Compounds > phosphatidylcholines
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phosphatidylcholines and Insulin Sensitivity

phosphatidylcholines has been researched along with Insulin Sensitivity in 48 studies

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (2.08)18.2507
2000's6 (12.50)29.6817
2010's32 (66.67)24.3611
2020's9 (18.75)2.80

Authors

AuthorsStudies
D'Amore, S; Griffin, JL; Hall, Z; Herrera-Marcos, LV; Jenkins, B; Kay, R; Koulman, A; Mocciaro, G; Moschetta, A; Murgia, A; Murray, A; Neun, S; Palasciano, G; Palma-Duran, SA; Reimann, F; Sabbà, C; Sowton, AP; Suppressa, P; Vacca, M1
Aouadi, M; Bidault, G; Çubuk, C; Dopazo, J; Jenkins, B; Koulman, A; Morgantini, C; Petkevicius, K; Serlie, MJ; Vidal-Puig, A; Virtue, S1
Bruno, RS; Cichon, MJ; Kopec, RE; Li, J; Riedl, KM; Sasaki, GY1
Choi, HJ; Jeon, HJ; Kim, BJ; Kim, JM; Kim, YJ; Lee, HS; Oh, T; Yu, HY; Yun, JH1
Chen, C; Chen, X; Liu, P; Peng, C; Yan, B; Zhu, L; Zhu, W1
Li, Z; Liu, Y; Tian, Y; Wang, J; Wang, Y; Xu, J; Xue, C2
Chung, YH; Jeong, JH; Jung, TW; Park, ES; Park, J1
Bönhof, GJ; Knebel, B; Kotzka, J; Roden, M; Straßburger, K; Strom, A; Szendroedi, J; Ziegler, D1
Bjellaas, T; Chella Krishnan, K; Dalen, KT; Drevon, CA; Gundersen, TE; Hui, ST; Lang, J; Lusis, AJ; Mehrabian, M; Meng, Y; Norheim, F; Pan, C; Parks, BW; Péterfy, M; Reue, K; Seldin, MM; Vergnes, L; Ward, JA1
Bohler, HCL; Dryden, GW; Han, X; Kumar, A; Lei, C; McClain, CJ; Merchant, ML; Mu, J; Park, JW; Qin, C; Qiu, X; Sriwastva, MK; Sundaram, K; Teng, Y; Wang, B; Xu, F; Xu, Z; Yan, J; Zhang, HG; Zhang, L; Zhang, S; Zhang, X1
Du, L; Gao, X; Li, D; Li, K; Randell, E; Zhang, H1
Dixon, JB; Eikelis, N; Grima, MT; Huynh, K; Lambert, EA; Lambert, GW; Meikle, PJ; Mundra, PA; Phillips, S; Sari, CI; Schlaich, MP; Straznicky, NE; Weir, JM1
Burda, M; Macášek, J; Staňková, B; Tvrzická, E; Vecka, M; Žák, A; Zeman, M1
Clifton, PM; Keogh, JB; Meikle, PJ; Turner, KM1
Vance, DE1
Aker, A; Birkeland, KI; Drevon, CA; Gulseth, HL; Gundersen, TE; Holen, T; Langleite, TM; Lee, S; Norheim, F1
Carlson, OD; Chia, CW; Fabbri, E; Ferrucci, L; Gonzalez-Freire, M; Khadeer, M; Moaddel, R; Salem, N; Semba, RD; Sun, K; Zhang, P1
Feng, H; Gui, L; Li, N; Liu, Z; Ruan, M; Wan, JM; Wang, H; Zhang, H; Zhang, S1
Lozano, CD; Méndez-Huerta, MA; Ruiz-Argüelles, A; Ruiz-Argüelles, GJ1
Capel, F; Jouve, C; Pinel, A; Rigaudière, JP1
Lundell, LS; Massart, J; Näslund, E; Nylén, C; Zierath, JR1
Curtis, JM; Fullerton, MD; Galleguillos, D; Jacobs, RL; LeBlond, ND; Lingrell, S; McCloskey, N; Sipione, S; van der Veen, JN; Vance, DE; Zhao, YY1
Fan, B; Guo, XL; Li, JJ; Zhang, P; Zheng, ZS1
Bain, JR; Lowe, WL1
Arduini, A; Lopaschuk, GD; Ussher, JR1
He, J; Howard, BV; Hyun, N; Jones, D; Lee, ET; Tran, VT; Uppal, K; Yu, T; Zeng, D; Zhao, J; Zhu, Y1
Jacobs, RL; Lingrell, S; Tasseva, G; van der Veen, JN; Vance, DE; Vance, JE1
Chamulitrat, W; Deng, X; Jiao, L; Liebisch, G; Schmitz, G; Stremmel, W; Tuma-Kellner, S; Utaipan, T; Wang, J1
Bacon, SD; Bergman, BC; Brozinick, JT; Bui, HH; D'Alessandro, A; Hansen, KC; Kerege, AA; Kiseljak-Vassiliades, K; Kuo, MS; Nemkov, T; Newsom, SA; Perreault, L; Sanders, P; Siddall, P; Strauss, AN; Thomas, M; Wei, T1
Hong, MJ; Hur, HJ; Kim, MS; Kim, SH; Kwon, DY; Park, HS; Park, SJ; Sung, MJ1
Gruber, L; Humer, E; Khol-Parisini, A; Metzler-Zebeli, BU; Zebeli, Q1
Cao, G; Dyck, JR; Jacobs, RL; Kennedy, BP; Koonen, DP; Kuo, MS; Lingrell, S; Peake, DA; Proctor, SD; Sletten, T; Su, B; Vance, DE; Zhao, Y1
Celinski, K; Cichoz-Lach, H; Konturek, PC; Konturek, SJ; Slomka, M1
Cenarro, A; Civeira, F; Cofán, M; Mateo-Gallego, R; Ortega, E; Ros, E; Sala-Vila, A1
Busby, SA; Griffin, PR; Lee, JM; Lee, YK; Mamrosh, JL; Moore, DD; Ortlund, EA; Pathak, MC1
Ingraham, HA1
Adamski, J; Boeing, H; Drogan, D; Floegel, A; Fritsche, A; Häring, HU; Hrabě de Angelis, M; Illig, T; Joost, HG; Mühlenbruch, K; Peters, A; Pischon, T; Prehn, C; Roden, M; Schulze, MB; Stefan, N; Wang-Sattler, R; Yu, Z1
Zeisel, SH1
Adam, KP; Adamski, J; Camastra, S; Ferrannini, E; Gall, WE; Groop, L; Kastenmüller, G; Lyssenko, V; Mari, A; Milburn, MV; Nannipieri, M; Natali, A; Tuomi, T1
Jirak, R; Macasek, J; Tvrzicka, E; Vareka, T; Vecka, M; Zak, A; Zeman, M1
Bitsanis, D; Crawford, MA; Ghebremeskel, K; Lowy, C; Min, Y; Thomas, B1
Brosnan, JT; Brosnan, ME; Hall, B; Ratnam, S; Wijekoon, EP; Zeisel, SH1
Kawakami, Y; Kokusho, Y; Komaru, T; Koshida, R; Miyazawa, T; Nakayama, M; Shimokawa, H; Shirato, K; Takahashi, K; Takeda, M; Takeda, S; Yamaguchi, N1
Betteridge, DJ; Cooper, MB; Freeman, DJ; Griffin, BA; Hales, CN; Ling, KL; Packard, CJ; Shepherd, J; Tan, KC1
Azzam, A; Blackard, WG; Clore, JN; Gill, R; Harris, PA; Li, J; Rizzo, WB; Zuelzer, W1
Hori, H; Ohkura, K1
Donner, M; Drouin, P; Meyer, L; Younsi, M; Zeghari, N; Ziegler, O1

Reviews

3 review(s) available for phosphatidylcholines and Insulin Sensitivity

ArticleYear
The mechanisms of lysophosphatidylcholine in the development of diseases.
    Life sciences, 2020, Apr-15, Volume: 247

    Topics: Animals; Arteries; Atherosclerosis; Blood Glucose; Cardiovascular Diseases; Cell Movement; Cytokines; Endothelial Cells; Humans; Inflammation; Insulin Resistance; Lipoproteins, LDL; Lymphocytes; Lysophosphatidylcholines; Macrophages; Myocytes, Smooth Muscle; Neoplasms; Nervous System Diseases; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A2; Pyroptosis; Receptors, G-Protein-Coupled; Toll-Like Receptors

2020
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
    Atherosclerosis, 2013, Volume: 231, Issue:2

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Insulin Resistance; Intestines; Liver; Methylamines; Mice; Microbiota; Muscle, Skeletal; Myocardial Ischemia; Phosphatidylcholines; Risk

2013
Metabolic crosstalk between choline/1-carbon metabolism and energy homeostasis.
    Clinical chemistry and laboratory medicine, 2013, Mar-01, Volume: 51, Issue:3

    Topics: Animals; Betaine; Carbon; Choline; Energy Metabolism; Humans; Insulin Resistance; Metabolic Networks and Pathways; Mitochondria; Obesity; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase

2013

Trials

4 trial(s) available for phosphatidylcholines and Insulin Sensitivity

ArticleYear
Changes in Lipids and Inflammatory Markers after Consuming Diets High in Red Meat or Dairy for Four Weeks.
    Nutrients, 2017, Aug-17, Volume: 9, Issue:8

    Topics: Adult; Biomarkers; Body Mass Index; C-Reactive Protein; Cholesterol; Dairy Products; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Female; Humans; Inflammation; Insulin Resistance; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Red Meat; Triglycerides; Tumor Necrosis Factor-alpha

2017
Novel metabolic markers for the risk of diabetes development in American Indians.
    Diabetes care, 2015, Volume: 38, Issue:2

    Topics: Adult; Biomarkers; Biphenyl Compounds; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Indians, North American; Insulin Resistance; Isoflavones; Logistic Models; Male; Metabolomics; Oligopeptides; Phosphatidylcholines; Prospective Studies; Risk Factors

2015
The effects of L-tryptophan and melatonin on selected biochemical parameters in patients with steatohepatitis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:5

    Topics: Adult; Antioxidants; Cytokines; Fatty Liver; Female; gamma-Glutamyltransferase; Hepatocytes; Humans; Insulin Resistance; Liver; Liver Cirrhosis; Liver Function Tests; Male; Melatonin; Middle Aged; Oxidative Stress; Phosphatidylcholines; Triglycerides; Tryptophan; Young Adult

2010
Changes in phosphatidylcholine fatty acid composition are associated with altered skeletal muscle insulin responsiveness in normal man.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:2

    Topics: Adult; Blood Glucose; Carbohydrate Metabolism; Cell Membrane; Fatty Acids; Female; Glucose Clamp Technique; Glycerol; Humans; Insulin; Insulin Resistance; Lipid Metabolism; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Niacin; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylethanolamines

2000

Other Studies

41 other study(ies) available for phosphatidylcholines and Insulin Sensitivity

ArticleYear
Lipidomic Approaches to Study HDL Metabolism in Patients with Central Obesity Diagnosed with Metabolic Syndrome.
    International journal of molecular sciences, 2022, Jun-17, Volume: 23, Issue:12

    Topics: Cholesterol; Cholesterol, HDL; Humans; Insulin Resistance; Lipidomics; Lipoproteins; Metabolic Syndrome; Obesity; Obesity, Abdominal; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines

2022
Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity.
    eLife, 2019, 08-16, Volume: 8

    Topics: Adipose Tissue; Animals; Choline-Phosphate Cytidylyltransferase; Disease Models, Animal; Gene Deletion; Humans; Inflammation; Insulin Resistance; Macrophages; Mice, Obese; Obesity; Phosphatidylcholines

2019
Green Tea Extract Treatment in Obese Mice with Nonalcoholic Steatohepatitis Restores the Hepatic Metabolome in Association with Limiting Endotoxemia-TLR4-NFκB-Mediated Inflammation.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:24

    Topics: Animals; Bile Acids and Salts; Catechin; Diet, High-Fat; Endotoxemia; Inflammation; Insulin Resistance; Liver; Male; Metabolome; Mice, Inbred C57BL; Mice, Obese; NF-kappa B; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Plant Extracts; Tea; Toll-Like Receptor 4

2019
Metabolomics profiles associated with HbA1c levels in patients with type 2 diabetes.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Aged; Amino Acids; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose; Glycated Hemoglobin; Glycine; Hexoses; Humans; Insulin Resistance; Male; Metabolomics; Middle Aged; Phosphatidylcholines; Valine

2019
The exogenous natural phospholipids, EPA-PC and EPA-PE, contribute to ameliorate inflammation and promote macrophage polarization.
    Food & function, 2020, Jul-01, Volume: 11, Issue:7

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Coculture Techniques; Cytokines; Diet; Eicosapentaenoic Acid; Inflammation; Insulin Resistance; Macrophage Activation; Macrophages; Male; Mice; Mice, Inbred C57BL; Obesity; Phosphatidylcholines; Phosphatidylethanolamines; RAW 264.7 Cells; Sea Cucumbers

2020
1,2-Dilinoleoyl-sn-glycero-3-phosphocholine increases insulin sensitivity in palmitate-treated myotubes and induces lipolysis in adipocytes.
    Biochemical and biophysical research communications, 2020, 11-26, Volume: 533, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Apoptosis; Cell Line; Inflammation; Insulin Resistance; Lipolysis; Mice; Muscle Fibers, Skeletal; Palmitates; Phosphatidylcholines; Tumor Necrosis Factor-alpha

2020
Exogenous natural EPA-enriched phosphatidylcholine and phosphatidylethanolamine ameliorate lipid accumulation and insulin resistance
    Food & function, 2020, Sep-23, Volume: 11, Issue:9

    Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Eicosapentaenoic Acid; Humans; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Phosphatidylcholines; PPAR alpha; PPAR gamma; Sea Cucumbers

2020
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes.
    Diabetologia, 2021, Volume: 64, Issue:2

    Topics: Adult; Autonomic Nervous System Diseases; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dyslipidemias; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heart Rate; Humans; Insulin Resistance; Lipid Metabolism; Lipidomics; Lysophosphatidylcholines; Male; Middle Aged; Obesity; Phosphatidylcholines; Sphingomyelins; Young Adult

2021
Genetic regulation of liver lipids in a mouse model of insulin resistance and hepatic steatosis.
    Molecular systems biology, 2021, Volume: 17, Issue:1

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Fatty Liver; Gene Expression Profiling; Gene Expression Regulation; Genetic Variation; Glucose; Insulin Resistance; Lipidomics; Male; MAP Kinase Kinase 6; Mice; Nuclear Proteins; Phosphatidylcholines; Triglycerides

2021
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance.
    Nature communications, 2021, 01-11, Volume: 12, Issue:1

    Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Dyslipidemias; Epithelial Cells; Exosomes; Fatty Liver; Feces; Gene Expression Regulation; Glucose Intolerance; Green Fluorescent Proteins; Humans; Insulin; Insulin Resistance; Interleukin-6; Intestines; Lipids; Liver; Macrophage Activation; Mice, Inbred C57BL; Phosphatidylcholines; Receptors, Aryl Hydrocarbon; Signal Transduction; Tetraspanin 30; Tumor Necrosis Factor-alpha; Up-Regulation

2021
Effect of different phosphatidylcholines on high fat diet-induced insulin resistance in mice.
    Food & function, 2021, Mar-01, Volume: 12, Issue:4

    Topics: Animals; Blood Glucose; Decapodiformes; Diet, High-Fat; Docosahexaenoic Acids; Eicosapentaenoic Acid; Gastrointestinal Microbiome; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Phosphatidylcholines

2021
Muscle Sympathetic Nerve Activity Is Associated With Elements of the Plasma Lipidomic Profile in Young Asian Adults.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: Asian; Blood Glucose; Ceramides; Cholesterol Esters; Cholesterol, HDL; Cholesterol, LDL; Diglycerides; Female; Gangliosides; Humans; Insulin Resistance; Lipid Metabolism; Lysophospholipids; Male; Muscle, Skeletal; Phosphatidylcholines; Phosphatidylethanolamines; Spectrometry, Mass, Electrospray Ionization; Sympathetic Nervous System; Triglycerides; White People; Young Adult

2017
Fatty Acid Composition of Plasma Phosphatidylcholine Determines Body Fat Parameters in Subjects with Metabolic Syndrome-Related Traits.
    Metabolic syndrome and related disorders, 2017, Volume: 15, Issue:7

    Topics: Adiposity; Adult; Anthropometry; Case-Control Studies; Chromatography, Liquid; Cross-Sectional Studies; Fatty Acids; Female; Humans; Insulin Resistance; Linear Models; Lipids; Male; Metabolic Syndrome; Middle Aged; Multivariate Analysis; Phosphatidylcholines; Pilot Projects; Regression Analysis; Stearoyl-CoA Desaturase; Waist Circumference; Waist-Hip Ratio

2017
From masochistic enzymology to mechanistic physiology and disease.
    The Journal of biological chemistry, 2017, 10-20, Volume: 292, Issue:42

    Topics: Animals; Atherosclerosis; Choline-Phosphate Cytidylyltransferase; Diet; Embryo, Mammalian; Gene Targeting; History, 20th Century; History, 21st Century; Humans; Insulin Resistance; Mice; Mice, Knockout; Obesity; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase

2017
Skeletal muscle phosphatidylcholine and phosphatidylethanolamine respond to exercise and influence insulin sensitivity in men.
    Scientific reports, 2018, 04-25, Volume: 8, Issue:1

    Topics: Exercise; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Lipid Droplets; Male; Mitochondria; Muscle, Skeletal; Oxidative Phosphorylation; Oxygen; Oxygen Consumption; Phosphatidylcholines; Phosphatidylethanolamines; TOR Serine-Threonine Kinases

2018
Altered Plasma Amino Acids and Lipids Associated With Abnormal Glucose Metabolism and Insulin Resistance in Older Adults.
    The Journal of clinical endocrinology and metabolism, 2018, 09-01, Volume: 103, Issue:9

    Topics: Aged; Aged, 80 and over; Amino Acids; Biomarkers; Blood Glucose; Fasting; Female; Glucose Tolerance Test; Glutamic Acid; Glycine; Humans; Insulin Resistance; Lipids; Longitudinal Studies; Lysophosphatidylcholines; Male; Metabolomics; Middle Aged; Odds Ratio; Phosphatidylcholines; Sphingomyelins

2018
Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in mice.
    Carbohydrate polymers, 2018, Nov-15, Volume: 200

    Topics: Animals; Basidiomycota; Diet, High-Fat; Fructose; Fungal Polysaccharides; Hypoglycemic Agents; Insulin Resistance; Intestinal Mucosa; Intestines; Liver; Male; Mice; Mice, Inbred C57BL; Microbiota; Obesity; Phosphatidylcholines; S-Adenosylmethionine; Sucrose; Vitamin B 12

2018
Metabolomic profile of insulin resistance in patients with multiple sclerosis is associated to the severity of the disease.
    Multiple sclerosis and related disorders, 2018, Volume: 25

    Topics: Adult; Aged; Blood Glucose; Body Mass Index; Butyrates; Disability Evaluation; Fasting; Female; Humans; Hydroxybutyrates; Insulin; Insulin Resistance; Male; Metabolomics; Middle Aged; Multiple Sclerosis; Phosphatidylcholines; Regression Analysis; Young Adult

2018
Modulation of Insulin Resistance and the Adipocyte-Skeletal Muscle Cell Cross-Talk by LCn-3PUFA.
    International journal of molecular sciences, 2018, Sep-15, Volume: 19, Issue:9

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Communication; Culture Media, Conditioned; Fatty Acids; Gene Expression; Insulin; Insulin Resistance; Membrane Lipids; Mice; Muscle Fibers, Skeletal; Phosphatidylcholines; Phosphorylation; Proto-Oncogene Proteins c-akt

2018
Short-term low-calorie diet remodels skeletal muscle lipid profile and metabolic gene expression in obese adults.
    American journal of physiology. Endocrinology and metabolism, 2019, 02-01, Volume: 316, Issue:2

    Topics: Adult; Caloric Restriction; Carboxy-Lyases; Cholesterol, HDL; Cholesterol, LDL; DNA-Binding Proteins; Fatty Acid Transport Proteins; Female; Gene Expression; Humans; Insulin; Insulin Resistance; Male; Mitochondrial Proteins; Muscle, Skeletal; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phosphatidylcholines; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Quadriceps Muscle; RNA, Messenger; Stearoyl-CoA Desaturase; Time Factors; Transcription Factors; Triglycerides

2019
A role for phosphatidylcholine and phosphatidylethanolamine in hepatic insulin signaling.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:4

    Topics: Animals; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Signal Transduction

2019
The efficacy of saxagliptin in T2DM patients with non-alcoholic fatty liver disease: preliminary data.
    Revista da Associacao Medica Brasileira (1992), 2019, Volume: 65, Issue:1

    Topics: Adamantane; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptides; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sulfonylurea Compounds; Treatment Outcome

2019
"Prediction is very hard, especially about the future": new biomarkers for type 2 diabetes?
    Diabetes, 2013, Volume: 62, Issue:5

    Topics: Animals; Diabetes Mellitus, Type 2; Female; Glucose Metabolism Disorders; Humans; Hydroxybutyrates; Insulin Resistance; Male; Phosphatidylcholines

2013
Lack of phosphatidylethanolamine N-methyltransferase in mice does not promote fatty acid oxidation in skeletal muscle.
    Biochimica et biophysica acta, 2016, Volume: 1861, Issue:2

    Topics: Animals; Diet, High-Fat; Dietary Fats; Energy Metabolism; Fatty Acids; Gene Expression; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Muscle Cells; Muscle, Skeletal; Obesity; Oxidation-Reduction; Oxygen Consumption; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Primary Cell Culture

2016
iPLA2β deficiency attenuates obesity and hepatic steatosis in ob/ob mice through hepatic fatty-acyl phospholipid remodeling.
    Biochimica et biophysica acta, 2016, Volume: 1861, Issue:5

    Topics: Animals; Apoptosis; Arachidonic Acid; Blood Glucose; Cholesterol Esters; Disease Models, Animal; Docosahexaenoic Acids; Fatty Acids; Gene Expression Regulation; Genotype; Group VI Phospholipases A2; Insulin; Insulin Resistance; Liver; Lysophospholipids; Male; Mice, Inbred C57BL; Mice, Knockout; Non-alcoholic Fatty Liver Disease; Obesity; Oxidation-Reduction; Phenotype; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; PPAR gamma; Triglycerides

2016
Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Jun-01, Volume: 120, Issue:11

    Topics: Adult; Athletes; Blood Glucose; Diabetes Mellitus, Type 2; Exercise; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxygen Consumption; Phosphatidylcholines; Phosphatidylethanolamines

2016
Biochanin A improves hepatic steatosis and insulin resistance by regulating the hepatic lipid and glucose metabolic pathways in diet-induced obese mice.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:9

    Topics: Animals; Diet, High-Fat; Genistein; Glucose; HEK293 Cells; Humans; Insulin Resistance; Lipid Metabolism; Liver; Male; Mice, Inbred C57BL; Mice, Obese; Non-alcoholic Fatty Liver Disease; Obesity; Phosphatidylcholines; PPAR alpha

2016
Alterations of the Lipid Metabolome in Dairy Cows Experiencing Excessive Lipolysis Early Postpartum.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Adipose Tissue; Animals; Cattle; Chromatography, Liquid; Dairying; Energy Metabolism; Fatty Acids, Nonesterified; Female; Insulin Resistance; Lactation; Lipids; Lipolysis; Lysophosphatidylcholines; Metabolome; Metabolomics; Milk; Parity; Phosphatidylcholines; Postpartum Period; Sphingomyelins; Tandem Mass Spectrometry

2016
Impaired de novo choline synthesis explains why phosphatidylethanolamine N-methyltransferase-deficient mice are protected from diet-induced obesity.
    The Journal of biological chemistry, 2010, Jul-16, Volume: 285, Issue:29

    Topics: Animals; Betaine; Choline; Diet; Dietary Fats; Dietary Supplements; Energy Metabolism; Fatty Liver; Feeding Behavior; Insulin Resistance; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; Phenotype; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Weight Gain

2010
Inverse association between serum phospholipid oleic acid and insulin resistance in subjects with primary dyslipidaemia.
    Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:5

    Topics: Adult; Biomarkers; Body Mass Index; Cross-Sectional Studies; Diet, Mediterranean; Dyslipidemias; Female; Fruit; Glucose Clamp Technique; Humans; Insulin Resistance; Linoleic Acid; Male; Middle Aged; Olea; Oleic Acid; Olive Oil; Phosphatidylcholines; Phospholipids; Plant Oils; Spain

2011
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects.
    Nature, 2011, May-25, Volume: 474, Issue:7352

    Topics: Animals; Bile Acids and Salts; Blood Glucose; Cell Line; Disease Models, Animal; Fatty Liver; HeLa Cells; Homeostasis; Humans; Hypoglycemic Agents; Insulin Resistance; Ligands; Lipogenesis; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Protein Binding; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Triglycerides

2011
Metabolism: A lipid for fat disorders.
    Nature, 2011, Jun-22, Volume: 474, Issue:7352

    Topics: 1,2-Dipalmitoylphosphatidylcholine; Animals; Bile Acids and Salts; Fatty Liver; Humans; Insulin Resistance; Liver; Mice; Phosphatidylcholines; Receptors, Cytoplasmic and Nuclear; Signal Transduction

2011
Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach.
    Diabetes, 2013, Volume: 62, Issue:2

    Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Glycine; Hexoses; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Metabolomics; Middle Aged; Phenylalanine; Phosphatidylcholines; Risk; Serum; Sphingomyelins

2013
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance.
    Diabetes, 2013, Volume: 62, Issue:5

    Topics: Adult; Animals; Biomarkers; Cell Line; Cohort Studies; Diabetes Mellitus, Type 2; Early Diagnosis; Female; Follow-Up Studies; Glucose Metabolism Disorders; Humans; Hydroxybutyrates; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Phosphatidylcholines; Prospective Studies; Rats; ROC Curve

2013
Plasma fatty acid profile in depressive disorder resembles insulin resistance state.
    Neuro endocrinology letters, 2012, Volume: 33 Suppl 2

    Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol Esters; Depressive Disorder; Diabetes Mellitus, Type 2; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Female; Humans; Insulin Resistance; Linoleoyl-CoA Desaturase; Male; Middle Aged; Oxidative Stress; Phosphatidylcholines; Risk Factors; Stearoyl-CoA Desaturase

2012
Fetal erythrocyte membrane lipids modification: preliminary observation of an early sign of compromised insulin sensitivity in offspring of gestational diabetic women.
    Diabetic medicine : a journal of the British Diabetic Association, 2005, Volume: 22, Issue:7

    Topics: Adult; Arachidonic Acid; Diabetes, Gestational; Docosahexaenoic Acids; Erythrocyte Membrane; Fatty Acids, Unsaturated; Female; Fetal Blood; Humans; Infant, Newborn; Insulin Resistance; Male; Maternal-Fetal Exchange; Phosphatidylcholines; Pregnancy; Triglycerides

2005
Homocysteine metabolism in ZDF (type 2) diabetic rats.
    Diabetes, 2005, Volume: 54, Issue:11

    Topics: Animals; Betaine; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hepatocytes; Homocysteine; Insulin Resistance; Liver; Methionine; Phosphatidylcholines; Rats; Rats, Zucker; RNA, Messenger

2005
gamma-tocopherol, but not alpha-tocopherol, potently inhibits neointimal formation induced by vascular injury in insulin resistant rats.
    Journal of molecular and cellular cardiology, 2006, Volume: 41, Issue:3

    Topics: Acridines; alpha-Tocopherol; Animals; Antioxidants; Blood Pressure; gamma-Tocopherol; Insulin; Insulin Resistance; Male; Muscle, Smooth, Vascular; Oxidative Stress; Phosphatidylcholines; Rats; Rats, Sprague-Dawley; Tunica Intima; Tyrosine; Vascular Diseases; Vitamin E

2006
Fasting and postprandial determinants for the occurrence of small dense LDL species in non-insulin-dependent diabetic patients with and without hypertriglyceridaemia: the involvement of insulin, insulin precursor species and insulin resistance.
    Atherosclerosis, 1995, Volume: 113, Issue:2

    Topics: Case-Control Studies; Centrifugation, Density Gradient; Diabetes Mellitus, Type 2; Eating; Fasting; Humans; Hypertriglyceridemia; Insulin; Insulin Resistance; Lipase; Lipoproteins, LDL; Male; Middle Aged; Multivariate Analysis; Phosphatidylcholines; Proinsulin; Radioimmunoassay

1995
Analyses of insulin-potentiating fragments of human growth hormone by computative simulation; essential unit for insulin-involved biological responses.
    Bioorganic & medicinal chemistry, 2000, Volume: 8, Issue:7

    Topics: Adipocytes; Adipose Tissue; Animals; Computer Simulation; Dose-Response Relationship, Drug; Electrophoresis, Agar Gel; Fatty Acids; Growth Hormone; Hexokinase; Humans; Insulin; Insulin Resistance; Isoenzymes; Isoproterenol; Lipolysis; Male; Micelles; Models, Molecular; Monosaccharide Transport Proteins; Peptide Fragments; Phosphatidylcholines; Protein Conformation; Rats; Rats, Wistar; RNA, Messenger; Thermodynamics

2000
Adipocyte and erythrocyte plasma membrane phospholipid composition and hyperinsulinemia: a study in nondiabetic and diabetic obese women.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2000, Volume: 24, Issue:12

    Topics: Adipocytes; Adult; Body Mass Index; Cell Membrane; Chromatography, High Pressure Liquid; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Fasting; Female; Homeostasis; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Middle Aged; Obesity; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Regression Analysis; Sphingomyelins

2000