Page last updated: 2024-08-17

phosgene and Disease Models, Animal

phosgene has been researched along with Disease Models, Animal in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's2 (8.33)18.2507
2000's6 (25.00)29.6817
2010's13 (54.17)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Cao, C; Dun, Y; He, D; Liu, F; Memete, O; Shao, Y; Shen, J; Zhang, L; Zhou, J1
He, D; Jiang, Z; Shao, Y; Shen, J1
Li, W; Liu, F; Pauluhn, J; Trübel, H; Wang, C1
Gao, F; Hou, L; Liu, Z; Qian, Y; Tian, R1
He, DK; Li, W; Shao, YR; Shen, J; Yuan, Z1
Liu, F; Pauluhn, J; Trübel, H; Wang, C1
He, D; Shao, Y; Shen, J; Wang, J; Zhang, L1
Anderson, DR; Andres, DK; Benton, BJ; Dillman, JF; Hoard-Fruchey, HM; Holmes, WW; Keyser, BM; Paradiso, DC; Ray, R; Rothwell, CC; Sciuto, AM1
Fairhall, SJ; Grainge, C; Jenner, J; Jugg, BJ; Mann, T; Millar, T; Perrott, R; Rice, P; Smith, AJ1
He, DK; Huang, WB; Shen, J; Zhang, L1
Hai, CX; Li, WL; Pauluhn, J1
Doi, H; Ishiguro, N; Katayama, Y; Suzuki, M; Takashima, T; Tamai, I; Wada, Y; Watanabe, Y; Yashio, K1
Shen, J; Yuan, Z; Zhao, J1
Gan, Z; Shen, J; Xu, G; Zhang, L; Zhao, J1
Gan, ZY; He, DK; Shen, J; Zhang, L; Zhong, ZY1
Costa, D; Crissman, K; Hatch, G; Kodavanti, U; Slade, R1
Carpin, LB; Forster, JS; Moran, TS; Sciuto, AM1
Cascio, MB; Forster, JS; Moran, TS; Sciuto, AM1
Clapp, DL; Hess, ZA; Moran, TS; Sciuto, AM1
Hurt, HH; Sciuto, AM1
Carson, A; Costa, DL; Gordon, T; Kodavanti, U; Last, JA; Matthay, MA; Pauluhn, J; Pinkerton, KE; Sciuto, AM1
Ghio, AJ; Hatch, GE1
Karlinsky, JB; Snider, GL1
Burleson, GR; Ehrlich, JP1

Reviews

2 review(s) available for phosgene and Disease Models, Animal

ArticleYear
Therapeutic treatments of phosgene-induced lung injury.
    Inhalation toxicology, 2004, Volume: 16, Issue:8

    Topics: Administration, Inhalation; Animals; Chemical Warfare Agents; Disease Models, Animal; Inhalation Exposure; Lung Diseases; Mice; Pharmaceutical Preparations; Phosgene; Rabbits

2004
Animal models of emphysema.
    The American review of respiratory disease, 1978, Volume: 117, Issue:6

    Topics: Animals; Cadmium; Collagen; Connective Tissue; Disease Models, Animal; Elastin; Humans; Lung; Lung Compliance; Lung Volume Measurements; Nitrogen Dioxide; Pancreatic Elastase; Papain; Phosgene; Pulmonary Alveoli; Pulmonary Circulation; Pulmonary Emphysema; Smoking

1978

Other Studies

22 other study(ies) available for phosgene and Disease Models, Animal

ArticleYear
Single-Cell RNA-Sequencing Reveals Epithelial Cell Signature of Multiple Subtypes in Chemically Induced Acute Lung Injury.
    International journal of molecular sciences, 2022, Dec-23, Volume: 24, Issue:1

    Topics: Acute Lung Injury; Alveolar Epithelial Cells; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Epithelial Cells; Lung; Lung Injury; Phosgene; Rats; RNA

2022
Comprehensive Analysis of the Profiles of Differentially Expressed mRNAs, lncRNAs, and circRNAs in Phosgene-Induced Acute Lung Injury.
    BioMed research international, 2021, Volume: 2021

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Lung; Mesenchymal Stem Cells; Phosgene; Rats; RNA; Transcriptome

2021
Rat models of acute lung injury: exhaled nitric oxide as a sensitive, noninvasive real-time biomarker of prognosis and efficacy of intervention.
    Toxicology, 2013, Aug-09, Volume: 310

    Topics: Acute Lung Injury; Animals; Asthma; Biomarkers; Breath Tests; Carbon Dioxide; Chlorine; Disease Models, Animal; Equipment Design; Exhalation; Inhalation Exposure; Lipopolysaccharides; Male; Nitric Oxide; Phosgene; Plethysmography, Impedance; Rats; Rats, Inbred BN; Rats, Wistar; Toluene 2,4-Diisocyanate

2013
Network clusters analysis based on protein-protein interaction network constructed in phosgene-induced acute lung injury.
    Lung, 2013, Volume: 191, Issue:5

    Topics: Acute Lung Injury; Animals; Cell Cycle; Cell Cycle Proteins; Cluster Analysis; Disease Models, Animal; Gene Regulatory Networks; Glutathione; Homeodomain Proteins; Lung; Male; Mice; Mice, Inbred Strains; Myeloid Ecotropic Viral Integration Site 1 Protein; Neoplasm Proteins; Nuclear Proteins; Phosgene; Protein Interaction Domains and Motifs; Signal Transduction; Spliceosomes; Transcription Factors; Transcriptome

2013
[Effects of phosphorylated mitogen-activated protein kinases on phosgene inhalation-induced lung injury in rats and its relationship with matrix metalloproteinase].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2013, Volume: 29, Issue:3

    Topics: Animals; Burns, Inhalation; Cytokines; Disease Models, Animal; Flavonoids; Imidazoles; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Phosgene; Phosphorylation; Pyridines; Rats; Rats, Wistar

2013
Single high-dose dexamethasone and sodium salicylate failed to attenuate phosgene-induced acute lung injury in rats.
    Toxicology, 2014, Jan-06, Volume: 315

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemical Warfare Agents; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Glucocorticoids; Male; Nitric Oxide; Phosgene; Pulmonary Edema; Rats; Severity of Illness Index; Sodium Salicylate

2014
[Effects of adenovirus-delivered angiopoietin-1 siRNA on expression of matrix metalloproteinases in rats with acute lung injury induced by phosgene].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2014, Volume: 32, Issue:9

    Topics: Acute Lung Injury; Adenoviridae; Angiopoietin-1; Animals; Bronchoalveolar Lavage Fluid; Chemical Warfare Agents; Disease Models, Animal; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinases; Phosgene; Rats; RNA, Messenger; RNA, Small Interfering; Tissue Inhibitor of Metalloproteinase-1

2014
Conceptual approaches for treatment of phosgene inhalation-induced lung injury.
    Toxicology letters, 2016, Feb-26, Volume: 244

    Topics: Animals; Antidotes; Chemical Warfare Agents; Disease Models, Animal; Inhalation Exposure; Lung; Lung Injury; Male; Mice; Molecular Targeted Therapy; Phosgene; Signal Transduction

2016
Furosemide in the treatment of phosgene induced acute lung injury.
    Journal of the Royal Army Medical Corps, 2010, Volume: 156, Issue:4

    Topics: Acute Lung Injury; Administration, Inhalation; Animals; Disease Models, Animal; Female; Furosemide; Nebulizers and Vaporizers; Oxidation-Reduction; Phosgene; Sodium Potassium Chloride Symporter Inhibitors; Swine

2010
[Effects of dexamethasone pretreatment on expression of matrix metalloproteinase-9 in rats with acute lung injury induced by phosgene].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:4

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Dexamethasone; Disease Models, Animal; Male; Matrix Metalloproteinase 9; Phosgene; Rats; Rats, Sprague-Dawley

2011
Inhaled nitric oxide aggravates phosgene model of acute lung injury.
    Inhalation toxicology, 2011, Volume: 23, Issue:13

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Drug Synergism; Enzyme Inhibitors; Irritants; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosgene; Plethysmography, Whole Body; Proteins; Pyruvates; Rats; Rats, Wistar

2011
Synthesis of [¹¹C]uric acid, using [¹¹C]phosgene, as a possible biomarker in PET imaging for diagnosis of gout.
    Bioorganic & medicinal chemistry letters, 2012, Jan-01, Volume: 22, Issue:1

    Topics: Animals; Automation; Biomarkers; Carbon Isotopes; Chromatography, High Pressure Liquid; Disease Models, Animal; Gout; Hyperuricemia; Image Processing, Computer-Assisted; Models, Chemical; Phosgene; Positron-Emission Tomography; Rats; Temperature; Uric Acid

2012
[The changes of the ratio of angiopoietin-2 to angiopoietin-1 in the acute lung injury induced by phosgene in rats].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2011, Volume: 29, Issue:8

    Topics: Acute Lung Injury; Angiopoietin-1; Angiopoietin-2; Animals; Disease Models, Animal; Male; Phosgene; Rats; Rats, Sprague-Dawley

2011
Ulinastatin reduces pathogenesis of phosgene-induced acute lung injury in rats.
    Toxicology and industrial health, 2014, Volume: 30, Issue:9

    Topics: Acute Lung Injury; Administration, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Glycoproteins; Intercellular Adhesion Molecule-1; Interleukin-15; Male; Phosgene; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley

2014
[Protective effect of melatonin in rats with phosgene-induced lung injury].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2012, Volume: 30, Issue:11

    Topics: Acute Lung Injury; Animals; Disease Models, Animal; Male; Malondialdehyde; Melatonin; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Phosgene; Rats; Rats, Sprague-Dawley; Superoxide Dismutase

2012
An 'injury-time integral' model for extrapolating from acute to chronic effects of phosgene.
    Toxicology and industrial health, 2001, Volume: 17, Issue:5-10

    Topics: Animals; Bronchoalveolar Lavage; Chemical Warfare Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Environmental Exposure; Humans; Lung; Male; Models, Theoretical; Phosgene; Rats; Rats, Inbred F344; Risk Assessment; Time Factors

2001
Chronological changes in electrolyte levels in arterial blood and bronchoalveolar lavage fluid in mice after exposure to an edemagenic gas.
    Inhalation toxicology, 2003, Volume: 15, Issue:7

    Topics: Administration, Inhalation; Air Pollutants; Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dose-Response Relationship, Drug; Electrolytes; Lung; Male; Mice; Mice, Inbred Strains; Phosgene; Time Factors

2003
The fate of antioxidant enzymes in bronchoalveolar lavage fluid over 7 days in mice with acute lung injury.
    Inhalation toxicology, 2003, Volume: 15, Issue:7

    Topics: Animals; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Enzymes; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Male; Mice; Mice, Inbred Strains; Phosgene; Respiratory Distress Syndrome; Superoxide Dismutase

2003
The temporal profile of cytokines in the bronchoalveolar lavage fluid in mice exposed to the industrial gas phosgene.
    Inhalation toxicology, 2003, Volume: 15, Issue:7

    Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Chemokine CXCL2; Chemokines; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Interleukin-1; Interleukin-10; Interleukin-4; Interleukin-6; Male; Mice; Mice, Inbred Strains; Phosgene; Respiratory Distress Syndrome; Time Factors; Tumor Necrosis Factor-alpha

2003
Workshop summary: phosgene-induced pulmonary toxicity revisited: appraisal of early and late markers of pulmonary injury from animal models with emphasis on human significance.
    Inhalation toxicology, 2007, Volume: 19, Issue:10

    Topics: Animals; Biomarkers; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Humans; Lung; Lung Diseases; Mice; Phosgene; Rats; Species Specificity; Time Factors; Virginia

2007
Tolerance to phosgene is associated with a neutrophilic influx into the rat lung.
    American journal of respiratory and critical care medicine, 1996, Volume: 153, Issue:3

    Topics: Adaptation, Physiological; Administration, Inhalation; Administration, Topical; Animals; Bronchoalveolar Lavage Fluid; Cell Movement; Colchicine; Dextrans; Disease Models, Animal; Drug Tolerance; Lung; Male; Neutrophils; Nitrogen Oxides; Oxidants; Oxygen; Ozone; Phosgene; Proteins; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Trachea

1996
Enhanced and prolonged pulmonary influenza virus infection following phosgene inhalation.
    Journal of toxicology and environmental health, 1991, Volume: 34, Issue:2

    Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cell Count; Cell Survival; Disease Models, Animal; Disease Susceptibility; Immune Tolerance; Influenza A virus; Lung; Lymphocytes; Macrophages; Male; Neutrophils; Orthomyxoviridae Infections; Phosgene; Rats; Rats, Inbred F344; Viral Plaque Assay; Virus Replication

1991