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phosphatidylcholines and Acute Liver Injury, Drug-Induced

phosphatidylcholines has been researched along with Acute Liver Injury, Drug-Induced in 71 studies

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	27 (38.03)	18.7374
1990's	12 (16.90)	18.2507
2000's	11 (15.49)	29.6817
2010's	17 (23.94)	24.3611
2020's	4 (5.63)	2.80

Authors

Authors	Studies
Liu, Q; Liu, R; Lu, L; Pu, Y; Wang, S; Yin, L; Zhang, H; Zhang, Y; Zhao, C; Zhou, Q	1
Bednarz, H; Ernst, R; Fatangare, A; Giampà, M; Kampa, JM; Niehaus, K; Riefke, B; Sahin, M; Slopianka, M	1
Han, X; Lei, X; Li, J; Liu, L; Mao, Y; Qian, Y; Tang, J; Wang, Y; Xu, Q; Zeng, M; Zhang, J; Zhong, W	1
Du, S; Jin, S; Liu, M; Yan, H	1
Li, CM; Li, XB; Liu, XL; Ma, SC; Mao, YM; Ming, YN; Wang, XL; Wang, ZY; Zhang, JY	1
Chenggang, Z; Dongchen, L; Jianjun, L; Liansheng, W; Naiqiong, W; Qian, D; Yanjun, Z; Ying, G; Yuanlin, G; Zhanying, H	1
Li, Q; Ma, Y; Mu, X; Song, L; Wang, D; Yin, R; Zhao, X	1
Athmouni, K; Ayadi, H; El Feki, A; Mkadmini Hammi, K	1
Burkova, VN; Korshunov, DA; Udut, VV; Vaizova, OE; Vengerovskiĭ, AI	1
Inafuku, A; Inafuku, M; Nagao, K; Oku, H; Taira, N; Toda, T; Yanagita, T	1
Dygai, AM; Udut, VV; Vengerovsky, AI	1
Adewoles, IF; Irabor, AE; Kuti, MA; Ogunbode, O; Otegbayo, JA	1
Cherenkov, VG; Petrov, AB; Strozhenkov, MM; Vasil'eva, TM	1
Cao, H; Chen, D; Lu, J; Ma, J; Su, X; Sun, H; Wang, Y; Yang, X; Yu, J; Zhu, C	1
Kim, S; Kwon, J; Na, JY; Song, K	1
Kamei, M; Kimura, F; Miyazawa, T; Nakagawa, K; Suzuki, K; Yamamoto, T	1
Cai, L; He, K; Liu, H; Shi, Q; Woolf, TF	1
Dvornichenko, VV; Morikov, DD; Morikova, EG	1
Goda, K; Kobayashi, A; Maekawa, K; Saito, K; Saito, Y; Sugai, S; Yamada, N	1
Chamulitrat, W; Pathil, A; Stremmel, W; Warth, A	1
Bukshuk, AA; Maslovskiĭ, LV; Minushkin, ON	1
Akhundzhanova, LL; Aripov, OA; Khalimbetov, GS	1
PETZOLD, H; ROSAM, E	1
DELUTTEROTTI, A; SARTORI, S; VALAGUSSA, L	1
Estany, C; Gómez, L; Martí, JM; Martino, R; Sierra, J; Subirà, M	1
Chiji, H; Fukushima, M; Han, KH; Lee, CH; Nakano, M; Ohba, K; Sekikawa, M; Shimada, K	1
Avorn, J; Fischer, MA; Rubin, RH; Winkelmayer, WC	1
Leather, H; Wingard, JR	1
Harada, E; Imanaka, H; Ishikado, A; Makino, T; Takeuchi, T	1
Afifi, NN; El-Samaligy, MS; Mahmoud, EA	1
Gantait, A; Maiti, K; Mukherjee, K; Mukherjee, PK; Saha, BP	1
Agellon, LB; Li, Z; Vance, DE	1
Chamilos, G; Chemaly, R; Kontoyiannis, DP; Lewis, RE; Luna, M; Raad, II	1
Horning, MG; Hughes, H; Lauterburg, BH; Mitchell, JR; Smith, CV	1
Boyle, M; Mulligan, K; Neubauer, KA; O'Neill, D; Royston, VH; Scott, M; Surmon, DJ; Wilcock, GK	1
Gauthier, L; Gauthier, S	1
Abakumova, OIu; Fedorova, LM; Gavril'chak, AV; Karagiulian, SR; Kliashchitskiĭ, BA; Kovaleva, GG; Kutsenko, NG; Li, VS; Mitina, VKh; Podobed, OV; Popov, AA; Shekhter, AB	1
Grundy, SM; Tatò, F; Vega, GL	1
Hirano, K; Murakami, T; Nagamura, Y	1
Glasa, J; Hlavatý, I; Holomán, J; Lukácsová, M; Prachar, V; Veningerová, M	1
Saratikov, AS; Vengerovskiĭ, AI	1
Philips, DL; Sallah, S; Sallah, W; Semelka, RC; Vainright, JR	1
Kolbasov, SE; Lebedev, VP; Melikhova, MV; Stroĭkova, GV; Zamuruev, ON	1
Bonorris, GG; Marks, JW; Pearlman, BJ; Schoenfield, LJ	1
Kuiken, LB; Ragland, JB; Sabesin, SM	1
Goldstein, LI; Schoenfield, LJ	1
Bartsch, GG; Gerber, GB	1
Bartsch, GG; Deroo, J; Gerber, GB	1
Lohmann, J; Rauen, HM; Schriewer, H	1
Bartsch, GG; Brachtel, D; Gallenkamp, H; Löhr, JP; Richter, E	1
Conti, M; Magistretti, MJ; Malandrino, S	1
Aripov, AN; Atabekov, AG; Dombrovskaya, NV; Fesenko, LM; Gagel'gans, AI; Gizatullina, ZZ; Mokhova, EN	1
Chatellier, G; Lacomblez, L	1
Wendel, A; Werner, C	1
Put, A; Samochowiec, L; Wójcicki, J; Wyczarska-Szok, K	1
Saratikov, AS; Sedykh, IM; Vengerovskiĭ, AI	1
Archakov, AI; Dobrynina, OV; Shatinina, SZ	1
Chuchalin, VS; Paul's, OV; Saratikov, AS; Vengerovskiĭ, AI	1
Drogovoz, SM; Porokhniak, LA; Rogozhin, BA	1
Maiwald, L	1
Costanzo, V; Granata, M; Lazzara, A; Maucceri, G	1
Skakun, NP; Stepanova, NIu	1
Campbell, TC; Hayes, JR	1
Oberdisse, E; von Lehmann, V	1
Sgoutas, DS	1
Betzing, H; Lekim, D	1
Rauen, HM; Schriewer, H	2
Kattermann, R; Wolfrum, DI	1
Edwards, KD; Galli, C; Paoletti, R; Usardi, MM	1
Shimizu, Y	1

Reviews

4 review(s) available for phosphatidylcholines and Acute Liver Injury, Drug-Induced

Article	Year
What have we learned from the THA trials to facilitate testing of new AChE inhibitors. Progress in brain research, 1993, Volume: 98 Topics: Alzheimer Disease; Chemical and Drug Induced Liver Injury; Cholinesterase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Diseases; Humans; Phosphatidylcholines; Psychological Tests; Research Design; Tacrine; Treatment Outcome	1993
Gallstone dissolution--a progress report. Clinics in gastroenterology, 1979, Volume: 8, Issue:1 Topics: Animals; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Contraceptives, Oral, Synthetic; Deoxycholic Acid; Diarrhea; Enterohepatic Circulation; Estrogens; Female; Gallstones; Humans; Liver; Male; Phosphatidylcholines; Pregnancy; Recurrence; Risk	1979
Gallstones: pathogenesis and medical treatment. Advances in internal medicine, 1975, Volume: 20 Topics: Adult; Animals; Arizona; Bile; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Fasting; Female; Guinea Pigs; Humans; Indians, North American; Liver; Male; Middle Aged; Minnesota; Phosphatidylcholines	1975
Role of nutrition in the drug-metabolizing enzyme system. Pharmacological reviews, 1974, Volume: 26, Issue:3 Topics: Ascorbic Acid Deficiency; Calcium; Carbohydrates; Carcinogens; Catalysis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Dietary Proteins; Fatty Acids; Humans; Iron Deficiencies; Kinetics; Lipids; Lipotropic Agents; Liver; Magnesium Deficiency; Mixed Function Oxygenases; Mutagens; Nicotinic Acids; Nutritional Physiological Phenomena; Oxidoreductases; Pharmaceutical Preparations; Phenobarbital; Phosphatidylcholines; Protein Deficiency; Riboflavin Deficiency; Thiamine Deficiency; Trace Elements; Vitamin A Deficiency	1974

Trials

5 trial(s) available for phosphatidylcholines and Acute Liver Injury, Drug-Induced

Article	Year
A Multicenter and Randomized Controlled Trial of Bicyclol in the Treatment of Statin-Induced Liver Injury. Medical science monitor : international medical journal of experimental and clinical research, 2017, Dec-04, Volume: 23 Topics: Adult; Aged; Alanine Transaminase; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Middle Aged; Phosphatidylcholines	2017
Livolin ameliorates elevations in alanine transaminase in HIV infected patients commencing highly active antiretroviral therapy. African journal of medicine and medical sciences, 2012, Volume: 41, Issue:4 Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; HIV Infections; Humans; Male; Middle Aged; Nevirapine; Phosphatidylcholines; Treatment Outcome; Vitamin B Complex; Vitamin E; Young Adult	2012
[Possibilities of remaxol in prevention of toxic hepatitis during chemotherapy for cancer patients]. Voprosy onkologii, 2013, Volume: 59, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neoplasms; Patient Selection; Phosphatidylcholines; Protective Agents; Succinates; Treatment Outcome	2013
Low-dose amphotericin B lipid complex vs. conventional amphotericin B for empirical antifungal therapy of neutropenic fever in patients with hematologic malignancies--a randomized, controlled trial. European journal of haematology, 2004, Volume: 72, Issue:5 Topics: Adult; Amphotericin B; Antifungal Agents; Antineoplastic Combined Chemotherapy Protocols; Chemical and Drug Induced Liver Injury; Combined Modality Therapy; Drug Combinations; Female; Fever of Unknown Origin; Hematologic Neoplasms; Humans; Hypokalemia; Immunocompromised Host; Incidence; Kidney Diseases; Male; Middle Aged; Mycoses; Neutropenia; Peripheral Blood Stem Cell Transplantation; Phosphatidylcholines; Phosphatidylglycerols; Treatment Outcome	2004
Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Français d'Etude de la Tetrahydroaminoacridine. BMJ (Clinical research ed.), 1990, Feb-24, Volume: 300, Issue:6723 Topics: Aged; Aged, 80 and over; Alzheimer Disease; Aminoacridines; Behavior; Chemical and Drug Induced Liver Injury; Cognition; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Multicenter Studies as Topic; Phosphatidylcholines; Psychological Tests; Randomized Controlled Trials as Topic; Tacrine	1990

Other Studies

62 other study(ies) available for phosphatidylcholines and Acute Liver Injury, Drug-Induced

Article	Year
Lipid metabolism disorders contribute to hepatotoxicity of ICR mice induced by nitrosamines exposure. Environment international, 2022, Volume: 167 Topics: Animals; Chemical and Drug Induced Liver Injury; Fatty Acids; Lipid Metabolism; Lipid Metabolism Disorders; Liver; Mice; Mice, Inbred ICR; Nitrosamines; Phosphatidylcholines; Phosphatidylethanolamines	2022
Mass spectrometry imaging reveals lipid upregulation and bile acid changes indicating amitriptyline induced steatosis in a rat model. Toxicology letters, 2020, Jun-01, Volume: 325 Topics: Amitriptyline; Animals; Antidepressive Agents, Tricyclic; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Lipid Metabolism; Liver; Male; Mass Spectrometry; Organ Size; Phosphatidylcholines; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Up-Regulation	2020
Exploring the efficacy and safety of polyene phosphatidylcholine for treatment of drug-induced liver injury using the Roussel Uclaf causality assessment method: a propensity score matching comparison. The Journal of international medical research, 2021, Volume: 49, Issue:8 Topics: Chemical and Drug Induced Liver Injury; Humans; Phosphatidylcholines; Propensity Score; Retrospective Studies	2021
Effect of oxymatrine HSPC liposomes on improving bioavailability, liver target distribution and hepatoprotective activity of oxymatrine. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2017, Jun-15, Volume: 104 Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Drug Liberation; Kidney; Liposomes; Liver; Male; Matrines; Mice; Myocardium; Phosphatidylcholines; Protective Agents; Quinolizines; Spleen; Tissue Distribution	2017
Liquid chromatography mass spectrometry-based profiling of phosphatidylcholine and phosphatidylethanolamine in the plasma and liver of acetaminophen-induced liver injured mice. Lipids in health and disease, 2017, Aug-14, Volume: 16, Issue:1 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Choline Kinase; Chromatography, Liquid; Gene Expression Regulation; Hepatocytes; Injections, Intraperitoneal; Liver; Male; Mass Spectrometry; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Phospholipases	2017
Hepatic toxicity following actinomycin D chemotherapy in treatment of familial gestational trophoblastic neoplasia: A case report. Medicine, 2018, Volume: 97, Issue:38 Topics: Adaptor Proteins, Signal Transducing; Administration, Intravenous; Antibiotics, Antineoplastic; Asian People; Chemical and Drug Induced Liver Injury; Chorionic Gonadotropin, beta Subunit, Human; Dactinomycin; Drug-Related Side Effects and Adverse Reactions; Female; Gestational Trophoblastic Disease; Humans; Hypolipidemic Agents; Liver; Lung Neoplasms; Mutation; Neoplasm Staging; Phosphatidylcholines; Pregnancy; Proteins; Saponins; Tomography, X-Ray Computed; Treatment Outcome; Triterpenes; Young Adult	2018
Development of catechin-phospholipid complex to enhance the bioavailability and modulatory potential against cadmium-induced oxidative stress in rats liver. Archives of physiology and biochemistry, 2020, Volume: 126, Issue:1 Topics: Administration, Oral; Animals; Antioxidants; Biological Availability; Cadmium Chloride; Catalase; Catechin; Chemical and Drug Induced Liver Injury; Drug Administration Schedule; Drug Carriers; Gene Expression; Glutathione; Glutathione Peroxidase; Lipid Peroxidation; Liver; Liver Function Tests; Male; Malondialdehyde; Oxidative Stress; Phosphatidylcholines; Rats; Rats, Wistar; Superoxide Dismutase	2020
[The effect of phospholipid hepatoprotectors on lipid peroxidation in liver and content of cytokines in the blood in experimental pathology caused by isoniazid]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2012, Issue:6 Topics: Alkaline Phosphatase; Animals; Antioxidants; Antitubercular Agents; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Interleukin-10; Isoniazid; Lipid Peroxidation; Male; Phosphatidylcholines; Phospholipids; Rats; Transaminases; Tumor Necrosis Factor-alpha	2012
Dietary phosphatidylinositol protects C57BL/6 mice from concanavalin A-induced liver injury by modulating immune cell functions. Molecular nutrition & food research, 2013, Volume: 57, Issue:9 Topics: Animals; Chemical and Drug Induced Liver Injury; Concanavalin A; Cytokines; Diet; Liver; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylinositols; Phosphatidylserines; Soybean Oil	2013
Effects of phospholipid hepatoprotectors on apoptosis during experimental liver pathology induced by isoniazid and paracetamol. Bulletin of experimental biology and medicine, 2013, Volume: 154, Issue:5 Topics: Acetaminophen; Alkaline Phosphatase; Animals; Apoptosis; Bilirubin; Carotenoids; Chemical and Drug Induced Liver Injury; Drug Combinations; Granulocytes; Interleukin-10; Isoniazid; Liver Function Tests; Lymphocytes; Male; Phosphatidylcholines; Phospholipids; Rats; Succinic Acid; Transaminases; Tumor Necrosis Factor-alpha	2013
UPLC-MS-based serum metabonomics for identifying acute liver injury biomarkers in Chinese miniature pigs. Toxicology letters, 2014, Mar-21, Volume: 225, Issue:3 Topics: Animals; Bile Acids and Salts; Biomarkers; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Fatty Acids; Lysophosphatidylcholines; Male; Metabolomics; Multivariate Analysis; Phosphatidylcholines; Random Allocation; Spectrometry, Mass, Electrospray Ionization; Swine; Swine, Miniature; Tandem Mass Spectrometry	2014
Hepatoprotective effect of phosphatidylcholine against carbon tetrachloride liver damage in mice. Biochemical and biophysical research communications, 2015, May-01, Volume: 460, Issue:2 Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Male; Mice; Mice, Inbred ICR; Phosphatidylcholines	2015
Carbon tetrachloride-induced hepatic and renal damages in rat: inhibitory effects of cacao polyphenol. Bioscience, biotechnology, and biochemistry, 2015, Volume: 79, Issue:10 Topics: Acute Kidney Injury; Animals; Antioxidants; Cacao; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Gene Expression; Glutathione; Glutathione Peroxidase; Injections, Intraperitoneal; Kidney; Lipid Peroxidation; Liver; Male; Malondialdehyde; Oxidative Stress; Phosphatidylcholines; Phytotherapy; Plant Extracts; Polyphenols; Rats; Rats, Inbred F344; RNA, Messenger	2015
Inhibition of MDR3 Activity in Human Hepatocytes by Drugs Associated with Liver Injury. Chemical research in toxicology, 2015, Oct-19, Volume: 28, Issue:10 Topics: ATP Binding Cassette Transporter, Subfamily B; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Deuterium; Hepatocytes; Humans; Itraconazole; Phosphatidylcholines; Tandem Mass Spectrometry; Taurocholic Acid; Verapamil	2015
[Pharmacoeconomic Analysis of the Use of Hepatoprotectors in Management of Drug-Associated Liver Injury Due to Hodgkin's Lymphoma Chemotherapy]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2015, Volume: 60, Issue:7-8 Topics: Antineoplastic Agents; Case-Control Studies; Chemical and Drug Induced Liver Injury; Cost-Benefit Analysis; Disease Management; Hodgkin Disease; Humans; Liver; Phosphatidylcholines; Protective Agents; Retrospective Studies; S-Adenosylmethionine; Succinates; Treatment Outcome	2015
Arachidonic acid-containing phosphatidylcholine characterized by consolidated plasma and liver lipidomics as an early onset marker for tamoxifen-induced hepatic phospholipidosis. Journal of applied toxicology : JAT, 2017, Volume: 37, Issue:8 Topics: Animals; Arachidonic Acid; Biomarkers; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Lipid Metabolism; Lipidoses; Liver; Male; Phosphatidylcholines; Rats, Sprague-Dawley; Tamoxifen	2017
The synthetic bile acid-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide suppresses TNFα-induced liver injury. Journal of hepatology, 2011, Volume: 54, Issue:4 Topics: Animals; Apoptosis; Cell Line; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cytokines; Galactosamine; Gene Expression; Humans; Inflammation Mediators; Lipopolysaccharides; Lysophospholipids; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phospholipases A2; Phospholipids; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid	2011
[The use of hepatic protectors in clinical practice]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2012, Volume: 112, Issue:10 Pt 2 Topics: Amino Acids; Chemical and Drug Induced Liver Injury; Cytoprotection; Drug Combinations; Flavonoids; Hepatocytes; Humans; Liver; Phosphatidylcholines; Protective Agents; Pyridoxine; Pyrrolidonecarboxylic Acid; Ursodeoxycholic Acid	2012
[Membrane-stabilizing effect of phospholipid liposomes in toxic hepatitis]. Klinicheskaia laboratornaia diagnostika, 2002, Issue:6 Topics: Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Glycyrrhizic Acid; Gossypium; Lipid Peroxidation; Liposomes; Liver; Male; Phosphatidylcholines; Rats; Unithiol	2002
[THE EFFECT OF ESSENTIAL PHOSPHOLIPIDS ON THE ETHIONINE DAMAGE OF THE RAT LIVER]. Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1963, Volume: 23 Topics: Chemical and Drug Induced Liver Injury; Ethionine; Hepatitis; Liver; Liver Diseases; Necrosis; Phosphatidylcholines; Phospholipids; Rats; Research; Toxicology	1963
[RELATIONS BETWEEN THE ANTINECROTIC AND HEPATOPROTECTIVE ACTION OF ESSENTIAL PHOSPHOLIPIDS AND ENZYMATIC ACTIVITY IN THE BLOOD OF RATS POISONED WITH CARBON TETRACHLORIDE]. Rivista di patologia e clinica, 1964, Volume: 19 Topics: Alanine Transaminase; Aspartate Aminotransferases; Blood; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Clinical Enzyme Tests; Fatty Acids; Fatty Acids, Essential; Fructose-Bisphosphate Aldolase; Glucosephosphate Dehydrogenase; Hepatitis; L-Lactate Dehydrogenase; Malate Dehydrogenase; Pharmacology; Phosphatidylcholines; Rats; Research; Toxicology	1964
Hepatoprotective effects of the water extract from adzuki bean hulls on acetaminophen-induced damage in rat liver. Journal of nutritional science and vitaminology, 2004, Volume: 50, Issue:5 Topics: Acetaminophen; Animals; Aspartate Aminotransferases; Catalase; Chemical and Drug Induced Liver Injury; Fabaceae; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Liver; Liver Diseases; Male; Phosphatidylcholines; Phosphatidylethanolamines; Plant Extracts; Rats; Rats, Inbred F344; Water	2004
The hepatotoxicity of antifungal medications in bone marrow transplant recipients. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Aug-01, Volume: 41, Issue:3 Topics: Adult; Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Case-Control Studies; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Drug Combinations; Female; Fluconazole; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Phosphatidylcholines; Phosphatidylglycerols; Risk Factors	2005
Hepatotoxicity associated with antifungal therapy after bone marrow transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, Aug-01, Volume: 41, Issue:3 Topics: Amphotericin B; Antifungal Agents; Bone Marrow Transplantation; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Drug Combinations; Fluconazole; Humans; Phosphatidylcholines; Phosphatidylglycerols; Risk Factors	2005
Liposomalization of lactoferrin enhanced it's anti-inflammatory effects via oral administration. Biological & pharmaceutical bulletin, 2005, Volume: 28, Issue:9 Topics: Absorption; Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drug Carriers; Guinea Pigs; Intestinal Absorption; Jugular Veins; Lactoferrin; Liposomes; Lymph; Mice; Mice, Inbred BALB C; Passive Cutaneous Anaphylaxis; Phosphatidylcholines; Phytosterols; Rats; Rats, Wistar	2005
Evaluation of hybrid liposomes-encapsulated silymarin regarding physical stability and in vivo performance. International journal of pharmaceutics, 2006, Aug-17, Volume: 319, Issue:1-2 Topics: Administration, Buccal; Alanine Transaminase; Amines; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chemistry, Pharmaceutical; Cholesterol; Drug Stability; Drug Storage; Evaluation Studies as Topic; Liposomes; Liver; Liver Diseases; Oxidative Stress; Particle Size; Phosphatidylcholines; Polysorbates; Rats; Silymarin; Temperature	2006
Curcumin-phospholipid complex: Preparation, therapeutic evaluation and pharmacokinetic study in rats. International journal of pharmaceutics, 2007, Feb-07, Volume: 330, Issue:1-2 Topics: Animals; Area Under Curve; Calorimetry, Differential Scanning; Carbon Tetrachloride Poisoning; Catalase; Chemical and Drug Induced Liver Injury; Curcumin; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Half-Life; Male; Phosphatidylcholines; Rats; Rats, Wistar; Solubility; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances	2007
A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis. Biochimica et biophysica acta, 2007, Volume: 1771, Issue:7 Topics: Animals; Apolipoprotein A-I; Chemical and Drug Induced Liver Injury; Choline Deficiency; Female; Glyburide; Hepatocytes; Homeostasis; Lipoproteins, HDL; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Phosphatidylcholines; Phosphatidylethanolamine N-Methyltransferase; Phosphatidylethanolamines; Sex Characteristics	2007
Effects of liposomal amphotericin B versus an amphotericin B lipid complex on liver histopathology in patients with hematologic malignancies and invasive fungal infections: a retrospective, nonrandomized autopsy study. Clinical therapeutics, 2007, Volume: 29, Issue:9 Topics: Adolescent; Adult; Aged; Amphotericin B; Antifungal Agents; Autopsy; Chemical and Drug Induced Liver Injury; Drug Carriers; Drug Combinations; Female; Hematologic Neoplasms; Humans; Liposomes; Liver; Male; Middle Aged; Mycoses; Phosphatidylcholines; Phosphatidylglycerols; Retrospective Studies	2007
Overview of alkylation and peroxidation mechanisms in acute lethal hepatocellular injury by chemically reactive metabolites. Seminars in liver disease, 1981, Volume: 1, Issue:2 Topics: Acetaminophen; Alkylation; Animals; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Ethane; Glutathione; Liver; Liver Diseases; Male; Mice; Pentanes; Peroxides; Pharmaceutical Preparations; Phosphatidylcholines	1981
An evaluation of the efficacy and safety of tetrahydroaminoacridine (THA) without lecithin in the treatment of Alzheimer's disease. Age and ageing, 1993, Volume: 22, Issue:5 Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Chemical and Drug Induced Liver Injury; Female; Humans; Liver Function Tests; Male; Middle Aged; Neuropsychological Tests; Phosphatidylcholines; Quality of Life; Tacrine	1993
[Stimulation of regenerative processes and correction of the functional activity of the liver in its partial resection and toxic lesions]. Vestnik Rossiiskoi akademii meditsinskikh nauk, 1996, Issue:5 Topics: Animals; Anti-Bacterial Agents; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; DNA; Glycine max; Helianthus; Hepatectomy; Hepatocyte Growth Factor; Liver; Liver Cirrhosis, Experimental; Liver Regeneration; Phosphatidylcholines; Prodigiozan; Rats; RNA	1996
Effects of crystalline nicotinic acid-induced hepatic dysfunction on serum low-density lipoprotein cholesterol and lecithin cholesteryl acyl transferase. The American journal of cardiology, 1998, Mar-15, Volume: 81, Issue:6 Topics: Acyltransferases; Chemical and Drug Induced Liver Injury; Cholesterol, LDL; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Middle Aged; Niacin; Phosphatidylcholines	1998
Ethanolamine stimulates repair processes in acute CCl4 damage of mouse liver. Toxicology letters, 1998, Jan-31, Volume: 94, Issue:2 Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bromodeoxyuridine; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; DNA; ErbB Receptors; Ethanolamine; Liver; Liver Regeneration; Male; Mice; Phosphatidylcholines; Phosphatidylethanolamines	1998
[Positive effects of essential phospholipids and improvement of life style in patients with toxic liver injury]. Bratislavske lekarske listy, 1998, Volume: 99, Issue:2 Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Fatty Liver; Female; Humans; Male; Middle Aged; Occupational Diseases; Phosphatidylcholines; Temperance	1998
[Effects of hepatoprotective agents containing phospholipids on cytochrome P-450-dependent antitoxic liver function during experimental toxic hepatitis]. Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:4 Topics: Animals; Antioxidants; Carbon Tetrachloride Poisoning; Carotenoids; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Drug Combinations; Inactivation, Metabolic; Liver; Male; Microsomes, Liver; Phosphatidylcholines; Phospholipids; Propanols; Rats; Silymarin	1999
Amphotericin B lipid complex for the treatment of patients with acute leukemia and hepatosplenic candidiasis. Leukemia research, 1999, Volume: 23, Issue:11 Topics: Acute Disease; Adult; Amphotericin B; Antifungal Agents; Antineoplastic Agents; Candidiasis; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Leukemia, Myeloid; Liver Diseases; Male; Middle Aged; Phosphatidylcholines; Phosphatidylglycerols; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Splenic Diseases	1999
[Effect of the transcranial electrical stimulation of the endorphinergic brain structures on the functional activity of hepatocytes after toxic exposure]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2000, Volume: 86, Issue:11 Topics: Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Electric Stimulation; Endorphins; Ethylene Dichlorides; Fatty Liver; Hepatocytes; Liver Function Tests; Male; Naloxone; Narcotic Antagonists; Phosphatidylcholines; Protective Agents; Rats; Rats, Wistar	2000
Lipoprotein abnormalities in galactosamine hepatitis: a model of experimental lecithin:cholesterol acyltransferase deficiency. Scandinavian journal of clinical and laboratory investigation. Supplementum, 1978, Volume: 150 Topics: Acute Disease; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Cholesterol Esters; Disease Models, Animal; Female; Galactosamine; Hypolipoproteinemias; Lecithin Cholesterol Acyltransferase Deficiency; Lipids; Lipoproteins; Lysophosphatidylcholines; Phosphatidylcholines; Phospholipids; Rats	1978
Influence of phospholipids on liver damage. II. Changes in lipid content and synthesis after liver damage with carbontetrachloride and other agents. Acta hepato-gastroenterologica, 1975, Volume: 22, Issue:4 Topics: Acetates; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; DNA; Fatty Liver; Hepatectomy; Lipids; Liver; Liver Regeneration; Male; Mice; Mice, Inbred BALB C; Orotic Acid; Phosphatidylcholines; Phospholipids; Rats; Thymus Gland; X-Rays	1975
Influence of phospholids on liver damage. I. Carbontetrachloride poisoning and alterations in amino acid uptake, peroxidation, sialic acid content, and lysosomal enzymes. Acta hepato-gastroenterologica, 1975, Volume: 22, Issue:3 Topics: Aminoisobutyric Acids; Animals; Brain; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Glucuronidase; Liver; Lysosomes; Male; Mice; Mice, Inbred BALB C; Peroxides; Phosphatidylcholines; Rats; Sialic Acids	1975
[The effect of silybin-dihemisuccinate on regulation disorders in phospholipid metabolism in acute galactosamine intoxication in the rat]. Arzneimittel-Forschung, 1975, Volume: 25, Issue:10 Topics: Animals; Chemical and Drug Induced Liver Injury; Flavonoids; Galactosamine; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Palmitic Acids; Phosphatidic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Rats; Silymarin; Triglycerides	1975
Influence of d-galactosamine hydrochloride on lipids and their fatty acid composition in plasma and liver of guinea pigs. Acta hepato-gastroenterologica, 1976, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Fatty Acids; Galactosamine; Linoleic Acids; Linolenic Acids; Lipid Metabolism; Liver; Male; Microsomes, Liver; Oleic Acids; Palmitic Acids; Phosphatidylcholines; Phospholipids; Rats	1976
Protective activity of silipide on liver damage in rodents. Japanese journal of pharmacology, 1992, Volume: 60, Issue:4 Topics: Acetaminophen; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ethanol; Female; Galactosamine; Male; Phosphatidylcholines; Praseodymium; Rats; Rats, Sprague-Dawley; Rats, Wistar; Silymarin	1992
Disturbances in oxidative phosphorylation in the liver of rats with heliotrine-induced hepatitis and restoration by phosphatidylcholine and ATP. Biomedical science, 1991, Volume: 2, Issue:5 Topics: Adenosine Triphosphate; Animals; Chemical and Drug Induced Liver Injury; Drug Synergism; Electron Transport Complex IV; Male; Mitochondria, Liver; Oxidative Phosphorylation; Phosphatidylcholines; Pyrrolizidine Alkaloids; Rats	1991
Hepatic uptake and antihepatotoxic properties of vitamin E and liposomes in the mouse. Chemico-biological interactions, 1990, Volume: 75, Issue:1 Topics: Acetaminophen; Animals; Benzo(a)pyrene; Chemical and Drug Induced Liver Injury; Drug Carriers; Galactosamine; Lipopolysaccharides; Liposomes; Liver; Male; Mice; Phosphatidylcholines; Vitamin E	1990
[Effect of essential phospholipids (EPL) on the course of chronic poisoning with organic solvents in rats]. Medycyna pracy, 1989, Volume: 40, Issue:4 Topics: Animals; Antidotes; Chemical and Drug Induced Liver Injury; Chronic Disease; Drug Evaluation, Preclinical; Hydrocarbons; Liver; Male; Phosphatidylcholines; Rats; Rats, Inbred Strains; Solvents	1989
[Effectiveness of hepatoprotective agents in experimental allyl alcohol poisoning]. Gigiena truda i professional'nye zabolevaniia, 1989, Issue:5 Topics: 1-Propanol; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Flavonoids; Liver; Male; Phosphatidylcholines; Phospholipids; Propanols; Rats; Rats, Inbred Strains; Silymarin	1989
[Phosphatidylcholine-induced repair of damaged hepatocyte membranes in heliotrine poisoning]. Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:4 Topics: Animals; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Activation; Fructose-Bisphosphate Aldolase; Glucose-6-Phosphatase; Liposomes; Male; Microsomes, Liver; Phosphatidylcholines; Pyrrolizidine Alkaloids; Rats	1987
[The effect of hepatoprotectors on lipid metabolism in CCl4-hepatitis]. Biulleten' eksperimental'noi biologii i meditsiny, 1987, Volume: 103, Issue:4 Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Flavonoids; Lipid Metabolism; Lipids; Liver; Male; Phosphatidylcholines; Phospholipids; Rats; Silymarin	1987
[Action of hepatoprotective agents in a tetracycline lesion of the liver]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1987, Volume: 32, Issue:4 Topics: Animals; Bile; Catechin; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Liver; Male; Phosphatidylcholines; Plant Extracts; Rats; Rats, Inbred Strains; Silymarin; Tetracycline	1987
["Essential" phospholipids in liver diseases]. Fortschritte der Medizin, 1986, Apr-10, Volume: 104, Issue:14 Topics: Chemical and Drug Induced Liver Injury; Humans; Liver Diseases; Liver Diseases, Alcoholic; Liver Function Tests; Phosphatidylcholines	1986
[Use of polyunsaturated phosphatidylcholine associated with a vitamin B complex in the treatment of hepatic injuries caused by antitubercular agents]. La Clinica terapeutica, 1986, Sep-30, Volume: 118, Issue:6 Topics: Antitubercular Agents; Chemical and Drug Induced Liver Injury; Drug Therapy, Combination; Humans; Liver Diseases; Phosphatidylcholines; Vitamin B Complex	1986
[Effectiveness of legalon and essentiale in a tetracycline-induced liver lesion]. Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1986, Volume: 31, Issue:10 Topics: Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Drug Evaluation, Preclinical; Drug Therapy, Combination; Flavonoids; Liver Diseases; Male; Phosphatidylcholines; Plants, Medicinal; Rats; Silymarin; Tetracycline	1986
Proceedings: Subcellular distribution of phospholipids in rare-earth induced liver damage. Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl Topics: Animals; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Fatty Liver; Female; Lipoproteins; Liver; Microsomes, Liver; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Praseodymium; Rats; Surface-Active Agents; Time Factors; Triglycerides	1974
Phospholipid changes during hepatic injury caused by carbon tetrachloride. Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4 Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Chromatography, Ion Exchange; Fats, Unsaturated; Fatty Acids; Fatty Liver; Glycerol; Male; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylinositols; Phospholipids; Rats; Sphingomyelins	1967
[The incorporation of essential phospholipids into the organs of intact and galactosamine intoxicated rats]. Arzneimittel-Forschung, 1974, Volume: 24, Issue:8 Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Cardiolipins; Chemical and Drug Induced Liver Injury; Chromatography; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids, Essential; Galactosamine; Hydrolysis; Injections, Intravenous; Isotope Labeling; Liver; Magnetic Resonance Spectroscopy; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipases; Phospholipids; Rats; Tritium	1974
[Relationship between lecithin-lysolecithin and cholesterol-cholesterol esters in the serum of the rat with galactosamine-induced hepatosis]. Experientia, 1972, Nov-15, Volume: 28, Issue:11 Topics: Acute Disease; Acyltransferases; Animals; Chemical and Drug Induced Liver Injury; Cholesterol; Esters; Galactosamine; Injections, Intraperitoneal; Liver; Liver Diseases; Lysophosphatidylcholines; Male; Phosphatidylcholines; Rats; Time Factors	1972
[Lipid metabolism disorders in the rat following parenteral deoxycholate in toxication. Brief report]. Arzneimittel-Forschung, 1973, Volume: 23 Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Deoxycholic Acid; Injections, Intravenous; Lipid Metabolism; Liver; Liver Regeneration; Lysophosphatidylcholines; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Time Factors	1973
[Cholesterol metabolism and plasma lecithin-cholesterol acyl transferase in experimental hepatitis and cholestasis in the rat]. Zeitschrift fur klinische Chemie und klinische Biochemie, 1970, Volume: 8, Issue:4 Topics: Acyltransferases; Animals; Carbon Isotopes; Chemical and Drug Induced Liver Injury; Cholestasis; Cholesterol; Chromatography, Thin Layer; Esters; Hepatitis; Hexosamines; Male; Phosphatidylcholines; Rats; Thiocyanates	1970
Studies on the pharmacological control of hyperlipemia in experimental nephrotic syndrome. Biochemical pharmacology, 1970, Volume: 19, Issue:10 Topics: Animals; Butyrates; Chemical and Drug Induced Liver Injury; Cholesterol; Cholestyramine Resin; Disease Models, Animal; Female; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Liver; Nephrotic Syndrome; Nucleosides; Organ Size; Phosphatidylcholines; Phospholipids; Propionates; Puromycin; Rats; Thyroxine; Triglycerides	1970
Effect of carbon tetrachloride administration on the synthesis of triglycerides and phospholipids in rat liver. Journal of lipid research, 1969, Volume: 10, Issue:5 Topics: Animals; Carbon Isotopes; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Choline; Coenzyme A; Depression, Chemical; Female; In Vitro Techniques; Lipids; Liver; Male; Methionine; Microsomes; Mitochondria, Liver; Nucleotides; Palmitic Acids; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Phosphorus Isotopes; Rats; Triglycerides	1969