Compounds > phosphatidylcholines
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phosphatidylcholines and Diabetes Mellitus, Adult-Onset

phosphatidylcholines has been researched along with Diabetes Mellitus, Adult-Onset in 66 studies

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-19902 (3.03)18.7374
1990's8 (12.12)18.2507
2000's16 (24.24)29.6817
2010's23 (34.85)24.3611
2020's17 (25.76)2.80

Authors

AuthorsStudies
Afshinnia, F; Byun, J; Callaghan, BC; Feldman, EL; Looker, HC; Michailidis, G; Nelson, RG; Pennathur, S; Rajendiran, TM; Reynolds, EL; Savelieff, MG; Soni, T1
Cao, Y; Huang, L; Jin, E; Li, S; Qu, J; Ren, C; Tang, J; Wang, J; Wang, Z; Zhang, L; Zhao, M; Zhong, Y; Zhou, W1
Bi, Y; Hou, T; Li, M; Lin, H; Lu, J; Ning, G; Wang, S; Wang, T; Wang, W; Xu, M; Xu, Y; Zhao, Z; Zheng, J1
Cai, Z; Cheung, CKY; Cheung, CYY; Fong, CHY; Lam, KSL; Lee, CH; Liu, Y; Ru, Y; Su, X; Xu, A; Zhong, J1
Chan, CB; Moftah, S; Yuzbashian, E1
Bartell, TR; Buckley, JP; Hong, X; Pearson, C; Wang, G; Wang, X1
Allin, KH; Carlsson, ER; Fenger, M; Madsbad, S1
Choi, HJ; Jeon, HJ; Kim, BJ; Kim, JM; Kim, YJ; Lee, HS; Oh, T; Yu, HY; Yun, JH1
Maev, IV; Palgova, LK; Pavlov, CS; Samsonov, AA; Shirokova, EN; Starostin, KM; Vovk, EI2
Tuomainen, TP; Virtanen, JK; Voutilainen, S1
Bao, X; Qian, K; Yao, P1
Li, Z; Liu, Y; Tian, Y; Wang, J; Wang, Y; Xu, J; Xue, C1
Bönhof, GJ; Knebel, B; Kotzka, J; Roden, M; Straßburger, K; Strom, A; Szendroedi, J; Ziegler, D1
Bairaktari, ET; Elisaf, M; Ferrannini, E; Kostara, CE; Papathanasiou, A; Tsimihodimos, V1
Bohler, HCL; Dryden, GW; Han, X; Kumar, A; Lei, C; McClain, CJ; Merchant, ML; Mu, J; Park, JW; Qin, C; Qiu, X; Sriwastva, MK; Sundaram, K; Teng, Y; Wang, B; Xu, F; Xu, Z; Yan, J; Zhang, HG; Zhang, L; Zhang, S; Zhang, X1
Cao, M; Deng, M; Feng, K; Lam, SM; Li, B; Ping, F; Shui, G; Song, G; Wang, T; Wang, X; Wang, Z; Xiao, X; Xu, J; Yu, M; Zhai, X; Zhang, H; Zhang, Q; Zhou, L1
Brandtner, EM; Dopheide, JF; Drexel, H; Fraunberger, P; Jylhä, A; Kleber, M; Laaksonen, R; Lääperi, M; Leiherer, A; Mader, A; März, W; Mündlein, A; Ramadani, H; Säly, CH; Vonbank, A1
Abcouwer, SF; Afshinnia, F; Byun, J; Fort, PE; Gardner, TW; Kretzler, M; Looker, HC; Michailidis, G; Nelson, RG; Pennathur, S; Rajendiran, TM; Roger, JE; Shan, Y; Soni, T1
Dempsey, PC; Dunstan, DW; Grace, MS; Kingwell, BA; Meikle, PJ; Mellett, NA; Mundra, PA; Owen, N; Sethi, P; Weir, JM1
Furey, A; Likhodii, S; Liu, M; Randell, EW; Sun, G; Zhai, G; Zhang, W1
Auriola, S; Bergdahl, IA; Brunius, C; Hanhineva, K; Landberg, R; Lehtonen, M; Rolandsson, O; Shi, L1
Becher, S; Esch, P; Heiles, S1
Barbas, C; Ciborowski, M; Gil de la Fuente, A; Godzien, J; Kretowski, A; Otero, A; Siroka, J; Traldi, F1
Hu, C; Jia, W; Jiang, F; Wang, J; Wang, S; Yan, D; Zhang, R; Zhao, A; Zheng, X1
Fan, B; Guo, XL; Li, JJ; Zhang, P; Zheng, ZS1
Miyazawa, T; Nakagawa, K; Suzuki, K1
Bain, JR; Lowe, WL1
Adamski, J; Boeing, H; Drogan, D; Floegel, A; Pischon, T; Prehn, C; Schulze, MB; von Ruesten, A1
Adamski, J; Claussnitzer, M; Grallert, H; Hauner, H; Heier, M; Heukamp, I; Huth, C; Illig, T; Kastenmüller, G; Kirchhofer, A; Krug, S; Laumen, H; Lechner, A; Meisinger, C; Peters, A; Prehn, C; Römisch-Margl, W; Seissler, J; Then, C; Thorand, B; Wahl, S1
Acar, N; Berdeaux, O; Bretillon, L; Bron, AM; Cabaret, S; Creuzot-Garcher, CP; Grégoire, S; Isaïco, R; Koehrer, P; Saab, S1
He, J; Howard, BV; Hyun, N; Jones, D; Lee, ET; Tran, VT; Uppal, K; Yu, T; Zeng, D; Zhao, J; Zhu, Y1
Chiuve, SE; Hu, FB; Li, Y; Manson, JE; Qi, L; Wang, DD; Willett, WC1
Bacon, SD; Bergman, BC; Brozinick, JT; Bui, HH; D'Alessandro, A; Hansen, KC; Kerege, AA; Kiseljak-Vassiliades, K; Kuo, MS; Nemkov, T; Newsom, SA; Perreault, L; Sanders, P; Siddall, P; Strauss, AN; Thomas, M; Wei, T1
Walker, AK1
Dore, TM; Jesus, AR; Machuqueiro, M; Marques, AP; Rauter, AP; Vila-Viçosa, D1
Bao, S; Barter, PJ; Bonnet, DJ; Brown, BE; Curtiss, LK; Davies, MJ; Dusting, GJ; Jenkins, AJ; Lambert, G; Nobécourt, E; Puranik, R; Rye, KA; Tabet, F; Yan, L1
Adamski, J; Boeing, H; Drogan, D; Floegel, A; Fritsche, A; Häring, HU; Hrabě de Angelis, M; Illig, T; Joost, HG; Mühlenbruch, K; Peters, A; Pischon, T; Prehn, C; Roden, M; Schulze, MB; Stefan, N; Wang-Sattler, R; Yu, Z1
Adam, KP; Adamski, J; Camastra, S; Ferrannini, E; Gall, WE; Groop, L; Kastenmüller, G; Lyssenko, V; Mari, A; Milburn, MV; Nannipieri, M; Natali, A; Tuomi, T1
Jirak, R; Macasek, J; Tvrzicka, E; Vareka, T; Vecka, M; Zak, A; Zeman, M1
Cassagne, C; Diakou, V; Gin, H; Maneta-Peyret, L; Perret, AM; Poix, J; Vergnot, V1
Knight, JD; Miranker, AD1
Leiter, EH; Pan, HJ; Reifsnyder, P; Vance, DE; Xiao, Q1
Cai, H; Higuchi, O; Miyazawa, T; Mune, M; Nakagawa, K; Oak, JH; Oikawa, S; Otani, H; Tsuzuki, T1
Brosnan, JT; Brosnan, ME; Hall, B; Ratnam, S; Wijekoon, EP; Zeisel, SH1
Chen, YE; Leiter, EH; Lin, Y; Pan, HJ; Vance, DE1
Arsić, A; Blazencić Mladenović, V; Postić, M; Ristić Medić, D; Ristić, G; Ristić, V; Tepsić, J1
Mackness, B; Mackness, M; Mastorikou, M1
Frohman, MA; Huang, P1
Harada, AS; Lau, W1
Attia, N; Chaaba, R; Chanussot, F; Hamda, KB; Hammami, M; Hammami, S; Moulin, P; Nakbi, A; Smaoui, M1
Plehwe, WE; Shearman, RP; Storey, GN; Turtle, JR1
Betteridge, DJ; Cooper, MB; Freeman, DJ; Griffin, BA; Hales, CN; Ling, KL; Packard, CJ; Shepherd, J; Tan, KC1
Boisseau, MR; Claverie, M; Crockett, R; Freyburger, G; Gin, H; Lacape, G; Lardeau, D; Le Moigne, F; Seigneur, M1
Heintz, B; Hesse, K; Kirsten, R; Nelson, K; Nemeth, N; Oremek, G; Schneider, E1
Boku, A; Ochiai, S; Onuma, T; Takebe, K; Tamasawa, A; Tsutsui, M1
Driscoll, D; Ennis, W; Meneses, P1
Boisseau, MR; Cassagne, C; Freyburger, G; Gin, H; Labrouche, S1
Avignon, A; Bandyopadhyay, G; Farese, RV; Standaert, ML; Yamada, K1
Gromnatskiĭ, NI; Kirichenko, LL; Mel'chinskaia, EN1
Donner, M; Drouin, P; Meyer, L; Younsi, M; Zeghari, N; Ziegler, O1
Funakoshi, A; Hayashi, H; Ichikawa, M; Kanai, S; Miyasaka, K; Sato, Y1
Hirayama, Y; Ishigaki, Y; Miyazawa, T; Nagashima, T; Oikawa, S; Sekikawa, A; Tokita, Y; Yamada, R1
Moore, TR1
Curatola, G; Dousset, N; Ferretti, G; Solèra, ML; Taus, M; Valdiguie, P1
Frohlich, J; Godin, DV1

Reviews

5 review(s) available for phosphatidylcholines and Diabetes Mellitus, Adult-Onset

ArticleYear
SGLT2 Inhibition, Choline Metabolites, and Cardiometabolic Diseases: A Mediation Mendelian Randomization Study.
    Diabetes care, 2022, 11-01, Volume: 45, Issue:11

    Topics: Choline; Coronary Artery Disease; Diabetes Mellitus, Type 2; Genome-Wide Association Study; Glycine; Humans; Mendelian Randomization Analysis; Phosphatidylcholines; Polymorphism, Single Nucleotide; Risk Factors; Sodium-Glucose Transporter 2 Inhibitors

2022
Graduate Student Literature Review: A scoping review on the impact of consumption of dairy products on phosphatidylcholine and lysophosphatidylcholine in circulation and the liver in human studies and animal models.
    Journal of dairy science, 2023, Volume: 106, Issue:1

    Topics: Animals; Dairy Products; Diabetes Mellitus, Type 2; Diet; Humans; Liver; Lysophosphatidylcholines; Milk; Models, Animal; Phosphatidylcholines; Students; Yogurt

2023
Augmentation of blood lipid glycation and lipid oxidation in diabetic patients.
    Clinical chemistry and laboratory medicine, 2014, Jan-01, Volume: 52, Issue:1

    Topics: Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Erythrocytes; Glycation End Products, Advanced; Glycolipids; Glycosylation; Humans; Lipid Peroxidation; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Tandem Mass Spectrometry

2014
1-Carbon Cycle Metabolites Methylate Their Way to Fatty Liver.
    Trends in endocrinology and metabolism: TEM, 2017, Volume: 28, Issue:1

    Topics: Animals; Carbon Cycle; Diabetes Mellitus, Type 2; Fatty Liver; Humans; Lipogenesis; Phosphatidylcholines; S-Adenosylmethionine

2017
The potential for phospholipase D as a new therapeutic target.
    Expert opinion on therapeutic targets, 2007, Volume: 11, Issue:5

    Topics: Animals; Apoptosis; Cell Line, Tumor; Diabetes Mellitus, Type 2; Drug Delivery Systems; Endocytosis; Enzyme Inhibitors; Exocytosis; Gene Expression Regulation, Enzymologic; Humans; Mammals; Membrane Lipids; Neoplasm Proteins; Neoplasms; Organ Specificity; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Protein Isoforms; Protein Structure, Tertiary; Subcellular Fractions

2007

Trials

3 trial(s) available for phosphatidylcholines and Diabetes Mellitus, Adult-Onset

ArticleYear
Breaking Up Prolonged Sitting Alters the Postprandial Plasma Lipidomic Profile of Adults With Type 2 Diabetes.
    The Journal of clinical endocrinology and metabolism, 2017, 06-01, Volume: 102, Issue:6

    Topics: Aged; Cross-Over Studies; Diabetes Mellitus, Type 2; Diglycerides; Exercise; Female; Humans; Inflammation; Linear Models; Lipid Metabolism; Male; Mass Spectrometry; Middle Aged; Obesity; Overweight; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Plasmalogens; Postprandial Period; Posture; Sedentary Behavior; Triglycerides

2017
Novel metabolic markers for the risk of diabetes development in American Indians.
    Diabetes care, 2015, Volume: 38, Issue:2

    Topics: Adult; Biomarkers; Biphenyl Compounds; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Indians, North American; Insulin Resistance; Isoflavones; Logistic Models; Male; Metabolomics; Oligopeptides; Phosphatidylcholines; Prospective Studies; Risk Factors

2015
Polyenylphosphatidylcholine improves the lipoprotein profile in diabetic patients.
    International journal of clinical pharmacology and therapeutics, 1994, Volume: 32, Issue:2

    Topics: Administration, Oral; Adult; Aged; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hyperlipidemias; Male; Middle Aged; Phosphatidylcholines; Triglycerides

1994

Other Studies

58 other study(ies) available for phosphatidylcholines and Diabetes Mellitus, Adult-Onset

ArticleYear
Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes.
    Annals of clinical and translational neurology, 2022, Volume: 9, Issue:9

    Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Fatty Acids, Nonesterified; Female; Humans; Lipidomics; Lysophosphatidylcholines; Male; Middle Aged; Phosphatidylcholines; Retrospective Studies

2022
Metabolomic comparison followed by cross-validation of enzyme-linked immunosorbent assay to reveal potential biomarkers of diabetic retinopathy in Chinese with type 2 diabetes.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Aged; Biomarkers; Carnitine; Case-Control Studies; Chenodeoxycholic Acid; China; Citrulline; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Eicosapentaenoic Acid; Enzyme-Linked Immunosorbent Assay; Humans; Metabolomics; Phosphatidylcholines

2022
Specific triacylglycerol, diacylglycerol, and lyso-phosphatidylcholine species for the prediction of type 2 diabetes: a ~ 16-year prospective study in Chinese.
    Cardiovascular diabetology, 2022, 11-05, Volume: 21, Issue:1

    Topics: Animals; Case-Control Studies; China; Diabetes Mellitus, Type 2; Diglycerides; Mice; Models, Statistical; Phosphatidylcholines; Prediabetic State; Prognosis; Prospective Studies; Triglycerides

2022
Gestational Diabetes Mellitus, Postpartum Lipidomic Signatures, and Subsequent Risk of Type 2 Diabetes: A Lipidome-Wide Association Study.
    Diabetes care, 2023, 06-01, Volume: 46, Issue:6

    Topics: Adult; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Humans; Infant; Lipidomics; Male; Phosphatidylcholines; Postpartum Period; Pregnancy; Prospective Studies

2023
Phosphatidylcholine and its relation to apolipoproteins A-1 and B changes after Roux-en-Y gastric bypass: a cohort study.
    Lipids in health and disease, 2019, Sep-05, Volume: 18, Issue:1

    Topics: Adult; Apolipoprotein A-I; Apolipoprotein B-100; Cholesterol, LDL; Cholesterol, VLDL; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gastric Bypass; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Lipid Metabolism; Male; Middle Aged; Obesity, Morbid; Phosphatidylcholines; Weight Loss

2019
Metabolomics profiles associated with HbA1c levels in patients with type 2 diabetes.
    PloS one, 2019, Volume: 14, Issue:11

    Topics: Aged; Amino Acids; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose; Glycated Hemoglobin; Glycine; Hexoses; Humans; Insulin Resistance; Male; Metabolomics; Middle Aged; Phosphatidylcholines; Valine

2019
Effectiveness of phosphatidylcholine in alleviating steatosis in patients with non-alcoholic fatty liver disease and cardiometabolic comorbidities (MANPOWER study).
    BMJ open gastroenterology, 2020, Volume: 7, Issue:1

    Topics: Adult; Comorbidity; Diabetes Mellitus, Type 2; Humans; Hypertension; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Prevalence; Prospective Studies; Workforce

2020
Dietary intake of choline and phosphatidylcholine and risk of type 2 diabetes in men: The Kuopio Ischaemic Heart Disease Risk Factor Study.
    European journal of nutrition, 2020, Volume: 59, Issue:8

    Topics: Choline; Diabetes Mellitus, Type 2; Diet; Eating; Finland; Heart Disease Risk Factors; Humans; Male; Phosphatidylcholines; Prospective Studies; Risk Factors

2020
Effectiveness of phosphatidylcholine as adjunctive therapy in improving liver function tests in patients with non-alcoholic fatty liver disease and metabolic comorbidities: real-life observational study from Russia.
    BMJ open gastroenterology, 2020, Volume: 7, Issue:1

    Topics: Adult; Comorbidity; Diabetes Mellitus, Type 2; Humans; Liver Function Tests; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Russia

2020
Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice.
    Journal of nanobiotechnology, 2020, Apr-28, Volume: 18, Issue:1

    Topics: Administration, Oral; Animals; Blood Glucose; Cholic Acid; Diabetes Mellitus, Type 2; Drug Carriers; Exenatide; Gastrointestinal Tract; Glycated Hemoglobin; Half-Life; Hypoglycemic Agents; Insulin-Secreting Cells; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Nanoparticles; Permeability; Phosphatidylcholines; Zein

2020
Exogenous natural EPA-enriched phosphatidylcholine and phosphatidylethanolamine ameliorate lipid accumulation and insulin resistance
    Food & function, 2020, Sep-23, Volume: 11, Issue:9

    Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Eicosapentaenoic Acid; Humans; Insulin Resistance; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Phosphatidylcholines; PPAR alpha; PPAR gamma; Sea Cucumbers

2020
Association of cardiac autonomic dysfunction with higher levels of plasma lipid metabolites in recent-onset type 2 diabetes.
    Diabetologia, 2021, Volume: 64, Issue:2

    Topics: Adult; Autonomic Nervous System Diseases; Carnitine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Dyslipidemias; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Heart Rate; Humans; Insulin Resistance; Lipid Metabolism; Lipidomics; Lysophosphatidylcholines; Male; Middle Aged; Obesity; Phosphatidylcholines; Sphingomyelins; Young Adult

2021
Early Signs of Atherogenic Features in the HDL Lipidomes of Normolipidemic Patients Newly Diagnosed with Type 2 Diabetes.
    International journal of molecular sciences, 2020, Nov-22, Volume: 21, Issue:22

    Topics: Aged; Atherosclerosis; Cholesterol, HDL; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Lipidomics; Lipoproteins, HDL; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Sphingomyelins; Triglycerides

2020
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance.
    Nature communications, 2021, 01-11, Volume: 12, Issue:1

    Topics: Adipose Tissue; Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Dyslipidemias; Epithelial Cells; Exosomes; Fatty Liver; Feces; Gene Expression Regulation; Glucose Intolerance; Green Fluorescent Proteins; Humans; Insulin; Insulin Resistance; Interleukin-6; Intestines; Lipids; Liver; Macrophage Activation; Mice, Inbred C57BL; Phosphatidylcholines; Receptors, Aryl Hydrocarbon; Signal Transduction; Tetraspanin 30; Tumor Necrosis Factor-alpha; Up-Regulation

2021
Localized increases in CEPT1 and ATGL elevate plasmalogen phosphatidylcholines in HDLs contributing to atheroprotective lipid profiles in hyperglycemic GCK-MODY.
    Redox biology, 2021, Volume: 40

    Topics: Diabetes Mellitus, Type 2; Glucokinase; Humans; Mutation; Phosphatidylcholines; Plasmalogens

2021
Lipid profiles of patients with manifest coronary versus peripheral atherosclerosis - Is there a difference?
    Journal of internal medicine, 2021, Volume: 290, Issue:6

    Topics: Atherosclerosis; Ceramides; Coronary Artery Disease; Diabetes Mellitus, Type 2; Humans; Lipids; Lipoproteins; Peripheral Arterial Disease; Phosphatidylcholines; Risk Factors

2021
Diminished retinal complex lipid synthesis and impaired fatty acid β-oxidation associated with human diabetic retinopathy.
    JCI insight, 2021, 10-08, Volume: 6, Issue:19

    Topics: Adult; Aged; American Indian or Alaska Native; Arizona; Black or African American; Carnitine; Case-Control Studies; Ceramides; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Diglycerides; Disease Progression; Esters; Female; Hispanic or Latino; Humans; Lipidomics; Male; Mass Spectrometry; Middle Aged; Mitochondria; Phosphatidylcholines; Retina; Triglycerides; White People

2021
Hyperglycemia-related advanced glycation end-products is associated with the altered phosphatidylcholine metabolism in osteoarthritis patients with diabetes.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Aged; Biomarkers; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Glycation End Products, Advanced; Humans; Hyperglycemia; Lysine; Male; Middle Aged; Osteoarthritis; Phosphatidylcholines; Synovial Fluid; Tandem Mass Spectrometry

2017
Plasma metabolites associated with type 2 diabetes in a Swedish population: a case-control study nested in a prospective cohort.
    Diabetologia, 2018, Volume: 61, Issue:4

    Topics: Adult; Case-Control Studies; Chromatography, Liquid; Diabetes Mellitus, Type 2; Disease Progression; Female; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Phosphatidylcholines; Plasma; Prospective Studies; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Sweden

2018
Relative Quantification of Phosphatidylcholine sn-Isomers Using Positive Doubly Charged Lipid-Metal Ion Complexes.
    Analytical chemistry, 2018, 10-02, Volume: 90, Issue:19

    Topics: Animals; Chromatography, High Pressure Liquid; Coordination Complexes; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids; Female; Ions; Iron; Isomerism; Limit of Detection; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization; Ultraviolet Rays

2018
Characterization and annotation of oxidized glycerophosphocholines for non-targeted metabolomics with LC-QTOF-MS data.
    Analytica chimica acta, 2018, Dec-11, Volume: 1037

    Topics: Chromatography, Liquid; Databases, Factual; Diabetes Mellitus, Type 2; Humans; Mass Spectrometry; Metabolomics; Molecular Structure; Oxidation-Reduction; Phosphatidylcholines

2018
Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach.
    Cardiovascular diabetology, 2019, 01-11, Volume: 18, Issue:1

    Topics: Adult; Aged; Aspartic Acid; Biomarkers; Carotid Artery Diseases; Carotid Intima-Media Thickness; Case-Control Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Glutamic Acid; Haptoglobins; Humans; Male; Metabolomics; Middle Aged; Phosphatidylcholines

2019
The efficacy of saxagliptin in T2DM patients with non-alcoholic fatty liver disease: preliminary data.
    Revista da Associacao Medica Brasileira (1992), 2019, Volume: 65, Issue:1

    Topics: Adamantane; Blood Glucose; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptides; Female; Humans; Hypoglycemic Agents; Insulin Resistance; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sulfonylurea Compounds; Treatment Outcome

2019
"Prediction is very hard, especially about the future": new biomarkers for type 2 diabetes?
    Diabetes, 2013, Volume: 62, Issue:5

    Topics: Animals; Diabetes Mellitus, Type 2; Female; Glucose Metabolism Disorders; Humans; Hydroxybutyrates; Insulin Resistance; Male; Phosphatidylcholines

2013
Variation of serum metabolites related to habitual diet: a targeted metabolomic approach in EPIC-Potsdam.
    European journal of clinical nutrition, 2013, Volume: 67, Issue:10

    Topics: Adult; Amino Acids; Carnitine; Chronic Disease; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diet; Feeding Behavior; Female; Hexoses; Humans; Male; Metabolome; Metabolomics; Middle Aged; Phosphatidylcholines; Risk Factors; Surveys and Questionnaires

2013
Plasma metabolomics reveal alterations of sphingo- and glycerophospholipid levels in non-diabetic carriers of the transcription factor 7-like 2 polymorphism rs7903146.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Alleles; Blood Glucose; Diabetes Mellitus, Type 2; Genotype; Glucose Tolerance Test; Glycerophospholipids; Humans; Insulin; Male; Metabolome; Metabolomics; Middle Aged; Phosphatidylcholines; Polymorphism, Genetic; Sphingomyelins; Transcription Factor 7-Like 2 Protein

2013
Erythrocyte phospholipid and polyunsaturated fatty acid composition in diabetic retinopathy.
    PloS one, 2014, Volume: 9, Issue:9

    Topics: Adult; Aged; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Erythrocyte Membrane; Fatty Acids, Unsaturated; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Plasmalogens; Severity of Illness Index

2014
Dietary phosphatidylcholine intake and type 2 diabetes in men and women.
    Diabetes care, 2015, Volume: 38, Issue:2

    Topics: Diabetes Mellitus, Type 2; Diet; Feeding Behavior; Female; Humans; Male; Phosphatidylcholines; Risk Factors

2015
Skeletal muscle phosphatidylcholine and phosphatidylethanolamine are related to insulin sensitivity and respond to acute exercise in humans.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Jun-01, Volume: 120, Issue:11

    Topics: Adult; Athletes; Blood Glucose; Diabetes Mellitus, Type 2; Exercise; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxygen Consumption; Phosphatidylcholines; Phosphatidylethanolamines

2016
Targeting Type 2 Diabetes with C-Glucosyl Dihydrochalcones as Selective Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Synthesis and Biological Evaluation.
    Journal of medicinal chemistry, 2017, 01-26, Volume: 60, Issue:2

    Topics: Chalcones; Diabetes Mellitus, Type 2; Glucosides; HEK293 Cells; Humans; Membranes, Artificial; Molecular Docking Simulation; Phosphatidylcholines; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors

2017
Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I.
    Arteriosclerosis, thrombosis, and vascular biology, 2010, Volume: 30, Issue:4

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Apolipoprotein A-I; Carotid Arteries; Carotid Artery Injuries; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Glycosylation; Humans; I-kappa B Proteins; Inflammation; Infusions, Parenteral; Intercellular Adhesion Molecule-1; Lipoproteins, HDL; Neutrophil Infiltration; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphatidylcholines; Phosphorylation; Protein Processing, Post-Translational; Pyruvaldehyde; Rabbits; Reactive Oxygen Species; Time Factors; Vascular Cell Adhesion Molecule-1

2010
Identification of serum metabolites associated with risk of type 2 diabetes using a targeted metabolomic approach.
    Diabetes, 2013, Volume: 62, Issue:2

    Topics: Adult; Biomarkers; Diabetes Mellitus, Type 2; Female; Glycine; Hexoses; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Metabolomics; Middle Aged; Phenylalanine; Phosphatidylcholines; Risk; Serum; Sphingomyelins

2013
Early metabolic markers of the development of dysglycemia and type 2 diabetes and their physiological significance.
    Diabetes, 2013, Volume: 62, Issue:5

    Topics: Adult; Animals; Biomarkers; Cell Line; Cohort Studies; Diabetes Mellitus, Type 2; Early Diagnosis; Female; Follow-Up Studies; Glucose Metabolism Disorders; Humans; Hydroxybutyrates; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Male; Middle Aged; Phosphatidylcholines; Prospective Studies; Rats; ROC Curve

2013
Plasma fatty acid profile in depressive disorder resembles insulin resistance state.
    Neuro endocrinology letters, 2012, Volume: 33 Suppl 2

    Topics: Adult; Aged; Cardiovascular Diseases; Cholesterol Esters; Depressive Disorder; Diabetes Mellitus, Type 2; Fatty Acids, Monounsaturated; Fatty Acids, Unsaturated; Female; Humans; Insulin Resistance; Linoleoyl-CoA Desaturase; Male; Middle Aged; Oxidative Stress; Phosphatidylcholines; Risk Factors; Stearoyl-CoA Desaturase

2012
Anti-phospholipid antibodies in diabetes mellitus.
    Clinical chemistry and laboratory medicine, 2002, Volume: 40, Issue:6

    Topics: Adult; Antibodies, Antiphospholipid; Blood Glucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Enzyme-Linked Immunosorbent Assay; Female; Glycated Hemoglobin; Humans; Male; Middle Aged; Phosphatidylcholines; Phosphatidylinositols; Reference Values

2002
Phospholipid catalysis of diabetic amyloid assembly.
    Journal of molecular biology, 2004, Aug-27, Volume: 341, Issue:5

    Topics: Amino Acid Sequence; Amyloid; Animals; Diabetes Mellitus, Type 2; Female; Humans; Islet Amyloid Polypeptide; Lipid Bilayers; Liposomes; Molecular Sequence Data; Peptides; Phosphatidylcholines; Phosphatidylglycerols; Protein Binding; Sequence Alignment

2004
Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes.
    Diabetes, 2005, Volume: 54, Issue:6

    Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Female; Hypoglycemic Agents; Liver; Male; Mice; Mice, Congenic; Pharmacogenetics; Phenotype; Phosphatidylcholines; Rosiglitazone; Thiazolidinediones

2005
Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes.
    Journal of lipid research, 2005, Volume: 46, Issue:11

    Topics: Adult; Aged; Chromatography, Liquid; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Lipids; Mass Spectrometry; Middle Aged; Models, Chemical; Oxidative Stress; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Reactive Oxygen Species

2005
Homocysteine metabolism in ZDF (type 2) diabetic rats.
    Diabetes, 2005, Volume: 54, Issue:11

    Topics: Animals; Betaine; Cells, Cultured; Diabetes Mellitus, Type 2; Gene Expression Regulation, Enzymologic; Hepatocytes; Homocysteine; Insulin Resistance; Liver; Methionine; Phosphatidylcholines; Rats; Rats, Zucker; RNA, Messenger

2005
Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism.
    Vascular pharmacology, 2006, Volume: 45, Issue:1

    Topics: Animals; Cardiolipins; Cardiovascular System; Choline-Phosphate Cytidylyltransferase; Crosses, Genetic; Diabetes Mellitus, Type 2; Disease Models, Animal; Fatty Liver; Gene Expression Regulation; Hypoglycemic Agents; Liver; Male; Mice; Mice, Inbred NOD; Mice, Obese; Mitochondria, Heart; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; PPAR gamma; Rosiglitazone; Thiazolidinediones

2006
Effects of soybean D-LeciVita product on serum lipids and fatty acid composition in type 2 diabetic patients with hyperlipidemia.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2006, Volume: 16, Issue:6

    Topics: Adult; Aged; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Dietary Supplements; Fatty Acids; Female; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Phosphatidylcholines; Soybean Proteins

2006
Defective metabolism of oxidized phospholipid by HDL from people with type 2 diabetes.
    Diabetes, 2006, Volume: 55, Issue:11

    Topics: Adult; Aryldialkylphosphatase; Coronary Disease; Diabetes Mellitus, Type 2; Gene Frequency; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Polymorphism, Genetic; Reference Values; Sequence Deletion

2006
Successful treatment and limb salvage of mucor necrotizing fasciitis after kidney transplantation with posaconazole.
    Hawaii medical journal, 2007, Volume: 66, Issue:3

    Topics: Alcaligenes; Amphotericin B; Amputation, Surgical; Antifungal Agents; Cefazolin; Combined Modality Therapy; Debridement; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Combinations; Drug Resistance, Multiple, Fungal; Escherichia coli Infections; Fatal Outcome; Fluconazole; Gangrene; Graft Rejection; Gram-Negative Bacterial Infections; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney Transplantation; Leg; Leg Ulcer; Male; Middle Aged; Mucor; Mucormycosis; Penicillanic Acid; Phosphatidylcholines; Phosphatidylglycerols; Piperacillin; Postoperative Complications; Pyrimidines; Renal Dialysis; Reoperation; Sepsis; Skin Transplantation; Tazobactam; Triazoles; Voriconazole

2007
Increased phospholipid transfer protein activity associated with the impaired cellular cholesterol efflux in type 2 diabetic subjects with coronary artery disease.
    The Tohoku journal of experimental medicine, 2007, Volume: 213, Issue:2

    Topics: Adult; Animals; Apolipoprotein A-I; Apolipoproteins B; Biological Transport; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line, Tumor; Cholesterol; Cholesterol, HDL; Cholesterol, VLDL; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Liposomes; Liver Neoplasms, Experimental; Male; Middle Aged; Phosphatidylcholines; Phospholipid Transfer Proteins; Rats; Triglycerides

2007
Outcome of pregnancy complicated by diabetes: experience with 232 patients in a 4 year period.
    Diabetes research (Edinburgh, Scotland), 1984, Volume: 1, Issue:2

    Topics: Abnormalities, Multiple; Amniotic Fluid; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Fetal Blood; Gestational Age; Humans; Hydrogen-Ion Concentration; Hypocalcemia; Hypoglycemia; Infant Mortality; Infant, Newborn; Infant, Newborn, Diseases; Phosphatidylcholines; Pregnancy; Pregnancy in Diabetics; Respiratory Distress Syndrome, Newborn; Sphingomyelins

1984
Fasting and postprandial determinants for the occurrence of small dense LDL species in non-insulin-dependent diabetic patients with and without hypertriglyceridaemia: the involvement of insulin, insulin precursor species and insulin resistance.
    Atherosclerosis, 1995, Volume: 113, Issue:2

    Topics: Case-Control Studies; Centrifugation, Density Gradient; Diabetes Mellitus, Type 2; Eating; Fasting; Humans; Hypertriglyceridemia; Insulin; Insulin Resistance; Lipase; Lipoproteins, LDL; Male; Middle Aged; Multivariate Analysis; Phosphatidylcholines; Proinsulin; Radioimmunoassay

1995
Serum fatty acid profiles in type I and type II diabetes: metabolic alterations of fatty acids of the main serum lipids.
    Diabetes research and clinical practice, 1994, Volume: 23, Issue:3

    Topics: Adult; Aged; Cholesterol; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Male; Middle Aged; Phosphatidylcholines; Sphingomyelins; Triglycerides

1994
Lipid composition of platelets in patients with non-insulin-dependent diabetes mellitus: studies before and after treatment of diabetes.
    Diabetic medicine : a journal of the British Diabetic Association, 1994, Volume: 11, Issue:3

    Topics: Blood Platelets; Cholesterol; Diabetes Mellitus, Type 2; Humans; Insulin; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Reference Values; Sphingomyelins; Triglycerides

1994
Human sciatic nerve phospholipid profiles from non-diabetes mellitus, non-insulin-dependent diabetes mellitus and insulin-dependent diabetes mellitus individuals. A 31P NMR spectroscopy study.
    The International journal of biochemistry, 1994, Volume: 26, Issue:6

    Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phosphatidylserines; Phospholipids; Plasmalogens; Sciatic Nerve; Sphingomyelins

1994
Changes in phospholipid composition of blood cell membranes (erythrocyte, platelet, and polymorphonuclear) in different types of diabetes--clinical and biological correlations.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:1

    Topics: Adult; Aged; Blood Platelets; Cell Membrane; Densitometry; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Female; Humans; Male; Middle Aged; Neutrophils; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Phospholipids; Sphingomyelins

1996
The phosphatidylinositol 3-kinase inhibitor, wortmannin, inhibits insulin-induced activation of phosphatidylcholine hydrolysis and associated protein kinase C translocation in rat adipocytes.
    The Biochemical journal, 1996, Feb-01, Volume: 313 ( Pt 3)

    Topics: Adipose Tissue; Androstadienes; Animals; Biological Transport, Active; Diabetes Mellitus, Type 2; Enzyme Activation; Enzyme Inhibitors; Hydrolysis; In Vitro Techniques; Indoles; Insulin; Isoenzymes; Male; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Protein Kinase C; Rats; Wortmannin

1996
[Hypolipidemic effects of alisat and lipostabil in patients with diabetes mellitus].
    Terapevticheskii arkhiv, 2000, Volume: 72, Issue:8

    Topics: Adult; Aged; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Diabetes Mellitus, Type 2; Fat Emulsions, Intravenous; Female; Garlic; Humans; Hyperlipidemias; Male; Middle Aged; Phosphatidylcholines; Plants, Medicinal; Triglycerides

2000
Adipocyte and erythrocyte plasma membrane phospholipid composition and hyperinsulinemia: a study in nondiabetic and diabetic obese women.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2000, Volume: 24, Issue:12

    Topics: Adipocytes; Adult; Body Mass Index; Cell Membrane; Chromatography, High Pressure Liquid; Diabetes Mellitus; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Fasting; Female; Homeostasis; Humans; Hyperinsulinism; Insulin; Insulin Resistance; Middle Aged; Obesity; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Regression Analysis; Sphingomyelins

2000
Increased lymphatic lipid transport in genetically diabetic obese rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 282, Issue:1

    Topics: Animals; Bile Acids and Salts; Body Weight; Carrier Proteins; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy Intake; Fistula; Hypoglycemic Agents; Lymphatic System; Male; Obesity; Phosphatidylcholines; Physical Conditioning, Animal; Rats; Rats, Inbred OLETF; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone

2002
Increase of serum phosphatidylcholine hydroperoxide dependent on glycemic control in type 2 diabetic patients.
    Diabetes research and clinical practice, 2002, Volume: 56, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Lipoproteins, HDL; Male; Middle Aged; Phosphatidylcholines; Phospholipids; Reference Values; Triglycerides

2002
A comparison of amniotic fluid fetal pulmonary phospholipids in normal and diabetic pregnancy.
    American journal of obstetrics and gynecology, 2002, Volume: 186, Issue:4

    Topics: Amniocentesis; Amniotic Fluid; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Female; Fetal Organ Maturity; Gestational Age; Humans; Linear Models; Lung; Odds Ratio; Phosphatidylcholines; Phosphatidylglycerols; Phosphatidylinositols; Phospholipids; Pregnancy; Pregnancy in Diabetics; Racial Groups; Sphingomyelins

2002
Lower susceptibility of low density lipoprotein to in vitro oxidation in diabetic patients.
    Biochemistry international, 1992, Volume: 28, Issue:5

    Topics: Adult; Copper; Copper Sulfate; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diphenylhexatriene; Female; Fluorescence Polarization; Humans; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Phosphatidylcholines; Trinitrobenzenesulfonic Acid

1992
Erythrocyte membrane alterations and plasma lipids in patients with chylomicronemia and in Tangier disease.
    Clinical biochemistry, 1986, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Apolipoprotein C-II; Apolipoproteins C; Ca(2+) Mg(2+)-ATPase; Chylomicrons; Diabetes Mellitus, Type 2; Erythrocyte Membrane; Humans; Hypolipoproteinemias; Lipids; Lipoprotein Lipase; Male; Middle Aged; Phosphatidylcholines; Sodium-Potassium-Exchanging ATPase; Sphingomyelins; Tangier Disease

1986