Page last updated: 2024-09-05

phosphatidylcholines and Atherosclerosis

phosphatidylcholines has been researched along with Atherosclerosis in 87 studies

Research

Studies (87)

TimeframeStudies, this research(%)All Research%
pre-199010 (11.49)18.7374
1990's0 (0.00)18.2507
2000's33 (37.93)29.6817
2010's33 (37.93)24.3611
2020's11 (12.64)2.80

Authors

AuthorsStudies
Allen, RM; Carr, JJ; Castleberry, M; Cavnar, AB; Contreras, DM; Davies, SS; Ifrim, A; Linton, MF; Massick, C; May-Zhang, L; Michell, DL; Raby, CA; Ramirez, MA; Schwendeman, A; Semler, EM; Sheng, Q; Terry, JG; Vickers, KC; Yu, M; Zhu, W1
de Vito, C; Dibner, C; Jornayvaz, FR; Loizides-Mangold, U; Montandon, SA; Somm, E1
Huang, H; Huang, J; Huang, LH; Wang, D1
Chen, C; Chen, X; Liu, P; Peng, C; Yan, B; Zhu, L; Zhu, W1
Bouvy-Liivrand, M; Hartikainen, J; Hippeläinen, M; Kaikkonen, MU; Kansanen, E; Kivelä, A; Kokki, H; Levonen, AL; Linna-Kuosmanen, S; Moreau, PR; Niskanen, H; Tavi, P; Tomas Bosch, V1
Andriamihaja, M; Blachier, F; Blais, A1
Bezrukov, DA; Kaplun, AP; Leskova, GF; Lvovsky, AI1
Bairaktari, ET; Elisaf, M; Ferrannini, E; Kostara, CE; Papathanasiou, A; Tsimihodimos, V1
Aldana-Hernández, P; Azarcoya-Barrera, J; Curtis, JM; Field, CJ; Goruk, S; Jacobs, RL; Leonard, KA; Nelson, R; Richard, C; van der Veen, JN; Zhao, YY1
Chen, Q; Cong, P; Wang, X; Xu, J; Xue, C1
Kiatchoosakun, S; Phetcharaburanin, J; Phrommintikul, A; Senthong, V; Sritara, P; Tatsanavivat, P; Wongvipaporn, C1
Brandtner, EM; Dopheide, JF; Drexel, H; Fraunberger, P; Jylhä, A; Kleber, M; Laaksonen, R; Lääperi, M; Leiherer, A; Mader, A; März, W; Mündlein, A; Ramadani, H; Säly, CH; Vonbank, A1
Chen, Y; Ding, L; Dong, P; Jiang, M; Shi, H; Wen, S; Yang, J; Yang, Y; Zhu, Y1
Inuzuka, K; Iwaki, T; Sano, H; Sasaki, T; Setou, M; Suzuki, Y; Tanaka, H; Umemura, K; Unno, N; Urano, T; Yamamoto, N; Yata, T; Zaima, N1
Vance, DE1
Alonso, A; Huang, F; Li, D; Misialek, JR; Windham, GB; Yu, F1
Gloor, GB; Joris, BR1
Alonso, A; Gottesman, R; Jack, CR; Knopman, D; Li, D; Mielke, MM; Misialek, JR; Mosley, T1
Arnebrant, T; Bengtsson, E; Cárdenas, M; Forsyth, VT; Fredrikson, GN; Haertlein, M; Lind, TK; Lund, R; Maric, S; Moulin, M; Pomorski, TG; Raida, MR; Rogers, S; Wenk, MR1
Cenarro, A; Civeira, F; Cofán, M; Mateo-Gallego, R; Ros, E; Sala-Vila, A1
Arduini, A; Lopaschuk, GD; Ussher, JR1
Berliner, J; Cheng, J; Gugiu, BG; Jung, ME; Koroniak, L; Lee, S; Li, R; Yan, X1
Hazen, SL; Tang, WH1
Drosos, I; Kolios, G; Tavridou, A1
Agardh, HE; Duhlin, A; Forsell, MN; Grasset, EK; Hägglöf, T; Hansson, GK; Karlsson, MC; Ketelhuth, DF; Ovchinnikova, O; Paulsson-Berne, G1
Chen, YE; Freeman, L; Guo, Y; Killion, S; Morin, EE; Ossoli, A; Pryor, M; Remaley, AT; Schwendeman, A; Stonik, J; Sviridov, DO; Thacker, S; Turner, S; Yuan, W; Yuan, Y1
Berliner, JA; Briot, A; Civelek, M; Fishbein, GA; Fishbein, MC; Fogelman, AM; Hoi, K; Hong, C; Iruela-Arispe, ML; Kim, J; Lee, SD; Lusis, AJ; Mack, JJ; Navab, M; Seki, A; Tontonoz, P; Vakili, L; Yu, J1
Kato, S; Miyazawa, T; Nakagawa, K1
Hennig, B; Hoffman, JB; Morris, AJ; Perkins, JT; Petriello, MC; Sunkara, M; Wahlang, B1
Abramowicz, S; Chan, RB; Di Paolo, G; Hsieh, J; Hussain, MM; Ichi, I; Iqbal, J; Koseki, M; Lefkowitch, JH; Molusky, MM; Rader, DJ; Takiguchi, S; Tall, AR; Tascau, L; Welch, CL; Westerterp, M; Yakushiji, E; Yamashita, S1
Aviram, M; Efrat, M; Mahmood, S; Rosenblat, M; Vaya, J1
Kohlwein, SD; Malanovic, N; Rechberger, G; Streith, I; Tehlivets, O; Wolinski, H1
Hara, S; Hatakeyama, S; Ikeda, K; Ishii, T; Ishikawa, Y; Isogai, Y; Itabe, H; Kato, R; Kobayashi, T; Kudo, I; Masuda, S; Murakami, M; Ohtsuki, M; Saka, G; Sato, H; Taguchi, R; Taketomi, Y; Tsutsumi, K; Yamada, J; Yamamoto, K1
Basser, RL; Birjmohun, RS; Bisoendial, RJ; de Kort, H; Franssen, R; Kastelein, JJ; Kuivenhoven, JA; Levels, JH; Meijers, JC; Stroes, ES; van Leuven, SI1
Boyanovsky, B; Forrest, K; Webb, NR; Zack, M1
Brosnan, JT; Francis, GA; Jacobs, RL; Kennedy, B; Su, B; Vance, DE; Vance, JE; Waddington, E; Zhao, Y1
Anantharamaiah, GM; Epand, RF; Epand, RM; Mishra, VK; Palgunachari, MN1
Cooks, RG; Hendrickson, RC; Manicke, NE; Nefliu, M; Reiser, V; Woods, JW; Wu, C1
Fujimoto, H; Kobayashi, H; Ohno, M1
Berliner, JA; Chen, SS; Graeber, TG; Kafi, A; Komisopoulou, E; Martínez-Pinna, R; Titz, B; Zimman, A1
Amar, MJ; D'Souza, W; Demosky, S; Hellerstein, M; Luchoomun, J; Remaley, AT; Stonik, J; Sviridov, D; Turner, S; Voogt, J1
Sahebkar, A1
Cole, LK; Dolinsky, VW; Dyck, JR; Vance, DE1
Rader, DJ; Rak, K1
Allayee, H; Bennett, BJ; Britt, EB; Chung, YM; DiDonato, JA; Dugar, B; Feldstein, AE; Fu, X; Hazen, SL; Klipfell, E; Koeth, R; Levison, BS; Lusis, AJ; Schauer, P; Smith, JD; Tang, WH; Wang, Z; Wu, Y1
Cheng, XW; Enomoto, H; Goto-Inoue, N; Hayasaka, T; Kuzuya, M; Onoue, K; Sasaki, T; Setou, M; Tanaka, H; Unno, N; Zaima, N1
Araujo, JA; Berliner, JA; Che, N; Civelek, M; Kayne, P; Lee, S; Lusis, AJ; Mai, N; Mungrue, IN; Pan, C; Pouldar, D; Romanoski, CE; Vakili, L; Yang, WP; Yin, F1
Fingerle, J; Mary, JL; Ohnsorg, PM; Pech, M; Rohrer, L; von Eckardstein, A1
Alique, M; Badimon, JJ; Badimon, L; Cimmino, G; Fuster, V; Giannarelli, C; Ibanez, B; Pinero, A; Santos-Gallego, CG; Vilahur, G1
Anantharamaiah, GM; Deivanayagam, CCS; Garber, DW; Handattu, SP; McPherson, DT; Mishra, VK; Nayyar, G; Palgunachari, MN; Segrest, JP; Shin, R1
André, P; Atout, R; Carreras, M; Dollet, S; Karabina, SA; Lambeau, G; Lotteau, V; Ninio, E; Payré, C; Perrin-Cocon, L1
Aldover-Macasaet, E; Belgacem, O; Bicker, W; Bochkov, V; Pock, K; Sobal, G; Stübiger, G; Widhalm, K; Willfort-Ehringer, A1
GREENBERG, DM; PILGERAM, LO1
FISCHER, FW; KROETZ, C1
KOZUBSKA-NIEBROJ, M; NIEBROJ, T; SAMOCHOWIEC, L1
LOPUSHANSKII, VI1
BILLIMORIA, JD; MACLAGAN, NF1
DOVGIALLO, GK; GULKO, IS1
OBERHOFFER, G; PUPITA, F; RAPPELLI, A; VACCARINO, A1
PRESS, L1
KONECKI, J; PIETKIEWICZ, W; SAMOCHOWIEC, L1
KOSULINA, ON1
Hirayama, Y; Kotake, H; Miyazawa, T; Oikawa, S; Sawai, T; Sekikawa, A; Tokita, Y; Toyota, T1
Salomon, RG; Zhang, W1
Dever, G; Spickett, CM1
Berliner, JA; Cruz, D; Dun, M; Gharavi, N; Koroniak, L; Li, R; Montoya, D; Mouillesseaux, KP1
Baker, NA; Berliner, JA; Gharavi, NM; Honda, HM; Hsieh, X; Mouillesseaux, KP; Smart, EJ; Yeh, M; Yeung, W1
Leitinger, N1
Pollock, JS; Sullivan, JC1
Karabina, SA; Ninio, E1
Baruch-Oren, T; Berliner, JA; Clark, MJ; Gargalovic, PS; Gharavi, NM; He, A; Kirchgessner, TG; Lusis, AJ; Pagnon, J; Truong, A; Yang, WP1
Ramage, SC; Rufail, ML; van Antwerpen, R1
Erridge, C; Spickett, CM; Webb, DJ1
Bullitt, E; Gantz, D; Jiang, ZG; McKnight, CJ1
Esterbauer, H; Exner, M; Gmeiner, BM; Holzer, G; Kapiotis, S; Kopp, CW; Kronke, G; Leitinger, N; Wagner, O1
Kawamura, A; Matsuo, Y; Miura, S; Rye, KA; Saku, K; Uehara, Y1
Araujo, JA; Berliner, JA; Chang, I; Clark, MJ; Gargalovic, PS; Gharavi, NM; Lusis, AJ; Szeto, WL; Watson, AD1
Cohen, DE; Kanno, K; Roderick, SL; Scapa, EF; Wu, MK1
Bezouglaia, O; Demer, LL; Huang, MS; Lu, J; Morony, S; Tetradis, S; Tintut, Y; Tseng, W; Zhang, Z1
Araujo, JA; Barajas, B; Gong, KW; Horvath, S; Kleinman, M; Li, N; Lusis, AJ; Nel, A; Sioutas, C; Zhao, W1
Alva, JA; Berliner, JA; Fishbein, M; Gharavi, NM; Hong, L; Johnson, J; Lai, C; Mouillesseaux, KP; Pfeffer, LM; Szeto, WL; Wei, L; Yeh, M; Yeung, W1
Benson, R; Dever, GJ; Kennedy, S; Spickett, CM; Wainwright, CL1
Duong, V; Gugiu, BG; Hekimian, A; Herzog, T; Koroniak, L; Mouillesseaux, K; Vondriska, TM; Watson, AD1
Burnand, KG; Davis, B; Douet, LJ; Humphries, J; Koster, G; Macphee, CH; Postle, AD; Scigelova, M; Smith, A; Ward, JM; Woffendin, G1
Balconi, E; Bisgaier, CL; Castano, M; Chaabane, L; Chiesa, G; Krause, B; Lorenzon, P; Lorusso, V; Marchesi, M; Martin, BJ; Miragoli, L; Morisetti, A; Newton, RS; Parolini, C; Sirtori, CR1
Badimon, JJ; Badimon, L; Choi, BG; Cimmino, G; Fuster, V; Ibanez, B; Krause, B; Pinero, A; Santos-Gallego, CG; Speidl, WS; Vilahur, G; Zafar, MU1
Aceves, M; Crespo, MS; Dueñas, AI; Fernández-Pisonero, I; García-Rodríguez, C; Gómez, C; Orduña, A1

Reviews

12 review(s) available for phosphatidylcholines and Atherosclerosis

ArticleYear
Roles of Reconstituted High-Density Lipoprotein Nanoparticles in Cardiovascular Disease: A New Paradigm for Drug Discovery.
    International journal of molecular sciences, 2020, Jan-23, Volume: 21, Issue:3

    Topics: Animals; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; Biomimetics; Drug Discovery; Humans; Lipoproteins, HDL; Macrophages; Mice; Molecular Imaging; Nanoparticles; Phosphatidylcholines

2020
The mechanisms of lysophosphatidylcholine in the development of diseases.
    Life sciences, 2020, Apr-15, Volume: 247

    Topics: Animals; Arteries; Atherosclerosis; Blood Glucose; Cardiovascular Diseases; Cell Movement; Cytokines; Endothelial Cells; Humans; Inflammation; Insulin Resistance; Lipoproteins, LDL; Lymphocytes; Lysophosphatidylcholines; Macrophages; Myocytes, Smooth Muscle; Neoplasms; Nervous System Diseases; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A2; Pyroptosis; Receptors, G-Protein-Coupled; Toll-Like Receptors

2020
Sulfur-Containing Amino Acids and Lipid Metabolism.
    The Journal of nutrition, 2020, 10-01, Volume: 150, Issue:Suppl 1

    Topics: Amino Acids, Sulfur; Animals; Atherosclerosis; Betaine; Cholesterol; Cysteine; Dietary Proteins; Dietary Supplements; Fatty Liver; Glutathione; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; Sulfur; Sulfur Compounds; Taurine

2020
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
    Current opinion in lipidology, 2019, Volume: 30, Issue:2

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, Volatile; Gastrointestinal Microbiome; Genomics; High-Throughput Nucleotide Sequencing; Humans; Lipid Metabolism; Metabolic Syndrome; Methylamines; Phosphatidylcholines; RNA, Ribosomal, 16S; T-Lymphocytes, Helper-Inducer; Triglycerides

2019
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
    Atherosclerosis, 2013, Volume: 231, Issue:2

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Insulin Resistance; Intestines; Liver; Methylamines; Mice; Microbiota; Muscle, Skeletal; Myocardial Ischemia; Phosphatidylcholines; Risk

2013
The contributory role of gut microbiota in cardiovascular disease.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:10

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines

2014
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
    Metabolism: clinical and experimental, 2015, Volume: 64, Issue:4

    Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methylamines; Microbiota; Phosphatidylcholines

2015
Determination of Phosphatidylcholine Hydroperoxide (PCOOH) as a Marker of Membrane Lipid Peroxidation.
    Journal of nutritional science and vitaminology, 2015, Volume: 61 Suppl

    Topics: Atherosclerosis; Biomarkers; Chromatography, High Pressure Liquid; Humans; Isomerism; Linoleic Acids; Lipid Peroxidation; Lipid Peroxides; Oxidative Stress; Phosphatidylcholines; Tandem Mass Spectrometry

2015
BIOCHEMISTRY OF ATHEROSCLEROSIS.
    Biochemical clinics, 1963, Volume: 2

    Topics: Arteriosclerosis; Atherosclerosis; Blood Coagulation Tests; Dietary Fats; Fatty Acids; Fibrinolysis; Humans; Lecithins; Lipids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids

1963
Oxidized phospholipids, isolevuglandins, and atherosclerosis.
    Molecular nutrition & food research, 2005, Volume: 49, Issue:11

    Topics: Aldehydes; Animals; Atherosclerosis; Blood Proteins; Cross-Linking Reagents; Fatty Acids, Unsaturated; Free Radicals; Humans; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Phospholipids; Platelet Activation; Prostaglandins; Protein Binding; Risk Factors

2005
Plasma PAF-acetylhydrolase: an unfulfilled promise?
    Biochimica et biophysica acta, 2006, Volume: 1761, Issue:11

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anti-Inflammatory Agents; Asthma; Atherosclerosis; Biomarkers; Disease Models, Animal; Humans; Inflammation; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Phosphatidylcholines; Platelet Activating Factor; Recombinant Proteins; Sepsis

2006
Structure and function of phosphatidylcholine transfer protein (PC-TP)/StarD2.
    Biochimica et biophysica acta, 2007, Volume: 1771, Issue:6

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Biological Transport; Cattle; Lipoproteins, HDL; Liver; Mice; Mice, Knockout; Models, Molecular; Molecular Structure; Phosphatidylcholines; Phospholipid Transfer Proteins; Protein Structure, Tertiary; Pulmonary Surfactants; Species Specificity; Tissue Distribution

2007

Trials

1 trial(s) available for phosphatidylcholines and Atherosclerosis

ArticleYear
The dietary soy flavonoid genistein abrogates tissue factor induction in endothelial cells induced by the atherogenic oxidized phospholipid oxPAPC.
    Thrombosis research, 2007, Volume: 120, Issue:1

    Topics: Anticoagulants; Atherosclerosis; Cell Culture Techniques; Endothelial Cells; Genistein; Humans; Phosphatidylcholines; Thromboplastin

2007

Other Studies

74 other study(ies) available for phosphatidylcholines and Atherosclerosis

ArticleYear
Elucidation of physico-chemical principles of high-density lipoprotein-small RNA binding interactions.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:6

    Topics: Animals; Apolipoprotein A-I; Atherosclerosis; Humans; Lipoproteins, HDL; Mice; Phosphatidylcholines; RNA, Small Untranslated

2022
Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism.
    Scientific reports, 2019, 11-14, Volume: 9, Issue:1

    Topics: Animals; Atherosclerosis; Choline; Diet; Diet, Atherogenic; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Lipidomics; Male; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sphingolipids

2019
NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli.
    Cardiovascular research, 2021, 04-23, Volume: 117, Issue:5

    Topics: Atherosclerosis; Cells, Cultured; Cellular Senescence; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Human Umbilical Vein Endothelial Cells; Humans; MicroRNAs; NF-E2-Related Factor 2; Oxidation-Reduction; Phosphatidylcholines; Plaque, Atherosclerotic; Transcriptome

2021
Effect of Phosphatidylcholine Nanosomes on Phospholipid Composition of the Plasma Membranes in Liver Cells and Blood Serum in Experimental Atherosclerosis.
    Bulletin of experimental biology and medicine, 2020, Volume: 170, Issue:2

    Topics: Animals; Antioxidants; Atherosclerosis; Cardiolipins; Cell Membrane; Diet, Atherogenic; Immune System; Lipoproteins; Liver; Lysophosphatidylcholines; Nanoparticles; Phosphatidylcholines; Phospholipids; Rabbits; Risk Factors; Thrombosis

2020
Early Signs of Atherogenic Features in the HDL Lipidomes of Normolipidemic Patients Newly Diagnosed with Type 2 Diabetes.
    International journal of molecular sciences, 2020, Nov-22, Volume: 21, Issue:22

    Topics: Aged; Atherosclerosis; Cholesterol, HDL; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Lipidomics; Lipoproteins, HDL; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Sphingomyelins; Triglycerides

2020
Dietary phosphatidylcholine supplementation reduces atherosclerosis in Ldlr
    The Journal of nutritional biochemistry, 2021, Volume: 92

    Topics: Animals; Atherosclerosis; Diet, High-Fat; Dietary Supplements; Gene Deletion; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Receptors, LDL

2021
Lipidomics Approach in High-Fat-Diet-Induced Atherosclerosis Dyslipidemia Hamsters: Alleviation Using Ether-Phospholipids in Sea Urchin.
    Journal of agricultural and food chemistry, 2021, Aug-18, Volume: 69, Issue:32

    Topics: Animals; Atherosclerosis; Cricetinae; Diet, High-Fat; Dyslipidemias; Lipidomics; Phosphatidylcholines; Phospholipid Ethers; Sea Urchins

2021
Gut microbiota-generated metabolite, trimethylamine-N-oxide, and subclinical myocardial damage: a multicenter study from Thailand.
    Scientific reports, 2021, 07-22, Volume: 11, Issue:1

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Cardiovascular Diseases; Case-Control Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Phosphatidylcholines; Risk Assessment; Thailand; Troponin T

2021
Lipid profiles of patients with manifest coronary versus peripheral atherosclerosis - Is there a difference?
    Journal of internal medicine, 2021, Volume: 290, Issue:6

    Topics: Atherosclerosis; Ceramides; Coronary Artery Disease; Diabetes Mellitus, Type 2; Humans; Lipids; Lipoproteins; Peripheral Arterial Disease; Phosphatidylcholines; Risk Factors

2021
Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE
    Atherosclerosis, 2017, Volume: 262

    Topics: Animals; Atherosclerosis; Biomarkers; Chromatography, High Pressure Liquid; Diet, High-Fat; Discriminant Analysis; Disease Models, Animal; Disease Progression; Dyslipidemias; Genetic Predisposition to Disease; Lipids; Male; Mass Spectrometry; Metabolomics; Mice, Inbred C57BL; Mice, Knockout, ApoE; Pattern Recognition, Automated; Phenotype; Phosphatidylcholines; Plaque, Atherosclerotic; Sphingomyelins; Sphingosine

2017
Lysophosphatidylcholine Acyltransferase-3 Expression Is Associated with Atherosclerosis Progression.
    Journal of vascular research, 2017, Volume: 54, Issue:4

    Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Aged; Aged, 80 and over; Animals; Apolipoproteins E; Arachidonic Acid; Arteries; Atherosclerosis; Disease Models, Animal; Disease Progression; Female; Humans; Lysophosphatidylcholines; Male; Mice, Inbred BALB C; Mice, Knockout; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylcholines; Plaque, Atherosclerotic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation

2017
From masochistic enzymology to mechanistic physiology and disease.
    The Journal of biological chemistry, 2017, 10-20, Volume: 292, Issue:42

    Topics: Animals; Atherosclerosis; Choline-Phosphate Cytidylyltransferase; Diet; Embryo, Mammalian; Gene Targeting; History, 20th Century; History, 21st Century; Humans; Insulin Resistance; Mice; Mice, Knockout; Obesity; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase

2017
Independent Association of Plasma Hydroxysphingomyelins With Physical Function in the Atherosclerosis Risk in Communities (ARIC) Study.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2018, 07-09, Volume: 73, Issue:8

    Topics: Aged; Arginine; Atherosclerosis; Cross-Sectional Studies; Female; Hand Strength; Humans; Linear Models; Male; Phosphatidylcholines; Physical Fitness; Risk Factors; Sphingomyelins; Walking Speed

2018
Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS).
    International journal of molecular sciences, 2019, Apr-09, Volume: 20, Issue:7

    Topics: Aged; Aged, 80 and over; Atherosclerosis; Brain; Female; Humans; Linear Models; Magnetic Resonance Imaging; Male; Neurodegenerative Diseases; Phosphatidylcholines; Prospective Studies; Risk Assessment; Sphingomyelins

2019
Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes.
    Scientific reports, 2019, 05-20, Volume: 9, Issue:1

    Topics: Atherosclerosis; Cell Membrane; Cholesterol; Humans; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Membranes; Neutrons; Phosphatidylcholines; Scattering, Small Angle

2019
Eicosapentaenoic acid in serum phospholipids relates to a less atherogenic lipoprotein profile in subjects with familial hypercholesterolemia.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:9

    Topics: Adult; Alcohol Drinking; Animals; Atherosclerosis; Biomarkers; Cross-Sectional Studies; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fasting; Female; Fishes; Humans; Hyperlipoproteinemia Type II; Lipoproteins, HDL; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Phospholipids; Risk Factors; Surveys and Questionnaires; Triglycerides

2013
Fatty acid epoxyisoprostane E2 stimulates an oxidative stress response in endothelial cells.
    Biochemical and biophysical research communications, 2014, Jan-31, Volume: 444, Issue:1

    Topics: Apoptosis Regulatory Proteins; Atherosclerosis; Cells, Cultured; Endothelial Cells; Heme Oxygenase-1; Humans; Isoprostanes; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylcholines; Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation

2014
Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response.
    Proceedings of the National Academy of Sciences of the United States of America, 2015, Apr-21, Volume: 112, Issue:16

    Topics: Aging; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; B-Lymphocytes; Cholesterol; Clone Cells; Epitopes; Germinal Center; Inflammasomes; Inflammation; Lipoproteins, LDL; Lymphocyte Activation; Mice, Inbred C57BL; Oxidation-Reduction; Phosphatidylcholines; Spleen

2015
The effect of phospholipid composition of reconstituted HDL on its cholesterol efflux and anti-inflammatory properties.
    Journal of lipid research, 2015, Volume: 56, Issue:9

    Topics: Animals; Apolipoprotein A-I; Atherosclerosis; Cholesterol; Humans; Inflammation; Lipoproteins, HDL; Mice; Peptides; Phosphatidylcholines; Phospholipids; Rats; Sphingomyelins

2015
Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.
    The Journal of experimental medicine, 2015, Nov-16, Volume: 212, Issue:12

    Topics: Adult; Animals; Atherosclerosis; Cell Line, Tumor; Cells, Cultured; Diet, High-Fat; Endothelial Cells; Female; Humans; Inflammation; Interleukin-1beta; Lipids; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Phosphatidylcholines; Receptor, Notch1; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcriptome; Tumor Necrosis Factor-alpha

2015
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.
    The Journal of nutritional biochemistry, 2016, Volume: 33

    Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Choline; Deuterium; Dietary Fats; Environmental Pollutants; Enzyme Induction; Food-Drug Interactions; Liver; Male; Methylamines; Mice, Inbred C57BL; Oxygenases; Phosphatidylcholines; Polychlorinated Biphenyls; Random Allocation; Up-Regulation

2016
TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
    Nature, 2016, 07-14, Volume: 535, Issue:7611

    Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholesterol, Dietary; Cholesterol, HDL; Diet, High-Fat; Fatty Acids, Unsaturated; Fatty Liver; Female; Gene Expression Regulation; Hepatocytes; Ligands; Lipogenesis; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Liver X Receptors; Male; Mice; Orphan Nuclear Receptors; Phosphatidylcholines; Protein Stability; Proteolysis; Receptors, LDL; Sterol Regulatory Element Binding Protein 1; Ubiquitination

2016
Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies.
    Atherosclerosis, 2009, Volume: 202, Issue:2

    Topics: Animals; Aryldialkylphosphatase; Atherosclerosis; Catalysis; Cell Line; Cholesterol, HDL; Dietary Fats; Enzyme Activation; Fatty Acids; In Vitro Techniques; Macrophages; Mice; Mice, Inbred BALB C; Olive Oil; Phosphatidylcholines; Plant Oils

2009
S-adenosyl-L-homocysteine hydrolase, key enzyme of methylation metabolism, regulates phosphatidylcholine synthesis and triacylglycerol homeostasis in yeast: implications for homocysteine as a risk factor of atherosclerosis.
    The Journal of biological chemistry, 2008, Aug-29, Volume: 283, Issue:35

    Topics: Adenosylhomocysteinase; Atherosclerosis; Down-Regulation; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Homeostasis; Homocysteine; Humans; Membrane Proteins; Methylation; Myo-Inositol-1-Phosphate Synthase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Repressor Proteins; Risk Factors; S-Adenosylhomocysteine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triglycerides

2008
Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.
    The Journal of biological chemistry, 2008, Nov-28, Volume: 283, Issue:48

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Bee Venoms; Diet, Atherogenic; Foam Cells; Group III Phospholipases A2; Isoenzymes; Lipoproteins, HDL; Lipoproteins, LDL; Lysophosphatidylcholines; Mice; Mice, Transgenic; Phosphatidylcholines; Protein Processing, Post-Translational; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity

2008
ApoAI-phosphatidylcholine infusion neutralizes the atherothrombotic effects of C-reactive protein in humans.
    Journal of thrombosis and haemostasis : JTH, 2009, Volume: 7, Issue:2

    Topics: Adult; Apolipoprotein A-I; Atherosclerosis; C-Reactive Protein; Endothelial Cells; Humans; Inflammation; Male; Middle Aged; Phosphatidylcholines; Recombinant Proteins; Thrombosis

2009
The capacity of group V sPLA2 to increase atherogenicity of ApoE-/- and LDLR-/- mouse LDL in vitro predicts its atherogenic role in vivo.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:4

    Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Collagen; Dietary Fats; Disease Models, Animal; Female; Foam Cells; Group V Phospholipases A2; Hydrolysis; Lipoproteins, LDL; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Receptors, LDL; Sphingomyelins; Time Factors

2009
Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2009, Volume: 29, Issue:9

    Topics: Animals; Apolipoproteins B; Atherosclerosis; Cholesterol; Cholesterol Esters; Disease Models, Animal; Female; Homocysteine; Kinetics; Lipoproteins, IDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Receptors, LDL; Triglycerides

2009
Anti-inflammatory peptides grab on to the whiskers of atherogenic oxidized lipids.
    Biochimica et biophysica acta, 2009, Volume: 1788, Issue:9

    Topics: Anti-Inflammatory Agents; Atherosclerosis; Calorimetry, Differential Scanning; Lipid Bilayers; Lipids; Oxidation-Reduction; Peptides; Phosphatidylcholines; Phospholipid Ethers; Phosphorylcholine

2009
Imaging of lipids in atheroma by desorption electrospray ionization mass spectrometry.
    Analytical chemistry, 2009, Nov-01, Volume: 81, Issue:21

    Topics: Atherosclerosis; Betaine; Cholesterol; Humans; Phosphatidylcholines; Phospholipids; Spectrometry, Mass, Electrospray Ionization; Sphingomyelins

2009
Age-induced reduction in mitochondrial manganese superoxide dismutase activity and tolerance of macrophages against apoptosis induced by oxidized low density lipoprotein.
    Circulation journal : official journal of the Japanese Circulation Society, 2010, Volume: 74, Issue:2

    Topics: Adult; Aging; Apoptosis; Atherosclerosis; Cells, Cultured; Down-Regulation; Female; Genotype; Humans; Leukocytes; Lipoproteins, LDL; Macrophages; Male; Middle Aged; Mitochondria; Oxidative Stress; Phenotype; Phosphatidylcholines; Superoxide Dismutase; Young Adult

2010
Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis.
    Journal of proteome research, 2010, Jun-04, Volume: 9, Issue:6

    Topics: Amino Acid Sequence; Animals; Aorta; Atherosclerosis; Cardiac Myosins; Cattle; Cells, Cultured; Chromatography, Ion Exchange; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Molecular Sequence Data; Myosin Light Chains; Peptide Fragments; Phosphatidylcholines; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Receptor, TIE-1; Reproducibility of Results; Signal Transduction

2010
5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 334, Issue:2

    Topics: Animals; Aorta; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cholesterol; Female; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Peptides; Phosphatidylcholines; Rats; Rats, Sprague-Dawley

2010
Phosphatidylcholine-rich nanoliposomes: potential tools for serum C-reactive protein reduction?
    Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:1

    Topics: Atherosclerosis; C-Reactive Protein; Humans; Liposomes; Nanoparticles; Phosphatidylcholines

2011
Impaired phosphatidylcholine biosynthesis reduces atherosclerosis and prevents lipotoxic cardiac dysfunction in ApoE-/- Mice.
    Circulation research, 2011, Mar-18, Volume: 108, Issue:6

    Topics: Aging; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Heart; Heart Diseases; Lipid Metabolism; Lipoproteins; Liver; Mice; Mice, Knockout; Myocardium; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Triglycerides

2011
Cardiovascular disease: the diet-microbe morbid union.
    Nature, 2011, Apr-07, Volume: 472, Issue:7341

    Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Choline; Diet; Dietary Fats; Gastrointestinal Tract; Humans; Liver; Metabolomics; Methylamines; Mice; Oxygenases; Phosphatidylcholines; Probiotics; Risk Assessment

2011
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
    Nature, 2011, Apr-07, Volume: 472, Issue:7341

    Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; Diet; Dietary Fats; Female; Gastrointestinal Tract; Gene Expression Regulation; Germ-Free Life; Humans; Liver; Macrophages; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Oxygenases; Phenotype; Phosphatidylcholines; Receptors, Scavenger; Risk Assessment

2011
Imaging mass spectrometry-based histopathologic examination of atherosclerotic lesions.
    Atherosclerosis, 2011, Volume: 217, Issue:2

    Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Calcinosis; Cholesterol Esters; Disease Models, Animal; Humans; Linoleic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peripheral Arterial Disease; Phosphatidylcholines; Predictive Value of Tests; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triglycerides

2011
Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.
    Circulation research, 2011, Aug-19, Volume: 109, Issue:5

    Topics: Adult; Atherosclerosis; Cells, Cultured; Endothelium, Vascular; Gene Expression Profiling; Gene Regulatory Networks; Heme Oxygenase-1; Humans; Phosphatidylcholines

2011
Trimerized apolipoprotein A-I (TripA) forms lipoproteins, activates lecithin: cholesterol acyltransferase, elicits lipid efflux, and is transported through aortic endothelial cells.
    Biochimica et biophysica acta, 2011, Volume: 1811, Issue:12

    Topics: Animals; Aorta; Apolipoprotein A-I; Atherosclerosis; ATP-Binding Cassette Transporters; Cardiovascular Agents; Cattle; Coronary Disease; Endothelial Cells; Gene Silencing; Humans; Kinetics; Lipoproteins, HDL; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Protein Binding; Protein Transport; Recombinant Proteins; RNA, Small Interfering

2011
Recombinant HDL(Milano) exerts greater anti-inflammatory and plaque stabilizing properties than HDL(wild-type).
    Atherosclerosis, 2012, Volume: 220, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Abdominal; Aortic Diseases; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Caspase 3; CD36 Antigens; Cell Line; Chemokine CCL2; Cholesterol; Cyclooxygenase 2; Disease Models, Animal; Infusions, Intravenous; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Macrophages; Magnetic Resonance Imaging; Matrix Metalloproteinase 2; Oxidative Stress; Phosphatidylcholines; Rabbits; Recombinant Proteins; Time Factors

2012
Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptides.
    Journal of lipid research, 2012, Volume: 53, Issue:5

    Topics: Animals; Apolipoprotein A-I; Arginine; Aryldialkylphosphatase; Atherosclerosis; Chemical Phenomena; Cholesterol; Female; Gene Deletion; Guanidine; Humans; Lipoproteins, HDL; Mice; Oxidation-Reduction; Peptidomimetics; Phosphatidylcholines; Protein Structure, Secondary; Protein Unfolding; Reactive Oxygen Species; Unilamellar Liposomes

2012
Human group X secreted phospholipase A2 induces dendritic cell maturation through lipoprotein-dependent and -independent mechanisms.
    Atherosclerosis, 2012, Volume: 222, Issue:2

    Topics: Atherosclerosis; Coculture Techniques; Dendritic Cells; Fatty Acids, Nonesterified; Group X Phospholipases A2; Humans; Hydrolysis; Interferon-gamma; Lipoproteins, LDL; Lysophosphatidylcholines; Phenotype; Phosphatidylcholines; Th1 Cells

2012
Targeted profiling of atherogenic phospholipids in human plasma and lipoproteins of hyperlipidemic patients using MALDI-QIT-TOF-MS/MS.
    Atherosclerosis, 2012, Volume: 224, Issue:1

    Topics: Adolescent; Atherosclerosis; Biomarkers; Child; Cholesterol, LDL; Female; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Lipoproteins; Lysophosphatidylcholines; Male; Phosphatidylcholines; Phospholipids; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sphingomyelins; Tandem Mass Spectrometry; Young Adult

2012
Susceptibility to experimental atherosclerosis and the methylation of ethanolamine 1,2-C14 to phosphatidyl choline.
    Science (New York, N.Y.), 1954, Nov-05, Volume: 120, Issue:3123

    Topics: Amino Alcohols; Arteriosclerosis; Atherosclerosis; Choline; Disease Susceptibility; Ethanolamine; Ethanolamines; Methylation; Phosphatidylcholines

1954
[Beta-Lipoproteins & their relation to age groups, to stages of progressive atherosclerosis & to various eye diseases].
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1957, Volume: 13, Issue:1-4

    Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Eye Diseases; Humans; Lecithins; Lipoproteins; Lipoproteins, LDL; Phosphatidylcholines; Vascular Diseases

1957
[The effect of "essential" phospholipids on the histochemistry of the adrenal cortex during experimental atherosclerosis in rats].
    Arzneimittel-Forschung, 1962, Volume: 12

    Topics: Adrenal Cortex; Animals; Arteriosclerosis; Atherosclerosis; Phosphatidylcholines; Phospholipids; Rats

1962
[APPLICATION OF VITAMIN B1 AND B12 IN PATIENTS WITH ATHEROSCLEROSIS].
    Sovetskaia meditsina, 1963, Volume: 27

    Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Corrinoids; Hematinics; Humans; Lecithins; Phosphatidylcholines; Thiamine; Vitamin B 12

1963
[USE OF NICOTINIC ACID IN ATHEROSCLEROSIS].
    Terapevticheskii arkhiv, 1963, Volume: 35

    Topics: Arteriosclerosis; Atherosclerosis; Blood Protein Electrophoresis; Cholesterol; Lecithins; Niacin; Nicotinic Acids; Pharmacology; Phosphatidylcholines

1963
[CONTRIBUTION TO THE STUDY OF THE THERAPY OF ATHEROSCLEROSIS WITH ESSENTIAL PHOSPHOLIPIDS].
    La Clinica terapeutica, 1964, Jan-31, Volume: 28

    Topics: Arteriosclerosis; Atherosclerosis; Blood Proteins; Cholesterol; Coronary Disease; Lipids; Lipoproteins; Phosphatidylcholines; Phospholipids

1964
[ATHEROSCLEROSIS AND PLASMATIC ATHEROGENIC INDICES].
    El Dia medico, 1964, Apr-13, Volume: 36

    Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Humans; Lecithins; Lipids; Lipoproteins; Phosphatidylcholines; Phospholipids

1964
[Parenteral administration of "essential" phospholipids in experimental atherosclerosis in rats].
    Arzneimittel-Forschung, 1962, Volume: 12

    Topics: Animals; Arteriosclerosis; Atherosclerosis; Phosphatidylcholines; Phospholipids; Rats

1962
[Effect of soy lecithin and a low cholesterol diet on the course of atherosclerosis].
    Trudy Leningradskogo sanitarno-gigienicheskogo meditsinskogo instituta, 1962, Volume: 67

    Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Diet; Glycine max; Humans; Lecithins; Nutrition Assessment; Phosphatidylcholines

1962
Fructose ingestion enhances atherosclerosis and deposition of advanced glycated end-products in cholesterol-fed rabbits.
    Journal of atherosclerosis and thrombosis, 2005, Volume: 12, Issue:5

    Topics: Animals; Atherosclerosis; Cholesterol; Fructose; Glycation End Products, Advanced; Hyperlipidemias; Lipid Peroxidation; Male; Oxidative Stress; Phosphatidylcholines; Rabbits

2005
Studies of phospholipid oxidation by electrospray mass spectrometry: from analysis in cells to biological effects.
    BioFactors (Oxford, England), 2005, Volume: 24, Issue:1-4

    Topics: Animals; Atherosclerosis; Chlorohydrins; Chromatography, Liquid; Erythrocytes; Fatty Acids; Humans; Hypochlorous Acid; Lipid Peroxidation; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Phospholipids; Rabbits; Spectrometry, Mass, Electrospray Ionization

2005
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC.
    Circulation research, 2006, Mar-17, Volume: 98, Issue:5

    Topics: Alprostadil; Atherosclerosis; Cells, Cultured; Dinoprostone; Foam Cells; Humans; Interleukin-10; Isoprostanes; Macrophages; Monocytes; Oxidation-Reduction; Phosphatidylcholines; Phospholipid Ethers; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthones

2006
Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.
    Circulation research, 2006, Mar-31, Volume: 98, Issue:6

    Topics: Animals; Atherosclerosis; Cattle; Cells, Cultured; CSK Tyrosine-Protein Kinase; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Humans; Interleukin-8; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phospholipid Ethers; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; src-Family Kinases; Sterol Regulatory Element Binding Proteins; Superoxides

2006
A rancid culprit in vascular inflammation acts on the prostaglandin receptor EP2.
    Circulation research, 2006, Mar-17, Volume: 98, Issue:5

    Topics: Atherosclerosis; Cyclic AMP; Dinoprostone; Humans; Isoprostanes; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A; Phospholipid Ethers; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype

2006
Coupled and uncoupled NOS: separate but equal? Uncoupled NOS in endothelial cells is a critical pathway for intracellular signaling.
    Circulation research, 2006, Mar-31, Volume: 98, Issue:6

    Topics: Animals; Atherosclerosis; Endothelial Cells; Humans; Interleukin-8; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylcholines; Phosphorylation; Signal Transduction; Sterol Regulatory Element Binding Proteins; Superoxides

2006
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells.
    Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:11

    Topics: Activating Transcription Factor 4; Aorta; Atherosclerosis; Cells, Cultured; Chromosome Mapping; DNA-Binding Proteins; Endothelial Cells; Gene Expression; Gene Expression Regulation; Humans; Immunologic Techniques; Inflammation; Nuclear Proteins; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Protein Folding; Regulatory Factor X Transcription Factors; Tissue Distribution; Transcription Factors; X-Box Binding Protein 1

2006
C-reactive protein inhibits in vitro oxidation of low-density lipoprotein.
    FEBS letters, 2006, Oct-02, Volume: 580, Issue:22

    Topics: Antibodies, Monoclonal; Atherosclerosis; C-Reactive Protein; Copper; Humans; Lipoproteins, LDL; Liposomes; Oxidation-Reduction; Phosphatidylcholines

2006
Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression.
    Atherosclerosis, 2007, Volume: 193, Issue:1

    Topics: Atherosclerosis; Base Sequence; Cell Line; Cells, Cultured; DNA Primers; Endothelial Cells; Gene Expression; Humans; Interleukin-8; Lipids; NF-kappa B; Phosphatidylcholines; Promoter Regions, Genetic; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 4; Transfection

2007
Defining lipid-interacting domains in the N-terminal region of apolipoprotein B.
    Biochemistry, 2006, Oct-03, Volume: 45, Issue:39

    Topics: Apolipoproteins B; Atherosclerosis; Carrier Proteins; Chylomicrons; Egg Proteins; Egg Proteins, Dietary; Endoplasmic Reticulum; Humans; Kinetics; Lipoproteins, VLDL; Models, Molecular; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary

2006
Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation.
    Atherosclerosis, 2007, Volume: 194, Issue:1

    Topics: Animals; Atherosclerosis; Cell Division; Cells, Cultured; CHO Cells; Cholesterol; Coronary Vessels; Cricetinae; Cricetulus; Endothelial Cells; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipoproteins, HDL; Lysophospholipids; Macrophages; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligonucleotides, Antisense; Phosphatidylcholines; Proto-Oncogene Proteins c-akt; ras Proteins; Sphingosine

2007
High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:6

    Topics: Anti-Inflammatory Agents; Antioxidants; Aorta; Atherosclerosis; Cell Adhesion; Cells, Cultured; Chemotaxis; CSK Tyrosine-Protein Kinase; Cytokines; Endothelial Cells; Gene Expression; Humans; Inflammation; Isoprostanes; Lipid Metabolism; Lipoproteins, HDL; Monocytes; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylcholines; Phosphorylation; Protein-Tyrosine Kinases; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Sterol Regulatory Element Binding Proteins; Sterols; Transcription Factors

2007
Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts.
    The Journal of biological chemistry, 2007, Jul-20, Volume: 282, Issue:29

    Topics: Animals; Atherosclerosis; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Mice; Nuclear Receptor Subfamily 4, Group A, Member 2; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Parathyroid Hormone; Phosphatidylcholines; Phospholipids; Phosphorylcholine; Signal Transduction; Transcription Factors; Transforming Growth Factor beta

2007
Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells.
    Genome biology, 2007, Volume: 8, Issue:7

    Topics: Air Pollutants; Atherosclerosis; Cell Line; Endothelium, Vascular; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Genome, Human; Heme Oxygenase-1; Humans; Phosphatidylcholines; Vasculitis; Vehicle Emissions

2007
Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo.
    The Journal of biological chemistry, 2007, Oct-26, Volume: 282, Issue:43

    Topics: Animals; Aorta; Atherosclerosis; Capillaries; Cells, Cultured; Chromatin Immunoprecipitation; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; In Vitro Techniques; Interleukin-8; Janus Kinase 2; Mice; Mice, Knockout; Models, Biological; Oxidation-Reduction; Phosphatidylcholines; Phosphorylation; Plasmids; RNA, Small Interfering; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transcription, Genetic; Transfection

2007
Phospholipid chlorohydrin induces leukocyte adhesion to ApoE-/- mouse arteries via upregulation of P-selectin.
    Free radical biology & medicine, 2008, Feb-01, Volume: 44, Issue:3

    Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteries; Atherosclerosis; Cell Adhesion; Chlorohydrins; Hypochlorous Acid; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Lipoproteins, LDL; Mice; Mice, Knockout; Nitrates; P-Selectin; Phosphatidylcholines; Phospholipids; Pravastatin; Reactive Oxygen Species; Up-Regulation

2008
Protein targets of oxidized phospholipids in endothelial cells.
    Journal of lipid research, 2008, Volume: 49, Issue:3

    Topics: Atherosclerosis; Biotinylation; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Humans; Inflammation; Lipid Peroxidation; Phosphatidylcholines; Phospholipids; Protein Binding; Proteins

2008
Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoprotein.
    The Journal of biological chemistry, 2008, Mar-07, Volume: 283, Issue:10

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Atherosclerosis; Biomarkers; Enzyme Inhibitors; Fatty Acids; Humans; Inflammation; Lipoproteins, LDL; Lysophospholipids; Oxidation-Reduction; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization

2008
Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1-palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: in vivo assessment by intravascular ultrasound and magnetic resonance im
    Journal of the American College of Cardiology, 2008, Mar-18, Volume: 51, Issue:11

    Topics: Animals; Anticholesteremic Agents; Apolipoprotein A-I; Atherosclerosis; Carotid Artery, Common; Carotid Stenosis; Cholesterol, HDL; Disease Models, Animal; Dose-Response Relationship, Drug; Magnetic Resonance Imaging; Male; Phosphatidylcholines; Rabbits; Random Allocation; Ultrasonography

2008
Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: magnetic resonance imaging study in an experimental model of atherosclerosis.
    Journal of the American College of Cardiology, 2008, Mar-18, Volume: 51, Issue:11

    Topics: Animals; Anticholesteremic Agents; Aortic Diseases; Apolipoprotein A-I; Atherosclerosis; Disease Models, Animal; Gene Expression; Male; Phosphatidylcholines; Rabbits; Random Allocation

2008
Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate.
    Cardiovascular research, 2008, Aug-01, Volume: 79, Issue:3

    Topics: Atherosclerosis; Cell Line; Chemokines; Enzyme Inhibitors; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lysophospholipids; NF-kappa B; Phagocytes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; ras Proteins; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Time Factors; Toll-Like Receptor 2; Transcription, Genetic; Transfection

2008