Page last updated: 2024-09-04

phorbols and Skin Neoplasms

phorbols has been researched along with Skin Neoplasms in 122 studies

Research

Studies (122)

TimeframeStudies, this research(%)All Research%
pre-1990121 (99.18)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (0.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, L; Chen, RM; Han, J; Hong, L; Hu, WY; Liao, R; Sun, P; Xu, Z; Yoshizuka, N; Yu, G1
Astrup, EG; Elgjo, K; Iversen, OH1
Belman, S; Garte, SJ2
Reyes-Mayes, D; Volm, M; Wayss, K1
Indo, K; Miyaji, H1
Boutwell, RK; Perchellet, JP1
Schweizer, J; Winter, H1
Bhide, SV; Munir, KM; Rao, KV1
Pashko, LL; Rovito, RJ; Schwartz, AG; Sobel, EL; Williams, JR1
Ashendel, CL; Boutwell, RK; Takigawa, M; Verma, AK1
Ashendel, CL; Boutwell, RK; Verma, AK1
Kriegel, H; Schmahl, W; Senft, E1
Argyris, TS; Fürstenberger, G; Marks, F; Richter, H1
Boutwell, RK; Conrad, EA; Verma, AK1
Eisinger, M; Greenebaum, E; Nicolaides, M; Vogel, RH; Weinstein, IB1
Blumberg, PM; Delclos, KB; Dunn, JA; Jaken, S; Leach, KL; Yeh, E1
Mastro, AM1
Jetten, AM; Kawamura, H; Strickland, JE; Yuspa, SH1
Argyris, TS1
Kato, R; Nakadate, T; Sugimura, T; Yamamoto, S1
Goerttler, K; Hesse, B; Loehrke, H; Schweizer, J6
Klein-Szanto, AJ; Mamrack, MD; Reiners, JJ; Slaga, TJ1
Aizu, E; Kato, R; Nakadate, T; Yamamoto, S3
Fürstenberger, G; Goerttler, K; Kinzel, V; Loehrke, H; Marks, F1
Decina, PC; Diamond, L; DiGiovanni, J; Prichett, WP1
Fürstenberger, G; Marks, F1
Bhisey, RA; Borges, A; Ramchandani, AG; Sirsat, SM1
Forbes, PD; Sambuco, CP1
Chang, RL; Conney, AH; Huang, MT; Uskokovic, M; Wood, AW1
Fujiki, H; Inui, N; Iwata, K; Ohkawa, Y; Shibuya, H1
Bhisey, RA; Ramchandani, AG; Sirsat, SM1
Fischer, SM; Gleason, GL; Nelson, K; Slaga, TJ1
Berry, DL; Fürstenberger, G; Marks, F; Sorg, B1
Boutwell, RK; Simsiman, RC; Takigawa, M; Verma, AK1
Barrett, JC; Gray, T; Sisskin, EE1
Goerttler, K; Hecker, E; Hesse, B; Loehrke, H; Schweitzer, J; Seip, H1
Hosoda, Y; Iseki, H; Kato, R; Nakadate, T; Sonoda, S; Takemura, S; Ura, A; Yamamoto, S1
Fürstenberger, G; Marks, F; Sorg, B1
Bhisey, RA; Borges, A; Iyengar, B; Ramchandani, AG; Sirsat, SM1
Astrup, EG; Iversen, OH1
Chouroulinkov, I; Coulomb, H; Grover, PL; MacNicoll, AD; Sims, P1
Belman, S2
Fischer, SM; Hardin, LG; Slaga, TJ1
Shoyab, M; Todaro, GJ; Warren, TC1
Chambers, DA; Krueger, GG; Shelby, J1
Bhisey, RA; Iyengar, B; Sirsat, SM1
Hecker, E; Schmidt, R1
Iversen, OH; Iversen, UM2
Fischer, SM; Mills, GD; Slaga, TJ1
Fürstenberger, G; Ganss, M; Marks, F; Seemann, D1
Brynes, PJ; Hecker, E; Schmidt, R1
Boutwell, RK; Verma, AK3
Iversen, OH; Paulsen, JE; Schjølberg, A1
Blumberg, PM; Driedger, PE2
Bohrman, JS; Fischer, SM; Gleason, GL; Slaga, TJ1
Boutwell, RK; Mueller, GC; Slaga, TJ; Verma, AK; Wertz, PW1
Fischer, SM; Gleason, GL; Mills, GD; Slaga, TJ1
Martel, N; Saint-Vincent, L; Yamasaki, H1
Boutwell, RK; Verma, AK; Weekes, RG1
Melchionne, S; Segal, A; Seidman, I; Smith, AC; Tseng, SS; Van Duuren, BL1
Bracken, WM; Gleason, GL; Hennings, H; Slaga, TJ; Weeks, CE1
Armuth, V; Berenblum, I1
Balmain, A; Hecker, E1
Boutwell, RK; Mufson, RA; Simsiman, RC1
Abb, J; Bayliss, GJ; Deinhardt, F1
Bertsch, S; Fürstenberger, G; Marks, F1
Boutwell, RK; Fischer, SM; Gleason, GL; Mufson, RA; Slaga, TJ; Verma, AK1
Fusenig, NE; Murray, AW1
Marks, F; Schweizer, J1
Bresnick, E; Lamden, M; Meunier, P1
Boutwell, RK; Rice, HM; Shapas, BG; Verma, AK2
Melchionne, SM; Smith, AC; Van Duuren, BL1
Maté, U; Melchionne, S; Segal, A; Seidman, I; Smith, A; Solomon, JJ; Van Duuren, BL1
Segal, A; Van Duuren, BL1
Boutwell, RK1
Scribner, JD; Slaga, TJ; Viaje, A1
Goerttler, K; Loehrke, H2
Alonso, A; Balmain, A; Fischer, J1
Slaga, TJ; Viaje, A; Weinstein, IB; Wigler, M1
Ben, T; Colburn, N; Hennings, H; Kelsey, W; Lichti, U; Patterson, E; Slaga, TJ; Yuspa, SH1
Bhisey, RA; Sirsat, SM1
Colburn, NH; Head, R; Lau, S1
Roop, DR; Toftgard, R; Yuspa, SH1
Parkinson, EK1
Fürstenberger, G; Marks, F; Schweizer, J1
Iversen, OH1
Glasø, M; Hovig, T; Iversen, OH; Ree, K1
Fujiki, H1
McCormick, DL; Moon, RC1
Colburn, NH; Gindhart, TD; Nakamura, Y1
Adams, LM; Fischer, SM1
Fujiki, H; Iwashima, A; Konishi, S; Nishino, H; Okabe, H; Okamoto, H; Shibata, S; Sugimura, T; Takizawa, H; Yoshioka, K1
Hakaim, AG; Jacoby, WT; O'Connell, JF; Weiss, HS1
Kato, R; Nakadate, T; Yamamoto, S1
Fürstenberger, G; Kinzel, V; Loehrke, H; Marks, F1
Gragtmans, NJ; Jevcak, JJ; Mitchel, RE; Morrison, DP1
Bowden, GT; Jaffe, DR1
Creasia, D; Kripke, ML; Strickland, PT1
Diwan, BA; Henneman, J; Ward, JM; Wenk, ML1
Agrawal, HP; Randerath, E; Randerath, K1
Boutwell, RK; Cleaveland, JS; Ordman, AB1
Autrup, H; Christensen, B; Skibshøj, I; Skouv, J1
Aldaz, CM; Conti, CJ; Gimenez, IB; Klein-Szanto, AJ; Slaga, TJ1
Marian, B; Mazzucco, K1
Fischer, SM; Hardin, L; Klein-Szanto, A; Slaga, TJ1
Loprinzi, CL; Verma, AK1
Kishore, GS; Perchellet, EM; Perchellet, JP1

Reviews

5 review(s) available for phorbols and Skin Neoplasms

ArticleYear
Observations on the mechanism of skin tumor promotion by phorbol esters.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Adenosylmethionine Decarboxylase; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; Eflornithine; Mice; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Protein Kinase C; Protein Kinases; Receptors, Drug; Receptors, Immunologic; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Phorbol ester receptors and the in vitro effects of tumor promoters.
    Annals of the New York Academy of Sciences, 1983, Volume: 407

    Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Mice; Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin Neoplasms; Structure-Activity Relationship

1983
Phorbol ester tumor promoters and lymphocyte proliferation.
    Cell biology international reports, 1983, Volume: 7, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Lymphocyte Activation; Lymphocytes; Mice; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1983
Multistage tumor promotion in skin.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; Humans; Mice; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1983
Defective responses of transformed keratinocytes to terminal differentiation stimuli. Their role in epidermal tumour promotion by phorbol esters and by deep skin wounding.
    British journal of cancer, 1985, Volume: 52, Issue:4

    Topics: Animals; Carcinogens; Cell Differentiation; Cell Transformation, Neoplastic; Epidermis; In Vitro Techniques; Keratins; Mice; Mitosis; Oncogenes; Papilloma; Peptides; Phenotype; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1985

Other Studies

117 other study(ies) available for phorbols and Skin Neoplasms

ArticleYear
A novel function of p38-regulated/activated kinase in endothelial cell migration and tumor angiogenesis.
    Molecular and cellular biology, 2012, Volume: 32, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma; Cell Movement; Cell Transformation, Neoplastic; Cytoskeleton; Disease Progression; Endothelial Cells; Focal Adhesion Protein-Tyrosine Kinases; Intracellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Neovascularization, Pathologic; Papilloma; Phorbols; Protein Serine-Threonine Kinases; Skin Neoplasms; Vascular Endothelial Growth Factor Receptor-2

2012
The tumorigenic and carcinogenic effect of TPA (12-0-tetradecanoylphorbol-13-acetate) when applied to the skin of BALB/cA mice.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1980, Volume: 33, Issue:3

    Topics: Animals; Carcinogens; Female; Male; Mice; Mice, Inbred BALB C; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1980
Decreased beta-adrenergic responsiveness in mouse epidermal papillomas during tumor promotion with phorbol myristate acetate.
    Cancer letters, 1980, Volume: 9, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Cyclic AMP; Female; Isoproterenol; Mice; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1980
Chemical carcinogenesis by the two-stage protocol in the skin Mastomys natalensis (Muridae) using topical initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-0-tetradecanoylphorbol-13-acetate.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1981, Volume: 38, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Keratoacanthoma; Male; Muridae; Neoplasms, Experimental; Phorbols; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1981
Effect of tumor promote phorbol esters on the in vitro keratinization of rat epidermal cells in normal, premalignant and malignant stages.
    Gan, 1981, Volume: 72, Issue:1

    Topics: Aneuploidy; Animals; Cell Differentiation; Cell Division; Cell Line; Diploidy; Embryo, Mammalian; Epidermal Cells; Epidermis; Keratins; Phorbol Esters; Phorbols; Precancerous Conditions; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate

1981
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on the biochemical processes linked to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1981, Volume: 41, Issue:10

    Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Cocarcinogenesis; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline

1981
Changes in regional keratin polypeptide patterns during phorbol ester-mediated reversible and permanently sustained hyperplasia of mouse epidermis.
    Cancer research, 1982, Volume: 42, Issue:4

    Topics: Animals; Back; Ear; Hyperplasia; Keratins; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tail

1982
Effect of hexachlorocyclohexane on diethylnitrosamine-induced hepatocarcinogenesis in rat and its failure to promote skin tumors on dimethylbenz[a]anthracene initiation in mouse.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Diethylnitrosamine; Drug Interactions; Female; gamma-Glutamyltransferase; Hexachlorocyclohexane; Liver; Liver Neoplasms, Experimental; Nitrosamines; Phorbols; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate

1984
Dehydroepiandrosterone (DHEA) and 3 beta-methylandrost-5-en-17-one: inhibitors of 7,12-dimethylbenz[a]anthracene (DMBA)-initiated and 12-O-tetradecanoylphorbol-13-acetate (TPA)-promoted skin papilloma formation in mice.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Androstenes; Animals; Benz(a)Anthracenes; Dehydroepiandrosterone; Drug Administration Schedule; Drug Antagonism; Estradiol; Female; Mice; Papilloma; Phorbols; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Uterus

1984
Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carboxy-Lyases; Cyclooxygenase Inhibitors; Female; Indomethacin; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Prostaglandins; Prostaglandins E, Synthetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1980
Can prenatal X-irradiation in mice act as an initiator stimulus in a modified 2-stage Berenblum/Mottram experiment with postnatal promotion with phorbol ester TPA?
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:2

    Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Cocarcinogenesis; Female; Fetus; Leukemia; Liver Neoplasms; Lung Neoplasms; Maternal-Fetal Exchange; Mice; Ovarian Diseases; Phorbols; Pregnancy; Prostaglandins; Radiation, Ionizing; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; X-Rays

1980
Effects of the phorbol ester 4-O-methyl-12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo: evidence for its uselessness as a negative control compound in studies on the biological effects of phorbol ester tumor promoters.
    Cancer research, 1982, Volume: 42, Issue:1

    Topics: Animals; Cell Division; Cocarcinogenesis; Cyclic AMP; Epidermis; Female; Growth Inhibitors; Indomethacin; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship

1982
Phorbol myristate acetate uncouples the relationship between beta-adrenergic receptors and adenyl cyclase in mouse epidermis: a phenotypic trait in papillomas.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Adenylyl Cyclases; Animals; Cocarcinogenesis; Cyclic GMP; Enzyme Activation; Epidermis; Isoproterenol; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
    Cancer research, 1982, Volume: 42, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1982
Binding of phorbol dibutyrate and epidermal growth factor to cultured human epidermal cells.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:3

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Epidermal Growth Factor; ErbB Receptors; Humans; Melanoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Interaction of epidermal growth factor with basal and differentiating epidermal cells of mice resistant and sensitive to carcinogenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:6

    Topics: Animals; Animals, Newborn; Calcium; Cell Differentiation; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Mice, Inbred Strains; Phorbols; Receptors, Cell Surface; Skin; Skin Neoplasms; Skin Physiological Phenomena; Species Specificity; Tetradecanoylphorbol Acetate

1984
Nature of the epidermal hyperplasia produced by mezerein, a weak tumor promoter, in initiated skin of mice.
    Cancer research, 1983, Volume: 43, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate

1983
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and ornithine decarboxylase activity by quercetin: possible involvement of lipoxygenase inhibition.
    Carcinogenesis, 1983, Volume: 4, Issue:10

    Topics: Animals; DNA; Epidermis; Female; Flavonoids; Lipoxygenase Inhibitors; Mice; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Quercetin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Skin tumor formation in the European hamster (Cricetus cricetus L.) after topical initiation with 7,12-dimethylbenz[a]anthracene (DMBA) and promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA).
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cricetinae; Drug Synergism; Female; Male; Neoplasms; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1984
Alteration in the distribution of the epidermal protein filaggrin during two-stage chemical carcinogenesis in the SENCAR mouse skin.
    Cancer research, 1984, Volume: 44, Issue:6

    Topics: Amino Acids; Animals; Epidermis; Female; Filaggrin Proteins; Fluorescent Antibody Technique; Immunodiffusion; Intermediate Filament Proteins; Male; Mice; Mice, Inbred Strains; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1984
Effects of flavonoids and antioxidants on 12-O-tetradecanoyl-phorbol-13-acetate-caused epidermal ornithine decarboxylase induction and tumor promotion in relation to lipoxygenase inhibition by these compounds.
    Gan, 1984, Volume: 75, Issue:3

    Topics: Animals; Antioxidants; Enzyme Induction; Epidermis; Female; Flavonoids; Lipoxygenase Inhibitors; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1984
Suppression of the first stage of phorbol 12-tetradecanoate 13-acetate-effected tumor promotion in mouse skin by nontoxic inhibition of DNA synthesis.
    Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:18

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; DNA Replication; Female; Hydroxyurea; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1984
DBA/2 mice are as sensitive as SENCAR mice to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
    Carcinogenesis, 1984, Volume: 5, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA; Female; Methylnitronitrosoguanidine; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Phorbols; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate

1984
Effect of 12-O-tetradecanoylphorbol-13-acetate on epithelial tumor induction in methylcholanthrene injected Swiss albino mice.
    Indian journal of experimental biology, 1983, Volume: 21, Issue:6

    Topics: Animals; Drug Synergism; Female; Methylcholanthrene; Mice; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Interactions of ultraviolet radiation, 12-O-tetradecanoyl-phorbol-13-acetate and retinoic acid in the skin of hairless mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1983, Volume: 21, Issue:5

    Topics: Animals; Carcinogens; Cocarcinogenesis; Epidermis; Male; Mice; Mice, Hairless; Mitosis; Neoplasms, Radiation-Induced; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Ultraviolet Rays

1983
1 alpha, 25-Dihydroxyvitamin D3 inhibits phorbol ester-dependent chemical carcinogenesis in mouse skin.
    Biochemical and biophysical research communications, 1983, Oct-31, Volume: 116, Issue:2

    Topics: Administration, Topical; Animals; Calcitriol; Female; Mice; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
A rapid, simple screening method for skin-tumor promoters using mouse peritoneal macrophages in vitro.
    Cancer letters, 1984, Volume: 21, Issue:3

    Topics: Animals; Carcinogens; Female; Macrophages; Mice; Mice, Inbred ICR; Nitroblue Tetrazolium; Phagocytosis; Phorbol Esters; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1984
Effects of 12-O-tetradecanoylphorbol-13-acetate on the incorporation of labelled precursors into RNA, DNA and protein in epidermis, dermis and subcutis from precancerous mouse skin with reference to enhanced tumorigenesis.
    Carcinogenesis, 1984, Volume: 5, Issue:2

    Topics: Animals; Carbon Radioisotopes; DNA Replication; Female; Kinetics; Leucine; Mice; Phorbols; Precancerous Conditions; Protein Biosynthesis; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Thymidine; Transcription, Genetic; Tritium; Uridine

1984
Two-stage tumorigenesis of dermal melanocytes in the back skin of the Syrian golden hamster using systemic initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1980, Volume: 40, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Cricetinae; Female; Melanocytes; Melanoma; Mesocricetus; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1980
Positive two-stage carcinogenesis in female Sprague-Dawley rats using 7,12-dimethylbenz(a)anthracene (dmba) as initiator and 12-o-tetradecanoylphorbol-13-acetate (tps) as promotor. Results of a pilot study.
    Virchows Archiv. A, Pathological anatomy and histology, 1980, Volume: 385, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Benz(a)Anthracenes; Castration; Cocarcinogenesis; Colonic Neoplasms; Female; Intestinal Neoplasms; Liver Neoplasms; Phorbols; Rats; Skin Neoplasms; Stomach; Stomach Neoplasms; Tetradecanoylphorbol Acetate

1980
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion.
    Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemical Phenomena; Chemistry; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate

1980
Two-stage skin carcinogenesis by systemic initiation of pregnant mice with 7,12-dimethylbenz(a)anthracene during gestation days 6-20 and postnatal promotion of the F 1-generation with the phorbol ester 12-tetradecanoylphorbol-13-acetate.
    Journal of cancer research and clinical oncology, 1980, Volume: 98, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Fetus; Gestational Age; Mice; Phorbols; Pregnancy; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1980
Skin tumor promotion by phorbol esters is a two-stage process.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:12

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Diterpenes; Female; Mice; Mitogens; Neoplasms, Experimental; Phorbol Esters; Phorbols; Prostaglandins; Skin Neoplasms; Structure-Activity Relationship; Terpenes

1981
Diterpene ester-mediated two-stage carcinogenesis.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cricetinae; Female; Guinea Pigs; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Milk; Neoplasms, Experimental; Phorbols; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vaginal Neoplasms

1982
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
    Biochemical and biophysical research communications, 1982, Apr-14, Volume: 105, Issue:3

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Antagonism; Eflornithine; Kinetics; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine; Tetradecanoylphorbol Acetate

1982
Correlation between sensitivity to tumor promotion and sustained epidermal hyperplasia of mice and rats treated with 12-O-tetra-decanoylphorbol-13-acetate.
    Carcinogenesis, 1982, Volume: 3, Issue:4

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Hyperplasia; Methylnitronitrosoguanidine; Mice; Mice, Inbred Strains; Phorbols; Rats; Rats, Inbred F344; Skin; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate

1982
7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoyl-phorbol-13-acetate-mediated skin tumor initiation and promotion in male Sprague-Dawley rats.
    Carcinogenesis, 1982, Volume: 3, Issue:7

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Diazonium Compounds; Male; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1982
Effect of the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and its nonpromoting analogue 4-O-methyl-TPA on dorsal dermal melanocytes of the Syrian golden hamster (Mesocricetus auratus).
    Journal of cancer research and clinical oncology, 1982, Volume: 103, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cricetinae; Female; Melanocytes; Melanoma; Mesocricetus; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Inhibition of 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion by nordihydroguaiaretic acid, a lipoxygenase inhibitor, and p-bromophenacyl bromide, a phospholipase A2 inhibitor.
    Gan, 1982, Volume: 73, Issue:6

    Topics: Acetophenones; Animals; Catechols; Enzyme Inhibitors; Female; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1982
Tumor promotion by phorbol esters in skin: evidence for a memory effect.
    Science (New York, N.Y.), 1983, Apr-01, Volume: 220, Issue:4592

    Topics: Animals; Carcinogens; Cell Line; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbol Esters; Phorbols; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1983
12-0-Tetradecanoylphorbol-13-acetate-induced amplification of mesenchymal tumorigenesis in the mouse skin.
    Journal of cancer research and clinical oncology, 1983, Volume: 105, Issue:1

    Topics: Animals; Cocarcinogenesis; Female; Methylcholanthrene; Mice; Mice, Inbred Strains; Phorbols; Sarcoma, Experimental; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1983
The tumourigenic and carcinogenic effect of 12-0-tetradecanoylphorbol-13-acetate when applied to the skin of BALB/cA and hairless (hr/hr) mice.
    Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, 1983, Volume: 91, Issue:2

    Topics: Amyloidosis; Animals; Female; Kupffer Cells; Male; Mice; Mice, Hairless; Mice, Inbred BALB C; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1983
Tumour-initiating activities of dihydrodiols of dibenz[a,c]anthracene.
    Cancer letters, 1983, Volume: 19, Issue:1

    Topics: Animals; Benz(a)Anthracenes; Female; Mice; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1983
Onion and garlic oils inhibit tumor promotion.
    Carcinogenesis, 1983, Volume: 4, Issue:8

    Topics: Animals; Cell Transformation, Neoplastic; Drug Antagonism; Female; Garlic; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oils; Phorbols; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Diazepam inhibition of phorbol ester tumor promotion.
    Cancer letters, 1983, Volume: 19, Issue:2

    Topics: Animals; Diazepam; Dose-Response Relationship, Drug; Female; Male; Mice; Papilloma; Phorbols; Sex Factors; Skin Neoplasms; Tetradecanoylphorbol Acetate

1983
Phorbol-12,13-diester 12-ester hydrolase may prevent tumour promotion by phorbol diesters in skin.
    Nature, 1982, Jan-14, Volume: 295, Issue:5845

    Topics: Animals; Carboxylic Ester Hydrolases; Cats; Child, Preschool; Cricetinae; Dogs; Female; Guinea Pigs; Humans; Kinetics; Macaca mulatta; Mice; Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rabbits; Rats; Skin Neoplasms; Species Specificity; Swine

1982
Epidermal proliferation of nude mouse skin, pig skin, and pig skin grafts. Failure of nude mouse skin to respond to the tumor promoter 12-O-tetradecanoyl phorbol 13-acetate.
    The Journal of experimental medicine, 1980, Nov-01, Volume: 152, Issue:5

    Topics: Animals; Mice; Mice, Nude; Neoplasms, Experimental; Phorbols; Skin; Skin Neoplasms; Skin Transplantation; Swine; Tetradecanoylphorbol Acetate; Transplantation Immunology; Transplantation, Heterologous

1980
Effect of the active tumor promoter, 12-O-tetradecanoylphorbol-13-acetate on hair follicular growth and development of hair anlage tumors in the mouse skin: a comparison with human adnexal lesions.
    Journal of cancer research and clinical oncology, 1982, Volume: 102, Issue:3

    Topics: Animals; Cocarcinogenesis; Epidermis; Female; Hair; Humans; Hyperplasia; Methylcholanthrene; Mice; Phorbols; Precancerous Conditions; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Simple phorbol esters as inhibitors of tumor promotion by TPA in mouse skin.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Epidermis; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1982
Must initiators come first? Tumorigenic and carcinogenic effects on skin of 3-methylcholanthrene and TPA in various sequences.
    British journal of cancer, 1982, Volume: 45, Issue:6

    Topics: Animals; Carcinoma; Cell Division; DNA; Drug Synergism; Hyperplasia; Methylcholanthrene; Mice; Mice, Hairless; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Inhibition of mouse skin tumor promotion by several inhibitors of arachidonic acid metabolism.
    Carcinogenesis, 1982, Volume: 3, Issue:11

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Animals; Arachidonic Acids; Biotransformation; Female; Male; Mice; Neoplasms, Experimental; Oxygenases; Papilloma; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin Antagonists; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Biological effects of phorbol ester tumor promoters in mouse skin.
    Progress in clinical and biological research, 1982, Volume: 102 pt A

    Topics: Animals; Cell Division; Hyperplasia; Kinetics; Mice; Neoplasms, Experimental; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1982
Plasminogen activator induction and platelet aggregation by phorbol and some of its derivatives: correlation with skin irritancy and tumor-promoting activity.
    Journal of cancer research and clinical oncology, 1980, Volume: 97, Issue:3

    Topics: Animals; Chick Embryo; Humans; Irritants; Mice; Phorbols; Plasminogen Activators; Platelet Aggregation; Skin; Skin Neoplasms; Structure-Activity Relationship

1980
Effect of butyric acid on tumor promotion: a correction.
    Cancer research, 1981, Volume: 41, Issue:9 Pt 1

    Topics: Animals; Butyrates; Mice; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1981
Characterization of arginase activity from mouse epidermis and its relation to ornithine decarboxylase induction by the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate.
    Biochimica et biophysica acta, 1981, Oct-12, Volume: 677, Issue:2

    Topics: Animals; Arginase; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Polyamines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1981
The time needed for normalization of hairless mouse epidermis after treatment with twice weekly topical skin applications of 10 nmol 12-O-tetradecanoylphorbol-13-acetate in acetone, or acetone alone, for 18 weeks. A morphologic and cell kinetic study.
    Carcinogenesis, 1981, Volume: 2, Issue:12

    Topics: Acetone; Animals; Cell Cycle; Female; Hyperplasia; Kinetics; Male; Mice; Mice, Inbred Strains; Phorbols; Skin; Skin Neoplasms; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate; Time Factors

1981
Structure-activity relationships in chick embryo fibroblasts for phorbol-related diterpene esters showing anomalous activities in vivo.
    Cancer research, 1980, Volume: 40, Issue:2

    Topics: Animals; Cells, Cultured; Chick Embryo; Deoxy Sugars; Deoxyglucose; Fibroblasts; Fibronectins; Inflammation; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1980
Prostaglandin enhancement of skin tumor initiation and promotion.
    Advances in prostaglandin and thromboxane research, 1980, Volume: 6

    Topics: Animals; Indomethacin; Mice; Neoplasms, Experimental; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Skin Neoplasms; Tetradecanoylphorbol Acetate

1980
Inhibition of skin tumor promotion by retinoic acid and its metabolite 5,6-epoxyretinoic acid.
    Cancer research, 1980, Volume: 40, Issue:7

    Topics: Animals; Female; Juvenile Hormones; Mice; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbol Esters; Phorbols; Skin Neoplasms; Time Factors; Tretinoin

1980
An organ culture of adult mouse skin: an in vitro model for studying the molecular mechanism of skin tumor promotion.
    Biochemical and biophysical research communications, 1980, Sep-30, Volume: 96, Issue:2

    Topics: Animals; Carboxy-Lyases; DNA; Enzyme Induction; Female; Indomethacin; Mice; Models, Biological; Neoplasms, Experimental; Organ Culture Techniques; Ornithine Decarboxylase; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1980
Indomethacin enhancement of TPA tumor promotion in mice.
    Cancer letters, 1980, Volume: 10, Issue:4

    Topics: Animals; Drug Synergism; Female; Flurbiprofen; Indomethacin; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1980
Long-term effect of a tumor promoter, 12-O-tetradecanoylphorbol-13-acetate, on induced differentiation of Friend leukemia cells.
    Cancer research, 1980, Volume: 40, Issue:10

    Topics: Acetamides; Animals; Cell Differentiation; Cells, Cultured; Cocarcinogenesis; Diamines; Friend murine leukemia virus; Leukemia, Experimental; Mice; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Virus Diseases

1980
Inhibition by putrescine of the induction of epidermal ornithine decarboxylase activity and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Cocarcinogenesis; Enzyme Induction; Epidermis; Mice; Ornithine Decarboxylase; Phorbols; Putrescine; Skin Neoplasms; Tetradecanoylphorbol Acetate

1980
The carcinogenic effect of TPA (12-0-tetradecanoylphorbol-13-acetate) when applied to the skin of hairless mice.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1979, May-04, Volume: 30, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Fibrosarcoma; Mice; Mice, Nude; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1979
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldehydes; Animals; Carcinoma, Squamous Cell; Decanoates; Drug Synergism; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1979
Inhibition of phorbol ester-induced tumor promotion in mice by vitamin A analog and anti-inflammatory steroid.
    Journal of the National Cancer Institute, 1979, Volume: 63, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Drug Synergism; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A

1979
Phorbol as a possible systemic promoting agent for skin carcinogenesis.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Jan-02, Volume: 85, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1976
On the biochemical mechanism of tumorigenesis in mouse skin. VII. The effects of tumor promoters on 3H-choline and 3H-glycerol incorporation into mouse epidermal phosphatidylcholine in relation to their effects on 3H-thymidine incorporation into DNA.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Aug-30, Volume: 86, Issue:3

    Topics: Animals; Choline; DNA, Neoplasm; Female; Glycerol; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phosphatidylcholines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1976
Increased cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in the epidermis of phorbol ester-treated mouse skin and in papillomas.
    Cancer research, 1979, Volume: 39, Issue:6 Pt 1

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Colchicine; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vinblastine

1979
Lymphocyte activation by the tumor-promoting agent 12-O-tetradecanoylphorbol-13-acetate (TPA).
    Journal of immunology (Baltimore, Md. : 1950), 1979, Volume: 122, Issue:5

    Topics: Animals; Callitrichinae; Dimethyl Sulfoxide; Dogs; Guinea Pigs; Haplorhini; Herpesvirus 4, Human; Humans; Lymphocyte Activation; Macaca mulatta; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred CBA; Mitogens; Pan troglodytes; Papio; Phorbols; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate

1979
Ornithine decarboxylase activity, cell proliferation, and tumor promotion in mouse epidermis in vivo.
    Cancer research, 1979, Volume: 39, Issue:10

    Topics: Animals; Carboxy-Lyases; Cell Division; Cyclic AMP; Female; Growth Inhibitors; Hyperplasia; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Physical Stimulation; Skin; Skin Neoplasms

1979
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.
    Cancer research, 1979, Volume: 39, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cyclic AMP; Dermatitis, Contact; Diterpenes; Female; Isoproterenol; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1979
Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters.
    Cancer letters, 1979, Volume: 7, Issue:2-3

    Topics: Animals; Binding Sites; Cells, Cultured; Epidermal Growth Factor; Mice; Neoplasms, Experimental; Peptides; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1979
Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hair; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate

1977
Epidermal prostaglandins after topical application of a tumor promotor.
    Cancer letters, 1979, Volume: 7, Issue:2-3

    Topics: Administration, Topical; Animals; Male; Mice; Neoplasms, Experimental; Phorbols; Prostaglandins E; Prostaglandins F; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1979
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis by vitamin A analogs (retinoids).
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Animals; Carboxy-Lyases; Drug Evaluation, Preclinical; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Polyamines; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Vitamin A

1978
Effect of aging in two-stage carcinogenesis on mouse skin with phorbol myristate acetate as promoting agent.
    Cancer research, 1978, Volume: 38, Issue:3

    Topics: Aging; Animals; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate

1978
Tumor-promoting activity of 2,3-dihydrophorbol myristate acetate and phorbolol myristate acetate in mouse skin.
    Cancer research, 1978, Volume: 38, Issue:4

    Topics: Animals; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1978
Non-phorbol mouse skin tumor promoters do not mimic phorbol myristate acetate in its effects on chick embryo fibroblasts.
    International journal of cancer, 1978, Jul-15, Volume: 22, Issue:1

    Topics: Acetates; Animals; Anthralin; Cantharidin; Carcinogens; Cell Membrane; Chick Embryo; Cytochalasin B; Deoxyglucose; Fibroblasts; Glycoproteins; Lauric Acids; Neoplasms, Experimental; Oleic Acids; Palmitic Acids; Phenols; Phorbols; Skin Neoplasms; Stearic Acids; Tetradecanoylphorbol Acetate

1978
Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.
    Cancer research, 1979, Volume: 39, Issue:2 Pt 1

    Topics: Animals; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A

1979
Inhibition of two-stage carcinogenesis in mouse skin with bis(2-chloroethyl)sulfide.
    Cancer research, 1976, Volume: 36, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred ICR; Mustard Compounds; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate

1976
The biochemistry of preneoplasia in mouse skin.
    Cancer research, 1976, Volume: 36, Issue:7 PT 2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Genes; Hyperplasia; Mice; Neoplasm Proteins; Papilloma; Phorbols; Precancerous Conditions; RNA, Neoplasm; Skin Neoplasms

1976
Epidermal cell proliferation and promoting ability of phorbol esters.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Hyperplasia; Inflammation; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1976
Diaplacental carcinogenesis: initiation with the carcinogens dimethylbenzanthracene (DMBA) and urethane during fetal life and postnatal promotion with the phorbol ester TPA in a modified 2-stage Berenblum/Mottram experiment.
    Virchows Archiv. A, Pathological anatomy and histology, 1976, Nov-22, Volume: 372, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Drug Synergism; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Phorbols; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane

1976
Improved tumour yields by means of a TPA-DMBA-TPA variation of the Berenrlum-Mottram experiment on the back skin of NMRI mice. The effect of stationary hyperplasia without inflammation.
    Experimentelle Pathologie, 1976, Volume: 12, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1976
Histone phosphorylation and synthesis of DNA and RNA during phases of proliferation and differentiation induced in mouse epidermis by the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.
    Cancer research, 1977, Volume: 37, Issue:5

    Topics: Animals; Cell Differentiation; Cell Division; DNA; DNA, Neoplasm; Female; Histones; Mice; Neoplasms, Experimental; Phorbols; Phosphorus; RNA; RNA, Neoplasm; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1977
Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activator.
    Cancer research, 1977, Volume: 37, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Cell Division; Cells, Cultured; Depression, Chemical; DNA; Female; Fluocinolone Acetonide; Fluocinonide; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Plasminogen Activators; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1977
Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.
    Cancer research, 1977, Volume: 37, Issue:7 Pt 1

    Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Administration Schedule; Enzyme Induction; Female; In Vitro Techniques; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A

1977
Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures.
    Nature, 1976, Jul-29, Volume: 262, Issue:5567

    Topics: Animals; Carboxy-Lyases; Carcinogens; Cells, Cultured; DNA; Enzyme Induction; Mice; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Structure-Activity Relationship

1976
Selective promoting activity of phorbol myristate acetate in experimental skin carcinogenesis.
    British journal of cancer, 1976, Volume: 34, Issue:6

    Topics: Animals; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Phorbols; Precancerous Conditions; Rhabdomyosarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1976
Decrease of epidermal histidase activity by tumor-promoting phorbol esters.
    Cancer research, 1975, Volume: 35, Issue:11 Pt 1

    Topics: Ammonia-Lyases; Animals; Benz(a)Anthracenes; Carcinogens; Depression, Chemical; Histidine Ammonia-Lyase; Male; Mice; Mice, Nude; Neoplasms, Experimental; Phorbols; Polysorbates; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane

1975
Keratin gene expression in mouse skin tumors and in mouse skin treated with 12-O-tetradecanoylphorbol-13-acetate.
    Cancer research, 1985, Volume: 45, Issue:11 Pt 2

    Topics: Animals; Carcinoma; Female; Fluocinolone Acetonide; Gene Expression Regulation; Keratins; Mice; Molecular Weight; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic

1985
Development of phorbol ester responsiveness in neonatal mouse epidermis: correlation between hyperplastic response and sensitivity to first-stage tumor promotion.
    Carcinogenesis, 1985, Volume: 6, Issue:2

    Topics: Animals; DNA; Female; Hyperplasia; Keratins; Mice; Mice, Inbred Strains; Mitosis; Ornithine Decarboxylase; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
TPA (12-O-tetradecanoyl-phorbol-13-acetate) as a carcinogen for mouse skin. A positive dose-response relationship.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1985, Volume: 49, Issue:2

    Topics: Animals; Carcinogens; Dose-Response Relationship, Drug; Mice; Mice, Inbred Strains; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
The influence of different fixatives and a tumor promoter, 12-0-tetradecanoyl-phorbol-13-acetate (TPA), on the induction of so-called dark cells in mouse epidermis. A light microscopical study.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1986, Volume: 50, Issue:4

    Topics: Acetone; Animals; Carcinogens; Cocarcinogenesis; Fixatives; Mice; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1986
[The actions of TPA-type as well as non-TPA type tumor promoters and their mechanism(s) in tumor promotion].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 2

    Topics: Acrylamides; Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cnidarian Venoms; Enzyme Activation; Humans; Lyngbya Toxins; Mice; Neoplasms, Experimental; Phorbols; Plant Extracts; Protein Kinase C; Receptors, Cell Surface; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thapsigargin

1986
Antipromotional activity of dietary N-(4-hydroxyphenyl)retinamide in two-stage skin tumorigenesis in CD-1 and SENCAR mice.
    Cancer letters, 1986, Volume: 31, Issue:2

    Topics: Animals; Carcinogens; Cocarcinogenesis; Diet; Drug Antagonism; Female; Fenretinide; Mice; Mice, Inbred Strains; Neoplasms, Multiple Primary; Phorbols; Skin Neoplasms; Species Specificity; Tetradecanoylphorbol Acetate; Tretinoin

1986
Role of reactive oxygen in tumor promotion: implication of superoxide anion in promotion of neoplastic transformation in JB-6 cells by TPA.
    Carcinogenesis, 1985, Volume: 6, Issue:2

    Topics: Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Hydroxides; Hydroxyl Radical; Lipoxygenase Inhibitors; Mannitol; Mice; Phorbols; Skin Neoplasms; Superoxide Dismutase; Superoxides; Tetradecanoylphorbol Acetate

1985
Suppression of tumor promoter-induced chemiluminescence in mouse epidermal cells by several inhibitors of arachidonic acid metabolism.
    Cancer research, 1985, Volume: 45, Issue:7

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Free Radicals; Lipoxygenase Inhibitors; Luminescent Measurements; Mice; Neutrophils; Phorbols; Skin; Skin Neoplasms; Superoxides; Tetradecanoylphorbol Acetate

1985
Glycyrrhetic acid inhibits tumor-promoting activity of teleocidin and 12-O-tetradecanoylphorbol-13-acetate in two-stage mouse skin carcinogenesis.
    Japanese journal of cancer research : Gann, 1986, Volume: 77, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; ErbB Receptors; Female; Glycyrrhetinic Acid; HeLa Cells; Lyngbya Toxins; Mice; Mice, Inbred ICR; Phorbols; Phospholipids; Phosphorus Radioisotopes; Quercetin; Receptors, Cell Surface; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate; Time Factors

1986
Inhibitory effect of toluene on tumor promotion in mouse skin.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 181, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Carcinogens; Cocarcinogenesis; Drug Antagonism; Male; Mice; Mice, Inbred C3H; Phorbols; Skin Neoplasms; Solvents; Tetradecanoylphorbol Acetate; Toluene

1986
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and epidermal ornithine decarboxylase activity in mouse skin by palmitoylcarnitine.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Animals; Calcium; Carnitine; Dose-Response Relationship, Drug; Egtazic Acid; Female; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Palmitoylcarnitine; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1986
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity and tumor promotion by N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) in mouse skin.
    Pharmacology, 1986, Volume: 32, Issue:3

    Topics: Animals; Calcium; Calmodulin; Enzyme Induction; Female; Lyngbya Toxins; Mice; Mice, Inbred Strains; Ornithine Decarboxylase; Papilloma; Phorbols; Protein Kinase C; Skin; Skin Neoplasms; Sulfonamides; Tetradecanoylphorbol Acetate

1986
[Factors controlling tumor promotion induced by TPA].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1986, Volume: 13, Issue:3 Pt 2

    Topics: Animals; Benzoquinones; Enzyme Activation; Lipoxygenase Inhibitors; Mice; Ornithine Decarboxylase; Palmitoylcarnitine; Papilloma; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Protein Kinase C; Quinones; Skin Neoplasms; Stimulation, Chemical; Tetradecanoylphorbol Acetate

1986
Three-stage tumorigenesis in mouse skin: DNA synthesis as a prerequisite for the conversion stage induced by TPA prior to initiation.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; DNA; Female; Hydroxyurea; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1986
Hyperthermia and phorbol ester tumor promotion in mouse skin.
    Carcinogenesis, 1986, Volume: 7, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Female; Hyperthermia, Induced; Mice; Papilloma; Phorbols; Skin; Skin Neoplasms; Skin Temperature; Tetradecanoylphorbol Acetate

1986
Ionizing radiation as an initiator in the mouse two-stage model of skin tumor formation.
    Radiation research, 1986, Volume: 106, Issue:2

    Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; X-Rays

1986
Enhancement of two-stage skin carcinogenesis by exposure of distant skin to UV radiation.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:5

    Topics: Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Fibrosarcoma; Immune Tolerance; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Ultraviolet Rays

1985
Effects of short-term exposure to the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate on skin carcinogenesis in SENCAR mice.
    Cancer letters, 1985, Volume: 26, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Female; Mice; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
12-O-tetradecanoylphorbol-13-acetate-induced rapid loss of persistent 7,12-dimethylbenz[a]anthracene-DNA adducts in mouse epidermis and dermis.
    Cancer letters, 1985, Volume: 27, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; DNA; Epidermis; Female; Mice; Mice, Inbred BALB C; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
12-O-tetradecanoylphorbol-13-acetate promotes tumors prior to initiation in two-stage promotion.
    Cancer letters, 1985, Volume: 29, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cocarcinogenesis; Diterpenes; Enzyme Induction; Female; Mice; Models, Biological; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate; Time Factors

1985
The skin tumor-promoter 12-O-tetradecanoylphorbol-13-acetate induces transcription of the c-fos proto-oncogene in human bladder epithelial cells.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Cells, Cultured; Epithelium; Humans; Phorbols; Proto-Oncogene Mas; Proto-Oncogenes; Skin Neoplasms; Tetradecanoylphorbol Acetate; Transcription, Genetic; Urinary Bladder

1986
Cutaneous changes during prolonged application of 12-O-tetradecanoylphorbol-13-acetate on mouse skin and residual effects after cessation of treatment.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Animals; Epidermis; Female; Hyperplasia; Mast Cells; Mice; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
Dermal collagen metabolism during tumor promotion with 12-O-tetradecanoylphorbol-13-acetate in mouse skin.
    Carcinogenesis, 1985, Volume: 6, Issue:4

    Topics: Animals; Collagen; Female; Hydroxyproline; Methylcholanthrene; Mice; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate

1985
Retinoyl-phorbol-acetate is a complete skin tumor promoter in SENCAR mice.
    Cancer letters, 1985, Volume: 27, Issue:3

    Topics: Animals; Female; Mice; Mice, Inbred Strains; Phorbol Esters; Phorbols; Skin Neoplasms; Species Specificity

1985
Dose and schedule of oral retinoic acid and indomethacin needed to effectively inhibit phorbol ester-induced epidermal ornithine decarboxylase activity.
    Carcinogenesis, 1985, Volume: 6, Issue:11

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Indomethacin; Male; Mice; Mice, Inbred Strains; Ornithine Decarboxylase Inhibitors; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin

1985
Enhancement by adriamycin of the effects of 12-O-tetradecanoylphorbol-13-acetate on mouse epidermal glutathione peroxidase activity, ornithine decarboxylase induction and skin tumor promotion.
    Cancer letters, 1985, Volume: 29, Issue:2

    Topics: Administration, Topical; Animals; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Enzyme Induction; Epidermis; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Mice; Ornithine Decarboxylase; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors

1985