phorbols has been researched along with Leukemia, Myeloid, Acute in 79 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 79 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Louache, F; Rochant, H; Testa, U; Thomopoulos, P; Titeux, M | 1 |
Bloch, A; Craig, RW | 1 |
Henning, CB; Huberman, E; Ryffel, B | 1 |
Bar-Eli, M; Koeffler, HP; Territo, M | 1 |
Baker, RD; Duncan, RA; Greenberger, JS; Hansen, SL; Newburger, PE | 1 |
Colburn, NH; Dalal, B; Gindhart, TD; Hegamyer, GA | 1 |
Cabot, MC | 2 |
Kato, R; Mita, S; Nakadate, T; Nakaki, T; Yamamoto, S | 1 |
Cuatrecasas, P; Jacobs, S; May, WS | 1 |
Harford, J; Klausner, RD; van Renswoude, J | 1 |
Besterman, JM; Cuatrecasas, P | 1 |
Estensen, RD; Mascioli, DW | 1 |
Block, A; Hromchak, R; Sakagami, H | 1 |
Nagasawa, K | 1 |
Minato, K; Minowada, J; Sagawa, K; Sugimoto, T; Takeda, K; Tatsumi, E | 1 |
Durham, JP; Fontana, JA; Ruppert, M | 1 |
Abrams, SI; Brahmi, Z; Bray, RA | 1 |
Griffin, J; Kufe, DW; Mitchell, T; Shafman, T | 1 |
Palù, G | 1 |
Dowdle, EB; Jacobs, P; Wilson, EL | 1 |
Decal, DL; Whittington, KB; Zucker, RM | 1 |
Cohen, LE; Koeffler, HP; Lehrer, RI | 1 |
Anderson, NL; Callaham, MF; Gemmell, MA; Huberman, E; Murao, S | 1 |
Cooper, HL; Feuerstein, N | 4 |
Fibach, E; Kornberg, A; Rachmilewitz, EA; Treves, A | 1 |
Cabot, MC; Lackey, RJ | 1 |
Kitagawa, S; Miura, Y; Ohta, M; Saito, M; Takaku, F | 1 |
Au, WW; Callaham, MF; Huberman, E; Workman, ML | 1 |
Luikart, SD; Maniglia, CA; Sartorelli, AC | 1 |
AbdAllah, NA; Fisch, H; Flick, DA; Gifford, GE | 1 |
Okabe, N; Saito, H; Suzuki, R; Yamada, K | 1 |
Kato, R; Mita, S; Nakaki, T; Yamamoto, S | 1 |
Anderson, WB; Cooper, HL; Feuerstein, N; Sahai, A; Salomon, DS | 1 |
Agranat, I; Fibach, E; Rachmilewitz, EA | 1 |
Abbott, RE; Callaham, MF; Fisher, PB; Huberman, E; Schachter, D | 1 |
Iijima, S; Koike, K; Minami, S; Namikawa, R; Nishida, K; Ogata, S; Ota, K; Suchi, T; Takahashi, T; Tsuge, I; Ueda, R | 1 |
Litcofsky, PB; Moore, MA; Ralph, P; Williams, N | 1 |
Braslawsky, GR; Callaham, M; Fugiki, H; Huberman, E | 1 |
Hoffman, DR; Huberman, E | 1 |
Abrahm, J; Cooper, RA; Lange, B; Levis, A; Meo, P; Pegoraro, L; Rovera, G | 1 |
Acs, G; Christman, JK; Gilbert, HS; Mendelsohn, N | 1 |
Greenberger, JS; Newburger, PE; Sakakeeny, M | 1 |
Chang, LJ; McCulloch, EA | 1 |
Bar-Eli, M; Koeffler, HP; Territo, MC | 1 |
Fibach, E; Rachmilewitz, EA | 1 |
Callaham, M; Herrmann, A; Huberman, E; Slaga, T; Weeks, C | 1 |
Callaham, M; Huberman, E; Slaga, TJ; Solanki, V | 1 |
Cassileth, PA; Cooper, RA; Suholet, D | 1 |
Cooper, RA; Cossu, G; Kuo, AL; Pessano, S; Warren, L | 1 |
Abrams, T; Griffin, JD; Nadler, LM; Ritz, J; Schlossman, SF; Todd, RF | 1 |
Callaham, M; Huberman, E; Slaga, T; Solanki, V; Weeks, C | 1 |
Honma, Y; Hozumi, M; Kasukabe, T | 1 |
Bloch, A; Minowada, J; Takeda, K | 1 |
Galili, U; Gamliel, H; Gurfel, D; Korkesh, A; Leizerowitz, R; Polliack, A | 1 |
Abraham, S; Bottero, L; Ferrero, D; Lebman, D; Pagliardi, GL; Pessano, S; Rovera, G; Vartikar, J | 1 |
Diamond, L; O'Brien, TG; Rovera, G | 1 |
Haddox, MK; Maddox, AM | 1 |
Besterman, JM; Cragoe, EJ; Cuatrecasas, P; LeVine, H; May, WS | 1 |
Caldwell, AB; Kreutter, D; Morin, MJ | 1 |
Cuatrecasas, P; Jacobs, S; May, WS; Sahyoun, N; Wolf, M | 1 |
Andoh, T; Gatanaga, T; Kitahara, N; Morioka, H; Murata, M; Shibai, H; Soma, G | 1 |
Connolly, NL; Senior, RM; Welgus, HG | 1 |
Bell, RM; Ebeling, JG; Ganong, BR; Kuhn, LJ; Niedel, JE; Vandenbark, GR | 1 |
Cooper, HL; Feuerstein, N; Nishikawa, M | 1 |
Sugihara, H; Yun, K | 1 |
Macfarlane, DE | 1 |
Luikart, SD | 1 |
Center, MS; Marsh, W | 1 |
Gazitt, Y; Gurfel, D; Leizerowitz, R; Or, R; Polliack, A | 1 |
Abrahm, JL; Cassileth, PA; Cooper, RA; Gerson, SL; Hoxie, JA; Tannenbaum, SH | 1 |
Fukuda, M; Siebert, PD | 1 |
Anderson, NL; Coussens, PM; Gemmell, MA; Huberman, E; Murao, S | 1 |
Bowers, CH; Den, T; Svet-Moldavsky, IA; Wroblesky, H | 1 |
Clarkson, B; Gulati, SC; Svet-Moldavsky, I | 1 |
Cooper, HL; Feuerstein, N; Monos, DS | 1 |
1 review(s) available for phorbols and Leukemia, Myeloid, Acute
Article | Year |
---|---|
[Effect of tumor promotor on neoplastic cell transformation].
Topics: Animals; Carcinogens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Guinea Pigs; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Mice; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1983 |
78 other study(ies) available for phorbols and Leukemia, Myeloid, Acute
Article | Year |
---|---|
Effect of phorbol esters on iron uptake in human hematopoietic cell lines.
Topics: Biological Transport; Calcifediol; Calcitriol; Cell Line; Dimethyl Sulfoxide; Heme; Humans; Iron; Iron Radioisotopes; Kinetics; Leukemia, Myeloid, Acute; Phorbol Esters; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transferrin; Tretinoin | 1984 |
Early decline in c-myb oncogene expression in the differentiation of human myeloblastic leukemia (ML-1) cells induced with 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Cell Division; DNA Replication; Electrophoresis, Agar Gel; Gene Expression Regulation; Humans; Leukemia, Myeloid, Acute; Nucleic Acid Hybridization; Oncogenes; Phorbols; RNA; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Differentiation of human T-lymphoid leukemia cells into cells that have a suppressor phenotype is induced by phorbol 12-myristate 13-acetate.
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Phorbols; T-Lymphocytes, Regulatory; Tetradecanoylphorbol Acetate | 1982 |
Phorbol diester-induced macrophage differentiation of leukemic blasts from patients with human myelogenous leukemia.
Topics: Cell Adhesion; Cell Differentiation; Histocytochemistry; Humans; Leukemia, Myeloid, Acute; Macrophages; Muramidase; Naphthol AS D Esterase; Nitroblue Tetrazolium; Peroxidase; Phagocytosis; Phorbols; Sodium Fluoride; Tetradecanoylphorbol Acetate | 1980 |
Functionally deficient differentiation of HL-60 promyelocytic leukemia cells induced by phorbol myristate acetate.
Topics: Cell Differentiation; Complement System Proteins; Humans; Leukemia, Myeloid, Acute; Macrophages; Nucleotidases; Oxygen Consumption; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
The role of phorbol ester receptor binding in responses to promoters by mouse and human cells.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Differentiation; Cell Line; Clone Cells; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin; Tetradecanoylphorbol Acetate | 1983 |
Effect of cellular phospholipid modification on phorbol diester binding.
Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phospholipids; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tritium | 1983 |
Inhibition by palmitoylcarnitine of adhesion and morphological changes in HL-60 cells induced by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Caenorhabditis elegans Proteins; Carnitine; Carrier Proteins; Cell Adhesion; Cell Line; Drug Antagonism; Humans; Kinetics; Leukemia, Myeloid, Acute; Palmitoylcarnitine; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1984 |
Association of phorbol ester-induced hyperphosphorylation and reversible regulation of transferrin membrane receptors in HL60 cells.
Topics: Carcinogens; Cell Line; Cell Membrane; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphorylation; Receptors, Cell Surface; Receptors, Transferrin; Transferrin | 1984 |
Rapid internalization of the transferrin receptor in K562 cells is triggered by ligand binding or treatment with a phorbol ester.
Topics: Biological Transport; Cell Line; Cell Membrane; Humans; Iron; Iron Radioisotopes; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1984 |
Phorbol esters rapidly stimulate amiloride-sensitive Na+/H+ exchange in a human leukemic cell line.
Topics: Amiloride; Carrier Proteins; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Pyrazines; Sodium-Hydrogen Exchangers; Tetradecanoylphorbol Acetate | 1984 |
Analysis of human promyelocytic leukemia cell (HL60) variants insensitive to phorbol ester tumor promoters.
Topics: Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Genetic Variation; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1984 |
Prevention of phorbol ester receptor down modulation in human myeloblastic leukemia ML-1 cells by differentiation-stimulating serum components.
Topics: Animals; Binding, Competitive; Blood; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cattle; Cell Differentiation; Cell Line; Culture Media; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug | 1984 |
Modulation of cell surface antigens induced by 12-O-tetradecanoyl-phorbol 13-acetate in two myeloblastic cell lines, a promyelocytic cell line, and a monoblastic cell line: detection with five monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Adhesion; Cell Line; Cell Membrane; Fluorescent Antibody Technique; Humans; Kinetics; Leukemia, Monocytic, Acute; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Glycosyltransferase activities and the differentiation of human promyelocytic (HL60) cells by retinoic acid and a phorbol ester.
Topics: Cell Differentiation; Cell Line; Fucosyltransferases; Galactosyltransferases; Hexosyltransferases; Humans; Kinetics; Leukemia, Myeloid, Acute; Neuraminidase; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1983 |
Mechanism of action of phorbol myristate acetate on human natural killer cell activity.
Topics: Calcimycin; Cell Adhesion; Cell Line; Cytochalasins; Cytotoxicity, Immunologic; Humans; Killer Cells, Natural; Kinetics; Leukemia, Myeloid, Acute; Mycotoxins; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Polyamine requirements for induction of HL-60 promyelocyte differentiation by leukocyte-conditioned medium and phorbol ester.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Line; Culture Media; Eflornithine; Humans; Kinetics; Leukemia, Myeloid, Acute; Leukocytes; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Spermidine; Tetradecanoylphorbol Acetate | 1984 |
[The effect of 12-O-tetradecanoylphorbol-13-acetate on acute myeloid leukemia cells obtained directly from the patient. Failure of the compound to induce a "true" maturation].
Topics: Cells, Cultured; Humans; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
The effects of dexamethasone and tetradecanoyl phorbol acetate on plasminogen activator release by human acute myeloid leukemia cells.
Topics: Cell Survival; Cells, Cultured; Dexamethasone; DNA; Granulocytes; Humans; Leukemia, Myeloid, Acute; Phorbols; Plasminogen Activators; Tetradecanoylphorbol Acetate | 1983 |
The effect of glutathione on HL-60 treated with dimethylsulfoxide, butyric acid or 12-O-tetradecanoylphorbol-13-acetate.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Dimethyl Sulfoxide; Glutathione; Humans; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Specific binding of [3H]phorbol dibutyrate to phorbol diester-responsive and -resistant clones of a human myeloid leukemia (KG-1) line 1.
Topics: Cell Differentiation; Cell Line; Clone Cells; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols | 1983 |
Control of macrophage cell differentiation in human promyelocytic HL-60 leukemia cells by 1,25-dihydroxyvitamin D3 and phorbol-12-myristate-13-acetate.
Topics: Antibodies, Monoclonal; Calcitriol; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Rapid protein phosphorylation induced by phorbol ester in HL-60 cells. Unique alkali-stable phosphorylation of a 17,000-dalton protein detected by two-dimensional gel electrophoresis.
Topics: Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Molecular Weight; Phorbols; Phosphorylation; Proteins; Tetradecanoylphorbol Acetate | 1983 |
Generation of procoagulant activity (PCA) by macrophage-like cells derived from acute and chronic myeloid leukaemia cells in response to phorbol esters.
Topics: Adolescent; Adult; Aged; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Cell Differentiation; Cell Separation; Cells, Cultured; Child; Child, Preschool; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Middle Aged; Monocytes; Phorbols; Reference Values; Tetradecanoylphorbol Acetate | 1983 |
Acetate utilization and fatty acid metabolism in phorbol ester and dimethyl sulfoxide-differentiated human leukemia cells.
Topics: Acetates; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; Fatty Acids; Granulocytes; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
[Differentiation induction of acute leukemia cells and its clinical usefulness].
Topics: Adolescent; Adult; Aged; Cell Differentiation; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Double minute chromatin bodies and other chromosome alterations in human myeloid HL-60 leukemia cells susceptible or resistant to induction of differentiation by phorbol-12-myristate-13-acetate.
Topics: Cell Differentiation; Cell Line; Chromatin; Chromosome Aberrations; Chromosome Banding; Chromosome Disorders; Drug Resistance; Humans; Karyotyping; Leukemia, Myeloid, Acute; Muramidase; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Rapid phosphorylation-dephosphorylation of specific proteins induced by phorbol ester in HL-60 cells. Further characterization of the phosphorylation of 17-kilodalton and 27-kilodalton proteins in myeloid leukemic cells and human monocytes.
Topics: Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Myeloid, Acute; Molecular Weight; Monocytes; Neoplasm Proteins; Phorbols; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Tetradecanoylphorbol Acetate | 1984 |
Studies of the differentiation of promyelocytic cells by phorbol ester. II. A methylation inhibitor, 3-deazaadenosine, inhibits the induction of specific differentiation proteins. Lack of effect on early and late phosphorylation events.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Cell Movement; Electrophoresis, Polyacrylamide Gel; Humans; Isomerism; Kinetics; Leukemia, Myeloid, Acute; Membrane Proteins; Molecular Weight; Phorbols; Phosphorylation; Ribonucleosides; Tetradecanoylphorbol Acetate; Tubercidin | 1984 |
Studies of the differentiation of promyelocytic cells by phorbol ester. I. Induction of discrete membrane proteins characteristic of monocytes and expression of motility functions in HL-60 cells following differentiation by phorbol ester.
Topics: Cell Differentiation; Cell Line; Cell Movement; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Myeloid, Acute; Lymphocytes; Macrophages; Membrane Proteins; Molecular Weight; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Glycosaminoglycan synthesis during differentiation of HL60/HGPRT-leukemia cells induced by dimethyl sulfoxide and 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Glycosaminoglycans; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1984 |
Production of a cytotoxin from phorbol myristate acetate-treated human promyelocytes.
Topics: Animals; Cell Line; Cytotoxins; Dactinomycin; Embryo, Mammalian; Fibroblasts; HeLa Cells; Humans; Kinetics; L Cells; Leukemia, Myeloid, Acute; Mice; Phorbols; Skin; Skin Physiological Phenomena; Tetradecanoylphorbol Acetate | 1984 |
[Induction of differentiation of human myelomonocytic cell lines by chemical inducers: analysis of surface antigens with monoclonal antibodies].
Topics: Antibodies, Monoclonal; Antigens, Surface; Cell Differentiation; Cell Line; Cells, Cultured; Granulocytes; Humans; Leukemia, Myeloid, Acute; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1984 |
Tumor promoting phorbol diesters: substrates for diacylglycerol lipase.
Topics: Animals; Carbon Radioisotopes; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Lipoprotein Lipase; Male; Phorbols; Phospholipids; Rats; Substrate Specificity; Tetradecanoylphorbol Acetate; Tritium | 1984 |
Phosphorylation and dephosphorylation of human promyelocytic leukemia cell (HL-60) proteins by tumor promoter.
Topics: Autoradiography; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Molecular Weight; Neoplasm Proteins; Phorbols; Phosphorylation; Subcellular Fractions; Tetradecanoylphorbol Acetate | 1984 |
Differential phosphorylation events associated with phorbol ester effects on acceleration versus inhibition of cell growth.
Topics: Animals; Blood Platelets; Carcinoma, Squamous Cell; Cell Division; Cell Line; Cells, Cultured; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Mice; Mice, Inbred Strains; Molecular Weight; Phorbols; Phosphoproteins; Phosphorylation; Proteins; Skin; Tetradecanoylphorbol Acetate | 1984 |
Differentiation of human myeloid leukemic cells by phorbol esters: correlation with tumor promotion.
Topics: Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Diterpenes; Drug Interactions; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbol Esters; Phorbols; Retinoids; Structure-Activity Relationship; Terpenes | 1984 |
Membrane lipid dynamics in human promyelocytic leukemia cells sensitive and resistant to 12-O-tetradecanoylphorbol-13-acetate induction of differentiation.
Topics: Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Drug Resistance; Fluorescence Polarization; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Membrane Fluidity; Membrane Lipids; Muramidase; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Serological analysis of cell surface antigens of HL-60 cells before and after treatment with a phorbol ester tumor promoter.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Blood Platelets; Cell Line; Cell Membrane; Humans; Leukemia, Myeloid, Acute; Microscopy, Electron; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1983 |
Induction of antibody-dependent and nonspecific tumor killing in human monocytic leukemia cells by nonlymphocyte factors and phorbol ester.
Topics: Antibody-Dependent Cell Cytotoxicity; Cell Line; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Phagocytosis; Phorbols; Receptors, Complement; Receptors, Fc; Tetradecanoylphorbol Acetate; Urinary Bladder Neoplasms | 1982 |
Induction of differentiation of human promyelocytic leukemia (HL-60) cells by teleocidin and phorbol-12-myristate-13-acetate.
Topics: Alkaloids; Carcinogens; Cell Differentiation; Cells, Cultured; DNA, Neoplasm; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
The control of phospholipid methylation by phorbol diesters in differentiating human myeloid HL-60 leukemia cells.
Topics: Alkaloids; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Lyngbya Toxins; Methylation; Methyltransferases; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphatidylethanolamine N-Methyltransferase; Phospholipids; Tetradecanoylphorbol Acetate | 1982 |
Differentiation of human leukemias in response to 12-0-tetradecanoylphorbol-13-acetate in vitro.
Topics: Cell Adhesion; Cell Aggregation; Cell Transformation, Neoplastic; Esterases; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Phagocytosis; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Effect of maturation on the response of human promyelocytic leukemia cells (HL-60) to the tumor promoter 12-o-tetradecanolyphorbol-13-acetate.
Topics: Cell Differentiation; Fibrinolysis; Hexosephosphates; Humans; Intracellular Membranes; Leukemia, Myeloid, Acute; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxygen Consumption; Phorbols; Plasminogen; Receptors, Complement; Receptors, Drug; Tetradecanoylphorbol Acetate | 1980 |
Phorbol myristate acetate stimulates macrophage differentiation and replication and alters granulopoiesis and leukemogenesis in long-term bone marrow cultures.
Topics: Animals; Bone Marrow Cells; Cell Differentiation; Cells, Cultured; Granulocytes; Hematopoiesis; Leukemia, Myeloid, Acute; Macrophages; Mice; Phorbols; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Time Factors | 1980 |
Dose-dependent effects of a tumor promotor on blast cell progenitors in human myeloblastic leukemia.
Topics: Cells, Cultured; Clone Cells; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Phorbol ester effect on differentiation of human myeloid leukemia cell lines blocked at different stages of maturation.
Topics: Blood Bactericidal Activity; Cell Adhesion; Cell Differentiation; Cell Division; Chemotaxis, Leukocyte; Humans; Leukemia, Myeloid, Acute; Lysosomes; Macrophages; Phagocytosis; Phorbol Esters; Phorbols; Receptors, Fc | 1981 |
Tumour promoters induce macrophage differentiation in human myeloid cells from patients with acute and chronic myelogenous leukaemia.
Topics: Bone Marrow; Cell Differentiation; Cells, Cultured; Diterpenes; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Spleen; Tetradecanoylphorbol Acetate | 1981 |
Alterations in polyamine levels induced by phorbol diesters and other agents that promote differentiation in human promyelocytic leukemia cells.
Topics: Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Muramidase; Phorbol Esters; Phorbols; Polyamines; Putrescine; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1981 |
Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells.
Topics: Binding Sites; Binding, Competitive; Carcinogens; Cell Differentiation; Cell Line; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Early changes in phosphatidylcholine metabolism in human acute promyelocytic leukemia cells stimulated to differentiate by phorbol ester.
Topics: Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid, Acute; Methylation; Phorbol Esters; Phorbols; Phosphatidylcholines; Phospholipids; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Decreased synthesis of high-molecular-weight glycopeptides in human promyelocytic leukemic cells (HL-60) during phorbol ester-induced macrophage differentiation.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Chromatography, DEAE-Cellulose; Chromatography, Gel; Glycopeptides; Granulocytes; Humans; Leukemia, Myeloid, Acute; Lymphocytes; Macrophages; Membrane Proteins; Molecular Weight; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Expression of normal monocyte-macrophage differentiation antigens on HL60 promyelocytes undergoing differentiation induced by leukocyte-conditioned medium or phorbol diester.
Topics: Antigens, Surface; Cell Differentiation; Cell Line; Culture Media; Leukemia, Myeloid, Acute; Leukocytes; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1981 |
Cell differentiation, alterations in polyamine levels, and specific binding of phorbol diesters in cultured human cells.
Topics: Binding Sites; Carcinogens; Cell Differentiation; Cell Line; Cell Membrane; Humans; Leukemia, Myeloid, Acute; Melanoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Polyamines; Tetradecanoylphorbol Acetate | 1982 |
Modification by serum of differentiation of cultured human myeloid leukemia cells in response to 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Blood Physiological Phenomena; Cells, Cultured; Culture Media; Humans; Leukemia, Experimental; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Kinetics of appearance of differentiation-associated characteristics in ML-1, a line of human myeloblastic leukemia cells, after treatment with 12-O-tetradecanoylphorbol-13-acetate, dimethyl sulfoxide or 1-beta-D-arabinofuranosylcytosine.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Cell Survival; Dimethyl Sulfoxide; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Tetradecanoylphorbol Acetate; Vidarabine | 1982 |
Exposure to phorbol diester (TPA) in vitro as an aid in the classification of blasts in human myelogenous and lymphoid leukemias: in vitro differentiation, growth patterns, and ultrastructural observations.
Topics: Histocytochemistry; Humans; In Vitro Techniques; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Leukocytes; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Induction of differentiation of human myeloid leukemias by phorbol diesters: phenotypic changes and mode of action.
Topics: Animals; Antibodies, Monoclonal; Binding Sites; Cell Differentiation; Cell Division; Cell Line; Cell Membrane; Humans; Interphase; Leukemia, Experimental; Leukemia, Myeloid, Acute; Phenotype; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Transferrin | 1982 |
Induction of differentiation in human promyelocytic leukemia cells by tumor promoters.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Diterpenes; Humans; Leukemia, Myeloid, Acute; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Transglutaminase activity increases in HL60 cells induced to differentiate with retinoic acid and TPA but not with DMSO.
Topics: Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate; Time Factors; Transglutaminases; Tretinoin | 1985 |
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.
Topics: Amiloride; Carrier Proteins; Cell Adhesion; Cell Differentiation; Cell Line; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Phosphorylation; Protein Kinase C; Protein Kinase Inhibitors; Pyrazines; Receptors, Cell Surface; Receptors, Transferrin; Sodium-Hydrogen Exchangers | 1985 |
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.
Topics: Cell Differentiation; Cell Division; Cell Line; Diglycerides; Enzyme Activation; Humans; Leukemia, Myeloid, Acute; Neoplasm Proteins; Phorbols; Phosphatidylcholines; Phosphorylation; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate | 1985 |
Mechanism of phorbol diester-induced regulation of surface transferrin receptor involves the action of activated protein kinase C and an intact cytoskeleton.
Topics: Cell Line; Cytoskeleton; Humans; Kinetics; Leukemia, Myeloid, Acute; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Transferrin; Tetradecanoylphorbol Acetate; Transferrin | 1985 |
Detection of a countertranscript in promyelocytic leukemia cells HL60 during early differentiation by TPA.
Topics: Base Sequence; Cell Differentiation; Cell Line; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Restriction Enzymes; Humans; Leukemia, Myeloid, Acute; Nucleic Acid Hybridization; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate; Time Factors; Transcription, Genetic | 1985 |
12-o-Tetradecanoyl-phorbol-13-acetate-differentiated U937 cells express a macrophage-like profile of neutral proteinases. High levels of secreted collagenase and collagenase inhibitor accompany low levels of intracellular elastase and cathepsin G.
Topics: Cathepsin G; Cathepsins; Cell Differentiation; Cell Line; Chemotaxis; Cholecalciferol; Cyclic AMP; DNA; Humans; Leukemia, Myeloid, Acute; Macrophages; Microbial Collagenase; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Phorbols; Serine Endopeptidases; Tetradecanoylphorbol Acetate | 1986 |
Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Diglycerides; Enzyme Activation; Glycerides; Humans; Leukemia, Myeloid, Acute; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Drug; Receptors, Immunologic | 1985 |
Cell-free system studies on the phosphorylation of the 17,000-20,000 dalton protein induced by phorbol ester in human leukemic cells and evidence for a similar event in virally transformed murine fibroblasts.
Topics: Animals; Cell Line; Cell Transformation, Viral; Cell-Free System; Cytosol; Fibroblasts; Humans; Kirsten murine sarcoma virus; Leukemia, Myeloid, Acute; Mice; Molecular Weight; Neoplasm Proteins; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Trypsin | 1985 |
Cell differentiation and cell cycle effects on human promyelocytic leukemia cells induced by 12-O-tetradecanoylphorbol-13-acetate.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Flow Cytometry; Histocytochemistry; Humans; Isoenzymes; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Mitosis; Nitroblue Tetrazolium; Oxidation-Reduction; Phagocytosis; Phenotype; Phorbols; Receptors, Fc; Tetradecanoylphorbol Acetate | 1986 |
Phorbol diester-induced phosphorylation of nuclear matrix proteins in HL60 promyelocytes. Possible role in differentiation studied by cationic detergent gel electrophoresis.
Topics: Antigens, Nuclear; Autoantibodies; Autoradiography; Cell Adhesion; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Leukemia, Myeloid, Acute; Nucleoproteins; Phorbols; Phosphorus Radioisotopes; Phosphorylation; Tetradecanoylphorbol Acetate | 1986 |
Inability of HL-60 cells induced by phorbol myristate acetate to produce macrophage-associated glycosaminoglycans.
Topics: Cell Line; Glycosaminoglycans; Humans; Kinetics; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate | 1986 |
Dimethylsulfoxide, retinoic acid and 12-O-tetradecanoylphorbol-13-acetate induce a selective decrease in the phosphorylation of P150, a surface membrane phosphoprotein of HL60 cells resistant to adriamycin.
Topics: Dimethyl Sulfoxide; Doxorubicin; Drug Resistance; Electrophoresis, Polyacrylamide Gel; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinases; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |
Hairy cell leukaemia: effects of phorbol ester on cell morphology and adherence and comparison with other B-cell neoplasias.
Topics: B-Lymphocytes; Cell Adhesion; Humans; Leukemia, Hairy Cell; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphoma; Microscopy, Electron; Microscopy, Electron, Scanning; Phorbols; Tetradecanoylphorbol Acetate | 1986 |
Differential effects of phorbol esters on normal myeloid precursors and leukemic cells: basis for autologous bone marrow reconstitution in acute nonlymphocytic leukemia using phorbol ester-treated bone marrow from patients in remission.
Topics: Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cell Cycle; Cell Differentiation; Cells, Cultured; Colony-Forming Units Assay; Combined Modality Therapy; Dose-Response Relationship, Drug; Freezing; Hematopoiesis; Humans; Karyotyping; Leukemia; Leukemia, Myeloid, Acute; Phorbols; Preservation, Biological; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Regulation of glycophorin gene expression by a tumor-promoting phorbol ester in human leukemic K562 cells.
Topics: Cell Line; Genes; Glucosamine; Glycophorins; Humans; Kinetics; Leukemia, Myeloid, Acute; Methionine; Molecular Weight; Phorbols; Sialoglycoproteins; Sulfur Radioisotopes; Tetradecanoylphorbol Acetate; Tritium | 1985 |
Specific protein phosphorylation in human promyelocytic HL-60 leukemia cells susceptible or resistant to induction of cell differentiation by phorbol-12-myristate-13-acetate.
Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line; Drug Resistance; Humans; Leukemia, Myeloid, Acute; Molecular Weight; Neoplasm Proteins; Phorbols; Phosphoproteins; Phosphorylation; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Tetradecanoylphorbol Acetate | 1985 |
Multiplication of human fetal myelomonocytic precursors in medium conditioned by acute myelocytic leukemia cells treated by 12-O-tetradecanoyl phorbol 13-acetate (TPA).
Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Colony-Forming Units Assay; Culture Media; Culture Techniques; Fetus; Granulocytes; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid, Acute; Macrophages; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Growth of human bone marrow in vitro.
Topics: Bone Marrow Cells; Cell Division; Cells, Cultured; Colony-Stimulating Factors; Culture Media; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Macrophages; Monocytes; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
Phorbol ester effect in platelets, lymphocytes, and leukemic cells (HL-60) is associated with enhanced phosphorylation of class I HLA antigens. Coprecipitation of myosin light chain.
Topics: Blood Platelets; Cell Line; Electrophoresis, Polyacrylamide Gel; HLA Antigens; Humans; Immunosorbent Techniques; Leukemia, Myeloid, Acute; Lymphocytes; Phorbols; Phosphorylation; Tetradecanoylphorbol Acetate | 1985 |