phosphatidylcholines has been researched along with Diabetes Mellitus, Type 2 in 66 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (3.03) | 18.7374 |
| 1990's | 8 (12.12) | 18.2507 |
| 2000's | 16 (24.24) | 29.6817 |
| 2010's | 23 (34.85) | 24.3611 |
| 2020's | 17 (25.76) | 2.80 |
| Authors | Studies |
|---|---|
| Afshinnia, F; Byun, J; Callaghan, BC; Feldman, EL; Looker, HC; Michailidis, G; Nelson, RG; Pennathur, S; Rajendiran, TM; Reynolds, EL; Savelieff, MG; Soni, T | 1 |
| Cao, Y; Huang, L; Jin, E; Li, S; Qu, J; Ren, C; Tang, J; Wang, J; Wang, Z; Zhang, L; Zhao, M; Zhong, Y; Zhou, W | 1 |
| Bi, Y; Hou, T; Li, M; Lin, H; Lu, J; Ning, G; Wang, S; Wang, T; Wang, W; Xu, M; Xu, Y; Zhao, Z; Zheng, J | 1 |
| Cai, Z; Cheung, CKY; Cheung, CYY; Fong, CHY; Lam, KSL; Lee, CH; Liu, Y; Ru, Y; Su, X; Xu, A; Zhong, J | 1 |
| Chan, CB; Moftah, S; Yuzbashian, E | 1 |
| Bartell, TR; Buckley, JP; Hong, X; Pearson, C; Wang, G; Wang, X | 1 |
| Allin, KH; Carlsson, ER; Fenger, M; Madsbad, S | 1 |
| Choi, HJ; Jeon, HJ; Kim, BJ; Kim, JM; Kim, YJ; Lee, HS; Oh, T; Yu, HY; Yun, JH | 1 |
| Maev, IV; Palgova, LK; Pavlov, CS; Samsonov, AA; Shirokova, EN; Starostin, KM; Vovk, EI | 2 |
| Tuomainen, TP; Virtanen, JK; Voutilainen, S | 1 |
| Bao, X; Qian, K; Yao, P | 1 |
| Li, Z; Liu, Y; Tian, Y; Wang, J; Wang, Y; Xu, J; Xue, C | 1 |
| Bönhof, GJ; Knebel, B; Kotzka, J; Roden, M; Straßburger, K; Strom, A; Szendroedi, J; Ziegler, D | 1 |
| Bairaktari, ET; Elisaf, M; Ferrannini, E; Kostara, CE; Papathanasiou, A; Tsimihodimos, V | 1 |
| Bohler, HCL; Dryden, GW; Han, X; Kumar, A; Lei, C; McClain, CJ; Merchant, ML; Mu, J; Park, JW; Qin, C; Qiu, X; Sriwastva, MK; Sundaram, K; Teng, Y; Wang, B; Xu, F; Xu, Z; Yan, J; Zhang, HG; Zhang, L; Zhang, S; Zhang, X | 1 |
| Cao, M; Deng, M; Feng, K; Lam, SM; Li, B; Ping, F; Shui, G; Song, G; Wang, T; Wang, X; Wang, Z; Xiao, X; Xu, J; Yu, M; Zhai, X; Zhang, H; Zhang, Q; Zhou, L | 1 |
| Brandtner, EM; Dopheide, JF; Drexel, H; Fraunberger, P; Jylhä, A; Kleber, M; Laaksonen, R; Lääperi, M; Leiherer, A; Mader, A; März, W; Mündlein, A; Ramadani, H; Säly, CH; Vonbank, A | 1 |
| Abcouwer, SF; Afshinnia, F; Byun, J; Fort, PE; Gardner, TW; Kretzler, M; Looker, HC; Michailidis, G; Nelson, RG; Pennathur, S; Rajendiran, TM; Roger, JE; Shan, Y; Soni, T | 1 |
| Dempsey, PC; Dunstan, DW; Grace, MS; Kingwell, BA; Meikle, PJ; Mellett, NA; Mundra, PA; Owen, N; Sethi, P; Weir, JM | 1 |
| Furey, A; Likhodii, S; Liu, M; Randell, EW; Sun, G; Zhai, G; Zhang, W | 1 |
| Auriola, S; Bergdahl, IA; Brunius, C; Hanhineva, K; Landberg, R; Lehtonen, M; Rolandsson, O; Shi, L | 1 |
| Becher, S; Esch, P; Heiles, S | 1 |
| Barbas, C; Ciborowski, M; Gil de la Fuente, A; Godzien, J; Kretowski, A; Otero, A; Siroka, J; Traldi, F | 1 |
| Hu, C; Jia, W; Jiang, F; Wang, J; Wang, S; Yan, D; Zhang, R; Zhao, A; Zheng, X | 1 |
| Fan, B; Guo, XL; Li, JJ; Zhang, P; Zheng, ZS | 1 |
| Miyazawa, T; Nakagawa, K; Suzuki, K | 1 |
| Bain, JR; Lowe, WL | 1 |
| Adamski, J; Boeing, H; Drogan, D; Floegel, A; Pischon, T; Prehn, C; Schulze, MB; von Ruesten, A | 1 |
| Adamski, J; Claussnitzer, M; Grallert, H; Hauner, H; Heier, M; Heukamp, I; Huth, C; Illig, T; Kastenmüller, G; Kirchhofer, A; Krug, S; Laumen, H; Lechner, A; Meisinger, C; Peters, A; Prehn, C; Römisch-Margl, W; Seissler, J; Then, C; Thorand, B; Wahl, S | 1 |
| Acar, N; Berdeaux, O; Bretillon, L; Bron, AM; Cabaret, S; Creuzot-Garcher, CP; Grégoire, S; Isaïco, R; Koehrer, P; Saab, S | 1 |
| He, J; Howard, BV; Hyun, N; Jones, D; Lee, ET; Tran, VT; Uppal, K; Yu, T; Zeng, D; Zhao, J; Zhu, Y | 1 |
| Chiuve, SE; Hu, FB; Li, Y; Manson, JE; Qi, L; Wang, DD; Willett, WC | 1 |
| Bacon, SD; Bergman, BC; Brozinick, JT; Bui, HH; D'Alessandro, A; Hansen, KC; Kerege, AA; Kiseljak-Vassiliades, K; Kuo, MS; Nemkov, T; Newsom, SA; Perreault, L; Sanders, P; Siddall, P; Strauss, AN; Thomas, M; Wei, T | 1 |
| Walker, AK | 1 |
| Dore, TM; Jesus, AR; Machuqueiro, M; Marques, AP; Rauter, AP; Vila-Viçosa, D | 1 |
| Bao, S; Barter, PJ; Bonnet, DJ; Brown, BE; Curtiss, LK; Davies, MJ; Dusting, GJ; Jenkins, AJ; Lambert, G; Nobécourt, E; Puranik, R; Rye, KA; Tabet, F; Yan, L | 1 |
| Adamski, J; Boeing, H; Drogan, D; Floegel, A; Fritsche, A; Häring, HU; Hrabě de Angelis, M; Illig, T; Joost, HG; Mühlenbruch, K; Peters, A; Pischon, T; Prehn, C; Roden, M; Schulze, MB; Stefan, N; Wang-Sattler, R; Yu, Z | 1 |
| Adam, KP; Adamski, J; Camastra, S; Ferrannini, E; Gall, WE; Groop, L; Kastenmüller, G; Lyssenko, V; Mari, A; Milburn, MV; Nannipieri, M; Natali, A; Tuomi, T | 1 |
| Jirak, R; Macasek, J; Tvrzicka, E; Vareka, T; Vecka, M; Zak, A; Zeman, M | 1 |
| Cassagne, C; Diakou, V; Gin, H; Maneta-Peyret, L; Perret, AM; Poix, J; Vergnot, V | 1 |
| Knight, JD; Miranker, AD | 1 |
| Leiter, EH; Pan, HJ; Reifsnyder, P; Vance, DE; Xiao, Q | 1 |
| Cai, H; Higuchi, O; Miyazawa, T; Mune, M; Nakagawa, K; Oak, JH; Oikawa, S; Otani, H; Tsuzuki, T | 1 |
| Brosnan, JT; Brosnan, ME; Hall, B; Ratnam, S; Wijekoon, EP; Zeisel, SH | 1 |
| Chen, YE; Leiter, EH; Lin, Y; Pan, HJ; Vance, DE | 1 |
| Arsić, A; Blazencić Mladenović, V; Postić, M; Ristić Medić, D; Ristić, G; Ristić, V; Tepsić, J | 1 |
| Mackness, B; Mackness, M; Mastorikou, M | 1 |
| Frohman, MA; Huang, P | 1 |
| Harada, AS; Lau, W | 1 |
| Attia, N; Chaaba, R; Chanussot, F; Hamda, KB; Hammami, M; Hammami, S; Moulin, P; Nakbi, A; Smaoui, M | 1 |
| Plehwe, WE; Shearman, RP; Storey, GN; Turtle, JR | 1 |
| Betteridge, DJ; Cooper, MB; Freeman, DJ; Griffin, BA; Hales, CN; Ling, KL; Packard, CJ; Shepherd, J; Tan, KC | 1 |
| Boisseau, MR; Claverie, M; Crockett, R; Freyburger, G; Gin, H; Lacape, G; Lardeau, D; Le Moigne, F; Seigneur, M | 1 |
| Heintz, B; Hesse, K; Kirsten, R; Nelson, K; Nemeth, N; Oremek, G; Schneider, E | 1 |
| Boku, A; Ochiai, S; Onuma, T; Takebe, K; Tamasawa, A; Tsutsui, M | 1 |
| Driscoll, D; Ennis, W; Meneses, P | 1 |
| Boisseau, MR; Cassagne, C; Freyburger, G; Gin, H; Labrouche, S | 1 |
| Avignon, A; Bandyopadhyay, G; Farese, RV; Standaert, ML; Yamada, K | 1 |
| Gromnatskiĭ, NI; Kirichenko, LL; Mel'chinskaia, EN | 1 |
| Donner, M; Drouin, P; Meyer, L; Younsi, M; Zeghari, N; Ziegler, O | 1 |
| Funakoshi, A; Hayashi, H; Ichikawa, M; Kanai, S; Miyasaka, K; Sato, Y | 1 |
| Hirayama, Y; Ishigaki, Y; Miyazawa, T; Nagashima, T; Oikawa, S; Sekikawa, A; Tokita, Y; Yamada, R | 1 |
| Moore, TR | 1 |
| Curatola, G; Dousset, N; Ferretti, G; Solèra, ML; Taus, M; Valdiguie, P | 1 |
| Frohlich, J; Godin, DV | 1 |
5 review(s) available for phosphatidylcholines and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study.
Topics: Choline; Coronary Artery Disease; Diabetes Mellitus, Type 2; Genome-Wide Association Study; Glycine; Humans; Mendelian Randomization Analysis; Phosphatidylcholines; Polymorphism, Single Nucleotide; Risk Factors; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
Graduate Student Literature Review: A scoping review on the impact of consumption of dairy products on phosphatidylcholine and lysophosphatidylcholine in circulation and the liver in human studies and animal models.
Topics: Animals; Dairy Products; Diabetes Mellitus, Type 2; Diet; Humans; Liver; Lysophosphatidylcholines; Milk; Models, Animal; Phosphatidylcholines; Students; Yogurt | 2023 |
Augmentation of blood lipid glycation and lipid oxidation in diabetic patients.
Topics: Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Erythrocytes; Glycation End Products, Advanced; Glycolipids; Glycosylation; Humans; Lipid Peroxidation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Tandem Mass Spectrometry | 2014 |
1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver.
Topics: Animals; Carbon Cycle; Diabetes Mellitus, Type 2; Fatty Liver; Humans; Lipogenesis; Phosphatidylcholines; S-Adenosylmethionine | 2017 |
The potential for phospholipase D as a new therapeutic target.
Topics: Animals; Apoptosis; Cell Line, Tumor; Diabetes Mellitus, Type 2; Drug Delivery Systems; Endocytosis; Enzyme Inhibitors; Exocytosis; Gene Expression Regulation, Enzymologic; Humans; Mammals; Membrane Lipids; Neoplasm Proteins; Neoplasms; Organ Specificity; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Isoforms; Protein Structure, Tertiary; Subcellular Fractions | 2007 |
3 trial(s) available for phosphatidylcholines and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Breaking Up Prolonged Sitting Alters the Postprandial Plasma Lipidomic Profile of Adults With Type 2 Diabetes.
Topics: Aged; Cross-Over Studies; Diabetes Mellitus, Type 2; Diglycerides; Exercise; Female; Humans; Inflammation; Linear Models; Lipid Metabolism; Male; Mass Spectrometry; Middle Aged; Obesity; Overweight; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Plasmalogens; Postprandial Period; Posture; Sedentary Behavior; Triglycerides | 2017 |
Novel metabolic markers for the risk of diabetes development in American Indians.
Topics: Adult; Biomarkers; Biphenyl Compounds; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Indians, North American; Insulin Resistance; Isoflavones; Logistic Models; Male; Metabolomics; Oligopeptides; Phosphatidylcholines; Prospective Studies; Risk Factors | 2015 |
Polyenylphosphatidylcholine improves the lipoprotein profile in diabetic patients.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hyperlipidemias; Male; Middle Aged; Phosphatidylcholines; Triglycerides | 1994 |
58 other study(ies) available for phosphatidylcholines and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Fatty Acids, Nonesterified; Female; Humans; Lipidomics; Lysophosphatidylcholines; Male; Middle Aged; Phosphatidylcholines; Retrospective Studies | 2022 |
Metabolomic comparison followed by cross-validation of enzyme-linked immunosorbent assay to reveal potential biomarkers of diabetic retinopathy in Chinese with type 2 diabetes.
Topics: Aged; Biomarkers; Carnitine; Case-Control Studies; Chenodeoxycholic Acid; China; Citrulline; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Eicosapentaenoic Acid; Enzyme-Linked Immunosorbent Assay; Humans; Metabolomics; Phosphatidylcholines | 2022 |
Specific triacylglycerol, diacylglycerol, and lyso-phosphatidylcholine species for the prediction of type 2 diabetes: a ~ 16-year prospective study in Chinese.
Topics: Animals; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diglycerides; Mice; Models, Statistical; Phosphatidylcholines; Prediabetic State; Prognosis; Prospective Studies; Triglycerides | 2022 |
Gestational Diabetes Mellitus, Postpartum Lipidomic Signatures, and Subsequent Risk of Type 2 Diabetes: A Lipidome-Wide Association Study.
Topics: Adult; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Infant; Lipidomics; Male; Phosphatidylcholines; Postpartum Period; Pregnancy; Prospective Studies | 2023 |
Phosphatidylcholine and its relation to apolipoproteins A-1 and B changes after Roux-en-Y gastric bypass: a cohort study.
Topics: Adult; Apolipoprotein A-I; Apolipoprotein B-100; Cholesterol, LDL; Cholesterol, VLDL; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Lipid Metabolism; Male; Middle Aged; Obesity, Morbid; Phosphatidylcholines; Weight Loss | 2019 |
Metabolomics profiles associated with HbA1c levels in patients with type 2 diabetes.
Topics: Aged; Amino Acids; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose; Glycated Hemoglobin; Glycine; Hexoses; Humans; Insulin Resistance; Male; Metabolomics; Middle Aged; Phosphatidylcholines; Valine | 2019 |
Effectiveness of phosphatidylcholine in alleviating steatosis in patients with non-alcoholic fatty liver disease and cardiometabolic comorbidities (MANPOWER study).
Topics: Adult; Comorbidity; Diabetes Mellitus, Type 2; Humans; Hypertension; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Prevalence; Prospective Studies; Workforce | 2020 |
Dietary intake of choline and phosphatidylcholine and risk of type 2 diabetes in men: The Kuopio Ischaemic Heart Disease Risk Factor Study.
Topics: Choline; Diabetes Mellitus, Type 2; Diet; Eating; Finland; Heart Disease Risk Factors; Humans; Male; Phosphatidylcholines; Prospective Studies; Risk Factors | 2020 |
Effectiveness of phosphatidylcholine as adjunctive therapy in improving liver function tests in patients with non-alcoholic fatty liver disease and metabolic comorbidities: real-life observational study from Russia.
Topics: Adult; Comorbidity; Diabetes Mellitus, Type 2; Humans; Liver Function Tests; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Russia | 2020 |
Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice.
Topics: Administration, Oral; Animals; Blood Glucose; Cholic Acid; Diabetes Mellitus, Type 2; Drug Carriers; Exenatide; Gastrointestinal Tract; Glycated Hemoglobin; Half-Life; Hypoglycemic Agents; Insulin-Secreting Cells; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Nanoparticles; Permeability; Phosphatidylcholines; Zein | 2020 |
Exogenous natural EPA-enriched phosphatidylcholine and phosphatidylethanolamine ameliorate lipid accumulation and insulin resistance
Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Eicosapentaenoic Acid; Humans; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Phosphatidylcholines; PPAR alpha; PPAR gamma; Sea Cucumbers | 2020 |
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes.
Topics: Adult; Autonomic Nervous System Diseases; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dyslipidemias; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heart Rate; Humans; Insulin Resistance; Lipid Metabolism; Lipidomics; Lysophosphatidylcholines; Male; Middle Aged; Obesity; Phosphatidylcholines; Sphingomyelins; Young Adult | 2021 |
Early Signs of Atherogenic Features in the HDL Lipidomes of Normolipidemic Patients Newly Diagnosed with Type 2 Diabetes.
Topics: Aged; Atherosclerosis; Cholesterol, HDL; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Lipidomics; Lipoproteins, HDL; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Sphingomyelins; Triglycerides | 2020 |
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance.
Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Dyslipidemias; Epithelial Cells; Exosomes; Fatty Liver; Feces; Gene Expression Regulation; Glucose Intolerance; Green Fluorescent Proteins; Humans; Insulin; Insulin Resistance; Interleukin-6; Intestines; Lipids; Liver; Macrophage Activation; Mice, Inbred C57BL; Phosphatidylcholines; Receptors, Aryl Hydrocarbon; Signal Transduction; Tetraspanin 30; Tumor Necrosis Factor-alpha; Up-Regulation | 2021 |
Localized increases in CEPT1 and ATGL elevate plasmalogen phosphatidylcholines in HDLs contributing to atheroprotective lipid profiles in hyperglycemic GCK-MODY.
Topics: Diabetes Mellitus, Type 2; Glucokinase; Humans; Mutation; Phosphatidylcholines; Plasmalogens | 2021 |
Lipid profiles of patients with manifest coronary versus peripheral atherosclerosis - Is there a difference?
Topics: Atherosclerosis; Ceramides; Coronary Artery Disease; Diabetes Mellitus, Type 2; Humans; Lipids; Lipoproteins; Peripheral Arterial Disease; Phosphatidylcholines; Risk Factors | 2021 |
Diminished retinal complex lipid synthesis and impaired fatty acid β-oxidation associated with human diabetic retinopathy.
Topics: Adult; Aged; American Indian or Alaska Native; Arizona; Black or African American; Carnitine; Case-Control Studies; Ceramides; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diglycerides; Disease Progression; Esters; Female; Hispanic or Latino; Humans; Lipidomics; Male; Mass Spectrometry; Middle Aged; Mitochondria; Phosphatidylcholines; Retina; Triglycerides; White People | 2021 |
Hyperglycemia-related advanced glycation end-products is associated with the altered phosphatidylcholine metabolism in osteoarthritis patients with diabetes.
Topics: Aged; Biomarkers; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Osteoarthritis; Phosphatidylcholines; Synovial Fluid; Tandem Mass Spectrometry | 2017 |
Plasma metabolites associated with type 2 diabetes in a Swedish population: a case-control study nested in a prospective cohort.
Topics: Adult; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus, Type 2; Disease Progression; Female; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Phosphatidylcholines; Plasma; Prospective Studies; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Sweden | 2018 |
Relative Quantification of Phosphatidylcholine sn-Isomers Using Positive Doubly Charged Lipid-Metal Ion Complexes.
Topics: Animals; Chromatography, High Pressure Liquid; Coordination Complexes; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids; Female; Ions; Iron; Isomerism; Limit of Detection; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization; Ultraviolet Rays | 2018 |
Characterization and annotation of oxidized glycerophosphocholines for non-targeted metabolomics with LC-QTOF-MS data.
Topics: Chromatography, Liquid; Databases, Factual; Diabetes Mellitus, Type 2; Humans; Mass Spectrometry; Metabolomics; Molecular Structure; Oxidation-Reduction; Phosphatidylcholines | 2018 |
Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach.
Topics: Adult; Aged; Aspartic Acid; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glutamic Acid; Haptoglobins; Humans; Male; Metabolomics; Middle Aged; Phosphatidylcholines | 2019 |
The efficacy of saxagliptin in T2DM patients with non-alcoholic fatty liver disease: preliminary data.
Topics: Adamantane; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptides; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sulfonylurea Compounds; Treatment Outcome | 2019 |
"Prediction is very hard, especially about the future": new biomarkers for type 2 diabetes?
Topics: Animals; Diabetes Mellitus, Type 2; Female; Glucose Metabolism Disorders; Humans; Hydroxybutyrates; Insulin Resistance; Male; Phosphatidylcholines | 2013 |
Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam.
Topics: Adult; Amino Acids; Carnitine; Chronic Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet; Feeding Behavior; Female; Hexoses; Humans; Male; Metabolome; Metabolomics; Middle Aged; Phosphatidylcholines; Risk Factors; Surveys and Questionnaires | 2013 |
Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146.
Topics: Alleles; Blood Glucose; Diabetes Mellitus, Type 2; Genotype; Glucose Tolerance Test; Glycerophospholipids; Humans; Insulin; Male; Metabolome; Metabolomics; Middle Aged; Phosphatidylcholines; Polymorphism, Genetic; Sphingomyelins; Transcription Factor 7-Like 2 Protein | 2013 |
Erythrocyte phospholipid and polyunsaturated fatty acid composition in diabetic retinopathy.
Topics: Adult; Aged; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Erythrocyte Membrane; Fatty Acids, Unsaturated; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Plasmalogens; Severity of Illness Index | 2014 |
Dietary phosphatidylcholine intake and type 2 diabetes in men and women.
Topics: Diabetes Mellitus, Type 2; Diet; Feeding Behavior; Female; Humans; Male; Phosphatidylcholines; Risk Factors | 2015 |
Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans.
Topics: Adult; Athletes; Blood Glucose; Diabetes Mellitus, Type 2; Exercise; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxygen Consumption; Phosphatidylcholines; Phosphatidylethanolamines | 2016 |
Targeting Type 2 Diabetes with C-Glucosyl Dihydrochalcones as Selective Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Synthesis and Biological Evaluation.
Topics: Chalcones; Diabetes Mellitus, Type 2; Glucosides; HEK293 Cells; Humans; Membranes, Artificial; Molecular Docking Simulation; Phosphatidylcholines; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2017 |
Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I.
Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Apolipoprotein A-I; Carotid Arteries; Carotid Artery Injuries; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Glycosylation; Humans; I-kappa B Proteins; Inflammation; Infusions, Parenteral; Intercellular Adhesion Molecule-1; Lipoproteins, HDL; Neutrophil Infiltration; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylcholines; Phosphorylation; Protein Processing, Post-Translational; Pyruvaldehyde; Rabbits; Reactive Oxygen Species; Time Factors; Vascular Cell Adhesion Molecule-1 | 2010 |
Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach.
Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Glycine; Hexoses; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Metabolomics; Middle Aged; Phenylalanine; Phosphatidylcholines; Risk; Serum; Sphingomyelins | 2013 |
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance.
Topics: Adult; Animals; Biomarkers; Cell Line; Cohort Studies; Diabetes Mellitus, Type 2; Early Diagnosis; Female; Follow-Up Studies; Glucose Metabolism Disorders; Humans; Hydroxybutyrates; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Phosphatidylcholines; Prospective Studies; Rats; ROC Curve | 2013 |
Plasma fatty acid profile in depressive disorder resembles insulin resistance state.
Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol Esters; Depressive Disorder; Diabetes Mellitus, Type 2; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Female; Humans; Insulin Resistance; Linoleoyl-CoA Desaturase; Male; Middle Aged; Oxidative Stress; Phosphatidylcholines; Risk Factors; Stearoyl-CoA Desaturase | 2012 |
Anti-phospholipid antibodies in diabetes mellitus.
Topics: Adult; Antibodies, Antiphospholipid; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Phosphatidylcholines; Phosphatidylinositols; Reference Values | 2002 |
Phospholipid catalysis of diabetic amyloid assembly.
Topics: Amino Acid Sequence; Amyloid; Animals; Diabetes Mellitus, Type 2; Female; Humans; Islet Amyloid Polypeptide; Lipid Bilayers; Liposomes; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Sequence Alignment | 2004 |
Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Hypoglycemic Agents; Liver; Male; Mice; Mice, Congenic; Pharmacogenetics; Phenotype; Phosphatidylcholines; Rosiglitazone; Thiazolidinediones | 2005 |
Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes.
Topics: Adult; Aged; Chromatography, Liquid; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipids; Mass Spectrometry; Middle Aged; Models, Chemical; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Reactive Oxygen Species | 2005 |
Homocysteine metabolism in ZDF (type 2) diabetic rats.
Topics: Animals; Betaine; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hepatocytes; Homocysteine; Insulin Resistance; Liver; Methionine; Phosphatidylcholines; Rats; Rats, Zucker; RNA, Messenger | 2005 |
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism.
Topics: Animals; Cardiolipins; Cardiovascular System; Choline-Phosphate Cytidylyltransferase; Crosses, Genetic; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred NOD; Mice, Obese; Mitochondria, Heart; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; PPAR gamma; Rosiglitazone; Thiazolidinediones | 2006 |
Effects of soybean D-LeciVita product on serum lipids and fatty acid composition in type 2 diabetic patients with hyperlipidemia.
Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Dietary Supplements; Fatty Acids; Female; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Phosphatidylcholines; Soybean Proteins | 2006 |
Defective metabolism of oxidized phospholipid by HDL from people with type 2 diabetes.
Topics: Adult; Aryldialkylphosphatase; Coronary Disease; Diabetes Mellitus, Type 2; Gene Frequency; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Polymorphism, Genetic; Reference Values; Sequence Deletion | 2006 |
Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole.
Topics: Alcaligenes; Amphotericin B; Amputation, Surgical; Antifungal Agents; Cefazolin; Combined Modality Therapy; Debridement; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Drug Resistance, Multiple, Fungal; Escherichia coli Infections; Fatal Outcome; Fluconazole; Gangrene; Graft Rejection; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney Transplantation; Leg; Leg Ulcer; Male; Middle Aged; Mucor; Mucormycosis; Penicillanic Acid; Phosphatidylcholines; Phosphatidylglycerols; Piperacillin; Postoperative Complications; Pyrimidines; Renal Dialysis; Reoperation; Sepsis; Skin Transplantation; Tazobactam; Triazoles; Voriconazole | 2007 |
Increased phospholipid transfer protein activity associated with the impaired cellular cholesterol efflux in type 2 diabetic subjects with coronary artery disease.
Topics: Adult; Animals; Apolipoprotein A-I; Apolipoproteins B; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; Cholesterol, HDL; Cholesterol, VLDL; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Liposomes; Liver Neoplasms, Experimental; Male; Middle Aged; Phosphatidylcholines; Phospholipid Transfer Proteins; Rats; Triglycerides | 2007 |
Outcome of pregnancy complicated by diabetes: experience with 232 patients in a 4 year period.
Topics: Abnormalities, Multiple; Amniotic Fluid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fetal Blood; Gestational Age; Humans; Hydrogen-Ion Concentration; Hypocalcemia; Hypoglycemia; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Phosphatidylcholines; Pregnancy; Pregnancy in Diabetics; Respiratory Distress Syndrome, Newborn; Sphingomyelins | 1984 |
Fasting and postprandial determinants for the occurrence of small dense LDL species in non-insulin-dependent diabetic patients with and without hypertriglyceridaemia: the involvement of insulin, insulin precursor species and insulin resistance.
Topics: Case-Control Studies; Centrifugation, Density Gradient; Diabetes Mellitus, Type 2; Eating; Fasting; Humans; Hypertriglyceridemia; Insulin; Insulin Resistance; Lipase; Lipoproteins, LDL; Male; Middle Aged; Multivariate Analysis; Phosphatidylcholines; Proinsulin; Radioimmunoassay | 1995 |
Serum fatty acid profiles in type I and type II diabetes: metabolic alterations of fatty acids of the main serum lipids.
Topics: Adult; Aged; Cholesterol; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Sphingomyelins; Triglycerides | 1994 |
Lipid composition of platelets in patients with non-insulin-dependent diabetes mellitus: studies before and after treatment of diabetes.
Topics: Blood Platelets; Cholesterol; Diabetes Mellitus, Type 2; Humans; Insulin; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Reference Values; Sphingomyelins; Triglycerides | 1994 |
Human sciatic nerve phospholipid profiles from non-diabetes mellitus, non-insulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus individuals. A 31P NMR spectroscopy study.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Plasmalogens; Sciatic Nerve; Sphingomyelins | 1994 |
Changes in phospholipid composition of blood cell membranes (erythrocyte, platelet, and polymorphonuclear) in different types of diabetes--clinical and biological correlations.
Topics: Adult; Aged; Blood Platelets; Cell Membrane; Densitometry; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Female; Humans; Male; Middle Aged; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Sphingomyelins | 1996 |
The phosphatidylinositol 3-kinase inhibitor, wortmannin, inhibits insulin-induced activation of phosphatidylcholine hydrolysis and associated protein kinase C translocation in rat adipocytes.
Topics: Adipose Tissue; Androstadienes; Animals; Biological Transport, Active; Diabetes Mellitus, Type 2; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; In Vitro Techniques; Indoles; Insulin; Isoenzymes; Male; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rats; Wortmannin | 1996 |
[Hypolipidemic effects of alisat and lipostabil in patients with diabetes mellitus].
Topics: Adult; Aged; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Fat Emulsions, Intravenous; Female; Garlic; Humans; Hyperlipidemias; Male; Middle Aged; Phosphatidylcholines; Plants, Medicinal; Triglycerides | 2000 |
Adipocyte and erythrocyte plasma membrane phospholipid composition and hyperinsulinemia: a study in nondiabetic and diabetic obese women.
Topics: Adipocytes; Adult; Body Mass Index; Cell Membrane; Chromatography, High Pressure Liquid; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Fasting; Female; Homeostasis; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Middle Aged; Obesity; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Regression Analysis; Sphingomyelins | 2000 |
Increased lymphatic lipid transport in genetically diabetic obese rats.
Topics: Animals; Bile Acids and Salts; Body Weight; Carrier Proteins; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy Intake; Fistula; Hypoglycemic Agents; Lymphatic System; Male; Obesity; Phosphatidylcholines; Physical Conditioning, Animal; Rats; Rats, Inbred OLETF; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 2002 |
Increase of serum phosphatidylcholine hydroperoxide dependent on glycemic control in type 2 diabetic patients.
Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Lipoproteins, HDL; Male; Middle Aged; Phosphatidylcholines; Phospholipids; Reference Values; Triglycerides | 2002 |
A comparison of amniotic fluid fetal pulmonary phospholipids in normal and diabetic pregnancy.
Topics: Amniocentesis; Amniotic Fluid; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Fetal Organ Maturity; Gestational Age; Humans; Linear Models; Lung; Odds Ratio; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylinositols; Phospholipids; Pregnancy; Pregnancy in Diabetics; Racial Groups; Sphingomyelins | 2002 |
Lower susceptibility of low density lipoprotein to in vitro oxidation in diabetic patients.
Topics: Adult; Copper; Copper Sulfate; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diphenylhexatriene; Female; Fluorescence Polarization; Humans; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Phosphatidylcholines; Trinitrobenzenesulfonic Acid | 1992 |
Erythrocyte membrane alterations and plasma lipids in patients with chylomicronemia and in Tangier disease.
Topics: Adolescent; Adult; Apolipoprotein C-II; Apolipoproteins C; Ca(2+) Mg(2+)-ATPase; Chylomicrons; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Humans; Hypolipoproteinemias; Lipids; Lipoprotein Lipase; Male; Middle Aged; Phosphatidylcholines; Sodium-Potassium-Exchanging ATPase; Sphingomyelins; Tangier Disease | 1986 |