phosphatidylcholines has been researched along with Atherosclerosis in 87 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (11.49) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 33 (37.93) | 29.6817 |
| 2010's | 33 (37.93) | 24.3611 |
| 2020's | 11 (12.64) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, RM; Carr, JJ; Castleberry, M; Cavnar, AB; Contreras, DM; Davies, SS; Ifrim, A; Linton, MF; Massick, C; May-Zhang, L; Michell, DL; Raby, CA; Ramirez, MA; Schwendeman, A; Semler, EM; Sheng, Q; Terry, JG; Vickers, KC; Yu, M; Zhu, W | 1 |
| de Vito, C; Dibner, C; Jornayvaz, FR; Loizides-Mangold, U; Montandon, SA; Somm, E | 1 |
| Huang, H; Huang, J; Huang, LH; Wang, D | 1 |
| Chen, C; Chen, X; Liu, P; Peng, C; Yan, B; Zhu, L; Zhu, W | 1 |
| Bouvy-Liivrand, M; Hartikainen, J; Hippeläinen, M; Kaikkonen, MU; Kansanen, E; Kivelä, A; Kokki, H; Levonen, AL; Linna-Kuosmanen, S; Moreau, PR; Niskanen, H; Tavi, P; Tomas Bosch, V | 1 |
| Andriamihaja, M; Blachier, F; Blais, A | 1 |
| Bezrukov, DA; Kaplun, AP; Leskova, GF; Lvovsky, AI | 1 |
| Bairaktari, ET; Elisaf, M; Ferrannini, E; Kostara, CE; Papathanasiou, A; Tsimihodimos, V | 1 |
| Aldana-Hernández, P; Azarcoya-Barrera, J; Curtis, JM; Field, CJ; Goruk, S; Jacobs, RL; Leonard, KA; Nelson, R; Richard, C; van der Veen, JN; Zhao, YY | 1 |
| Chen, Q; Cong, P; Wang, X; Xu, J; Xue, C | 1 |
| Kiatchoosakun, S; Phetcharaburanin, J; Phrommintikul, A; Senthong, V; Sritara, P; Tatsanavivat, P; Wongvipaporn, C | 1 |
| Brandtner, EM; Dopheide, JF; Drexel, H; Fraunberger, P; Jylhä, A; Kleber, M; Laaksonen, R; Lääperi, M; Leiherer, A; Mader, A; März, W; Mündlein, A; Ramadani, H; Säly, CH; Vonbank, A | 1 |
| Chen, Y; Ding, L; Dong, P; Jiang, M; Shi, H; Wen, S; Yang, J; Yang, Y; Zhu, Y | 1 |
| Inuzuka, K; Iwaki, T; Sano, H; Sasaki, T; Setou, M; Suzuki, Y; Tanaka, H; Umemura, K; Unno, N; Urano, T; Yamamoto, N; Yata, T; Zaima, N | 1 |
| Vance, DE | 1 |
| Alonso, A; Huang, F; Li, D; Misialek, JR; Windham, GB; Yu, F | 1 |
| Gloor, GB; Joris, BR | 1 |
| Alonso, A; Gottesman, R; Jack, CR; Knopman, D; Li, D; Mielke, MM; Misialek, JR; Mosley, T | 1 |
| Arnebrant, T; Bengtsson, E; Cárdenas, M; Forsyth, VT; Fredrikson, GN; Haertlein, M; Lind, TK; Lund, R; Maric, S; Moulin, M; Pomorski, TG; Raida, MR; Rogers, S; Wenk, MR | 1 |
| Cenarro, A; Civeira, F; Cofán, M; Mateo-Gallego, R; Ros, E; Sala-Vila, A | 1 |
| Arduini, A; Lopaschuk, GD; Ussher, JR | 1 |
| Berliner, J; Cheng, J; Gugiu, BG; Jung, ME; Koroniak, L; Lee, S; Li, R; Yan, X | 1 |
| Hazen, SL; Tang, WH | 1 |
| Drosos, I; Kolios, G; Tavridou, A | 1 |
| Agardh, HE; Duhlin, A; Forsell, MN; Grasset, EK; Hägglöf, T; Hansson, GK; Karlsson, MC; Ketelhuth, DF; Ovchinnikova, O; Paulsson-Berne, G | 1 |
| Chen, YE; Freeman, L; Guo, Y; Killion, S; Morin, EE; Ossoli, A; Pryor, M; Remaley, AT; Schwendeman, A; Stonik, J; Sviridov, DO; Thacker, S; Turner, S; Yuan, W; Yuan, Y | 1 |
| Berliner, JA; Briot, A; Civelek, M; Fishbein, GA; Fishbein, MC; Fogelman, AM; Hoi, K; Hong, C; Iruela-Arispe, ML; Kim, J; Lee, SD; Lusis, AJ; Mack, JJ; Navab, M; Seki, A; Tontonoz, P; Vakili, L; Yu, J | 1 |
| Kato, S; Miyazawa, T; Nakagawa, K | 1 |
| Hennig, B; Hoffman, JB; Morris, AJ; Perkins, JT; Petriello, MC; Sunkara, M; Wahlang, B | 1 |
| Abramowicz, S; Chan, RB; Di Paolo, G; Hsieh, J; Hussain, MM; Ichi, I; Iqbal, J; Koseki, M; Lefkowitch, JH; Molusky, MM; Rader, DJ; Takiguchi, S; Tall, AR; Tascau, L; Welch, CL; Westerterp, M; Yakushiji, E; Yamashita, S | 1 |
| Aviram, M; Efrat, M; Mahmood, S; Rosenblat, M; Vaya, J | 1 |
| Kohlwein, SD; Malanovic, N; Rechberger, G; Streith, I; Tehlivets, O; Wolinski, H | 1 |
| Hara, S; Hatakeyama, S; Ikeda, K; Ishii, T; Ishikawa, Y; Isogai, Y; Itabe, H; Kato, R; Kobayashi, T; Kudo, I; Masuda, S; Murakami, M; Ohtsuki, M; Saka, G; Sato, H; Taguchi, R; Taketomi, Y; Tsutsumi, K; Yamada, J; Yamamoto, K | 1 |
| Basser, RL; Birjmohun, RS; Bisoendial, RJ; de Kort, H; Franssen, R; Kastelein, JJ; Kuivenhoven, JA; Levels, JH; Meijers, JC; Stroes, ES; van Leuven, SI | 1 |
| Boyanovsky, B; Forrest, K; Webb, NR; Zack, M | 1 |
| Brosnan, JT; Francis, GA; Jacobs, RL; Kennedy, B; Su, B; Vance, DE; Vance, JE; Waddington, E; Zhao, Y | 1 |
| Anantharamaiah, GM; Epand, RF; Epand, RM; Mishra, VK; Palgunachari, MN | 1 |
| Cooks, RG; Hendrickson, RC; Manicke, NE; Nefliu, M; Reiser, V; Woods, JW; Wu, C | 1 |
| Fujimoto, H; Kobayashi, H; Ohno, M | 1 |
| Berliner, JA; Chen, SS; Graeber, TG; Kafi, A; Komisopoulou, E; Martínez-Pinna, R; Titz, B; Zimman, A | 1 |
| Amar, MJ; D'Souza, W; Demosky, S; Hellerstein, M; Luchoomun, J; Remaley, AT; Stonik, J; Sviridov, D; Turner, S; Voogt, J | 1 |
| Sahebkar, A | 1 |
| Cole, LK; Dolinsky, VW; Dyck, JR; Vance, DE | 1 |
| Rader, DJ; Rak, K | 1 |
| Allayee, H; Bennett, BJ; Britt, EB; Chung, YM; DiDonato, JA; Dugar, B; Feldstein, AE; Fu, X; Hazen, SL; Klipfell, E; Koeth, R; Levison, BS; Lusis, AJ; Schauer, P; Smith, JD; Tang, WH; Wang, Z; Wu, Y | 1 |
| Cheng, XW; Enomoto, H; Goto-Inoue, N; Hayasaka, T; Kuzuya, M; Onoue, K; Sasaki, T; Setou, M; Tanaka, H; Unno, N; Zaima, N | 1 |
| Araujo, JA; Berliner, JA; Che, N; Civelek, M; Kayne, P; Lee, S; Lusis, AJ; Mai, N; Mungrue, IN; Pan, C; Pouldar, D; Romanoski, CE; Vakili, L; Yang, WP; Yin, F | 1 |
| Fingerle, J; Mary, JL; Ohnsorg, PM; Pech, M; Rohrer, L; von Eckardstein, A | 1 |
| Alique, M; Badimon, JJ; Badimon, L; Cimmino, G; Fuster, V; Giannarelli, C; Ibanez, B; Pinero, A; Santos-Gallego, CG; Vilahur, G | 1 |
| Anantharamaiah, GM; Deivanayagam, CCS; Garber, DW; Handattu, SP; McPherson, DT; Mishra, VK; Nayyar, G; Palgunachari, MN; Segrest, JP; Shin, R | 1 |
| André, P; Atout, R; Carreras, M; Dollet, S; Karabina, SA; Lambeau, G; Lotteau, V; Ninio, E; Payré, C; Perrin-Cocon, L | 1 |
| Aldover-Macasaet, E; Belgacem, O; Bicker, W; Bochkov, V; Pock, K; Sobal, G; Stübiger, G; Widhalm, K; Willfort-Ehringer, A | 1 |
| GREENBERG, DM; PILGERAM, LO | 1 |
| FISCHER, FW; KROETZ, C | 1 |
| KOZUBSKA-NIEBROJ, M; NIEBROJ, T; SAMOCHOWIEC, L | 1 |
| LOPUSHANSKII, VI | 1 |
| BILLIMORIA, JD; MACLAGAN, NF | 1 |
| DOVGIALLO, GK; GULKO, IS | 1 |
| OBERHOFFER, G; PUPITA, F; RAPPELLI, A; VACCARINO, A | 1 |
| PRESS, L | 1 |
| KONECKI, J; PIETKIEWICZ, W; SAMOCHOWIEC, L | 1 |
| KOSULINA, ON | 1 |
| Hirayama, Y; Kotake, H; Miyazawa, T; Oikawa, S; Sawai, T; Sekikawa, A; Tokita, Y; Toyota, T | 1 |
| Salomon, RG; Zhang, W | 1 |
| Dever, G; Spickett, CM | 1 |
| Berliner, JA; Cruz, D; Dun, M; Gharavi, N; Koroniak, L; Li, R; Montoya, D; Mouillesseaux, KP | 1 |
| Baker, NA; Berliner, JA; Gharavi, NM; Honda, HM; Hsieh, X; Mouillesseaux, KP; Smart, EJ; Yeh, M; Yeung, W | 1 |
| Leitinger, N | 1 |
| Pollock, JS; Sullivan, JC | 1 |
| Karabina, SA; Ninio, E | 1 |
| Baruch-Oren, T; Berliner, JA; Clark, MJ; Gargalovic, PS; Gharavi, NM; He, A; Kirchgessner, TG; Lusis, AJ; Pagnon, J; Truong, A; Yang, WP | 1 |
| Ramage, SC; Rufail, ML; van Antwerpen, R | 1 |
| Erridge, C; Spickett, CM; Webb, DJ | 1 |
| Bullitt, E; Gantz, D; Jiang, ZG; McKnight, CJ | 1 |
| Esterbauer, H; Exner, M; Gmeiner, BM; Holzer, G; Kapiotis, S; Kopp, CW; Kronke, G; Leitinger, N; Wagner, O | 1 |
| Kawamura, A; Matsuo, Y; Miura, S; Rye, KA; Saku, K; Uehara, Y | 1 |
| Araujo, JA; Berliner, JA; Chang, I; Clark, MJ; Gargalovic, PS; Gharavi, NM; Lusis, AJ; Szeto, WL; Watson, AD | 1 |
| Cohen, DE; Kanno, K; Roderick, SL; Scapa, EF; Wu, MK | 1 |
| Bezouglaia, O; Demer, LL; Huang, MS; Lu, J; Morony, S; Tetradis, S; Tintut, Y; Tseng, W; Zhang, Z | 1 |
| Araujo, JA; Barajas, B; Gong, KW; Horvath, S; Kleinman, M; Li, N; Lusis, AJ; Nel, A; Sioutas, C; Zhao, W | 1 |
| Alva, JA; Berliner, JA; Fishbein, M; Gharavi, NM; Hong, L; Johnson, J; Lai, C; Mouillesseaux, KP; Pfeffer, LM; Szeto, WL; Wei, L; Yeh, M; Yeung, W | 1 |
| Benson, R; Dever, GJ; Kennedy, S; Spickett, CM; Wainwright, CL | 1 |
| Duong, V; Gugiu, BG; Hekimian, A; Herzog, T; Koroniak, L; Mouillesseaux, K; Vondriska, TM; Watson, AD | 1 |
| Burnand, KG; Davis, B; Douet, LJ; Humphries, J; Koster, G; Macphee, CH; Postle, AD; Scigelova, M; Smith, A; Ward, JM; Woffendin, G | 1 |
| Balconi, E; Bisgaier, CL; Castano, M; Chaabane, L; Chiesa, G; Krause, B; Lorenzon, P; Lorusso, V; Marchesi, M; Martin, BJ; Miragoli, L; Morisetti, A; Newton, RS; Parolini, C; Sirtori, CR | 1 |
| Badimon, JJ; Badimon, L; Choi, BG; Cimmino, G; Fuster, V; Ibanez, B; Krause, B; Pinero, A; Santos-Gallego, CG; Speidl, WS; Vilahur, G; Zafar, MU | 1 |
| Aceves, M; Crespo, MS; Dueñas, AI; Fernández-Pisonero, I; García-Rodríguez, C; Gómez, C; Orduña, A | 1 |
12 review(s) available for phosphatidylcholines and Atherosclerosis
| Article | Year |
|---|---|
Roles of Reconstituted High-Density Lipoprotein Nanoparticles in Cardiovascular Disease: A New Paradigm for Drug Discovery.
Topics: Animals; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; Biomimetics; Drug Discovery; Humans; Lipoproteins, HDL; Macrophages; Mice; Molecular Imaging; Nanoparticles; Phosphatidylcholines | 2020 |
The mechanisms of lysophosphatidylcholine in the development of diseases.
Topics: Animals; Arteries; Atherosclerosis; Blood Glucose; Cardiovascular Diseases; Cell Movement; Cytokines; Endothelial Cells; Humans; Inflammation; Insulin Resistance; Lipoproteins, LDL; Lymphocytes; Lysophosphatidylcholines; Macrophages; Myocytes, Smooth Muscle; Neoplasms; Nervous System Diseases; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A2; Pyroptosis; Receptors, G-Protein-Coupled; Toll-Like Receptors | 2020 |
Sulfur-Containing Amino Acids and Lipid Metabolism.
Topics: Amino Acids, Sulfur; Animals; Atherosclerosis; Betaine; Cholesterol; Cysteine; Dietary Proteins; Dietary Supplements; Fatty Liver; Glutathione; Humans; Hydrogen Sulfide; Hyperhomocysteinemia; Lipid Metabolism; Methionine; Nutritional Requirements; Nutritional Status; Phosphatidylcholines; Sulfur; Sulfur Compounds; Taurine | 2020 |
Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Carnitine; Choline; Energy Metabolism; Fatty Acids, Volatile; Gastrointestinal Microbiome; Genomics; High-Throughput Nucleotide Sequencing; Humans; Lipid Metabolism; Metabolic Syndrome; Methylamines; Phosphatidylcholines; RNA, Ribosomal, 16S; T-Lymphocytes, Helper-Inducer; Triglycerides | 2019 |
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Insulin Resistance; Intestines; Liver; Methylamines; Mice; Microbiota; Muscle, Skeletal; Myocardial Ischemia; Phosphatidylcholines; Risk | 2013 |
The contributory role of gut microbiota in cardiovascular disease.
Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines | 2014 |
New aspects on the metabolic role of intestinal microbiota in the development of atherosclerosis.
Topics: Animals; Atherosclerosis; Betaine; Carnitine; Choline; Humans; Intestinal Mucosa; Intestines; Methylamines; Microbiota; Phosphatidylcholines | 2015 |
Determination of Phosphatidylcholine Hydroperoxide (PCOOH) as a Marker of Membrane Lipid Peroxidation.
Topics: Atherosclerosis; Biomarkers; Chromatography, High Pressure Liquid; Humans; Isomerism; Linoleic Acids; Lipid Peroxidation; Lipid Peroxides; Oxidative Stress; Phosphatidylcholines; Tandem Mass Spectrometry | 2015 |
BIOCHEMISTRY OF ATHEROSCLEROSIS.
Topics: Arteriosclerosis; Atherosclerosis; Blood Coagulation Tests; Dietary Fats; Fatty Acids; Fibrinolysis; Humans; Lecithins; Lipids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids | 1963 |
Oxidized phospholipids, isolevuglandins, and atherosclerosis.
Topics: Aldehydes; Animals; Atherosclerosis; Blood Proteins; Cross-Linking Reagents; Fatty Acids, Unsaturated; Free Radicals; Humans; Lipid Peroxidation; Lipoproteins, LDL; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Phospholipids; Platelet Activation; Prostaglandins; Protein Binding; Risk Factors | 2005 |
Plasma PAF-acetylhydrolase: an unfulfilled promise?
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Animals; Anti-Inflammatory Agents; Asthma; Atherosclerosis; Biomarkers; Disease Models, Animal; Humans; Inflammation; Lipoproteins, LDL; Macrophages; Oxidation-Reduction; Phosphatidylcholines; Platelet Activating Factor; Recombinant Proteins; Sepsis | 2006 |
Structure and function of phosphatidylcholine transfer protein (PC-TP)/StarD2.
Topics: Animals; Atherosclerosis; Bile Acids and Salts; Biological Transport; Cattle; Lipoproteins, HDL; Liver; Mice; Mice, Knockout; Models, Molecular; Molecular Structure; Phosphatidylcholines; Phospholipid Transfer Proteins; Protein Structure, Tertiary; Pulmonary Surfactants; Species Specificity; Tissue Distribution | 2007 |
1 trial(s) available for phosphatidylcholines and Atherosclerosis
| Article | Year |
|---|---|
The dietary soy flavonoid genistein abrogates tissue factor induction in endothelial cells induced by the atherogenic oxidized phospholipid oxPAPC.
Topics: Anticoagulants; Atherosclerosis; Cell Culture Techniques; Endothelial Cells; Genistein; Humans; Phosphatidylcholines; Thromboplastin | 2007 |
74 other study(ies) available for phosphatidylcholines and Atherosclerosis
| Article | Year |
|---|---|
Elucidation of physico-chemical principles of high-density lipoprotein-small RNA binding interactions.
Topics: Animals; Apolipoprotein A-I; Atherosclerosis; Humans; Lipoproteins, HDL; Mice; Phosphatidylcholines; RNA, Small Untranslated | 2022 |
Multi-technique comparison of atherogenic and MCD NASH models highlights changes in sphingolipid metabolism.
Topics: Animals; Atherosclerosis; Choline; Diet; Diet, Atherogenic; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Lipidomics; Male; Methionine; Mice; Non-alcoholic Fatty Liver Disease; Phosphatidylcholines; Sphingolipids | 2019 |
NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli.
Topics: Atherosclerosis; Cells, Cultured; Cellular Senescence; Databases, Genetic; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Human Umbilical Vein Endothelial Cells; Humans; MicroRNAs; NF-E2-Related Factor 2; Oxidation-Reduction; Phosphatidylcholines; Plaque, Atherosclerotic; Transcriptome | 2021 |
Effect of Phosphatidylcholine Nanosomes on Phospholipid Composition of the Plasma Membranes in Liver Cells and Blood Serum in Experimental Atherosclerosis.
Topics: Animals; Antioxidants; Atherosclerosis; Cardiolipins; Cell Membrane; Diet, Atherogenic; Immune System; Lipoproteins; Liver; Lysophosphatidylcholines; Nanoparticles; Phosphatidylcholines; Phospholipids; Rabbits; Risk Factors; Thrombosis | 2020 |
Early Signs of Atherogenic Features in the HDL Lipidomes of Normolipidemic Patients Newly Diagnosed with Type 2 Diabetes.
Topics: Aged; Atherosclerosis; Cholesterol, HDL; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Acids; Female; Humans; Lipidomics; Lipoproteins, HDL; Lysophosphatidylcholines; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Phosphatidylethanolamines; Sphingomyelins; Triglycerides | 2020 |
Dietary phosphatidylcholine supplementation reduces atherosclerosis in Ldlr
Topics: Animals; Atherosclerosis; Diet, High-Fat; Dietary Supplements; Gene Deletion; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Receptors, LDL | 2021 |
Lipidomics Approach in High-Fat-Diet-Induced Atherosclerosis Dyslipidemia Hamsters: Alleviation Using Ether-Phospholipids in Sea Urchin.
Topics: Animals; Atherosclerosis; Cricetinae; Diet, High-Fat; Dyslipidemias; Lipidomics; Phosphatidylcholines; Phospholipid Ethers; Sea Urchins | 2021 |
Gut microbiota-generated metabolite, trimethylamine-N-oxide, and subclinical myocardial damage: a multicenter study from Thailand.
Topics: Aged; Aged, 80 and over; Atherosclerosis; Cardiovascular Diseases; Case-Control Studies; Female; Gastrointestinal Microbiome; Humans; Male; Methylamines; Middle Aged; Phosphatidylcholines; Risk Assessment; Thailand; Troponin T | 2021 |
Lipid profiles of patients with manifest coronary versus peripheral atherosclerosis - Is there a difference?
Topics: Atherosclerosis; Ceramides; Coronary Artery Disease; Diabetes Mellitus, Type 2; Humans; Lipids; Lipoproteins; Peripheral Arterial Disease; Phosphatidylcholines; Risk Factors | 2021 |
Atherosclerotic dyslipidemia revealed by plasma lipidomics on ApoE
Topics: Animals; Atherosclerosis; Biomarkers; Chromatography, High Pressure Liquid; Diet, High-Fat; Discriminant Analysis; Disease Models, Animal; Disease Progression; Dyslipidemias; Genetic Predisposition to Disease; Lipids; Male; Mass Spectrometry; Metabolomics; Mice, Inbred C57BL; Mice, Knockout, ApoE; Pattern Recognition, Automated; Phenotype; Phosphatidylcholines; Plaque, Atherosclerotic; Sphingomyelins; Sphingosine | 2017 |
Lysophosphatidylcholine Acyltransferase-3 Expression Is Associated with Atherosclerosis Progression.
Topics: 1-Acylglycerophosphocholine O-Acyltransferase; Aged; Aged, 80 and over; Animals; Apolipoproteins E; Arachidonic Acid; Arteries; Atherosclerosis; Disease Models, Animal; Disease Progression; Female; Humans; Lysophosphatidylcholines; Male; Mice, Inbred BALB C; Mice, Knockout; Middle Aged; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylcholines; Plaque, Atherosclerotic; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation | 2017 |
From masochistic enzymology to mechanistic physiology and disease.
Topics: Animals; Atherosclerosis; Choline-Phosphate Cytidylyltransferase; Diet; Embryo, Mammalian; Gene Targeting; History, 20th Century; History, 21st Century; Humans; Insulin Resistance; Mice; Mice, Knockout; Obesity; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase | 2017 |
Independent Association of Plasma Hydroxysphingomyelins With Physical Function in the Atherosclerosis Risk in Communities (ARIC) Study.
Topics: Aged; Arginine; Atherosclerosis; Cross-Sectional Studies; Female; Hand Strength; Humans; Linear Models; Male; Phosphatidylcholines; Physical Fitness; Risk Factors; Sphingomyelins; Walking Speed | 2018 |
Plasma Metabolites Associated with Brain MRI Measures of Neurodegeneration in Older Adults in the Atherosclerosis Risk in Communities⁻Neurocognitive Study (ARIC-NCS).
Topics: Aged; Aged, 80 and over; Atherosclerosis; Brain; Female; Humans; Linear Models; Magnetic Resonance Imaging; Male; Neurodegenerative Diseases; Phosphatidylcholines; Prospective Studies; Risk Assessment; Sphingomyelins | 2019 |
Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes.
Topics: Atherosclerosis; Cell Membrane; Cholesterol; Humans; Lipids; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Membranes; Neutrons; Phosphatidylcholines; Scattering, Small Angle | 2019 |
Eicosapentaenoic acid in serum phospholipids relates to a less atherogenic lipoprotein profile in subjects with familial hypercholesterolemia.
Topics: Adult; Alcohol Drinking; Animals; Atherosclerosis; Biomarkers; Cross-Sectional Studies; Docosahexaenoic Acids; Eicosapentaenoic Acid; Fasting; Female; Fishes; Humans; Hyperlipoproteinemia Type II; Lipoproteins, HDL; Lipoproteins, LDL; Magnetic Resonance Spectroscopy; Male; Middle Aged; Phosphatidylcholines; Phospholipids; Risk Factors; Surveys and Questionnaires; Triglycerides | 2013 |
Fatty acid epoxyisoprostane E2 stimulates an oxidative stress response in endothelial cells.
Topics: Apoptosis Regulatory Proteins; Atherosclerosis; Cells, Cultured; Endothelial Cells; Heme Oxygenase-1; Humans; Isoprostanes; NF-E2-Related Factor 2; Oxidative Stress; Phosphatidylcholines; Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation | 2014 |
Sterile inflammation in the spleen during atherosclerosis provides oxidation-specific epitopes that induce a protective B-cell response.
Topics: Aging; Animals; Apolipoproteins E; Apoptosis; Atherosclerosis; B-Lymphocytes; Cholesterol; Clone Cells; Epitopes; Germinal Center; Inflammasomes; Inflammation; Lipoproteins, LDL; Lymphocyte Activation; Mice, Inbred C57BL; Oxidation-Reduction; Phosphatidylcholines; Spleen | 2015 |
The effect of phospholipid composition of reconstituted HDL on its cholesterol efflux and anti-inflammatory properties.
Topics: Animals; Apolipoprotein A-I; Atherosclerosis; Cholesterol; Humans; Inflammation; Lipoproteins, HDL; Mice; Peptides; Phosphatidylcholines; Phospholipids; Rats; Sphingomyelins | 2015 |
Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.
Topics: Adult; Animals; Atherosclerosis; Cell Line, Tumor; Cells, Cultured; Diet, High-Fat; Endothelial Cells; Female; Humans; Inflammation; Interleukin-1beta; Lipids; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Oligonucleotide Array Sequence Analysis; Phosphatidylcholines; Receptor, Notch1; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcriptome; Tumor Necrosis Factor-alpha | 2015 |
Dioxin-like pollutants increase hepatic flavin containing monooxygenase (FMO3) expression to promote synthesis of the pro-atherogenic nutrient biomarker trimethylamine N-oxide from dietary precursors.
Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Choline; Deuterium; Dietary Fats; Environmental Pollutants; Enzyme Induction; Food-Drug Interactions; Liver; Male; Methylamines; Mice, Inbred C57BL; Oxygenases; Phosphatidylcholines; Polychlorinated Biphenyls; Random Allocation; Up-Regulation | 2016 |
TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Cassette Transporter, Subfamily G, Member 8; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholesterol, Dietary; Cholesterol, HDL; Diet, High-Fat; Fatty Acids, Unsaturated; Fatty Liver; Female; Gene Expression Regulation; Hepatocytes; Ligands; Lipogenesis; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Liver X Receptors; Male; Mice; Orphan Nuclear Receptors; Phosphatidylcholines; Protein Stability; Proteolysis; Receptors, LDL; Sterol Regulatory Element Binding Protein 1; Ubiquitination | 2016 |
Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies.
Topics: Animals; Aryldialkylphosphatase; Atherosclerosis; Catalysis; Cell Line; Cholesterol, HDL; Dietary Fats; Enzyme Activation; Fatty Acids; In Vitro Techniques; Macrophages; Mice; Mice, Inbred BALB C; Olive Oil; Phosphatidylcholines; Plant Oils | 2009 |
S-adenosyl-L-homocysteine hydrolase, key enzyme of methylation metabolism, regulates phosphatidylcholine synthesis and triacylglycerol homeostasis in yeast: implications for homocysteine as a risk factor of atherosclerosis.
Topics: Adenosylhomocysteinase; Atherosclerosis; Down-Regulation; Endoplasmic Reticulum; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Homeostasis; Homocysteine; Humans; Membrane Proteins; Methylation; Myo-Inositol-1-Phosphate Synthase; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Repressor Proteins; Risk Factors; S-Adenosylhomocysteine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Triglycerides | 2008 |
Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Bee Venoms; Diet, Atherogenic; Foam Cells; Group III Phospholipases A2; Isoenzymes; Lipoproteins, HDL; Lipoproteins, LDL; Lysophosphatidylcholines; Mice; Mice, Transgenic; Phosphatidylcholines; Protein Processing, Post-Translational; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity | 2008 |
ApoAI-phosphatidylcholine infusion neutralizes the atherothrombotic effects of C-reactive protein in humans.
Topics: Adult; Apolipoprotein A-I; Atherosclerosis; C-Reactive Protein; Endothelial Cells; Humans; Inflammation; Male; Middle Aged; Phosphatidylcholines; Recombinant Proteins; Thrombosis | 2009 |
The capacity of group V sPLA2 to increase atherogenicity of ApoE-/- and LDLR-/- mouse LDL in vitro predicts its atherogenic role in vivo.
Topics: Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cells, Cultured; Collagen; Dietary Fats; Disease Models, Animal; Female; Foam Cells; Group V Phospholipases A2; Hydrolysis; Lipoproteins, LDL; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Receptors, LDL; Sphingomyelins; Time Factors | 2009 |
Lack of phosphatidylethanolamine N-methyltransferase alters plasma VLDL phospholipids and attenuates atherosclerosis in mice.
Topics: Animals; Apolipoproteins B; Atherosclerosis; Cholesterol; Cholesterol Esters; Disease Models, Animal; Female; Homocysteine; Kinetics; Lipoproteins, IDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Receptors, LDL; Triglycerides | 2009 |
Anti-inflammatory peptides grab on to the whiskers of atherogenic oxidized lipids.
Topics: Anti-Inflammatory Agents; Atherosclerosis; Calorimetry, Differential Scanning; Lipid Bilayers; Lipids; Oxidation-Reduction; Peptides; Phosphatidylcholines; Phospholipid Ethers; Phosphorylcholine | 2009 |
Imaging of lipids in atheroma by desorption electrospray ionization mass spectrometry.
Topics: Atherosclerosis; Betaine; Cholesterol; Humans; Phosphatidylcholines; Phospholipids; Spectrometry, Mass, Electrospray Ionization; Sphingomyelins | 2009 |
Age-induced reduction in mitochondrial manganese superoxide dismutase activity and tolerance of macrophages against apoptosis induced by oxidized low density lipoprotein.
Topics: Adult; Aging; Apoptosis; Atherosclerosis; Cells, Cultured; Down-Regulation; Female; Genotype; Humans; Leukocytes; Lipoproteins, LDL; Macrophages; Male; Middle Aged; Mitochondria; Oxidative Stress; Phenotype; Phosphatidylcholines; Superoxide Dismutase; Young Adult | 2010 |
Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis.
Topics: Amino Acid Sequence; Animals; Aorta; Atherosclerosis; Cardiac Myosins; Cattle; Cells, Cultured; Chromatography, Ion Exchange; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Molecular Sequence Data; Myosin Light Chains; Peptide Fragments; Phosphatidylcholines; Phosphoproteins; Phosphorylation; Proteome; Proteomics; Receptor, TIE-1; Reproducibility of Results; Signal Transduction | 2010 |
5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice.
Topics: Animals; Aorta; Apolipoprotein A-I; Apolipoproteins E; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cholesterol; Female; Humans; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Peptides; Phosphatidylcholines; Rats; Rats, Sprague-Dawley | 2010 |
Phosphatidylcholine-rich nanoliposomes: potential tools for serum C-reactive protein reduction?
Topics: Atherosclerosis; C-Reactive Protein; Humans; Liposomes; Nanoparticles; Phosphatidylcholines | 2011 |
Impaired phosphatidylcholine biosynthesis reduces atherosclerosis and prevents lipotoxic cardiac dysfunction in ApoE-/- Mice.
Topics: Aging; Animals; Aorta; Apolipoproteins E; Atherosclerosis; Cholesterol; Heart; Heart Diseases; Lipid Metabolism; Lipoproteins; Liver; Mice; Mice, Knockout; Myocardium; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Triglycerides | 2011 |
Cardiovascular disease: the diet-microbe morbid union.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Choline; Diet; Dietary Fats; Gastrointestinal Tract; Humans; Liver; Metabolomics; Methylamines; Mice; Oxygenases; Phosphatidylcholines; Probiotics; Risk Assessment | 2011 |
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease.
Topics: Animals; Atherosclerosis; Betaine; Biomarkers; Cardiovascular Diseases; Cholesterol, HDL; Choline; Diet; Dietary Fats; Female; Gastrointestinal Tract; Gene Expression Regulation; Germ-Free Life; Humans; Liver; Macrophages; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Oxygenases; Phenotype; Phosphatidylcholines; Receptors, Scavenger; Risk Assessment | 2011 |
Imaging mass spectrometry-based histopathologic examination of atherosclerotic lesions.
Topics: Animals; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Calcinosis; Cholesterol Esters; Disease Models, Animal; Humans; Linoleic Acids; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Peripheral Arterial Disease; Phosphatidylcholines; Predictive Value of Tests; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triglycerides | 2011 |
Network for activation of human endothelial cells by oxidized phospholipids: a critical role of heme oxygenase 1.
Topics: Adult; Atherosclerosis; Cells, Cultured; Endothelium, Vascular; Gene Expression Profiling; Gene Regulatory Networks; Heme Oxygenase-1; Humans; Phosphatidylcholines | 2011 |
Trimerized apolipoprotein A-I (TripA) forms lipoproteins, activates lecithin: cholesterol acyltransferase, elicits lipid efflux, and is transported through aortic endothelial cells.
Topics: Animals; Aorta; Apolipoprotein A-I; Atherosclerosis; ATP-Binding Cassette Transporters; Cardiovascular Agents; Cattle; Coronary Disease; Endothelial Cells; Gene Silencing; Humans; Kinetics; Lipoproteins, HDL; Phosphatidylcholine-Sterol O-Acyltransferase; Phosphatidylcholines; Protein Binding; Protein Transport; Recombinant Proteins; RNA, Small Interfering | 2011 |
Recombinant HDL(Milano) exerts greater anti-inflammatory and plaque stabilizing properties than HDL(wild-type).
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Aorta, Abdominal; Aortic Diseases; Apolipoprotein A-I; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Caspase 3; CD36 Antigens; Cell Line; Chemokine CCL2; Cholesterol; Cyclooxygenase 2; Disease Models, Animal; Infusions, Intravenous; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Macrophages; Magnetic Resonance Imaging; Matrix Metalloproteinase 2; Oxidative Stress; Phosphatidylcholines; Rabbits; Recombinant Proteins; Time Factors | 2012 |
Sidedness of interfacial arginine residues and anti-atherogenicity of apolipoprotein A-I mimetic peptides.
Topics: Animals; Apolipoprotein A-I; Arginine; Aryldialkylphosphatase; Atherosclerosis; Chemical Phenomena; Cholesterol; Female; Gene Deletion; Guanidine; Humans; Lipoproteins, HDL; Mice; Oxidation-Reduction; Peptidomimetics; Phosphatidylcholines; Protein Structure, Secondary; Protein Unfolding; Reactive Oxygen Species; Unilamellar Liposomes | 2012 |
Human group X secreted phospholipase A2 induces dendritic cell maturation through lipoprotein-dependent and -independent mechanisms.
Topics: Atherosclerosis; Coculture Techniques; Dendritic Cells; Fatty Acids, Nonesterified; Group X Phospholipases A2; Humans; Hydrolysis; Interferon-gamma; Lipoproteins, LDL; Lysophosphatidylcholines; Phenotype; Phosphatidylcholines; Th1 Cells | 2012 |
Targeted profiling of atherogenic phospholipids in human plasma and lipoproteins of hyperlipidemic patients using MALDI-QIT-TOF-MS/MS.
Topics: Adolescent; Atherosclerosis; Biomarkers; Child; Cholesterol, LDL; Female; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Lipoproteins; Lysophosphatidylcholines; Male; Phosphatidylcholines; Phospholipids; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sphingomyelins; Tandem Mass Spectrometry; Young Adult | 2012 |
Susceptibility to experimental atherosclerosis and the methylation of ethanolamine 1,2-C14 to phosphatidyl choline.
Topics: Amino Alcohols; Arteriosclerosis; Atherosclerosis; Choline; Disease Susceptibility; Ethanolamine; Ethanolamines; Methylation; Phosphatidylcholines | 1954 |
[Beta-Lipoproteins & their relation to age groups, to stages of progressive atherosclerosis & to various eye diseases].
Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Eye Diseases; Humans; Lecithins; Lipoproteins; Lipoproteins, LDL; Phosphatidylcholines; Vascular Diseases | 1957 |
[The effect of "essential" phospholipids on the histochemistry of the adrenal cortex during experimental atherosclerosis in rats].
Topics: Adrenal Cortex; Animals; Arteriosclerosis; Atherosclerosis; Phosphatidylcholines; Phospholipids; Rats | 1962 |
[APPLICATION OF VITAMIN B1 AND B12 IN PATIENTS WITH ATHEROSCLEROSIS].
Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Corrinoids; Hematinics; Humans; Lecithins; Phosphatidylcholines; Thiamine; Vitamin B 12 | 1963 |
[USE OF NICOTINIC ACID IN ATHEROSCLEROSIS].
Topics: Arteriosclerosis; Atherosclerosis; Blood Protein Electrophoresis; Cholesterol; Lecithins; Niacin; Nicotinic Acids; Pharmacology; Phosphatidylcholines | 1963 |
[CONTRIBUTION TO THE STUDY OF THE THERAPY OF ATHEROSCLEROSIS WITH ESSENTIAL PHOSPHOLIPIDS].
Topics: Arteriosclerosis; Atherosclerosis; Blood Proteins; Cholesterol; Coronary Disease; Lipids; Lipoproteins; Phosphatidylcholines; Phospholipids | 1964 |
[ATHEROSCLEROSIS AND PLASMATIC ATHEROGENIC INDICES].
Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Humans; Lecithins; Lipids; Lipoproteins; Phosphatidylcholines; Phospholipids | 1964 |
[Parenteral administration of "essential" phospholipids in experimental atherosclerosis in rats].
Topics: Animals; Arteriosclerosis; Atherosclerosis; Phosphatidylcholines; Phospholipids; Rats | 1962 |
[Effect of soy lecithin and a low cholesterol diet on the course of atherosclerosis].
Topics: Arteriosclerosis; Atherosclerosis; Cholesterol; Diet; Glycine max; Humans; Lecithins; Nutrition Assessment; Phosphatidylcholines | 1962 |
Fructose ingestion enhances atherosclerosis and deposition of advanced glycated end-products in cholesterol-fed rabbits.
Topics: Animals; Atherosclerosis; Cholesterol; Fructose; Glycation End Products, Advanced; Hyperlipidemias; Lipid Peroxidation; Male; Oxidative Stress; Phosphatidylcholines; Rabbits | 2005 |
Studies of phospholipid oxidation by electrospray mass spectrometry: from analysis in cells to biological effects.
Topics: Animals; Atherosclerosis; Chlorohydrins; Chromatography, Liquid; Erythrocytes; Fatty Acids; Humans; Hypochlorous Acid; Lipid Peroxidation; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Oxidative Stress; Phosphatidylcholines; Phospholipids; Rabbits; Spectrometry, Mass, Electrospray Ionization | 2005 |
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC.
Topics: Alprostadil; Atherosclerosis; Cells, Cultured; Dinoprostone; Foam Cells; Humans; Interleukin-10; Isoprostanes; Macrophages; Monocytes; Oxidation-Reduction; Phosphatidylcholines; Phospholipid Ethers; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthones | 2006 |
Role of endothelial nitric oxide synthase in the regulation of SREBP activation by oxidized phospholipids.
Topics: Animals; Atherosclerosis; Cattle; Cells, Cultured; CSK Tyrosine-Protein Kinase; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Humans; Interleukin-8; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oxidation-Reduction; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phospholipid Ethers; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; src-Family Kinases; Sterol Regulatory Element Binding Proteins; Superoxides | 2006 |
A rancid culprit in vascular inflammation acts on the prostaglandin receptor EP2.
Topics: Atherosclerosis; Cyclic AMP; Dinoprostone; Humans; Isoprostanes; Oxidation-Reduction; Phosphatidylcholines; Phospholipases A; Phospholipid Ethers; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP2 Subtype | 2006 |
Coupled and uncoupled NOS: separate but equal? Uncoupled NOS in endothelial cells is a critical pathway for intracellular signaling.
Topics: Animals; Atherosclerosis; Endothelial Cells; Humans; Interleukin-8; Mice; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylcholines; Phosphorylation; Signal Transduction; Sterol Regulatory Element Binding Proteins; Superoxides | 2006 |
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells.
Topics: Activating Transcription Factor 4; Aorta; Atherosclerosis; Cells, Cultured; Chromosome Mapping; DNA-Binding Proteins; Endothelial Cells; Gene Expression; Gene Expression Regulation; Humans; Immunologic Techniques; Inflammation; Nuclear Proteins; Oxidation-Reduction; Phosphatidylcholines; Phospholipids; Protein Folding; Regulatory Factor X Transcription Factors; Tissue Distribution; Transcription Factors; X-Box Binding Protein 1 | 2006 |
C-reactive protein inhibits in vitro oxidation of low-density lipoprotein.
Topics: Antibodies, Monoclonal; Atherosclerosis; C-Reactive Protein; Copper; Humans; Lipoproteins, LDL; Liposomes; Oxidation-Reduction; Phosphatidylcholines | 2006 |
Toll-like receptor 4 signalling is neither sufficient nor required for oxidised phospholipid mediated induction of interleukin-8 expression.
Topics: Atherosclerosis; Base Sequence; Cell Line; Cells, Cultured; DNA Primers; Endothelial Cells; Gene Expression; Humans; Interleukin-8; Lipids; NF-kappa B; Phosphatidylcholines; Promoter Regions, Genetic; Recombinant Proteins; Signal Transduction; Toll-Like Receptor 4; Transfection | 2007 |
Defining lipid-interacting domains in the N-terminal region of apolipoprotein B.
Topics: Apolipoproteins B; Atherosclerosis; Carrier Proteins; Chylomicrons; Egg Proteins; Egg Proteins, Dietary; Endoplasmic Reticulum; Humans; Kinetics; Lipoproteins, VLDL; Models, Molecular; Phosphatidylcholines; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary | 2006 |
Newly developed reconstituted high-density lipoprotein containing sphingosine-1-phosphate induces endothelial tube formation.
Topics: Animals; Atherosclerosis; Cell Division; Cells, Cultured; CHO Cells; Cholesterol; Coronary Vessels; Cricetinae; Cricetulus; Endothelial Cells; Enzyme Inhibitors; Humans; In Vitro Techniques; Lipoproteins, HDL; Lysophospholipids; Macrophages; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type III; Oligonucleotides, Antisense; Phosphatidylcholines; Proto-Oncogene Proteins c-akt; ras Proteins; Sphingosine | 2007 |
High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory.
Topics: Anti-Inflammatory Agents; Antioxidants; Aorta; Atherosclerosis; Cell Adhesion; Cells, Cultured; Chemotaxis; CSK Tyrosine-Protein Kinase; Cytokines; Endothelial Cells; Gene Expression; Humans; Inflammation; Isoprostanes; Lipid Metabolism; Lipoproteins, HDL; Monocytes; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphatidylcholines; Phosphorylation; Protein-Tyrosine Kinases; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; src-Family Kinases; STAT3 Transcription Factor; Sterol Regulatory Element Binding Proteins; Sterols; Transcription Factors | 2007 |
Atherogenic phospholipids attenuate osteogenic signaling by BMP-2 and parathyroid hormone in osteoblasts.
Topics: Animals; Atherosclerosis; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Mice; Nuclear Receptor Subfamily 4, Group A, Member 2; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Parathyroid Hormone; Phosphatidylcholines; Phospholipids; Phosphorylcholine; Signal Transduction; Transcription Factors; Transforming Growth Factor beta | 2007 |
Air-pollutant chemicals and oxidized lipids exhibit genome-wide synergistic effects on endothelial cells.
Topics: Air Pollutants; Atherosclerosis; Cell Line; Endothelium, Vascular; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Genome, Human; Heme Oxygenase-1; Humans; Phosphatidylcholines; Vasculitis; Vehicle Emissions | 2007 |
Role of the Jak/STAT pathway in the regulation of interleukin-8 transcription by oxidized phospholipids in vitro and in atherosclerosis in vivo.
Topics: Animals; Aorta; Atherosclerosis; Capillaries; Cells, Cultured; Chromatin Immunoprecipitation; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Humans; Immunohistochemistry; In Vitro Techniques; Interleukin-8; Janus Kinase 2; Mice; Mice, Knockout; Models, Biological; Oxidation-Reduction; Phosphatidylcholines; Phosphorylation; Plasmids; RNA, Small Interfering; STAT3 Transcription Factor; Time Factors; Trans-Activators; Transcription, Genetic; Transfection | 2007 |
Phospholipid chlorohydrin induces leukocyte adhesion to ApoE-/- mouse arteries via upregulation of P-selectin.
Topics: Animals; Anticholesteremic Agents; Apolipoproteins E; Arteries; Atherosclerosis; Cell Adhesion; Chlorohydrins; Hypochlorous Acid; Inflammation; Intercellular Adhesion Molecule-1; Leukocytes; Lipoproteins, LDL; Mice; Mice, Knockout; Nitrates; P-Selectin; Phosphatidylcholines; Phospholipids; Pravastatin; Reactive Oxygen Species; Up-Regulation | 2008 |
Protein targets of oxidized phospholipids in endothelial cells.
Topics: Atherosclerosis; Biotinylation; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Humans; Inflammation; Lipid Peroxidation; Phosphatidylcholines; Phospholipids; Protein Binding; Proteins | 2008 |
Electrospray ionization mass spectrometry identifies substrates and products of lipoprotein-associated phospholipase A2 in oxidized human low density lipoprotein.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Atherosclerosis; Biomarkers; Enzyme Inhibitors; Fatty Acids; Humans; Inflammation; Lipoproteins, LDL; Lysophospholipids; Oxidation-Reduction; Phosphatidylcholines; Spectrometry, Mass, Electrospray Ionization | 2008 |
Dose-related effects of repeated ETC-216 (recombinant apolipoprotein A-I Milano/1-palmitoyl-2-oleoyl phosphatidylcholine complexes) administrations on rabbit lipid-rich soft plaques: in vivo assessment by intravascular ultrasound and magnetic resonance im
Topics: Animals; Anticholesteremic Agents; Apolipoprotein A-I; Atherosclerosis; Carotid Artery, Common; Carotid Stenosis; Cholesterol, HDL; Disease Models, Animal; Dose-Response Relationship, Drug; Magnetic Resonance Imaging; Male; Phosphatidylcholines; Rabbits; Random Allocation; Ultrasonography | 2008 |
Rapid change in plaque size, composition, and molecular footprint after recombinant apolipoprotein A-I Milano (ETC-216) administration: magnetic resonance imaging study in an experimental model of atherosclerosis.
Topics: Animals; Anticholesteremic Agents; Aortic Diseases; Apolipoprotein A-I; Atherosclerosis; Disease Models, Animal; Gene Expression; Male; Phosphatidylcholines; Rabbits; Random Allocation | 2008 |
Selective attenuation of Toll-like receptor 2 signalling may explain the atheroprotective effect of sphingosine 1-phosphate.
Topics: Atherosclerosis; Cell Line; Chemokines; Enzyme Inhibitors; Humans; Lipoproteins, HDL; Lipoproteins, LDL; Lysophospholipids; NF-kappa B; Phagocytes; Phosphatidylcholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; ras Proteins; Receptors, Lysosphingolipid; RNA Interference; RNA, Small Interfering; Signal Transduction; Sphingosine; Time Factors; Toll-Like Receptor 2; Transcription, Genetic; Transfection | 2008 |