phosphatidylcholine (Essentiale forte) in the treatment of liver steatosis and ultrasound findings--preliminary study].
    Casopis lekaru ceskych, 1994, Jun-13, Volume: 133, Issue:12

    Topics: Adolescent; Adult; Fatty Liver; Female; Humans; Liver; Phosphatidylcholines; Ultrasonography

1994
[Use of "Essenciale" in the treatment of liver diseases].
    Klinicheskaia meditsina, 1978, Volume: 56, Issue:10

    Topics: Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Fatty Acids, Unsaturated; Fatty Liver; Female; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Diseases; Male; Middle Aged; Phosphatidylcholines

1978
Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients.
    Gastroenterology, 1992, Volume: 102, Issue:4 Pt 1

    Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Carnitine; Choline; Choline Deficiency; Fatty Liver; Female; Humans; Male; Middle Aged; Parenteral Nutrition, Total; Phosphatidylcholines

1992

Other Studies

98 other study(ies) available for phosphatidylcholines and Liver Steatosis

ArticleYear
Phosphatidylcholine (18:0/20:4), a potential biomarker to predict ethionamide-induced hepatic steatosis in rats.
    Journal of applied toxicology : JAT, 2022, Volume: 42, Issue:9

    Topics: Animals; Biomarkers; Ethionamide; Fatty Liver; Humans; Liver; Phosphatidylcholines; Rats; Triglycerides

2022
Lipidomics analysis reveals new insights into the goose fatty liver formation.
    Poultry science, 2023, Volume: 102, Issue:3

    Topics: Animals; Chickens; Fatty Liver; Geese; Lipidomics; Phosphatidylcholines; Triglycerides

2023
Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice.
    Nature communications, 2023, 05-12, Volume: 14, Issue:1

    Topics: Animals; Diet; Fatty Liver; Ligands; Liver; Male; Mice; Phosphatidylcholines; PPAR delta

2023
PEMT Mediates Hepatitis C Virus-Induced Steatosis, Explains Genotype-Specific Phenotypes and Supports Virus Replication.
    International journal of molecular sciences, 2023, May-15, Volume: 24, Issue:10

    Topics: Cholesterol; Fatty Liver; Genotype; Hepacivirus; Hepatitis C; Hepatitis C, Chronic; Humans; Phenotype; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Transferases; Virus Replication

2023
Intestinal Atp8b1 dysfunction causes hepatic choline deficiency and steatohepatitis.
    Nature communications, 2023, Nov-21, Volume: 14, Issue:1

    Topics: Adenosine Triphosphatases; Animals; Child; Choline; Choline Deficiency; Fatty Liver; Female; Gastrointestinal Diseases; Humans; Intestinal Diseases; Lactation; Mice; Phosphatidylcholines; Phospholipid Transfer Proteins

2023
Aging exacerbates high-fat diet-induced steatohepatitis through alteration in hepatic lipid metabolism in mice.
    Journal of gastroenterology and hepatology, 2020, Volume: 35, Issue:8

    Topics: Aging; Animals; Diet, High-Fat; Diglycerides; Disease Progression; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Fatty Liver; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Sirtuin 1

2020
Exogenous Liposomal Ceramide-C6 Ameliorates Lipidomic Profile, Energy Homeostasis, and Anti-Oxidant Systems in NASH.
    Cells, 2020, 05-16, Volume: 9, Issue:5

    Topics: Adenylate Kinase; Animals; Antioxidants; Apoptosis; Cell Proliferation; Ceramides; Choline; Diet; Diglycerides; Energy Metabolism; Fatty Liver; Feeding Behavior; Hematopoietic Stem Cells; Homeostasis; Humans; Lipidomics; Liposomes; Male; Methionine; Mice, Inbred BALB C; NF-E2-Related Factor 2; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphorylation; Protein Subunits; Signal Transduction

2020
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis.
    Molecular systems biology, 2021, Volume: 17, Issue:1

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Gene Expression Profiling; Gene Expression Regulation; Genetic Variation; Glucose; Insulin Resistance; Lipidomics; Male; MAP Kinase Kinase 6; Mice; Nuclear Proteins; Phosphatidylcholines; Triglycerides

2021
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance.
    Nature communications, 2021, 01-11, Volume: 12, Issue:1

    Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Dyslipidemias; Epithelial Cells; Exosomes; Fatty Liver; Feces; Gene Expression Regulation; Glucose Intolerance; Green Fluorescent Proteins; Humans; Insulin; Insulin Resistance; Interleukin-6; Intestines; Lipids; Liver; Macrophage Activation; Mice, Inbred C57BL; Phosphatidylcholines; Receptors, Aryl Hydrocarbon; Signal Transduction; Tetraspanin 30; Tumor Necrosis Factor-alpha; Up-Regulation

2021
Hepatic Steatosis Accompanies Pulmonary Alveolar Proteinosis.
    American journal of respiratory cell and molecular biology, 2017, Volume: 57, Issue:4

    Topics: Animals; Fatty Liver; Female; Liver; Macrophages, Alveolar; Male; Mice; Mice, Knockout; Organ Specificity; Phosphatidylcholines; Pulmonary Alveolar Proteinosis; Pulmonary Alveoli

2017
mTORC1 stimulates phosphatidylcholine synthesis to promote triglyceride secretion.
    The Journal of clinical investigation, 2017, Nov-01, Volume: 127, Issue:11

    Topics: Animals; Cells, Cultured; Fatty Liver; Hepatocytes; Lipogenesis; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylcholines; Triglycerides

2017
FADS2 inhibition in essential fatty acid deficiency induces hepatic lipid accumulation via impairment of very low-density lipoprotein (VLDL) secretion.
    Biochemical and biophysical research communications, 2018, 02-05, Volume: 496, Issue:2

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Fatty Acid Desaturases; Fatty Acids, Unsaturated; Fatty Liver; Lipid Metabolism; Lipoproteins, VLDL; Liver; Male; Mice, Inbred C57BL; Oxidation-Reduction; Phosphatidylcholines

2018
In vitro assessment of nutraceutical compounds and novel nutraceutical formulations in a liver-steatosis-based model.
    Lipids in health and disease, 2018, Feb-05, Volume: 17, Issue:1

    Topics: Choline; Curcumin; Dietary Supplements; Docosahexaenoic Acids; Drug Combinations; Drug Compounding; Drug Synergism; Fatty Liver; Hep G2 Cells; Humans; Lipid Peroxidation; Liver; Phosphatidylcholines; PPAR alpha; PPAR gamma; Silymarin; Vitamin E

2018
Ether-phosphatidylcholine characterized by consolidated plasma and liver lipidomics is a predictive biomarker for valproic acid-induced hepatic steatosis.
    The Journal of toxicological sciences, 2018, Volume: 43, Issue:6

    Topics: Animals; Anticonvulsants; Biomarkers; Fatty Liver; Humans; Lipid Metabolism; Lipids; Liver; Male; Mitochondria, Liver; Phosphatidylcholines; Predictive Value of Tests; Rats, Sprague-Dawley; Valproic Acid

2018
Hepatic methionine homeostasis is conserved in C57BL/6N mice on high-fat diet despite major changes in hepatic one-carbon metabolism.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Amino Acids; Animals; Betaine-Homocysteine S-Methyltransferase; Carbon; Cell Line, Tumor; Cystathionine beta-Synthase; Diet, High-Fat; Fatty Liver; Gene Expression Regulation, Enzymologic; Homeostasis; Lipid Metabolism; Liver; Male; Methionine; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; PPAR alpha; Rats; Sequence Analysis, DNA

2013
Excess S-adenosylmethionine reroutes phosphatidylethanolamine towards phosphatidylcholine and triglyceride synthesis.
    Hepatology (Baltimore, Md.), 2013, Volume: 58, Issue:4

    Topics: Animals; Disease Models, Animal; Fatty Liver; Female; Glycine N-Methyltransferase; Homeostasis; Lipid Metabolism; Liver; Male; Membrane Proteins; Mice; Mice, Knockout; Perilipin-2; Phosphatidylcholines; Phosphatidylethanolamines; S-Adenosylmethionine; Triglycerides

2013
Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression.
    Arteriosclerosis, thrombosis, and vascular biology, 2013, Volume: 33, Issue:7

    Topics: Animals; CD36 Antigens; Cell Line, Tumor; Ceramides; Cholesterol, Dietary; Disease Models, Animal; Down-Regulation; Fatty Liver; Female; Genes, Reporter; Humans; Liver; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Transgenic; Phosphatidylcholines; PPAR gamma; Sphingomyelins; Time Factors; Transfection; Transferases (Other Substituted Phosphate Groups)

2013
Lipidomic analysis of the liver from high-fat diet induced obese mice identifies changes in multiple lipid classes.
    Experimental and molecular pathology, 2014, Volume: 97, Issue:1

    Topics: alpha-Linolenic Acid; Animals; Cholesterol; Decanoic Acids; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Lauric Acids; Lipid Metabolism; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylcholines; Phospholipids; Plasmalogens; Sphingomyelins

2014
Mutations disrupting the Kennedy phosphatidylcholine pathway in humans with congenital lipodystrophy and fatty liver disease.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, Jun-17, Volume: 111, Issue:24

    Topics: 3T3-L1 Cells; Adipose Tissue; Adolescent; Alleles; Animals; Child; Cholesterol, HDL; Choline-Phosphate Cytidylyltransferase; Computational Biology; Fatty Liver; Female; Glycerophospholipids; Humans; Insulin; Lipids; Lipodystrophy; Mice; Mutation; Phenotype; Phosphatidylcholines; Tissue Distribution

2014
Vagus nerve contributes to the development of steatohepatitis and obesity in phosphatidylethanolamine N-methyltransferase deficient mice.
    Journal of hepatology, 2015, Volume: 62, Issue:4

    Topics: Animals; Chemokine CCL2; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Interleukin-10; Liver; Mice; Obesity; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Postoperative Period; Transcription Factor CHOP; Vagotomy; Vagus Nerve

2015
Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase.
    Scientific reports, 2016, Feb-18, Volume: 6

    Topics: Animals; Crystallography, X-Ray; Endothelial Cells; Fatty Liver; Liver; Mice; Mice, Knockout; Oligodendroglia; Organ Specificity; Phosphatidylcholines; Phosphoric Diester Hydrolases; Structure-Activity Relationship; Substrate Specificity

2016
TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
    Nature, 2016, 07-14, Volume: 535, Issue:7611

    Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholesterol, Dietary; Cholesterol, HDL; Diet, High-Fat; Fatty Acids, Unsaturated; Fatty Liver; Female; Gene Expression Regulation; Hepatocytes; Ligands; Lipogenesis; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Liver X Receptors; Male; Mice; Orphan Nuclear Receptors; Phosphatidylcholines; Protein Stability; Proteolysis; Receptors, LDL; Sterol Regulatory Element Binding Protein 1; Ubiquitination

2016
[Effect of polyene phosphatidyl choline on hepatocyte steatosis via PPARα/CPT-1A pathway].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2016, Volume: 24, Issue:4

    Topics: Animals; Carnitine O-Palmitoyltransferase; Fatty Liver; Hepatocytes; Phosphatidylcholines; PPAR alpha; Triglycerides

2016
Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease.
    Alcoholism, clinical and experimental research, 2009, Volume: 33, Issue:4

    Topics: Alcoholism; Animals; Cholesterol Esters; Disease Models, Animal; Ethanol; Fatty Acids; Fatty Liver; Fatty Liver, Alcoholic; Lipid Metabolism; Male; Metabolomics; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Stearoyl-CoA Desaturase; Swine; Swine, Miniature; Triglycerides

2009
Interleukin-6 is associated with liver lipid homeostasis but not with cell death in experimental hepatic steatosis.
    Innate immunity, 2009, Volume: 15, Issue:6

    Topics: Animals; Apoptosis; Cell Membrane Permeability; Cells, Cultured; Choline Deficiency; Diet; Disease Models, Animal; Disease Progression; Electron Transport; Fatty Liver; Hepatocytes; Interleukin-6; Liver; Male; Mitochondria, Liver; Phosphatidylcholines; Rats; Rats, Wistar; Receptors, Interleukin-6; Triglycerides; Tumor Necrosis Factor-alpha

2009
Rapid development of fasting-induced hepatic lipidosis in the American mink (Neovison vison): effects of food deprivation and re-alimentation on body fat depots, tissue fatty acid profiles, hematology and endocrinology.
    Lipids, 2010, Volume: 45, Issue:2

    Topics: Adipose Tissue; Animals; Blood Glucose; Fasting; Fatty Acids, Omega-3; Fatty Liver; Female; Food; Food Deprivation; Hematologic Tests; Leptin; Lipid Metabolism; Liver; Male; Mink; Phosphatidylcholines; Phospholipids; Sex Factors; Triglycerides; Weight Loss

2010
Expression of perilipin and adipophilin in nonalcoholic fatty liver disease; relevance to oxidative injury and hepatocyte ballooning.
    Journal of atherosclerosis and thrombosis, 2009, Volume: 16, Issue:6

    Topics: Adult; Biopsy; Carrier Proteins; Fatty Liver; Female; Gene Expression Regulation; Hepatocytes; Humans; Lipid Metabolism; Lipids; Male; Membrane Proteins; Middle Aged; Oxidative Stress; Peptides; Perilipin-1; Perilipin-2; Phosphatidylcholines; Phosphoproteins

2009
Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity.
    The Journal of biological chemistry, 2010, Jul-16, Volume: 285, Issue:29

    Topics: Animals; Betaine; Choline; Diet; Dietary Fats; Dietary Supplements; Energy Metabolism; Fatty Liver; Feeding Behavior; Insulin Resistance; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; Phenotype; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Weight Gain

2010
Hydrogenated phosphatidylcholine supplementation reduces hepatic lipid levels in mice fed a high-fat diet.
    Atherosclerosis, 2010, Volume: 213, Issue:1

    Topics: Animal Feed; Animals; Cholesterol; Dietary Fats; Fatty Liver; Gene Expression Regulation; Lipids; Liver; Male; Mice; Mice, Inbred C57BL; Models, Biological; Phosphatidylcholines; Phospholipids; Spectrometry, Mass, Electrospray Ionization; Sphingomyelins

2010
Hepatocellular carcinomas can develop in simple fatty livers in the setting of oxidative stress.
    Pathology, 2011, Volume: 43, Issue:2

    Topics: Aged; Carcinoma, Hepatocellular; Disease-Free Survival; Fatty Liver; Hepatectomy; Humans; Liver; Liver Neoplasms; Male; Oxidative Stress; Phosphatidylcholines; Tomography, X-Ray Computed; Treatment Outcome

2011
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.
    Nature, 2011, May-25, Volume: 474, Issue:7352

    Topics: Animals; Bile Acids and Salts; Blood Glucose; Cell Line; Disease Models, Animal; Fatty Liver; HeLa Cells; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Protein Binding; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Triglycerides

2011
Metabolism: A lipid for fat disorders.
    Nature, 2011, Jun-22, Volume: 474, Issue:7352

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Bile Acids and Salts; Fatty Liver; Humans; Insulin Resistance; Liver; Mice; Phosphatidylcholines; Receptors, Cytoplasmic and Nuclear; Signal Transduction

2011
Phosphatidylcholine protects against steatosis in mice but not non-alcoholic steatohepatitis.
    Biochimica et biophysica acta, 2011, Volume: 1811, Issue:12

    Topics: Adenoviridae; Animals; Betaine; Ceramides; Choline-Phosphate Cytidylyltransferase; Cytidine Diphosphate Choline; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Female; Genetic Predisposition to Disease; Genetic Vectors; Lipotropic Agents; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Triglycerides

2011
Hepatic ratio of phosphatidylcholine to phosphatidylethanolamine predicts survival after partial hepatectomy in mice.
    Hepatology (Baltimore, Md.), 2012, Volume: 55, Issue:4

    Topics: Animals; Choline; Choline-Phosphate Cytidylyltransferase; Dietary Fats; Dietary Supplements; Disease Models, Animal; Disease Progression; Fatty Liver; Hepatectomy; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Predictive Value of Tests; Survival Rate

2012
[Importance of phospholipids in ER stress and fatty liver disease].
    Medecine sciences : M/S, 2012, Volume: 28, Issue:1

    Topics: Animals; Biological Transport, Active; Calcium; Choline-Phosphate Cytidylyltransferase; Endoplasmic Reticulum Stress; Fatty Liver; Homeostasis; Humans; Membrane Lipids; Mice; Mice, Obese; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipids; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Triglycerides; Unfolded Protein Response

2012
Lipidomic analysis of the liver identifies changes of major and minor lipid species in adiponectin deficient mice.
    Experimental and molecular pathology, 2013, Volume: 94, Issue:2

    Topics: Adiponectin; Animals; Bile Acids and Salts; Cholesterol; Cholesterol Esters; Cytochromes; Dietary Fats; Fatty Acids; Fatty Liver; Glucosylceramides; Lipid Metabolism; Lipogenesis; Liver; Male; Mice; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Stearoyl-CoA Desaturase; Sterol Regulatory Element Binding Protein 2; Triglycerides; Up-Regulation

2013
The membrane lipid phosphatidylcholine is an unexpected source of triacylglycerol in the liver.
    The Journal of biological chemistry, 2012, Jul-06, Volume: 287, Issue:28

    Topics: Animals; Cell Line, Tumor; Cells, Cultured; Choline-Phosphate Cytidylyltransferase; Fatty Liver; Female; Humans; Isoenzymes; Lipoproteins, HDL; Liver; Male; Membrane Lipids; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Scavenger Receptors, Class B; Triglycerides; Tritium

2012
A brief history of choline.
    Annals of nutrition & metabolism, 2012, Volume: 61, Issue:3

    Topics: Acetylcholine; Animals; Bile; Choline; Dogs; Fatty Liver; History, 19th Century; History, 20th Century; History, 21st Century; Humans; Lecithins; Liver; Neurotransmitter Agents; Nutritive Value; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Rats

2012
[Use of essentiale with cholagogue in fatty liver complicated by cholecystitis for lowering the lithogenic properties of bile].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:3

    Topics: Adult; Cholagogues and Choleretics; Cholecystitis; Cholelithiasis; Drug Therapy, Combination; Fatty Liver; Female; Humans; Male; Middle Aged; Phosphatidylcholines

2002
[Treatment of fatty liver hypertrophy with lecithin].
    Deutsche medizinische Wochenschrift (1946), 1953, Feb-20, Volume: 78, Issue:8

    Topics: Fatty Liver; Humans; Hypertrophy; Lecithins; Liver Diseases; Phosphatidylcholines

1953
[Therapy of the fatty liver with lipotropic substances].
    Medizinische Klinik, 1956, Jan-13, Volume: 51, Issue:2

    Topics: Choline; Fatty Liver; Humans; Lecithins; Lipotropic Agents; Liver Diseases; Methionine; Phosphatidylcholines

1956
[Importance of lecithin in fat metabolism & experimental fatty liver in rat].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1958, Volume: 18, Issue:4

    Topics: Animals; Carbon Tetrachloride; Choline; Choline Deficiency; Fatty Liver; Lecithins; Lipid Metabolism; Lipotropic Agents; Phosphatidylcholines; Rats

1958
PHOSPHOLIPID PATTERNS IN LIVERS ACCUMULATING FAT.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Cerium; Chromatography; Fatty Liver; Lecithins; Phosphatidylcholines; Phospholipids; Rats; Research; Toxicology

1964
CHYLOUS ASCITES IN NEWBORN MICE.
    Journal of medical genetics, 1964, Volume: 1, Issue:1

    Topics: Animals; Animals, Newborn; Breeding; Cholesterol; Chyle; Chylous Ascites; Congenital Abnormalities; Diaphragm; Fatty Acids; Fatty Liver; Genetics; Glycerides; Humans; Intestine, Small; Jejunum; Lecithins; Lymphatic System; Mesentery; Mice; Pancreas; Pathology; Phosphatidylcholines; Phosphatidylethanolamines; Research; Rodent Diseases; Sphingomyelins

1964
Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes.
    Diabetes, 2005, Volume: 54, Issue:6

    Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Hypoglycemic Agents; Liver; Male; Mice; Mice, Congenic; Pharmacogenetics; Phenotype; Phosphatidylcholines; Rosiglitazone; Thiazolidinediones

2005
Localization of oxidized phosphatidylcholine in nonalcoholic fatty liver disease: impact on disease progression.
    Hepatology (Baltimore, Md.), 2006, Volume: 43, Issue:3

    Topics: Aged; Apoptosis; Disease Progression; Fatty Liver; Female; Hepatocytes; Humans; Iron; Lipid Peroxidation; Male; Middle Aged; Neutrophil Infiltration; Oxidative Stress; Phosphatidylcholines

2006
The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis.
    Cell metabolism, 2006, Volume: 3, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Cell Membrane; Choline Deficiency; Disease Progression; Fatty Liver; Hepatocytes; Liver Failure, Acute; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines

2006
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism.
    Vascular pharmacology, 2006, Volume: 45, Issue:1

    Topics: Animals; Cardiolipins; Cardiovascular System; Choline-Phosphate Cytidylyltransferase; Crosses, Genetic; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred NOD; Mice, Obese; Mitochondria, Heart; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; PPAR gamma; Rosiglitazone; Thiazolidinediones

2006
A choline-deficient diet exacerbates fatty liver but attenuates insulin resistance and glucose intolerance in mice fed a high-fat diet.
    Diabetes, 2006, Volume: 55, Issue:7

    Topics: Animals; Blood Glucose; Choline Deficiency; Dietary Fats; Disease Models, Animal; Energy Intake; Fatty Liver; Glucose Intolerance; Kinetics; Liver; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Phosphatidylcholines; RNA, Messenger; Weight Gain

2006
Choline cannot be replaced by propanolamine in mice.
    Biochimica et biophysica acta, 2007, Volume: 1771, Issue:4

    Topics: Animals; Choline; Choline Deficiency; Fatty Liver; Liver; Methionine; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Propanolamines; Triglycerides

2007
Metabolomics (liver and blood profiling) in a mouse model in response to fasting: a study of hepatic steatosis.
    Biochimica et biophysica acta, 2007, Volume: 1771, Issue:10

    Topics: Animals; Blood; Cholesterol Esters; Chromatography, High Pressure Liquid; Disease Models, Animal; Fatty Liver; Food Deprivation; Lipoproteins, LDL; Liver; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phospholipids; Triglycerides

2007
Phosphatidylcholine could have a key role in the pathogenesis of steatohepatitis - Reply.
    Journal of hepatology, 2007, Volume: 47, Issue:6

    Topics: Fatty Liver; Humans; Phosphatidylcholines

2007
Quantitative profiling of phosphatidylcholine and phosphatidylethanolamine in a steatosis/fibrosis model of rat liver by nanoflow liquid chromatography/tandem mass spectrometry.
    Journal of chromatography. A, 2008, Jun-13, Volume: 1194, Issue:1

    Topics: Animals; Chromatography, Liquid; Disease Models, Animal; Fatty Liver; Liver Cirrhosis; Male; Phosphatidylcholines; Phosphatidylserines; Rats; Rats, Sprague-Dawley; Reference Standards; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2008
Modification of aortic atheroma and fatty liver in cholesterol-fed rabbits by intravenous injection of saturated and polyunsaturated lecithins.
    The Journal of pathology and bacteriology, 1967, Volume: 94, Issue:1

    Topics: Animals; Arteriosclerosis; Cholesterol; Fats, Unsaturated; Fatty Liver; Male; Phosphatidylcholines; Rabbits

1967
[Polyunsaturated phosphatidylcholine in the treatment of hepatic steatosis].
    La Clinica terapeutica, 1983, Nov-30, Volume: 107, Issue:4

    Topics: Adolescent; Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Fatty Liver; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Vitamin B Complex

1983
Pathogenesis of hepatic steatosis in the parenterally fed rat.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:5

    Topics: Animals; Body Weight; Fatty Acids; Fatty Liver; Lipid Metabolism; Lipids; Liver; Male; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Phosphatidylcholines; Polyethylene Glycols; Rats; Triglycerides

1984
Fatty liver due to disproportionally added methionine to a low soybean diet and lipotropic action of phosphatides in rats.
    The Journal of nutrition, 1980, Volume: 110, Issue:3

    Topics: Animals; Apolipoproteins; Biological Transport; Cholesterol; Fatty Liver; Glycine max; Insulin; Lipid Metabolism; Methionine; Phosphatidylcholines; Phospholipids; Plant Proteins, Dietary; Rats; Triglycerides

1980
[Plasma proteins in patients with liver steatosis and the effect of treatment of essential phospholipids].
    Bratislavske lekarske listy, 1996, Volume: 97, Issue:10

    Topics: Blood Proteins; Fatty Liver; Female; Humans; Male; Middle Aged; Phosphatidylcholines

1996
[Positive effects of essential phospholipids and improvement of life style in patients with toxic liver injury].
    Bratislavske lekarske listy, 1998, Volume: 99, Issue:2

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Male; Middle Aged; Occupational Diseases; Phosphatidylcholines; Temperance

1998
The effect of a combined dietary treatment with cholesterol and cholic acid on the lipid metabolism of geese at low or high choline concentrations.
    Archiv fur Tierernahrung, 1999, Volume: 52, Issue:3

    Topics: Animals; Body Weight; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Cholic Acid; Choline; Chromatography, Gas; Fatty Liver; Female; Geese; Lipid Metabolism; Liver; Male; Muscle, Skeletal; Phosphatidylcholines; Random Allocation; Triglycerides

1999
[Effect of the transcranial electrical stimulation of the endorphinergic brain structures on the functional activity of hepatocytes after toxic exposure].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2000, Volume: 86, Issue:11

    Topics: Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Electric Stimulation; Endorphins; Ethylene Dichlorides; Fatty Liver; Hepatocytes; Liver Function Tests; Male; Naloxone; Narcotic Antagonists; Phosphatidylcholines; Protective Agents; Rats; Rats, Wistar

2000
Effect of inositol, lecithin, vitamins (B12 with choline and E), and iodinated casein on induced fatty liver-hemorrhagic syndrome in laying chickens.
    Poultry science, 1975, Volume: 54, Issue:4

    Topics: Animal Feed; Animals; Caseins; Chickens; Choline; Eggs; Fatty Liver; Female; Hemorrhage; Inositol; Iodine; Lipids; Lipotropic Agents; Liver; Oviposition; Phosphatidylcholines; Poultry Diseases; Syndrome; Vitamin B 12; Vitamin E; Vitamins

1975
Sex difference in the development of fatty liver by orotic acid.
    Japanese journal of pharmacology, 1975, Volume: 25, Issue:3

    Topics: Acetates; Animals; Fatty Liver; Female; Lipoproteins, LDL; Liver; Male; Methionine; Orotic Acid; Phosphatidylcholines; Proteins; Rats; Sex Factors

1975
[Phosphatidylcholines and fatty liver. Therapeutic effects in the rat with ethyl alcohol and carbon tetrachloride intoxication].
    Medecine & chirurgie digestives, 1977, Volume: 6, Issue:2

    Topics: Alcoholic Intoxication; Animals; Carbon Tetrachloride Poisoning; Fatty Liver; Female; Humans; Male; Phosphatidylcholines

1977
[Phosphatidylcholines and fatty liver. Therapeutic effect in the swine with ethyl alcohol or carbon tetrachloride poisoning].
    Medecine & chirurgie digestives, 1978, Volume: 7, Issue:3

    Topics: Alcoholic Intoxication; Animals; Carbon Tetrachloride Poisoning; Fatty Liver; Female; Humans; Liver; Male; Phosphatidylcholines; Swine

1978
Influence of phospholipids on liver damage. II. Changes in lipid content and synthesis after liver damage with carbontetrachloride and other agents.
    Acta hepato-gastroenterologica, 1975, Volume: 22, Issue:4

    Topics: Acetates; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA; Fatty Liver; Hepatectomy; Lipids; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Orotic Acid; Phosphatidylcholines; Phospholipids; Rats; Thymus Gland; X-Rays

1975
[Effect of subcutaneous administration of liposomes on the functional state of the organs and systems in experimental animals].
    Vestnik Akademii meditsinskikh nauk SSSR, 1990, Issue:6

    Topics: Animals; Cholesterol; Dose-Response Relationship, Drug; Fatty Liver; Female; Injections, Subcutaneous; Lipid Peroxidation; Liposomes; Liver; Male; Phosphatidylcholines; Rabbits; Rats

1990
Liver phosphatidylcholine hydroperoxidation provoked by ethionine-containing choline-deficient diet in mice.
    Lipids, 1990, Volume: 25, Issue:9

    Topics: Animals; Body Weight; Choline Deficiency; Ethionine; Fatty Liver; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred Strains; Organ Size; Phosphatidylcholines

1990
Comparison of the thin layer chromatography/flame ionization detection system with other methods for the quantitative analysis of liver lipid contents in alcohol-fed rats and controls.
    Lipids, 1985, Volume: 20, Issue:8

    Topics: Animals; Cholesterol; Cholesterol Esters; Chromatography, Gas; Chromatography, Thin Layer; Ethanol; Fatty Liver; Flame Ionization; Lipids; Liver; Phosphatidylcholines; Phospholipids; Rats; Triglycerides

1985
Essential fatty acid studies in primates linolenic acid requirements of capuchins.
    Journal of medical primatology, 1973, Volume: 2, Issue:3

    Topics: Adrenal Glands; Alopecia; Animals; Deficiency Diseases; Diet; Erythrocytes; Fatty Acids, Essential; Fatty Liver; Haplorhini; Linoleic Acids; Linolenic Acids; Linseed Oil; Lipids; Liver; Monkey Diseases; Nutritional Requirements; Oils; Phosphatidylcholines; Phosphatidylethanolamines; Skin Diseases; Triglycerides; Zea mays

1973
Lipid composition of subcellular fractions in carbon tetrachloride induced fatty liver.
    Indian journal of biochemistry, 1969, Volume: 6, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Cholesterol; Cytoplasm; Fatty Liver; Lipid Metabolism; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Sphingomyelins

1969
Proceedings: Subcellular distribution of phospholipids in rare-earth induced liver damage.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Fatty Liver; Female; Lipoproteins; Liver; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Praseodymium; Rats; Surface-Active Agents; Time Factors; Triglycerides

1974
Phospholipid changes during hepatic injury caused by carbon tetrachloride.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Chromatography, Ion Exchange; Fats, Unsaturated; Fatty Acids; Fatty Liver; Glycerol; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingomyelins

1967
Alteration in liver lipid and lipid fatty acid composition after partial hepatectomy in the rat.
    Experimental and molecular pathology, 1968, Volume: 8, Issue:2

    Topics: Adipose Tissue; Animals; Azoles; Epididymis; Ergotamine; Fatty Acids; Fatty Acids, Nonesterified; Fatty Liver; Hepatectomy; Linoleic Acids; Lipid Metabolism; Liver Regeneration; Male; Nicotinic Acids; Oleic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Triglycerides

1968
[Study of the hepatic phospholipids in induced steatosis by carbon tetrachloride].
    Archives des sciences physiologiques, 1968, Volume: 22, Issue:1

    Topics: Animals; Carbon Tetrachloride; Chromatography, Thin Layer; Fatty Acids; Fatty Liver; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingomyelins; Triglycerides

1968
Cholelithiasis in rabbits: effects of bile constituents and hormones on dissolution of gallstones.
    American journal of veterinary research, 1969, Volume: 30, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Bile Acids and Salts; Cholelithiasis; Cortisone; Fatty Liver; Glycine; Phosphatidylcholines; Rabbits; Taurine; Thyroid Hormones

1969
D-galactosamine induced fatty liver. II. Analyses of hepatic lipid compositions.
    Lipids, 1973, Volume: 8, Issue:10

    Topics: Animals; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Fatty Liver; Female; Galactosamine; Liver; Lysophosphatidylcholines; Optical Rotation; Organ Size; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingomyelins; Triglycerides

1973
Incorporation of palmitate-1-14C into liver lipids of rats fed millet (Sorghum vulgarie) at different protein levels.
    Nutrition and metabolism, 1974, Volume: 17, Issue:1

    Topics: Animal Nutritional Physiological Phenomena; Animals; Carbon Radioisotopes; Cholesterol; Dietary Proteins; Edible Grain; Fatty Acids; Fatty Liver; Lipid Metabolism; Lipids; Liver; Male; Organ Size; Palmitic Acids; Panicum; Phosphatidylcholines; Phosphatidylethanolamines; Plant Proteins; Rats; Triglycerides

1974
[Phospholipid pattern in acute and chronic liver diseases (author's transl)].
    Klinische Wochenschrift, 1974, Aug-15, Volume: 52, Issue:16

    Topics: Acute Disease; Adult; Chromatography, Thin Layer; Chronic Disease; Fatty Liver; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Lysophosphatidylcholines; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sphingomyelins

1974
The effect of acute ethanol ingestion on in vitro metabolism of choline and ethanol derivatives in rat liver.
    Biochemical pharmacology, 1974, Dec-01, Volume: 23, Issue:23

    Topics: Animals; Choline; Diet; Ethanol; Ethanolamines; Fatty Liver; Female; Lipids; Liver; Membranes; Methylation; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Triglycerides

1974
Cholelithiasis in mice: effects of different chemicals upon formation and prevention of gallstones.
    The Journal of surgical research, 1974, Volume: 16, Issue:2

    Topics: Alcohols; Animals; Ascorbic Acid; Cholelithiasis; Cholesterol; Cholesterol, Dietary; Cholic Acids; Fatty Liver; Female; Guanidines; Male; Mice; Neomycin; Pectins; Phosphatidylcholines; Sulfonamides

1974
A quantitative morphological analysis of ethanol effect upon rat liver.
    Gastroenterology, 1972, Volume: 62, Issue:5

    Topics: Animals; Choline; Endoplasmic Reticulum; Ethanol; Fatty Liver; Glycogen; Golgi Apparatus; Lipids; Liver; Lysosomes; Male; Microscopy, Electron; Mitochondria, Liver; Mixed Function Oxygenases; Phosphatidylcholines; Phospholipids; Rats; Rats, Inbred Strains; Triglycerides

1972
Fatty liver induction: inverse relationship between hepatic neutral lipid accumulation and dietary polyunsaturated fatty acids in orotic acid-fed rats.
    Journal of lipid research, 1972, Volume: 13, Issue:1

    Topics: Aniline Compounds; Animals; Dietary Fats; Fatty Acids, Essential; Fatty Liver; Female; Hexobarbital; Linoleic Acids; Lipids; Liver; Male; Microsomes, Liver; Orotic Acid; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Protein Biosynthesis; Rats

1972
Role of lipoperoxidation in early choline deficiency.
    Experimental and molecular pathology, 1970, Volume: 12, Issue:1

    Topics: Age Factors; Animals; Choline Deficiency; Fatty Liver; Lipid Metabolism; Male; Mitochondria, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Spectrum Analysis; Triglycerides

1970
Mode of action of choline. V. Sequential changes in hepatic and serum lipids of choline-deficient rats.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:11

    Topics: Animals; Choline; Deficiency Diseases; Fatty Liver; Liver; Male; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Time Factors; Triglycerides

1970
Phospholipid fatty liver: a proposal of a new concept and its electron microscopical study.
    Acta pathologica japonica, 1970, Volume: 20, Issue:4

    Topics: Acute Disease; Biopsy; Cholesterol; Chromatography, Thin Layer; Chronic Disease; Cytoplasm; Fatty Acids, Nonesterified; Fatty Liver; Female; Histocytochemistry; Humans; Lipids; Liver; Lysophosphatidylcholines; Microscopy, Electron; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Sphingomyelins; Triglycerides

1970
[Therapeutic use of oxygen in ischemic heart disease].
    Kardiologiia, 1967, Volume: 7, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Animals; Blood Gas Analysis; Cholesterol; Coronary Disease; Erythrocytes; Fatty Liver; Female; Hematocrit; Humans; Hypertension; Lipidoses; Lipoproteins; Liver Circulation; Male; Middle Aged; Myocardial Infarction; Oxygen Inhalation Therapy; Phosphatidylcholines; Polycythemia; Rabbits; Respiratory Function Tests

1967
[Effect of "essential" phospholipids on liver changes after chronic ethyl alcohol- and allylisosulfocyanate intoxication in albino rats].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:11

    Topics: Animals; Cholesterol; Cyanates; Ethanol; Fatty Acids; Fatty Liver; Liver; Male; Methods; Phosphatidylcholines; Phospholipids; Rats

1967
Red cell lipids in Zieve's syndrome: their relation to hemolysis and to red cell osmotic fragility.
    The Journal of laboratory and clinical medicine, 1968, Volume: 72, Issue:4

    Topics: Alcoholism; Anemia, Hemolytic; Cholesterol; Erythrocytes; Fatty Liver; Hemolysis; Humans; Hyperlipidemias; Jaundice; Lipids; Liver Cirrhosis; Osmotic Fragility; Phosphatidylcholines; Phospholipids

1968
Studies on liver phosphatidyl cholines: I. Effects of fatty liver induction on phosphatidyl cholines from liver mitochondria and microsomes.
    Lipids, 1969, Volume: 4, Issue:1

    Topics: Animals; Body Weight; Carbon Tetrachloride; Choline Deficiency; Chromatography, Gas; Chromatography, Thin Layer; Diet; Ethionine; Fatty Acids; Fatty Liver; Female; Liver; Microsomes; Mitochondria, Liver; Oils; Organ Size; Phosphatidylcholines; Phospholipids; Protein Deficiency; Proteins; Rats; Zea mays

1969
[On methylation processes in metabolism].
    Die Medizinische Welt, 1969, Feb-22, Volume: 8

    Topics: Biochemical Phenomena; Biochemistry; Choline; Dietary Fats; Epinephrine; Fatty Liver; Humans; Mescaline; Metabolism; Methionine; Methylation; Norepinephrine; Phenethylamines; Phosphatidylcholines; Schizophrenia

1969
Studies on phospholipid metabolism in choline deficient fatty liver.
    Journal of biochemistry, 1969, Volume: 65, Issue:1

    Topics: Animals; Carbon Isotopes; Choline; Choline Deficiency; Chromatography; Fatty Acids; Fatty Liver; Female; Male; Methionine; Methylation; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Proteins; Rats

1969
Metabolism of phosphorylcholine and lecithin in normal and choline-deficient rats.
    Biochimica et biophysica acta, 1969, Mar-04, Volume: 176, Issue:2

    Topics: Animals; Carbon Isotopes; Choline; Choline Deficiency; Fatty Liver; Lipid Metabolism; Liver; Male; Methionine; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Rats

1969
Liver phospholipids of rats deprived of dietary choline.
    Canadian journal of biochemistry, 1969, Volume: 47, Issue:3

    Topics: Animals; Arachidonic Acids; Body Weight; Choline; Chromatography, Gas; Fatty Acids; Fatty Liver; Food Deprivation; Liver; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Venoms

1969
Effect of oral polyunsaturated lecithin on the development of atheroma and fatty liver in the cholesterol-fed rabbit.
    The Journal of pathology, 1969, Volume: 97, Issue:1

    Topics: Animals; Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Diet, Atherogenic; Fatty Liver; Injections, Intravenous; Intestinal Absorption; Male; Phosphatidylcholines; Rabbits

1969
Relation of serum lipids and lipoproteins to fatty liver in kwashiorkor.
    The American journal of clinical nutrition, 1969, Volume: 22, Issue:5

    Topics: Biopsy; Blood Protein Electrophoresis; Child; Child, Preschool; Cholesterol; Chromatography, Thin Layer; Diet Therapy; Dietary Fats; Dietary Proteins; Electrophoresis; Fatty Liver; Humans; Kwashiorkor; Lipoproteins; Phosphatidylcholines; Phospholipids; Serum Albumin; Sphingomyelins; Time Factors; Triglycerides

1969
Alterations in phospholipid metabolism induced by ethanol administration.
    Biochimica et biophysica acta, 1965, Jun-01, Volume: 98, Issue:3

    Topics: Alkylation; Animals; Choline; Chromatography, Thin Layer; Ethanol; Fatty Liver; Formates; In Vitro Techniques; Liver; Methionine; Phosphatidylcholines; Phospholipids; Rats; Serine

1965
The effects of choline deficiency and choline re-feeding upon the metabolism of plasma and liver lipids.
    Canadian journal of biochemistry, 1966, Volume: 44, Issue:1

    Topics: Amino Alcohols; Animals; Choline; Deficiency Diseases; Fatty Liver; Lipid Metabolism; Liver; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Triglycerides

1966