phosphatidylcholines has been researched along with Chemical and Drug Induced Liver Injury in 71 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 27 (38.03) | 18.7374 |
1990's | 12 (16.90) | 18.2507 |
2000's | 11 (15.49) | 29.6817 |
2010's | 17 (23.94) | 24.3611 |
2020's | 4 (5.63) | 2.80 |
Authors | Studies |
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Liu, Q; Liu, R; Lu, L; Pu, Y; Wang, S; Yin, L; Zhang, H; Zhang, Y; Zhao, C; Zhou, Q | 1 |
Bednarz, H; Ernst, R; Fatangare, A; Giampà, M; Kampa, JM; Niehaus, K; Riefke, B; Sahin, M; Slopianka, M | 1 |
Han, X; Lei, X; Li, J; Liu, L; Mao, Y; Qian, Y; Tang, J; Wang, Y; Xu, Q; Zeng, M; Zhang, J; Zhong, W | 1 |
Du, S; Jin, S; Liu, M; Yan, H | 1 |
Li, CM; Li, XB; Liu, XL; Ma, SC; Mao, YM; Ming, YN; Wang, XL; Wang, ZY; Zhang, JY | 1 |
Chenggang, Z; Dongchen, L; Jianjun, L; Liansheng, W; Naiqiong, W; Qian, D; Yanjun, Z; Ying, G; Yuanlin, G; Zhanying, H | 1 |
Li, Q; Ma, Y; Mu, X; Song, L; Wang, D; Yin, R; Zhao, X | 1 |
Athmouni, K; Ayadi, H; El Feki, A; Mkadmini Hammi, K | 1 |
Burkova, VN; Korshunov, DA; Udut, VV; Vaizova, OE; Vengerovskiĭ, AI | 1 |
Inafuku, A; Inafuku, M; Nagao, K; Oku, H; Taira, N; Toda, T; Yanagita, T | 1 |
Dygai, AM; Udut, VV; Vengerovsky, AI | 1 |
Adewoles, IF; Irabor, AE; Kuti, MA; Ogunbode, O; Otegbayo, JA | 1 |
Cherenkov, VG; Petrov, AB; Strozhenkov, MM; Vasil'eva, TM | 1 |
Cao, H; Chen, D; Lu, J; Ma, J; Su, X; Sun, H; Wang, Y; Yang, X; Yu, J; Zhu, C | 1 |
Kim, S; Kwon, J; Na, JY; Song, K | 1 |
Kamei, M; Kimura, F; Miyazawa, T; Nakagawa, K; Suzuki, K; Yamamoto, T | 1 |
Cai, L; He, K; Liu, H; Shi, Q; Woolf, TF | 1 |
Dvornichenko, VV; Morikov, DD; Morikova, EG | 1 |
Goda, K; Kobayashi, A; Maekawa, K; Saito, K; Saito, Y; Sugai, S; Yamada, N | 1 |
Chamulitrat, W; Pathil, A; Stremmel, W; Warth, A | 1 |
Bukshuk, AA; Maslovskiĭ, LV; Minushkin, ON | 1 |
Akhundzhanova, LL; Aripov, OA; Khalimbetov, GS | 1 |
PETZOLD, H; ROSAM, E | 1 |
DELUTTEROTTI, A; SARTORI, S; VALAGUSSA, L | 1 |
Estany, C; Gómez, L; Martí, JM; Martino, R; Sierra, J; Subirà, M | 1 |
Chiji, H; Fukushima, M; Han, KH; Lee, CH; Nakano, M; Ohba, K; Sekikawa, M; Shimada, K | 1 |
Avorn, J; Fischer, MA; Rubin, RH; Winkelmayer, WC | 1 |
Leather, H; Wingard, JR | 1 |
Harada, E; Imanaka, H; Ishikado, A; Makino, T; Takeuchi, T | 1 |
Afifi, NN; El-Samaligy, MS; Mahmoud, EA | 1 |
Gantait, A; Maiti, K; Mukherjee, K; Mukherjee, PK; Saha, BP | 1 |
Agellon, LB; Li, Z; Vance, DE | 1 |
Chamilos, G; Chemaly, R; Kontoyiannis, DP; Lewis, RE; Luna, M; Raad, II | 1 |
Horning, MG; Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV | 1 |
Boyle, M; Mulligan, K; Neubauer, KA; O'Neill, D; Royston, VH; Scott, M; Surmon, DJ; Wilcock, GK | 1 |
Gauthier, L; Gauthier, S | 1 |
Abakumova, OIu; Fedorova, LM; Gavril'chak, AV; Karagiulian, SR; Kliashchitskiĭ, BA; Kovaleva, GG; Kutsenko, NG; Li, VS; Mitina, VKh; Podobed, OV; Popov, AA; Shekhter, AB | 1 |
Grundy, SM; Tatò, F; Vega, GL | 1 |
Hirano, K; Murakami, T; Nagamura, Y | 1 |
Glasa, J; Hlavatý, I; Holomán, J; Lukácsová, M; Prachar, V; Veningerová, M | 1 |
Saratikov, AS; Vengerovskiĭ, AI | 1 |
Philips, DL; Sallah, S; Sallah, W; Semelka, RC; Vainright, JR | 1 |
Kolbasov, SE; Lebedev, VP; Melikhova, MV; Stroĭkova, GV; Zamuruev, ON | 1 |
Bonorris, GG; Marks, JW; Pearlman, BJ; Schoenfield, LJ | 1 |
Kuiken, LB; Ragland, JB; Sabesin, SM | 1 |
Goldstein, LI; Schoenfield, LJ | 1 |
Bartsch, GG; Gerber, GB | 1 |
Bartsch, GG; Deroo, J; Gerber, GB | 1 |
Lohmann, J; Rauen, HM; Schriewer, H | 1 |
Bartsch, GG; Brachtel, D; Gallenkamp, H; Löhr, JP; Richter, E | 1 |
Conti, M; Magistretti, MJ; Malandrino, S | 1 |
Aripov, AN; Atabekov, AG; Dombrovskaya, NV; Fesenko, LM; Gagel'gans, AI; Gizatullina, ZZ; Mokhova, EN | 1 |
Chatellier, G; Lacomblez, L | 1 |
Wendel, A; Werner, C | 1 |
Put, A; Samochowiec, L; Wójcicki, J; Wyczarska-Szok, K | 1 |
Saratikov, AS; Sedykh, IM; Vengerovskiĭ, AI | 1 |
Archakov, AI; Dobrynina, OV; Shatinina, SZ | 1 |
Chuchalin, VS; Paul's, OV; Saratikov, AS; Vengerovskiĭ, AI | 1 |
Drogovoz, SM; Porokhniak, LA; Rogozhin, BA | 1 |
Maiwald, L | 1 |
Costanzo, V; Granata, M; Lazzara, A; Maucceri, G | 1 |
Skakun, NP; Stepanova, NIu | 1 |
Campbell, TC; Hayes, JR | 1 |
Oberdisse, E; von Lehmann, V | 1 |
Sgoutas, DS | 1 |
Betzing, H; Lekim, D | 1 |
Rauen, HM; Schriewer, H | 2 |
Kattermann, R; Wolfrum, DI | 1 |
Edwards, KD; Galli, C; Paoletti, R; Usardi, MM | 1 |
Shimizu, Y | 1 |
4 review(s) available for phosphatidylcholines and Chemical and Drug Induced Liver Injury
Article | Year |
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What have we learned from the THA trials to facilitate testing of new AChE inhibitors.
Topics: Alzheimer Disease; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Diseases; Humans; Phosphatidylcholines; Psychological Tests; Research Design; Tacrine; Treatment Outcome | 1993 |
Gallstone dissolution--a progress report.
Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Contraceptives, Oral, Synthetic; Deoxycholic Acid; Diarrhea; Enterohepatic Circulation; Estrogens; Female; Gallstones; Humans; Liver; Male; Phosphatidylcholines; Pregnancy; Recurrence; Risk | 1979 |
Gallstones: pathogenesis and medical treatment.
Topics: Adult; Animals; Arizona; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Fasting; Female; Guinea Pigs; Humans; Indians, North American; Liver; Male; Middle Aged; Minnesota; Phosphatidylcholines | 1975 |
Role of nutrition in the drug-metabolizing enzyme system.
Topics: Ascorbic Acid Deficiency; Calcium; Carbohydrates; Carcinogens; Catalysis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dietary Proteins; Fatty Acids; Humans; Iron Deficiencies; Kinetics; Lipids; Lipotropic Agents; Liver; Magnesium Deficiency; Mixed Function Oxygenases; Mutagens; Nicotinic Acids; Nutritional Physiological Phenomena; Oxidoreductases; Pharmaceutical Preparations; Phenobarbital; Phosphatidylcholines; Protein Deficiency; Riboflavin Deficiency; Thiamine Deficiency; Trace Elements; Vitamin A Deficiency | 1974 |
5 trial(s) available for phosphatidylcholines and Chemical and Drug Induced Liver Injury
Article | Year |
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A Multicenter and Randomized Controlled Trial of Bicyclol in the Treatment of Statin-Induced Liver Injury.
Topics: Adult; Aged; Alanine Transaminase; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Middle Aged; Phosphatidylcholines | 2017 |
Livolin ameliorates elevations in alanine transaminase in HIV infected patients commencing highly active antiretroviral therapy.
Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Phosphatidylcholines; Treatment Outcome; Vitamin B Complex; Vitamin E; Young Adult | 2012 |
[Possibilities of remaxol in prevention of toxic hepatitis during chemotherapy for cancer patients].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neoplasms; Patient Selection; Phosphatidylcholines; Protective Agents; Succinates; Treatment Outcome | 2013 |
Low-dose amphotericin B lipid complex vs. conventional amphotericin B for empirical antifungal therapy of neutropenic fever in patients with hematologic malignancies--a randomized, controlled trial.
Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Drug Combinations; Female; Fever of Unknown Origin; Hematologic Neoplasms; Humans; Hypokalemia; Immunocompromised Host; Incidence; Kidney Diseases; Male; Middle Aged; Mycoses; Neutropenia; Peripheral Blood Stem Cell Transplantation; Phosphatidylcholines; Phosphatidylglycerols; Treatment Outcome | 2004 |
Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Français d'Etude de la Tetrahydroaminoacridine.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aminoacridines; Behavior; Chemical and Drug Induced Liver Injury; Cognition; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multicenter Studies as Topic; Phosphatidylcholines; Psychological Tests; Randomized Controlled Trials as Topic; Tacrine | 1990 |
62 other study(ies) available for phosphatidylcholines and Chemical and Drug Induced Liver Injury
Article | Year |
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Lipid metabolism disorders contribute to hepatotoxicity of ICR mice induced by nitrosamines exposure.
Topics: Animals; Chemical and Drug Induced Liver Injury; Fatty Acids; Lipid Metabolism; Lipid Metabolism Disorders; Liver; Mice; Mice, Inbred ICR; Nitrosamines; Phosphatidylcholines; Phosphatidylethanolamines | 2022 |
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model.
Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Lipid Metabolism; Liver; Male; Mass Spectrometry; Organ Size; Phosphatidylcholines; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation | 2020 |
Exploring the efficacy and safety of polyene phosphatidylcholine for treatment of drug-induced liver injury using the Roussel Uclaf causality assessment method: a propensity score matching comparison.
Topics: Chemical and Drug Induced Liver Injury; Humans; Phosphatidylcholines; Propensity Score; Retrospective Studies | 2021 |
Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine.
Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Liberation; Kidney; Liposomes; Liver; Male; Matrines; Mice; Myocardium; Phosphatidylcholines; Protective Agents; Quinolizines; Spleen; Tissue Distribution | 2017 |
Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Choline Kinase; Chromatography, Liquid; Gene Expression Regulation; Hepatocytes; Injections, Intraperitoneal; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipases | 2017 |
Hepatic toxicity following actinomycin D chemotherapy in treatment of familial gestational trophoblastic neoplasia: A case report.
Topics: Adaptor Proteins, Signal Transducing; Administration, Intravenous; Antibiotics, Antineoplastic; Asian People; Chemical and Drug Induced Liver Injury; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Trophoblastic Disease; Humans; Hypolipidemic Agents; Liver; Lung Neoplasms; Mutation; Neoplasm Staging; Phosphatidylcholines; Pregnancy; Proteins; Saponins; Tomography, X-Ray Computed; Treatment Outcome; Triterpenes; Young Adult | 2018 |
Development of catechin-phospholipid complex to enhance the bioavailability and modulatory potential against cadmium-induced oxidative stress in rats liver.
Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Cadmium Chloride; Catalase; Catechin; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Carriers; Gene Expression; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Phosphatidylcholines; Rats; Rats, Wistar; Superoxide Dismutase | 2020 |
[The effect of phospholipid hepatoprotectors on lipid peroxidation in liver and content of cytokines in the blood in experimental pathology caused by isoniazid].
Topics: Alkaline Phosphatase; Animals; Antioxidants; Antitubercular Agents; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Interleukin-10; Isoniazid; Lipid Peroxidation; Male; Phosphatidylcholines; Phospholipids; Rats; Transaminases; Tumor Necrosis Factor-alpha | 2012 |
Dietary phosphatidylinositol protects C57BL/6 mice from concanavalin A-induced liver injury by modulating immune cell functions.
Topics: Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Diet; Liver; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Soybean Oil | 2013 |
Effects of phospholipid hepatoprotectors on apoptosis during experimental liver pathology induced by isoniazid and paracetamol.
Topics: Acetaminophen; Alkaline Phosphatase; Animals; Apoptosis; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Granulocytes; Interleukin-10; Isoniazid; Liver Function Tests; Lymphocytes; Male; Phosphatidylcholines; Phospholipids; Rats; Succinic Acid; Transaminases; Tumor Necrosis Factor-alpha | 2013 |
UPLC-MS-based serum metabonomics for identifying acute liver injury biomarkers in Chinese miniature pigs.
Topics: Animals; Bile Acids and Salts; Biomarkers; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Fatty Acids; Lysophosphatidylcholines; Male; Metabolomics; Multivariate Analysis; Phosphatidylcholines; Random Allocation; Spectrometry, Mass, Electrospray Ionization; Swine; Swine, Miniature; Tandem Mass Spectrometry | 2014 |
Hepatoprotective effect of phosphatidylcholine against carbon tetrachloride liver damage in mice.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Male; Mice; Mice, Inbred ICR; Phosphatidylcholines | 2015 |
Carbon tetrachloride-induced hepatic and renal damages in rat: inhibitory effects of cacao polyphenol.
Topics: Acute Kidney Injury; Animals; Antioxidants; Cacao; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Gene Expression; Glutathione; Glutathione Peroxidase; Injections, Intraperitoneal; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Phosphatidylcholines; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Inbred F344; RNA, Messenger | 2015 |
Inhibition of MDR3 Activity in Human Hepatocytes by Drugs Associated with Liver Injury.
Topics: ATP Binding Cassette Transporter, Subfamily B; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Deuterium; Hepatocytes; Humans; Itraconazole; Phosphatidylcholines; Tandem Mass Spectrometry; Taurocholic Acid; Verapamil | 2015 |
[Pharmacoeconomic Analysis of the Use of Hepatoprotectors in Management of Drug-Associated Liver Injury Due to Hodgkin's Lymphoma Chemotherapy].
Topics: Antineoplastic Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; Disease Management; Hodgkin Disease; Humans; Liver; Phosphatidylcholines; Protective Agents; Retrospective Studies; S-Adenosylmethionine; Succinates; Treatment Outcome | 2015 |
Arachidonic acid-containing phosphatidylcholine characterized by consolidated plasma and liver lipidomics as an early onset marker for tamoxifen-induced hepatic phospholipidosis.
Topics: Animals; Arachidonic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Lipid Metabolism; Lipidoses; Liver; Male; Phosphatidylcholines; Rats, Sprague-Dawley; Tamoxifen | 2017 |
The synthetic bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide suppresses TNFα-induced liver injury.
Topics: Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cytokines; Galactosamine; Gene Expression; Humans; Inflammation Mediators; Lipopolysaccharides; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phospholipases A2; Phospholipids; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid | 2011 |
[The use of hepatic protectors in clinical practice].
Topics: Amino Acids; Chemical and Drug Induced Liver Injury; Cytoprotection; Drug Combinations; Flavonoids; Hepatocytes; Humans; Liver; Phosphatidylcholines; Protective Agents; Pyridoxine; Pyrrolidonecarboxylic Acid; Ursodeoxycholic Acid | 2012 |
[Membrane-stabilizing effect of phospholipid liposomes in toxic hepatitis].
Topics: Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Glycyrrhizic Acid; Gossypium; Lipid Peroxidation; Liposomes; Liver; Male; Phosphatidylcholines; Rats; Unithiol | 2002 |
[THE EFFECT OF ESSENTIAL PHOSPHOLIPIDS ON THE ETHIONINE DAMAGE OF THE RAT LIVER].
Topics: Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Liver; Liver Diseases; Necrosis; Phosphatidylcholines; Phospholipids; Rats; Research; Toxicology | 1963 |
[RELATIONS BETWEEN THE ANTINECROTIC AND HEPATOPROTECTIVE ACTION OF ESSENTIAL PHOSPHOLIPIDS AND ENZYMATIC ACTIVITY IN THE BLOOD OF RATS POISONED WITH CARBON TETRACHLORIDE].
Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Fatty Acids; Fatty Acids, Essential; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehydrogenase; Hepatitis; L-Lactate Dehydrogenase; Malate Dehydrogenase; Pharmacology; Phosphatidylcholines; Rats; Research; Toxicology | 1964 |
Hepatoprotective effects of the water extract from adzuki bean hulls on acetaminophen-induced damage in rat liver.
Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Fabaceae; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Liver Diseases; Male; Phosphatidylcholines; Phosphatidylethanolamines; Plant Extracts; Rats; Rats, Inbred F344; Water | 2004 |
The hepatotoxicity of antifungal medications in bone marrow transplant recipients.
Topics: Adult; Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Case-Control Studies; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Drug Combinations; Female; Fluconazole; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phosphatidylcholines; Phosphatidylglycerols; Risk Factors | 2005 |
Hepatotoxicity associated with antifungal therapy after bone marrow transplantation.
Topics: Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Drug Combinations; Fluconazole; Humans; Phosphatidylcholines; Phosphatidylglycerols; Risk Factors | 2005 |
Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration.
Topics: Absorption; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drug Carriers; Guinea Pigs; Intestinal Absorption; Jugular Veins; Lactoferrin; Liposomes; Lymph; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Phosphatidylcholines; Phytosterols; Rats; Rats, Wistar | 2005 |
Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance.
Topics: Administration, Buccal; Alanine Transaminase; Amines; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Cholesterol; Drug Stability; Drug Storage; Evaluation Studies as Topic; Liposomes; Liver; Liver Diseases; Oxidative Stress; Particle Size; Phosphatidylcholines; Polysorbates; Rats; Silymarin; Temperature | 2006 |
Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats.
Topics: Animals; Area Under Curve; Calorimetry, Differential Scanning; Carbon Tetrachloride Poisoning; Catalase; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Half-Life; Male; Phosphatidylcholines; Rats; Rats, Wistar; Solubility; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2007 |
A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis.
Topics: Animals; Apolipoprotein A-I; Chemical and Drug Induced Liver Injury; Choline Deficiency; Female; Glyburide; Hepatocytes; Homeostasis; Lipoproteins, HDL; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Sex Characteristics | 2007 |
Effects of liposomal amphotericin B versus an amphotericin B lipid complex on liver histopathology in patients with hematologic malignancies and invasive fungal infections: a retrospective, nonrandomized autopsy study.
Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Autopsy; Chemical and Drug Induced Liver Injury; Drug Carriers; Drug Combinations; Female; Hematologic Neoplasms; Humans; Liposomes; Liver; Male; Middle Aged; Mycoses; Phosphatidylcholines; Phosphatidylglycerols; Retrospective Studies | 2007 |
Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites.
Topics: Acetaminophen; Alkylation; Animals; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ethane; Glutathione; Liver; Liver Diseases; Male; Mice; Pentanes; Peroxides; Pharmaceutical Preparations; Phosphatidylcholines | 1981 |
An evaluation of the efficacy and safety of tetrahydroaminoacridine (THA) without lecithin in the treatment of Alzheimer's disease.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Function Tests; Male; Middle Aged; Neuropsychological Tests; Phosphatidylcholines; Quality of Life; Tacrine | 1993 |
[Stimulation of regenerative processes and correction of the functional activity of the liver in its partial resection and toxic lesions].
Topics: Animals; Anti-Bacterial Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Glycine max; Helianthus; Hepatectomy; Hepatocyte Growth Factor; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Phosphatidylcholines; Prodigiozan; Rats; RNA | 1996 |
Effects of crystalline nicotinic acid-induced hepatic dysfunction on serum low-density lipoprotein cholesterol and lecithin cholesteryl acyl transferase.
Topics: Acyltransferases; Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Niacin; Phosphatidylcholines | 1998 |
Ethanolamine stimulates repair processes in acute CCl4 damage of mouse liver.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromodeoxyuridine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DNA; ErbB Receptors; Ethanolamine; Liver; Liver Regeneration; Male; Mice; Phosphatidylcholines; Phosphatidylethanolamines | 1998 |
[Positive effects of essential phospholipids and improvement of life style in patients with toxic liver injury].
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Male; Middle Aged; Occupational Diseases; Phosphatidylcholines; Temperance | 1998 |
[Effects of hepatoprotective agents containing phospholipids on cytochrome P-450-dependent antitoxic liver function during experimental toxic hepatitis].
Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Carotenoids; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Combinations; Inactivation, Metabolic; Liver; Male; Microsomes, Liver; Phosphatidylcholines; Phospholipids; Propanols; Rats; Silymarin | 1999 |
Amphotericin B lipid complex for the treatment of patients with acute leukemia and hepatosplenic candidiasis.
Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Candidiasis; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Leukemia, Myeloid; Liver Diseases; Male; Middle Aged; Phosphatidylcholines; Phosphatidylglycerols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Splenic Diseases | 1999 |
[Effect of the transcranial electrical stimulation of the endorphinergic brain structures on the functional activity of hepatocytes after toxic exposure].
Topics: Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Electric Stimulation; Endorphins; Ethylene Dichlorides; Fatty Liver; Hepatocytes; Liver Function Tests; Male; Naloxone; Narcotic Antagonists; Phosphatidylcholines; Protective Agents; Rats; Rats, Wistar | 2000 |
Lipoprotein abnormalities in galactosamine hepatitis: a model of experimental lecithin:cholesterol acyltransferase deficiency.
Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Cholesterol Esters; Disease Models, Animal; Female; Galactosamine; Hypolipoproteinemias; Lecithin Cholesterol Acyltransferase Deficiency; Lipids; Lipoproteins; Lysophosphatidylcholines; Phosphatidylcholines; Phospholipids; Rats | 1978 |
Influence of phospholipids on liver damage. II. Changes in lipid content and synthesis after liver damage with carbontetrachloride and other agents.
Topics: Acetates; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA; Fatty Liver; Hepatectomy; Lipids; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Orotic Acid; Phosphatidylcholines; Phospholipids; Rats; Thymus Gland; X-Rays | 1975 |
Influence of phospholids on liver damage. I. Carbontetrachloride poisoning and alterations in amino acid uptake, peroxidation, sialic acid content, and lysosomal enzymes.
Topics: Aminoisobutyric Acids; Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Glucuronidase; Liver; Lysosomes; Male; Mice; Mice, Inbred BALB C; Peroxides; Phosphatidylcholines; Rats; Sialic Acids | 1975 |
[The effect of silybin-dihemisuccinate on regulation disorders in phospholipid metabolism in acute galactosamine intoxication in the rat].
Topics: Animals; Chemical and Drug Induced Liver Injury; Flavonoids; Galactosamine; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Palmitic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Silymarin; Triglycerides | 1975 |
Influence of d-galactosamine hydrochloride on lipids and their fatty acid composition in plasma and liver of guinea pigs.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Fatty Acids; Galactosamine; Linoleic Acids; Linolenic Acids; Lipid Metabolism; Liver; Male; Microsomes, Liver; Oleic Acids; Palmitic Acids; Phosphatidylcholines; Phospholipids; Rats | 1976 |
Protective activity of silipide on liver damage in rodents.
Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethanol; Female; Galactosamine; Male; Phosphatidylcholines; Praseodymium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Silymarin | 1992 |
Disturbances in oxidative phosphorylation in the liver of rats with heliotrine-induced hepatitis and restoration by phosphatidylcholine and ATP.
Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Drug Synergism; Electron Transport Complex IV; Male; Mitochondria, Liver; Oxidative Phosphorylation; Phosphatidylcholines; Pyrrolizidine Alkaloids; Rats | 1991 |
Hepatic uptake and antihepatotoxic properties of vitamin E and liposomes in the mouse.
Topics: Acetaminophen; Animals; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Drug Carriers; Galactosamine; Lipopolysaccharides; Liposomes; Liver; Male; Mice; Phosphatidylcholines; Vitamin E | 1990 |
[Effect of essential phospholipids (EPL) on the course of chronic poisoning with organic solvents in rats].
Topics: Animals; Antidotes; Chemical and Drug Induced Liver Injury; Chronic Disease; Drug Evaluation, Preclinical; Hydrocarbons; Liver; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Solvents | 1989 |
[Effectiveness of hepatoprotective agents in experimental allyl alcohol poisoning].
Topics: 1-Propanol; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Flavonoids; Liver; Male; Phosphatidylcholines; Phospholipids; Propanols; Rats; Rats, Inbred Strains; Silymarin | 1989 |
[Phosphatidylcholine-induced repair of damaged hepatocyte membranes in heliotrine poisoning].
Topics: Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Activation; Fructose-Bisphosphate Aldolase; Glucose-6-Phosphatase; Liposomes; Male; Microsomes, Liver; Phosphatidylcholines; Pyrrolizidine Alkaloids; Rats | 1987 |
[The effect of hepatoprotectors on lipid metabolism in CCl4-hepatitis].
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Flavonoids; Lipid Metabolism; Lipids; Liver; Male; Phosphatidylcholines; Phospholipids; Rats; Silymarin | 1987 |
[Action of hepatoprotective agents in a tetracycline lesion of the liver].
Topics: Animals; Bile; Catechin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Liver; Male; Phosphatidylcholines; Plant Extracts; Rats; Rats, Inbred Strains; Silymarin; Tetracycline | 1987 |
["Essential" phospholipids in liver diseases].
Topics: Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Liver Diseases, Alcoholic; Liver Function Tests; Phosphatidylcholines | 1986 |
[Use of polyunsaturated phosphatidylcholine associated with a vitamin B complex in the treatment of hepatic injuries caused by antitubercular agents].
Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Liver Diseases; Phosphatidylcholines; Vitamin B Complex | 1986 |
[Effectiveness of legalon and essentiale in a tetracycline-induced liver lesion].
Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flavonoids; Liver Diseases; Male; Phosphatidylcholines; Plants, Medicinal; Rats; Silymarin; Tetracycline | 1986 |
Proceedings: Subcellular distribution of phospholipids in rare-earth induced liver damage.
Topics: Animals; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Fatty Liver; Female; Lipoproteins; Liver; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Praseodymium; Rats; Surface-Active Agents; Time Factors; Triglycerides | 1974 |
Phospholipid changes during hepatic injury caused by carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Chromatography, Ion Exchange; Fats, Unsaturated; Fatty Acids; Fatty Liver; Glycerol; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingomyelins | 1967 |
[The incorporation of essential phospholipids into the organs of intact and galactosamine intoxicated rats].
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Cardiolipins; Chemical and Drug Induced Liver Injury; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids, Essential; Galactosamine; Hydrolysis; Injections, Intravenous; Isotope Labeling; Liver; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Phospholipids; Rats; Tritium | 1974 |
[Relationship between lecithin-lysolecithin and cholesterol-cholesterol esters in the serum of the rat with galactosamine-induced hepatosis].
Topics: Acute Disease; Acyltransferases; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Esters; Galactosamine; Injections, Intraperitoneal; Liver; Liver Diseases; Lysophosphatidylcholines; Male; Phosphatidylcholines; Rats; Time Factors | 1972 |
[Lipid metabolism disorders in the rat following parenteral deoxycholate in toxication. Brief report].
Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Injections, Intravenous; Lipid Metabolism; Liver; Liver Regeneration; Lysophosphatidylcholines; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Time Factors | 1973 |
[Cholesterol metabolism and plasma lecithin-cholesterol acyl transferase in experimental hepatitis and cholestasis in the rat].
Topics: Acyltransferases; Animals; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Cholestasis; Cholesterol; Chromatography, Thin Layer; Esters; Hepatitis; Hexosamines; Male; Phosphatidylcholines; Rats; Thiocyanates | 1970 |
Studies on the pharmacological control of hyperlipemia in experimental nephrotic syndrome.
Topics: Animals; Butyrates; Chemical and Drug Induced Liver Injury; Cholesterol; Cholestyramine Resin; Disease Models, Animal; Female; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Liver; Nephrotic Syndrome; Nucleosides; Organ Size; Phosphatidylcholines; Phospholipids; Propionates; Puromycin; Rats; Thyroxine; Triglycerides | 1970 |
Effect of carbon tetrachloride administration on the synthesis of triglycerides and phospholipids in rat liver.
Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Coenzyme A; Depression, Chemical; Female; In Vitro Techniques; Lipids; Liver; Male; Methionine; Microsomes; Mitochondria, Liver; Nucleotides; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Rats; Triglycerides | 1969 |