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phosphatidylcholines and Chemical and Drug Induced Liver Injury

phosphatidylcholines has been researched along with Chemical and Drug Induced Liver Injury in 71 studies

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199027 (38.03)18.7374
1990's12 (16.90)18.2507
2000's11 (15.49)29.6817
2010's17 (23.94)24.3611
2020's4 (5.63)2.80

Authors

AuthorsStudies
Liu, Q; Liu, R; Lu, L; Pu, Y; Wang, S; Yin, L; Zhang, H; Zhang, Y; Zhao, C; Zhou, Q1
Bednarz, H; Ernst, R; Fatangare, A; Giampà, M; Kampa, JM; Niehaus, K; Riefke, B; Sahin, M; Slopianka, M1
Han, X; Lei, X; Li, J; Liu, L; Mao, Y; Qian, Y; Tang, J; Wang, Y; Xu, Q; Zeng, M; Zhang, J; Zhong, W1
Du, S; Jin, S; Liu, M; Yan, H1
Li, CM; Li, XB; Liu, XL; Ma, SC; Mao, YM; Ming, YN; Wang, XL; Wang, ZY; Zhang, JY1
Chenggang, Z; Dongchen, L; Jianjun, L; Liansheng, W; Naiqiong, W; Qian, D; Yanjun, Z; Ying, G; Yuanlin, G; Zhanying, H1
Li, Q; Ma, Y; Mu, X; Song, L; Wang, D; Yin, R; Zhao, X1
Athmouni, K; Ayadi, H; El Feki, A; Mkadmini Hammi, K1
Burkova, VN; Korshunov, DA; Udut, VV; Vaizova, OE; Vengerovskiĭ, AI1
Inafuku, A; Inafuku, M; Nagao, K; Oku, H; Taira, N; Toda, T; Yanagita, T1
Dygai, AM; Udut, VV; Vengerovsky, AI1
Adewoles, IF; Irabor, AE; Kuti, MA; Ogunbode, O; Otegbayo, JA1
Cherenkov, VG; Petrov, AB; Strozhenkov, MM; Vasil'eva, TM1
Cao, H; Chen, D; Lu, J; Ma, J; Su, X; Sun, H; Wang, Y; Yang, X; Yu, J; Zhu, C1
Kim, S; Kwon, J; Na, JY; Song, K1
Kamei, M; Kimura, F; Miyazawa, T; Nakagawa, K; Suzuki, K; Yamamoto, T1
Cai, L; He, K; Liu, H; Shi, Q; Woolf, TF1
Dvornichenko, VV; Morikov, DD; Morikova, EG1
Goda, K; Kobayashi, A; Maekawa, K; Saito, K; Saito, Y; Sugai, S; Yamada, N1
Chamulitrat, W; Pathil, A; Stremmel, W; Warth, A1
Bukshuk, AA; Maslovskiĭ, LV; Minushkin, ON1
Akhundzhanova, LL; Aripov, OA; Khalimbetov, GS1
PETZOLD, H; ROSAM, E1
DELUTTEROTTI, A; SARTORI, S; VALAGUSSA, L1
Estany, C; Gómez, L; Martí, JM; Martino, R; Sierra, J; Subirà, M1
Chiji, H; Fukushima, M; Han, KH; Lee, CH; Nakano, M; Ohba, K; Sekikawa, M; Shimada, K1
Avorn, J; Fischer, MA; Rubin, RH; Winkelmayer, WC1
Leather, H; Wingard, JR1
Harada, E; Imanaka, H; Ishikado, A; Makino, T; Takeuchi, T1
Afifi, NN; El-Samaligy, MS; Mahmoud, EA1
Gantait, A; Maiti, K; Mukherjee, K; Mukherjee, PK; Saha, BP1
Agellon, LB; Li, Z; Vance, DE1
Chamilos, G; Chemaly, R; Kontoyiannis, DP; Lewis, RE; Luna, M; Raad, II1
Horning, MG; Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV1
Boyle, M; Mulligan, K; Neubauer, KA; O'Neill, D; Royston, VH; Scott, M; Surmon, DJ; Wilcock, GK1
Gauthier, L; Gauthier, S1
Abakumova, OIu; Fedorova, LM; Gavril'chak, AV; Karagiulian, SR; Kliashchitskiĭ, BA; Kovaleva, GG; Kutsenko, NG; Li, VS; Mitina, VKh; Podobed, OV; Popov, AA; Shekhter, AB1
Grundy, SM; Tatò, F; Vega, GL1
Hirano, K; Murakami, T; Nagamura, Y1
Glasa, J; Hlavatý, I; Holomán, J; Lukácsová, M; Prachar, V; Veningerová, M1
Saratikov, AS; Vengerovskiĭ, AI1
Philips, DL; Sallah, S; Sallah, W; Semelka, RC; Vainright, JR1
Kolbasov, SE; Lebedev, VP; Melikhova, MV; Stroĭkova, GV; Zamuruev, ON1
Bonorris, GG; Marks, JW; Pearlman, BJ; Schoenfield, LJ1
Kuiken, LB; Ragland, JB; Sabesin, SM1
Goldstein, LI; Schoenfield, LJ1
Bartsch, GG; Gerber, GB1
Bartsch, GG; Deroo, J; Gerber, GB1
Lohmann, J; Rauen, HM; Schriewer, H1
Bartsch, GG; Brachtel, D; Gallenkamp, H; Löhr, JP; Richter, E1
Conti, M; Magistretti, MJ; Malandrino, S1
Aripov, AN; Atabekov, AG; Dombrovskaya, NV; Fesenko, LM; Gagel'gans, AI; Gizatullina, ZZ; Mokhova, EN1
Chatellier, G; Lacomblez, L1
Wendel, A; Werner, C1
Put, A; Samochowiec, L; Wójcicki, J; Wyczarska-Szok, K1
Saratikov, AS; Sedykh, IM; Vengerovskiĭ, AI1
Archakov, AI; Dobrynina, OV; Shatinina, SZ1
Chuchalin, VS; Paul's, OV; Saratikov, AS; Vengerovskiĭ, AI1
Drogovoz, SM; Porokhniak, LA; Rogozhin, BA1
Maiwald, L1
Costanzo, V; Granata, M; Lazzara, A; Maucceri, G1
Skakun, NP; Stepanova, NIu1
Campbell, TC; Hayes, JR1
Oberdisse, E; von Lehmann, V1
Sgoutas, DS1
Betzing, H; Lekim, D1
Rauen, HM; Schriewer, H2
Kattermann, R; Wolfrum, DI1
Edwards, KD; Galli, C; Paoletti, R; Usardi, MM1
Shimizu, Y1

Reviews

4 review(s) available for phosphatidylcholines and Chemical and Drug Induced Liver Injury

ArticleYear
What have we learned from the THA trials to facilitate testing of new AChE inhibitors.
    Progress in brain research, 1993, Volume: 98

    Topics: Alzheimer Disease; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Diseases; Humans; Phosphatidylcholines; Psychological Tests; Research Design; Tacrine; Treatment Outcome

1993
Gallstone dissolution--a progress report.
    Clinics in gastroenterology, 1979, Volume: 8, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Contraceptives, Oral, Synthetic; Deoxycholic Acid; Diarrhea; Enterohepatic Circulation; Estrogens; Female; Gallstones; Humans; Liver; Male; Phosphatidylcholines; Pregnancy; Recurrence; Risk

1979
Gallstones: pathogenesis and medical treatment.
    Advances in internal medicine, 1975, Volume: 20

    Topics: Adult; Animals; Arizona; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Fasting; Female; Guinea Pigs; Humans; Indians, North American; Liver; Male; Middle Aged; Minnesota; Phosphatidylcholines

1975
Role of nutrition in the drug-metabolizing enzyme system.
    Pharmacological reviews, 1974, Volume: 26, Issue:3

    Topics: Ascorbic Acid Deficiency; Calcium; Carbohydrates; Carcinogens; Catalysis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dietary Proteins; Fatty Acids; Humans; Iron Deficiencies; Kinetics; Lipids; Lipotropic Agents; Liver; Magnesium Deficiency; Mixed Function Oxygenases; Mutagens; Nicotinic Acids; Nutritional Physiological Phenomena; Oxidoreductases; Pharmaceutical Preparations; Phenobarbital; Phosphatidylcholines; Protein Deficiency; Riboflavin Deficiency; Thiamine Deficiency; Trace Elements; Vitamin A Deficiency

1974

Trials

5 trial(s) available for phosphatidylcholines and Chemical and Drug Induced Liver Injury

ArticleYear
A Multicenter and Randomized Controlled Trial of Bicyclol in the Treatment of Statin-Induced Liver Injury.
    Medical science monitor : international medical journal of experimental and clinical research, 2017, Dec-04, Volume: 23

    Topics: Adult; Aged; Alanine Transaminase; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Middle Aged; Phosphatidylcholines

2017
Livolin ameliorates elevations in alanine transaminase in HIV infected patients commencing highly active antiretroviral therapy.
    African journal of medicine and medical sciences, 2012, Volume: 41, Issue:4

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Phosphatidylcholines; Treatment Outcome; Vitamin B Complex; Vitamin E; Young Adult

2012
[Possibilities of remaxol in prevention of toxic hepatitis during chemotherapy for cancer patients].
    Voprosy onkologii, 2013, Volume: 59, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neoplasms; Patient Selection; Phosphatidylcholines; Protective Agents; Succinates; Treatment Outcome

2013
Low-dose amphotericin B lipid complex vs. conventional amphotericin B for empirical antifungal therapy of neutropenic fever in patients with hematologic malignancies--a randomized, controlled trial.
    European journal of haematology, 2004, Volume: 72, Issue:5

    Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Drug Combinations; Female; Fever of Unknown Origin; Hematologic Neoplasms; Humans; Hypokalemia; Immunocompromised Host; Incidence; Kidney Diseases; Male; Middle Aged; Mycoses; Neutropenia; Peripheral Blood Stem Cell Transplantation; Phosphatidylcholines; Phosphatidylglycerols; Treatment Outcome

2004
Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Français d'Etude de la Tetrahydroaminoacridine.
    BMJ (Clinical research ed.), 1990, Feb-24, Volume: 300, Issue:6723

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aminoacridines; Behavior; Chemical and Drug Induced Liver Injury; Cognition; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multicenter Studies as Topic; Phosphatidylcholines; Psychological Tests; Randomized Controlled Trials as Topic; Tacrine

1990

Other Studies

62 other study(ies) available for phosphatidylcholines and Chemical and Drug Induced Liver Injury

ArticleYear
Lipid metabolism disorders contribute to hepatotoxicity of ICR mice induced by nitrosamines exposure.
    Environment international, 2022, Volume: 167

    Topics: Animals; Chemical and Drug Induced Liver Injury; Fatty Acids; Lipid Metabolism; Lipid Metabolism Disorders; Liver; Mice; Mice, Inbred ICR; Nitrosamines; Phosphatidylcholines; Phosphatidylethanolamines

2022
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model.
    Toxicology letters, 2020, Jun-01, Volume: 325

    Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Lipid Metabolism; Liver; Male; Mass Spectrometry; Organ Size; Phosphatidylcholines; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation

2020
Exploring the efficacy and safety of polyene phosphatidylcholine for treatment of drug-induced liver injury using the Roussel Uclaf causality assessment method: a propensity score matching comparison.
    The Journal of international medical research, 2021, Volume: 49, Issue:8

    Topics: Chemical and Drug Induced Liver Injury; Humans; Phosphatidylcholines; Propensity Score; Retrospective Studies

2021
Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jun-15, Volume: 104

    Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Liberation; Kidney; Liposomes; Liver; Male; Matrines; Mice; Myocardium; Phosphatidylcholines; Protective Agents; Quinolizines; Spleen; Tissue Distribution

2017
Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice.
    Lipids in health and disease, 2017, Aug-14, Volume: 16, Issue:1

    Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Choline Kinase; Chromatography, Liquid; Gene Expression Regulation; Hepatocytes; Injections, Intraperitoneal; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipases

2017
Hepatic toxicity following actinomycin D chemotherapy in treatment of familial gestational trophoblastic neoplasia: A case report.
    Medicine, 2018, Volume: 97, Issue:38

    Topics: Adaptor Proteins, Signal Transducing; Administration, Intravenous; Antibiotics, Antineoplastic; Asian People; Chemical and Drug Induced Liver Injury; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Trophoblastic Disease; Humans; Hypolipidemic Agents; Liver; Lung Neoplasms; Mutation; Neoplasm Staging; Phosphatidylcholines; Pregnancy; Proteins; Saponins; Tomography, X-Ray Computed; Treatment Outcome; Triterpenes; Young Adult

2018
Development of catechin-phospholipid complex to enhance the bioavailability and modulatory potential against cadmium-induced oxidative stress in rats liver.
    Archives of physiology and biochemistry, 2020, Volume: 126, Issue:1

    Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Cadmium Chloride; Catalase; Catechin; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Carriers; Gene Expression; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Phosphatidylcholines; Rats; Rats, Wistar; Superoxide Dismutase

2020
[The effect of phospholipid hepatoprotectors on lipid peroxidation in liver and content of cytokines in the blood in experimental pathology caused by isoniazid].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2012, Issue:6

    Topics: Alkaline Phosphatase; Animals; Antioxidants; Antitubercular Agents; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Interleukin-10; Isoniazid; Lipid Peroxidation; Male; Phosphatidylcholines; Phospholipids; Rats; Transaminases; Tumor Necrosis Factor-alpha

2012
Dietary phosphatidylinositol protects C57BL/6 mice from concanavalin A-induced liver injury by modulating immune cell functions.
    Molecular nutrition & food research, 2013, Volume: 57, Issue:9

    Topics: Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Diet; Liver; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Soybean Oil

2013
Effects of phospholipid hepatoprotectors on apoptosis during experimental liver pathology induced by isoniazid and paracetamol.
    Bulletin of experimental biology and medicine, 2013, Volume: 154, Issue:5

    Topics: Acetaminophen; Alkaline Phosphatase; Animals; Apoptosis; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Granulocytes; Interleukin-10; Isoniazid; Liver Function Tests; Lymphocytes; Male; Phosphatidylcholines; Phospholipids; Rats; Succinic Acid; Transaminases; Tumor Necrosis Factor-alpha

2013
UPLC-MS-based serum metabonomics for identifying acute liver injury biomarkers in Chinese miniature pigs.
    Toxicology letters, 2014, Mar-21, Volume: 225, Issue:3

    Topics: Animals; Bile Acids and Salts; Biomarkers; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Fatty Acids; Lysophosphatidylcholines; Male; Metabolomics; Multivariate Analysis; Phosphatidylcholines; Random Allocation; Spectrometry, Mass, Electrospray Ionization; Swine; Swine, Miniature; Tandem Mass Spectrometry

2014
Hepatoprotective effect of phosphatidylcholine against carbon tetrachloride liver damage in mice.
    Biochemical and biophysical research communications, 2015, May-01, Volume: 460, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Male; Mice; Mice, Inbred ICR; Phosphatidylcholines

2015
Carbon tetrachloride-induced hepatic and renal damages in rat: inhibitory effects of cacao polyphenol.
    Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:10

    Topics: Acute Kidney Injury; Animals; Antioxidants; Cacao; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Gene Expression; Glutathione; Glutathione Peroxidase; Injections, Intraperitoneal; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Phosphatidylcholines; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Inbred F344; RNA, Messenger

2015
Inhibition of MDR3 Activity in Human Hepatocytes by Drugs Associated with Liver Injury.
    Chemical research in toxicology, 2015, Oct-19, Volume: 28, Issue:10

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Deuterium; Hepatocytes; Humans; Itraconazole; Phosphatidylcholines; Tandem Mass Spectrometry; Taurocholic Acid; Verapamil

2015
[Pharmacoeconomic Analysis of the Use of Hepatoprotectors in Management of Drug-Associated Liver Injury Due to Hodgkin's Lymphoma Chemotherapy].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2015, Volume: 60, Issue:7-8

    Topics: Antineoplastic Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; Disease Management; Hodgkin Disease; Humans; Liver; Phosphatidylcholines; Protective Agents; Retrospective Studies; S-Adenosylmethionine; Succinates; Treatment Outcome

2015
Arachidonic acid-containing phosphatidylcholine characterized by consolidated plasma and liver lipidomics as an early onset marker for tamoxifen-induced hepatic phospholipidosis.
    Journal of applied toxicology : JAT, 2017, Volume: 37, Issue:8

    Topics: Animals; Arachidonic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Lipid Metabolism; Lipidoses; Liver; Male; Phosphatidylcholines; Rats, Sprague-Dawley; Tamoxifen

2017
The synthetic bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide suppresses TNFα-induced liver injury.
    Journal of hepatology, 2011, Volume: 54, Issue:4

    Topics: Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cytokines; Galactosamine; Gene Expression; Humans; Inflammation Mediators; Lipopolysaccharides; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phospholipases A2; Phospholipids; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid

2011
[The use of hepatic protectors in clinical practice].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:10 Pt 2

    Topics: Amino Acids; Chemical and Drug Induced Liver Injury; Cytoprotection; Drug Combinations; Flavonoids; Hepatocytes; Humans; Liver; Phosphatidylcholines; Protective Agents; Pyridoxine; Pyrrolidonecarboxylic Acid; Ursodeoxycholic Acid

2012
[Membrane-stabilizing effect of phospholipid liposomes in toxic hepatitis].
    Klinicheskaia laboratornaia diagnostika, 2002, Issue:6

    Topics: Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Glycyrrhizic Acid; Gossypium; Lipid Peroxidation; Liposomes; Liver; Male; Phosphatidylcholines; Rats; Unithiol

2002
[THE EFFECT OF ESSENTIAL PHOSPHOLIPIDS ON THE ETHIONINE DAMAGE OF THE RAT LIVER].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1963, Volume: 23

    Topics: Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Liver; Liver Diseases; Necrosis; Phosphatidylcholines; Phospholipids; Rats; Research; Toxicology

1963
[RELATIONS BETWEEN THE ANTINECROTIC AND HEPATOPROTECTIVE ACTION OF ESSENTIAL PHOSPHOLIPIDS AND ENZYMATIC ACTIVITY IN THE BLOOD OF RATS POISONED WITH CARBON TETRACHLORIDE].
    Rivista di patologia e clinica, 1964, Volume: 19

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Fatty Acids; Fatty Acids, Essential; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehydrogenase; Hepatitis; L-Lactate Dehydrogenase; Malate Dehydrogenase; Pharmacology; Phosphatidylcholines; Rats; Research; Toxicology

1964
Hepatoprotective effects of the water extract from adzuki bean hulls on acetaminophen-induced damage in rat liver.
    Journal of nutritional science and vitaminology, 2004, Volume: 50, Issue:5

    Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Fabaceae; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Liver Diseases; Male; Phosphatidylcholines; Phosphatidylethanolamines; Plant Extracts; Rats; Rats, Inbred F344; Water

2004
The hepatotoxicity of antifungal medications in bone marrow transplant recipients.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Aug-01, Volume: 41, Issue:3

    Topics: Adult; Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Case-Control Studies; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Drug Combinations; Female; Fluconazole; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phosphatidylcholines; Phosphatidylglycerols; Risk Factors

2005
Hepatotoxicity associated with antifungal therapy after bone marrow transplantation.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Aug-01, Volume: 41, Issue:3

    Topics: Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Drug Combinations; Fluconazole; Humans; Phosphatidylcholines; Phosphatidylglycerols; Risk Factors

2005
Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration.
    Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:9

    Topics: Absorption; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drug Carriers; Guinea Pigs; Intestinal Absorption; Jugular Veins; Lactoferrin; Liposomes; Lymph; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Phosphatidylcholines; Phytosterols; Rats; Rats, Wistar

2005
Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance.
    International journal of pharmaceutics, 2006, Aug-17, Volume: 319, Issue:1-2

    Topics: Administration, Buccal; Alanine Transaminase; Amines; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Cholesterol; Drug Stability; Drug Storage; Evaluation Studies as Topic; Liposomes; Liver; Liver Diseases; Oxidative Stress; Particle Size; Phosphatidylcholines; Polysorbates; Rats; Silymarin; Temperature

2006
Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats.
    International journal of pharmaceutics, 2007, Feb-07, Volume: 330, Issue:1-2

    Topics: Animals; Area Under Curve; Calorimetry, Differential Scanning; Carbon Tetrachloride Poisoning; Catalase; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Half-Life; Male; Phosphatidylcholines; Rats; Rats, Wistar; Solubility; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances

2007
A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis.
    Biochimica et biophysica acta, 2007, Volume: 1771, Issue:7

    Topics: Animals; Apolipoprotein A-I; Chemical and Drug Induced Liver Injury; Choline Deficiency; Female; Glyburide; Hepatocytes; Homeostasis; Lipoproteins, HDL; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Sex Characteristics

2007
Effects of liposomal amphotericin B versus an amphotericin B lipid complex on liver histopathology in patients with hematologic malignancies and invasive fungal infections: a retrospective, nonrandomized autopsy study.
    Clinical therapeutics, 2007, Volume: 29, Issue:9

    Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Autopsy; Chemical and Drug Induced Liver Injury; Drug Carriers; Drug Combinations; Female; Hematologic Neoplasms; Humans; Liposomes; Liver; Male; Middle Aged; Mycoses; Phosphatidylcholines; Phosphatidylglycerols; Retrospective Studies

2007
Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites.
    Seminars in liver disease, 1981, Volume: 1, Issue:2

    Topics: Acetaminophen; Alkylation; Animals; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ethane; Glutathione; Liver; Liver Diseases; Male; Mice; Pentanes; Peroxides; Pharmaceutical Preparations; Phosphatidylcholines

1981
An evaluation of the efficacy and safety of tetrahydroaminoacridine (THA) without lecithin in the treatment of Alzheimer's disease.
    Age and ageing, 1993, Volume: 22, Issue:5

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Function Tests; Male; Middle Aged; Neuropsychological Tests; Phosphatidylcholines; Quality of Life; Tacrine

1993
[Stimulation of regenerative processes and correction of the functional activity of the liver in its partial resection and toxic lesions].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 1996, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Glycine max; Helianthus; Hepatectomy; Hepatocyte Growth Factor; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Phosphatidylcholines; Prodigiozan; Rats; RNA

1996
Effects of crystalline nicotinic acid-induced hepatic dysfunction on serum low-density lipoprotein cholesterol and lecithin cholesteryl acyl transferase.
    The American journal of cardiology, 1998, Mar-15, Volume: 81, Issue:6

    Topics: Acyltransferases; Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Niacin; Phosphatidylcholines

1998
Ethanolamine stimulates repair processes in acute CCl4 damage of mouse liver.
    Toxicology letters, 1998, Jan-31, Volume: 94, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromodeoxyuridine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DNA; ErbB Receptors; Ethanolamine; Liver; Liver Regeneration; Male; Mice; Phosphatidylcholines; Phosphatidylethanolamines

1998
[Positive effects of essential phospholipids and improvement of life style in patients with toxic liver injury].
    Bratislavske lekarske listy, 1998, Volume: 99, Issue:2

    Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Male; Middle Aged; Occupational Diseases; Phosphatidylcholines; Temperance

1998
[Effects of hepatoprotective agents containing phospholipids on cytochrome P-450-dependent antitoxic liver function during experimental toxic hepatitis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:4

    Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Carotenoids; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Combinations; Inactivation, Metabolic; Liver; Male; Microsomes, Liver; Phosphatidylcholines; Phospholipids; Propanols; Rats; Silymarin

1999
Amphotericin B lipid complex for the treatment of patients with acute leukemia and hepatosplenic candidiasis.
    Leukemia research, 1999, Volume: 23, Issue:11

    Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Candidiasis; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Leukemia, Myeloid; Liver Diseases; Male; Middle Aged; Phosphatidylcholines; Phosphatidylglycerols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Splenic Diseases

1999
[Effect of the transcranial electrical stimulation of the endorphinergic brain structures on the functional activity of hepatocytes after toxic exposure].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2000, Volume: 86, Issue:11

    Topics: Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Electric Stimulation; Endorphins; Ethylene Dichlorides; Fatty Liver; Hepatocytes; Liver Function Tests; Male; Naloxone; Narcotic Antagonists; Phosphatidylcholines; Protective Agents; Rats; Rats, Wistar

2000
Lipoprotein abnormalities in galactosamine hepatitis: a model of experimental lecithin:cholesterol acyltransferase deficiency.
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1978, Volume: 150

    Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Cholesterol Esters; Disease Models, Animal; Female; Galactosamine; Hypolipoproteinemias; Lecithin Cholesterol Acyltransferase Deficiency; Lipids; Lipoproteins; Lysophosphatidylcholines; Phosphatidylcholines; Phospholipids; Rats

1978
Influence of phospholipids on liver damage. II. Changes in lipid content and synthesis after liver damage with carbontetrachloride and other agents.
    Acta hepato-gastroenterologica, 1975, Volume: 22, Issue:4

    Topics: Acetates; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA; Fatty Liver; Hepatectomy; Lipids; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Orotic Acid; Phosphatidylcholines; Phospholipids; Rats; Thymus Gland; X-Rays

1975
Influence of phospholids on liver damage. I. Carbontetrachloride poisoning and alterations in amino acid uptake, peroxidation, sialic acid content, and lysosomal enzymes.
    Acta hepato-gastroenterologica, 1975, Volume: 22, Issue:3

    Topics: Aminoisobutyric Acids; Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Glucuronidase; Liver; Lysosomes; Male; Mice; Mice, Inbred BALB C; Peroxides; Phosphatidylcholines; Rats; Sialic Acids

1975
[The effect of silybin-dihemisuccinate on regulation disorders in phospholipid metabolism in acute galactosamine intoxication in the rat].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Animals; Chemical and Drug Induced Liver Injury; Flavonoids; Galactosamine; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Palmitic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Silymarin; Triglycerides

1975
Influence of d-galactosamine hydrochloride on lipids and their fatty acid composition in plasma and liver of guinea pigs.
    Acta hepato-gastroenterologica, 1976, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Fatty Acids; Galactosamine; Linoleic Acids; Linolenic Acids; Lipid Metabolism; Liver; Male; Microsomes, Liver; Oleic Acids; Palmitic Acids; Phosphatidylcholines; Phospholipids; Rats

1976
Protective activity of silipide on liver damage in rodents.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:4

    Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethanol; Female; Galactosamine; Male; Phosphatidylcholines; Praseodymium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Silymarin

1992
Disturbances in oxidative phosphorylation in the liver of rats with heliotrine-induced hepatitis and restoration by phosphatidylcholine and ATP.
    Biomedical science, 1991, Volume: 2, Issue:5

    Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Drug Synergism; Electron Transport Complex IV; Male; Mitochondria, Liver; Oxidative Phosphorylation; Phosphatidylcholines; Pyrrolizidine Alkaloids; Rats

1991
Hepatic uptake and antihepatotoxic properties of vitamin E and liposomes in the mouse.
    Chemico-biological interactions, 1990, Volume: 75, Issue:1

    Topics: Acetaminophen; Animals; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Drug Carriers; Galactosamine; Lipopolysaccharides; Liposomes; Liver; Male; Mice; Phosphatidylcholines; Vitamin E

1990
[Effect of essential phospholipids (EPL) on the course of chronic poisoning with organic solvents in rats].
    Medycyna pracy, 1989, Volume: 40, Issue:4

    Topics: Animals; Antidotes; Chemical and Drug Induced Liver Injury; Chronic Disease; Drug Evaluation, Preclinical; Hydrocarbons; Liver; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Solvents

1989
[Effectiveness of hepatoprotective agents in experimental allyl alcohol poisoning].
    Gigiena truda i professional'nye zabolevaniia, 1989, Issue:5

    Topics: 1-Propanol; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Flavonoids; Liver; Male; Phosphatidylcholines; Phospholipids; Propanols; Rats; Rats, Inbred Strains; Silymarin

1989
[Phosphatidylcholine-induced repair of damaged hepatocyte membranes in heliotrine poisoning].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:4

    Topics: Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Activation; Fructose-Bisphosphate Aldolase; Glucose-6-Phosphatase; Liposomes; Male; Microsomes, Liver; Phosphatidylcholines; Pyrrolizidine Alkaloids; Rats

1987
[The effect of hepatoprotectors on lipid metabolism in CCl4-hepatitis].
    Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Flavonoids; Lipid Metabolism; Lipids; Liver; Male; Phosphatidylcholines; Phospholipids; Rats; Silymarin

1987
[Action of hepatoprotective agents in a tetracycline lesion of the liver].
    Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:4

    Topics: Animals; Bile; Catechin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Liver; Male; Phosphatidylcholines; Plant Extracts; Rats; Rats, Inbred Strains; Silymarin; Tetracycline

1987
["Essential" phospholipids in liver diseases].
    Fortschritte der Medizin, 1986, Apr-10, Volume: 104, Issue:14

    Topics: Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Liver Diseases, Alcoholic; Liver Function Tests; Phosphatidylcholines

1986
[Use of polyunsaturated phosphatidylcholine associated with a vitamin B complex in the treatment of hepatic injuries caused by antitubercular agents].
    La Clinica terapeutica, 1986, Sep-30, Volume: 118, Issue:6

    Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Liver Diseases; Phosphatidylcholines; Vitamin B Complex

1986
[Effectiveness of legalon and essentiale in a tetracycline-induced liver lesion].
    Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1986, Volume: 31, Issue:10

    Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flavonoids; Liver Diseases; Male; Phosphatidylcholines; Plants, Medicinal; Rats; Silymarin; Tetracycline

1986
Proceedings: Subcellular distribution of phospholipids in rare-earth induced liver damage.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Animals; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Fatty Liver; Female; Lipoproteins; Liver; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Praseodymium; Rats; Surface-Active Agents; Time Factors; Triglycerides

1974
Phospholipid changes during hepatic injury caused by carbon tetrachloride.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Chromatography, Ion Exchange; Fats, Unsaturated; Fatty Acids; Fatty Liver; Glycerol; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingomyelins

1967
[The incorporation of essential phospholipids into the organs of intact and galactosamine intoxicated rats].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:8

    Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Cardiolipins; Chemical and Drug Induced Liver Injury; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids, Essential; Galactosamine; Hydrolysis; Injections, Intravenous; Isotope Labeling; Liver; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Phospholipids; Rats; Tritium

1974
[Relationship between lecithin-lysolecithin and cholesterol-cholesterol esters in the serum of the rat with galactosamine-induced hepatosis].
    Experientia, 1972, Nov-15, Volume: 28, Issue:11

    Topics: Acute Disease; Acyltransferases; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Esters; Galactosamine; Injections, Intraperitoneal; Liver; Liver Diseases; Lysophosphatidylcholines; Male; Phosphatidylcholines; Rats; Time Factors

1972
[Lipid metabolism disorders in the rat following parenteral deoxycholate in toxication. Brief report].
    Arzneimittel-Forschung, 1973, Volume: 23

    Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Injections, Intravenous; Lipid Metabolism; Liver; Liver Regeneration; Lysophosphatidylcholines; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Time Factors

1973
[Cholesterol metabolism and plasma lecithin-cholesterol acyl transferase in experimental hepatitis and cholestasis in the rat].
    Zeitschrift fur klinische Chemie und klinische Biochemie, 1970, Volume: 8, Issue:4

    Topics: Acyltransferases; Animals; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Cholestasis; Cholesterol; Chromatography, Thin Layer; Esters; Hepatitis; Hexosamines; Male; Phosphatidylcholines; Rats; Thiocyanates

1970
Studies on the pharmacological control of hyperlipemia in experimental nephrotic syndrome.
    Biochemical pharmacology, 1970, Volume: 19, Issue:10

    Topics: Animals; Butyrates; Chemical and Drug Induced Liver Injury; Cholesterol; Cholestyramine Resin; Disease Models, Animal; Female; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Liver; Nephrotic Syndrome; Nucleosides; Organ Size; Phosphatidylcholines; Phospholipids; Propionates; Puromycin; Rats; Thyroxine; Triglycerides

1970
Effect of carbon tetrachloride administration on the synthesis of triglycerides and phospholipids in rat liver.
    Journal of lipid research, 1969, Volume: 10, Issue:5

    Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Coenzyme A; Depression, Chemical; Female; In Vitro Techniques; Lipids; Liver; Male; Methionine; Microsomes; Mitochondria, Liver; Nucleotides; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Rats; Triglycerides

1969