phorbols has been researched along with Experimental Neoplasms in 108 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 108 (100.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Hatano, M; Ishiguro, H; Ogura, H; Takimoto, T; Umeda, R | 1 |
Reyes-Mayes, D; Volm, M; Wayss, K | 1 |
Colletta, G; Di Fiore, PP; Ferrentino, M; Pietropaolo, C; Turco, MC; Vecchio, G | 1 |
Boutwell, RK; Perchellet, JP | 1 |
Schweizer, J; Winter, H | 1 |
Bleackley, RC; Havele, C; Horak, H; McElhaney, J; Paetkau, VH; Shaw, AR; Turner, AR | 1 |
Braun, SJ; Marko, M; Parsons, DF; Wansor, KJ | 1 |
Dokhelar, MC; Garson, D; Tabilio, A; Testa, U; Tursz, T; Vainchenker, W; Wakasugi, H | 1 |
Ashendel, CL; Boutwell, RK; Verma, AK | 1 |
Ludwig, KW; Niles, RM | 1 |
Salomon, DS | 1 |
Argyris, TS; Fürstenberger, G; Marks, F; Richter, H | 1 |
Belman, S; Garte, SJ | 1 |
Brostrom, CO; Brostrom, MA; Brotman, LA; Geller, HM; Lee, C; Wolff, DJ | 1 |
Boutwell, RK; Conrad, EA; Verma, AK | 1 |
Abutbul, H; Rotter, V; Wolf, D | 1 |
Blumberg, PM; Delclos, KB; Dunn, JA; Jaken, S; Leach, KL; Yeh, E | 1 |
Daniel, LW; Kucera, LS; Waite, M | 1 |
Klein-Szanto, A; Nettesheim, P; Terzaghi, M | 1 |
Argyris, TS | 1 |
Kirch, ME; Miller, RA; Palladino, MA; Pearlstein, KT; Pelus, LM; Staiano-Coico, L; Stutman, O | 1 |
Bash, JA; Baxter, CS; Fish, LA | 1 |
Goerttler, K; Hesse, B; Loehrke, H; Schweizer, J | 4 |
Curtis, GL; Heidrick, ML; Ryan, WL; Stenback, F | 1 |
Fischer, SM; Gleason, GL; Nelson, K; Slaga, TJ | 1 |
Nettesheim, P; Topping, DC | 1 |
Goerttler, K; Hesse, B; Loehrke, H; Milz, A; Schweizer, J | 1 |
Berry, DL; Fürstenberger, G; Marks, F; Sorg, B | 1 |
Boutwell, RK; Simsiman, RC; Takigawa, M; Verma, AK | 1 |
Lindquist, RR; Munger, WE | 1 |
Hosoda, Y; Iseki, H; Kato, R; Nakadate, T; Sonoda, S; Takemura, S; Ura, A; Yamamoto, S | 1 |
Fürstenberger, G; Marks, F; Sorg, B | 1 |
Chouroulinkov, I; Coulomb, H; Grover, PL; MacNicoll, AD; Sims, P | 1 |
Belman, S | 1 |
Boone, CW; Scott, RE | 1 |
Shoyab, M; Todaro, GJ; Warren, TC | 1 |
Hilfiker, ML; Laufer, TM; Piacentini, MJ; Sando, JJ | 1 |
Bash, JA; Baxter, CS; Ferguson, TA; Fish, LA; Michael, JG | 1 |
Forbes, IJ; Valente, L; Zalewski, PD | 1 |
Chambers, DA; Krueger, GG; Shelby, J | 1 |
Blumberg, PM | 1 |
Hecker, E; Keist, R; Keller, R; Köppel, P | 1 |
Elkind, MM; Han, A | 1 |
Diamond, L; O'Brien, TG; Saladik, D | 1 |
Hecker, E; Schmidt, R | 1 |
Currens, M; Iype, PT; Ray-Chaudhuri, R | 1 |
Bennett, M; Fredrickson, GG | 1 |
Anderson, WB; Cooper, HL; Kraft, AS; Sando, JJ | 1 |
Fischer, SM; Mills, GD; Slaga, TJ | 1 |
Fürstenberger, G; Ganss, M; Marks, F; Seemann, D | 1 |
Marchok, AC; Nettesheim, P; Steele, VE | 1 |
Boutwell, RK; Verma, AK | 3 |
Colburn, NH; De Luca, LM; Dion, LD | 1 |
Blumberg, PM; Driedger, PE | 2 |
Blumberg, PM; Delclos, KB; Nagle, DS | 1 |
Bohrman, JS; Fischer, SM; Gleason, GL; Slaga, TJ | 1 |
Fischer, SM; Gleason, GL; Mills, GD; Slaga, TJ | 1 |
Bias, NE; Helson, L; Kopelovich, L | 1 |
Melchionne, S; Segal, A; Seidman, I; Smith, AC; Tseng, SS; Van Duuren, BL | 1 |
Bracken, WM; Gleason, GL; Hennings, H; Slaga, TJ; Weeks, CE | 1 |
Nettesheim, P; Terzaghi, M | 1 |
Armuth, V; Berenblum, I | 2 |
Balmain, A; Hecker, E | 1 |
Goerttler, K; Löhrke, H | 1 |
Boutwell, RK; Mufson, RA; Simsiman, RC | 1 |
Bertsch, S; Fürstenberger, G; Marks, F | 1 |
Boutwell, RK; Fischer, SM; Gleason, GL; Mufson, RA; Slaga, TJ; Verma, AK | 1 |
Fusenig, NE; Murray, AW | 1 |
Yamasaki, H | 1 |
Chouroulinkov, I; Gentil, A; Lasne, C | 1 |
Marks, F; Schweizer, J | 1 |
Griesemer, RA; Nelson, FR; Nettesheim, P; Pal, BC; Topping, DC | 1 |
Bresnick, E; Lamden, M; Meunier, P | 1 |
Fisher, PB; Mufson, RA; Weinstein, IB | 1 |
Adolf, W; Armuth, V; Berenblum, I; Hecker, E; Opferkuch, HJ; Schmidt, R; Sorg, B | 1 |
Keller, R | 1 |
Boutwell, RK; Rice, HM; Shapas, BG; Verma, AK | 2 |
Melchionne, SM; Smith, AC; Van Duuren, BL | 1 |
Maté, U; Melchionne, S; Segal, A; Seidman, I; Smith, A; Solomon, JJ; Van Duuren, BL | 1 |
Berry, DL; Bracken, WM; Fischer, SM; Slaga, TJ; Viaje, A | 1 |
Pienta, RJ; Poiley, JA; Raineri, R | 1 |
Segal, A; Van Duuren, BL | 1 |
Scribner, JD; Slaga, TJ; Viaje, A | 1 |
Goerttler, K; Loehrke, H | 2 |
Chang, CC; Chu, EH; Trosko, JE; Yotti, LP | 1 |
Alonso, A; Balmain, A; Fischer, J | 1 |
Slaga, TJ; Viaje, A; Weinstein, IB; Wigler, M | 1 |
Bhisey, RA; Sirsat, SM | 1 |
Colburn, NH; Head, R; Lau, S | 1 |
Johnson, HM; Torres, BA | 1 |
Abrahamsson, L; Esscher, T; Jergil, B; Mattsson, M; Påhlman, S; Ruusala, AI | 1 |
Fujiki, H | 1 |
Katunuma, N; Kido, H | 1 |
Adams, DO; Somers, SD | 1 |
Naroditskiĭ, BS; Ponomarev, TI; Potebnia, GP; Struk, VI; Tikhonenko, TI | 1 |
Bowden, GT; Jaffe, DR | 1 |
Adams, DO; Dean, JH; Lauer, LD; Luebke, RW; Luster, MI; Murray, MJ | 1 |
Buzhievskaia, TI; Bykorez, AI; Kononenko, LI; Lukash, LL; Shapiro, NI | 1 |
Gibbs, NK; Magnus, IA; Young, AR | 1 |
3 review(s) available for phorbols and Experimental Neoplasms
Article | Year |
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Phorbol ester receptors and the in vitro effects of tumor promoters.
Topics: Animals; Caenorhabditis elegans Proteins; Carrier Proteins; Mice; Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Skin Neoplasms; Structure-Activity Relationship | 1983 |
In vitro studies on the mode of action of the phorbol esters, potent tumor promoters, part 2.
Topics: Animals; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Clone Cells; DNA Repair; Models, Biological; Mutagens; Mutation; Neoplasms, Experimental; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1981 |
[Tumor promotion in chemical carcinogenesis-inhibition of cell differentiation by phorbol esters (author's transl)].
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Depression, Chemical; Drug Resistance; Globins; Leukemia, Experimental; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; RNA, Messenger | 1979 |
105 other study(ies) available for phorbols and Experimental Neoplasms
Article | Year |
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Effects of chemical inducers on the Epstein-Barr virus cycle in epithelial/nasopharyngeal carcinoma hybrid cell line.
Topics: Butyrates; Cell Line; Herpesvirus 4, Human; Humans; Hydrogen Peroxide; Nasopharyngeal Neoplasms; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1984 |
Chemical carcinogenesis by the two-stage protocol in the skin Mastomys natalensis (Muridae) using topical initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-0-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Female; Keratoacanthoma; Male; Muridae; Neoplasms, Experimental; Phorbols; Skin Diseases; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Enhancement of viral gene expression in Friend erythroleukemic cells by 12-O tetradecanoylphorbol-13-acetate.
Topics: Cell Differentiation; Clone Cells; Dimethyl Sulfoxide; Friend murine leukemia virus; Genes, Viral; Leukemia, Erythroblastic, Acute; Neoplasms, Experimental; Phorbols; Plasminogen Activators; RNA-Directed DNA Polymerase; RNA, Viral; Tetradecanoylphorbol Acetate | 1980 |
Effects of 3-isobutyl-1-methylxanthine and cyclic nucleotides on the biochemical processes linked to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 1-Methyl-3-isobutylxanthine; Administration, Topical; Animals; Cocarcinogenesis; Cyclic AMP; Cyclic GMP; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Theophylline | 1981 |
Changes in regional keratin polypeptide patterns during phorbol ester-mediated reversible and permanently sustained hyperplasia of mouse epidermis.
Topics: Animals; Back; Ear; Hyperplasia; Keratins; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tail | 1982 |
Translation of lymphocyte mRNA for mouse colony stimulating factor.
Topics: Animals; Cell Line; Colony-Stimulating Factors; Lymphocyte Activation; Lymphocytes; Lymphoma; Mice; Neoplasms, Experimental; Phorbols; Poly A; Protein Biosynthesis; RNA; RNA, Messenger; Tetradecanoylphorbol Acetate | 1983 |
"Dark cells" in normal, hyperplastic, and promoter-treated mouse epidermis studied by conventional and high-voltage electron microscopy.
Topics: Aging; Animals; Epidermal Cells; Epidermis; Female; Hyperplasia; Mice; Microscopy, Electron; Neoplasms, Experimental; Phorbols; Pregnancy; Staining and Labeling; Tetradecanoylphorbol Acetate | 1983 |
K562 cells induced to differentiate by phorbol ester tumor promotors resist NK lysis.
Topics: Cell Differentiation; Cells, Cultured; Humans; Immunity, Innate; Interferons; Killer Cells, Natural; Neoplasm Proteins; Neoplasms, Experimental; Phorbol Esters; Phorbols; RNA, Messenger; Tetradecanoylphorbol Acetate | 1984 |
Inhibition by prostaglandin synthesis inhibitors of the induction of epidermal ornithine decarboxylase activity, the accumulation of prostaglandins, and tumor promotion caused by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carboxy-Lyases; Cyclooxygenase Inhibitors; Female; Indomethacin; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Prostaglandins; Prostaglandins E, Synthetic; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Suppression of cyclic AMP-dependent protein kinase activity in murine melanoma cells by 12-0-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cells, Cultured; Cyclic AMP; Kinetics; Melanins; Melanoma; Mice; Neoplasms, Experimental; Phorbols; Protein Kinase Inhibitors; Saccharin; Tetradecanoylphorbol Acetate | 1980 |
Inhibition of epidermal growth factor binding to mouse embryonal carcinoma cells by phorbol esters mediated by specific phorbol ester receptors.
Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Epidermal Growth Factor; ErbB Receptors; Kinetics; Mice; Neoplasms, Experimental; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Teratoma; Tetradecanoylphorbol Acetate | 1981 |
Effects of the phorbol ester 4-O-methyl-12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo: evidence for its uselessness as a negative control compound in studies on the biological effects of phorbol ester tumor promoters.
Topics: Animals; Cell Division; Cocarcinogenesis; Cyclic AMP; Epidermis; Female; Growth Inhibitors; Indomethacin; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship | 1982 |
Phorbol myristate acetate uncouples the relationship between beta-adrenergic receptors and adenyl cyclase in mouse epidermis: a phenotypic trait in papillomas.
Topics: Adenylyl Cyclases; Animals; Cocarcinogenesis; Cyclic GMP; Enzyme Activation; Epidermis; Isoproterenol; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Receptors, Adrenergic; Receptors, Adrenergic, beta; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Alterations of glial tumor cell Ca2+ metabolism and Ca2+-dependent cAMP accumulation by phorbol myristate acetate.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Biological Transport, Active; Calcium; Cell Line; Cholera Toxin; Cyclic AMP; Glioma; Kinetics; Neoplasms, Experimental; Norepinephrine; Phorbols; Rats; Tetradecanoylphorbol Acetate; Trifluoperazine | 1982 |
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Flavonoids; Injections, Intraperitoneal; Methylcholanthrene; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1982 |
The presence of p53 transformation-related protein in Ab-MuLV transformed cells is required for their development into lethal tumors in mice.
Topics: Abelson murine leukemia virus; Animals; Cell Line; Cell Transformation, Neoplastic; Cocarcinogenesis; Female; Leukemia Virus, Murine; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbols; Phosphoproteins; Tetradecanoylphorbol Acetate; Tumor Suppressor Protein p53 | 1983 |
12-O-tetradecanoyl-phorbol-13-acetate enhancement of the tumorigenic potential of herpes simplex virus type 2 transformed cells.
Topics: Animals; Cell Division; Cell Transformation, Viral; Cocarcinogenesis; Neoplasms, Experimental; Phorbols; Rats; Simplexvirus; Tetradecanoylphorbol Acetate | 1983 |
Effect of the promoter 12-O-tetradecanoylphorbol-13-acetate on the evolution of carcinogen-altered cell populations in tracheas initiated with 7,12-dimethylbenz(a)anthracene.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Division; Female; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1983 |
Nature of the epidermal hyperplasia produced by mezerein, a weak tumor promoter, in initiated skin of mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Diterpenes; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1983 |
Multiple lymphokine production by a phorbol ester-stimulated mouse thymoma: relationship to cell cycle events.
Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Cell Cycle; Flow Cytometry; Interferon-gamma; Lymphokines; Mice; Neoplasms, Experimental; Phenotype; Phorbols; Rats; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1983 |
Parallel orders of reactivity in murine cells of mezerein and phorbol esters toward the mixed-lymphocyte response and promotion of tumorigenesis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Diterpenes; Lymphocyte Culture Test, Mixed; Lymphocytes; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Terpenes | 1981 |
Two-stage tumorigenesis of dermal melanocytes in the back skin of the Syrian golden hamster using systemic initiation with 7,12-dimethylbenz(a)anthracene and topical promotion with 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Cricetinae; Female; Melanocytes; Melanoma; Mesocricetus; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Autoantibody and tumor promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antibody Formation; Autoantibodies; Croton Oil; Female; Mice; Mice, Inbred A; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1980 |
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Chemical Phenomena; Chemistry; Cocarcinogenesis; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Terpenes; Tetradecanoylphorbol Acetate | 1980 |
Promotion-like enhancement of tracheal carcinogenesis in rats by 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Dose-Response Relationship, Drug; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Tracheal Neoplasms | 1980 |
Diaplacental initiation of NMRI mice with 7,12-dimethylbenz[a]anthracene during gestation days 6--20 and postnatal treatment of the F1-generation with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate: tumor incidence in organs other than the skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Female; Gestational Age; Mice; Neoplasms, Experimental; Phorbols; Pregnancy; Prenatal Exposure Delayed Effects; Sex Factors; Tetradecanoylphorbol Acetate | 1981 |
Skin tumor promotion by phorbol esters is a two-stage process.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Diterpenes; Female; Mice; Mitogens; Neoplasms, Experimental; Phorbol Esters; Phorbols; Prostaglandins; Skin Neoplasms; Structure-Activity Relationship; Terpenes | 1981 |
Diterpene ester-mediated two-stage carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Cricetinae; Female; Guinea Pigs; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Milk; Neoplasms, Experimental; Phorbols; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vaginal Neoplasms | 1982 |
Polyamine biosynthesis and skin tumor promotion: inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha-difluoromethylornithine.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Antagonism; Eflornithine; Kinetics; Mice; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Phorbols; Polyamines; Putrescine; Skin; Skin Neoplasms; Spermidine; Spermine; Tetradecanoylphorbol Acetate | 1982 |
7,12-Dimethylbenz[a]anthracene/12-O-tetradecanoyl-phorbol-13-acetate-mediated skin tumor initiation and promotion in male Sprague-Dawley rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinogens; Cocarcinogenesis; Diazonium Compounds; Male; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred Strains; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Effect of phorbol esters on alloimmune cytolysis.
Topics: Animals; Cell Survival; Cytotoxicity, Immunologic; Lymphoma; Mast-Cell Sarcoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbols; T-Lymphocytes; Tetradecanoylphorbol Acetate | 1982 |
Inhibition of 12-O-tetradecanoyl-phorbol-13-acetate-induced tumor promotion by nordihydroguaiaretic acid, a lipoxygenase inhibitor, and p-bromophenacyl bromide, a phospholipase A2 inhibitor.
Topics: Acetophenones; Animals; Catechols; Enzyme Inhibitors; Female; Lipoxygenase Inhibitors; Masoprocol; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1982 |
Tumor promotion by phorbol esters in skin: evidence for a memory effect.
Topics: Animals; Carcinogens; Cell Line; Epidermis; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Phorbol Esters; Phorbols; Precancerous Conditions; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1983 |
Tumour-initiating activities of dihydrodiols of dibenz[a,c]anthracene.
Topics: Animals; Benz(a)Anthracenes; Female; Mice; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1983 |
Onion and garlic oils inhibit tumor promotion.
Topics: Animals; Cell Transformation, Neoplastic; Drug Antagonism; Female; Garlic; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Oils; Phorbols; Plants, Medicinal; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1983 |
PRomotion of smooth surface tumorigenicity by phorbol myristate acetate in Balb/3T3 cells and Balb/3T3 T proadipocytes.
Topics: Animals; Cell Differentiation; Cell Line; Cocarcinogenesis; Embryo, Mammalian; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1981 |
Phorbol-12,13-diester 12-ester hydrolase may prevent tumour promotion by phorbol diesters in skin.
Topics: Animals; Carboxylic Ester Hydrolases; Cats; Child, Preschool; Cricetinae; Dogs; Female; Guinea Pigs; Humans; Kinetics; Macaca mulatta; Mice; Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Rabbits; Rats; Skin Neoplasms; Species Specificity; Swine | 1982 |
Identification of phorbol ester receptors in T-cell growth factor-producing and -nonproducing EL4 mouse thymoma cells.
Topics: Animals; Binding, Competitive; Cell Line; Interleukin-2; Kinetics; Lymphokines; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Receptors, Mitogen; T-Lymphocytes; Thymoma; Thymus Neoplasms | 1982 |
Effects of tumor-promoting agents on cells of the murine immune system: inhibition of antibody synthesis and of macrophage-mediated tumor cell cytotoxicity.
Topics: Animals; Antibody Formation; B-Lymphocytes; Cytotoxicity, Immunologic; Female; Macrophages; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Human B-lymphocyte maturation sequence revealed by TPA-induced differentiation of leukaemic cells.
Topics: B-Lymphocytes; Cell Differentiation; Cells, Cultured; Humans; Leukemia, Lymphoid; Neoplasms, Experimental; Phorbols; Receptors, Immunologic; Rosette Formation; Tetradecanoylphorbol Acetate | 1982 |
Epidermal proliferation of nude mouse skin, pig skin, and pig skin grafts. Failure of nude mouse skin to respond to the tumor promoter 12-O-tetradecanoyl phorbol 13-acetate.
Topics: Animals; Mice; Mice, Nude; Neoplasms, Experimental; Phorbols; Skin; Skin Neoplasms; Skin Transplantation; Swine; Tetradecanoylphorbol Acetate; Transplantation Immunology; Transplantation, Heterologous | 1980 |
Suppression of natural tumor resistance by tumor promoters.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Lymphokines; Macrophage Activation; Macrophage-Activating Factors; Macrophages; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate | 1982 |
Enhanced transformation of mouse 10T1/2 cells by 12-O-tetradecanoylphorbol-13-acetate following exposure to X-rays or to fission-spectrum neutrons.
Topics: Animals; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cocarcinogenesis; Fast Neutrons; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Neutrons; Phorbols; Radiation Dosage; Tetradecanoylphorbol Acetate; X-Rays | 1982 |
Effects of tumor-promoting phorbol diesters on neoplastic progression of Syrian hamster embryo cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Embryo, Mammalian; Mesocricetus; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Polyamines; Precancerous Conditions; Tetradecanoylphorbol Acetate | 1982 |
Simple phorbol esters as inhibitors of tumor promotion by TPA in mouse skin.
Topics: Animals; Cocarcinogenesis; DNA; Dose-Response Relationship, Drug; Epidermis; Female; Hyperplasia; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1982 |
Enhancement of sister-chromatid exchanges by tumour promoters.
Topics: Animals; Cell Cycle; Cell Line; Crossing Over, Genetic; Deoxyglucose; Dose-Response Relationship, Drug; Neoplasms, Experimental; Phenobarbital; Phorbols; Saccharin; Sister Chromatid Exchange; Tetradecanoylphorbol Acetate | 1982 |
Suppression of the cytotoxic response of mouse lymphocytes to syngeneic tumor cells by tumor-promoting phorbol ester.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Female; Killer Cells, Natural; Lymphoma; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Multiple Myeloma; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1982 |
Decrease in cytosolic calcium/phospholipid-dependent protein kinase activity following phorbol ester treatment of EL4 thymoma cells.
Topics: Animals; Calcium; Cell Line; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phospholipids; Protein Kinases; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thymoma; Thymus Neoplasms | 1982 |
Inhibition of mouse skin tumor promotion by several inhibitors of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Animals; Arachidonic Acids; Biotransformation; Female; Male; Mice; Neoplasms, Experimental; Oxygenases; Papilloma; Phorbols; Phospholipases; Phospholipases A; Phospholipases A2; Prostaglandin Antagonists; Pyrazoles; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Biological effects of phorbol ester tumor promoters in mouse skin.
Topics: Animals; Cell Division; Hyperplasia; Kinetics; Mice; Neoplasms, Experimental; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1982 |
Enhancement of carcinogenesis in cultured respiratory tract epithelium by 12-0-tetradecanoylphorbol-13-acetate.
Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Epithelium; Female; Methylnitronitrosoguanidine; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms | 1980 |
Characterization of arginase activity from mouse epidermis and its relation to ornithine decarboxylase induction by the tumor-promoting agent, 12-O-tetradecanoylphorbol-13-acetate.
Topics: Animals; Arginase; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Polyamines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1981 |
Phorbol ester-induced anchorage independence and its antagonism by retinoic acid correlates with altered expression of specific glycoproteins.
Topics: Animals; Carcinogens; Cell Adhesion; Cells, Cultured; Gene Expression Regulation; Glycoproteins; Mice; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Tretinoin | 1981 |
Structure-activity relationships in chick embryo fibroblasts for phorbol-related diterpene esters showing anomalous activities in vivo.
Topics: Animals; Cells, Cultured; Chick Embryo; Deoxy Sugars; Deoxyglucose; Fibroblasts; Fibronectins; Inflammation; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1980 |
Specific binding of phorbol ester tumor promoters to mouse skin.
Topics: Animals; Binding, Competitive; Epidermis; Kinetics; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Receptors, Drug; Skin; Structure-Activity Relationship | 1980 |
Prostaglandin enhancement of skin tumor initiation and promotion.
Topics: Animals; Indomethacin; Mice; Neoplasms, Experimental; Phorbols; Prostaglandins; Prostaglandins E; Prostaglandins F; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
An organ culture of adult mouse skin: an in vitro model for studying the molecular mechanism of skin tumor promotion.
Topics: Animals; Carboxy-Lyases; DNA; Enzyme Induction; Female; Indomethacin; Mice; Models, Biological; Neoplasms, Experimental; Organ Culture Techniques; Ornithine Decarboxylase; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin | 1980 |
Indomethacin enhancement of TPA tumor promotion in mice.
Topics: Animals; Drug Synergism; Female; Flurbiprofen; Indomethacin; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1980 |
Tumour promoter alone induces neoplastic transformation of fibroblasts from humans genetically predisposed to cancer.
Topics: Animals; Cell Adhesion; Cell Transformation, Neoplastic; Eye; Humans; Mice; Mice, Nude; Multiple Endocrine Neoplasia; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Systemic two-stage carcinogenesis in the epithelium of the forestomach of mice using 7,12-dimethylbenz(a)anthracene as initiator and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate as promoter.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cocarcinogenesis; Drug Synergism; Epithelium; Female; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Phorbols; Stomach Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Effects of structural changes on the tumor-promoting activity of phorbol myristate acetate on mouse skin.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aldehydes; Animals; Carcinoma, Squamous Cell; Decanoates; Drug Synergism; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1979 |
Inhibition of phorbol ester-induced tumor promotion in mice by vitamin A analog and anti-inflammatory steroid.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cocarcinogenesis; Drug Synergism; Female; Fluocinolone Acetonide; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vitamin A | 1979 |
Dynamics of neoplastic development in carcinogen-exposed tracheal mucosa.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Cell Adhesion; Cells, Cultured; Epithelium; Female; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Tetradecanoylphorbol Acetate; Time Factors; Trachea; Tracheal Neoplasms; Transplantation, Isogeneic | 1979 |
Phorbol as a possible systemic promoting agent for skin carcinogenesis.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Drug Synergism; Female; Injections, Intraperitoneal; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
On the biochemical mechanism of tumorigenesis in mouse skin. VII. The effects of tumor promoters on 3H-choline and 3H-glycerol incorporation into mouse epidermal phosphatidylcholine in relation to their effects on 3H-thymidine incorporation into DNA.
Topics: Animals; Choline; DNA, Neoplasm; Female; Glycerol; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Phosphatidylcholines; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Diaplacental carcinogenesis: tumor localization and tumor incidence in NMRI mice after diaplacental initiation with DMBA and urethane and postnatal promotion and the phorbol ester TPA in a modified 2-stage Berenblum/Mottram experiment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Abortion, Spontaneous; Administration, Oral; Administration, Topical; Animals; Benz(a)Anthracenes; Female; Genital Neoplasms, Female; Injections, Intraperitoneal; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Neoplasms, Multiple Primary; Organ Specificity; Phorbols; Pregnancy; Tetradecanoylphorbol Acetate; Urethane | 1977 |
Increased cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in the epidermis of phorbol ester-treated mouse skin and in papillomas.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Colchicine; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Vinblastine | 1979 |
Ornithine decarboxylase activity, cell proliferation, and tumor promotion in mouse epidermis in vivo.
Topics: Animals; Carboxy-Lyases; Cell Division; Cyclic AMP; Female; Growth Inhibitors; Hyperplasia; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbol Esters; Phorbols; Physical Stimulation; Skin; Skin Neoplasms | 1979 |
Tritiated thymidine as a broad spectrum initiator in transplacental two-stage carcinogenesis, with phorbol as promoter.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phorbol Esters; Phorbols; Pregnancy; Thymidine; Tritium | 1979 |
Effects of 12-O-tetradecanoylphorbol-13-acetate and mezerein on epidermal ornithine decarboxylase activity, isoproterenol-stimulated levels of cyclic adenosine 3':5'-monophosphate, and induction of mouse skin tumors in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Cyclic AMP; Dermatitis, Contact; Diterpenes; Female; Isoproterenol; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Binding of epidermal growth factor to primary and permanent cultures of mouse epidermal cells: inhibition by tumor-promoting phorbol esters.
Topics: Animals; Binding Sites; Cells, Cultured; Epidermal Growth Factor; Mice; Neoplasms, Experimental; Peptides; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1979 |
Two-stage carcinogenesis with rat embryo cells in tissue culture.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Benzopyrenes; Cell Transformation, Neoplastic; Clone Cells; Croton Oil; Fibroblasts; Neoplasms, Experimental; Phorbol Esters; Phorbols; Rats | 1977 |
Induction of the formation of new hair follicles in mouse tail epidermis by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Female; Hair; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tail; Tetradecanoylphorbol Acetate | 1977 |
Development of a system for controlled release of benzo(a)pyrene, 7,12-dimethylbenz(a)anthracene, and phorbol ester for tumor induction in heterotopic tracheal grafts.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bees; Benz(a)Anthracenes; Benzopyrenes; Carbon; Delayed-Action Preparations; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred F344; Solubility; Tetradecanoylphorbol Acetate; Trachea; Tracheal Neoplasms; Transplantation, Isogeneic; Waxes | 1978 |
Epidermal prostaglandins after topical application of a tumor promotor.
Topics: Administration, Topical; Animals; Male; Mice; Neoplasms, Experimental; Phorbols; Prostaglandins E; Prostaglandins F; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Effect of phorbol ester tumor promoters on the expression of melanogenesis in B-16 melanoma cells.
Topics: Animals; Cell Differentiation; Clone Cells; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1979 |
Systemic promoting action and leukemogenesis in SWR mice by phorbol and structurally related polyfunctional diterpenes.
Topics: Animals; Cocarcinogenesis; Dimethylnitrosamine; Diterpenes; Female; Leukemia, Experimental; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Phorbols; Structure-Activity Relationship | 1979 |
Suppression of natural antitumour defence mechanisms by phorbol esters.
Topics: Animals; Cytotoxicity, Immunologic; Depression, Chemical; Immunity, Innate; Killer Cells, Natural; Macrophages; Mice; Neoplasms, Experimental; Phorbols; Rats; Spleen; Tetradecanoylphorbol Acetate | 1979 |
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis by vitamin A analogs (retinoids).
Topics: Animals; Carboxy-Lyases; Drug Evaluation, Preclinical; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Phorbols; Polyamines; Skin; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Vitamin A | 1978 |
Effect of aging in two-stage carcinogenesis on mouse skin with phorbol myristate acetate as promoting agent.
Topics: Aging; Animals; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Phorbols; Skin Neoplasms; Statistics as Topic; Tetradecanoylphorbol Acetate | 1978 |
Tumor-promoting activity of 2,3-dihydrophorbol myristate acetate and phorbolol myristate acetate in mouse skin.
Topics: Animals; Dermatitis, Contact; Female; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate | 1978 |
Metabolic conversion of 12-O-tetradecanoylphorbol-13-acetate in adult and newborn mouse skin and mouse liver microsomes.
Topics: Animals; Animals, Newborn; Esterases; Female; In Vitro Techniques; Metabolic Clearance Rate; Mice; Mice, Inbred BALB C; Microsomes, Liver; Neoplasms, Experimental; Phorbol Esters; Phorbols; Skin; Tetradecanoylphorbol Acetate | 1978 |
Non-phorbol mouse skin tumor promoters do not mimic phorbol myristate acetate in its effects on chick embryo fibroblasts.
Topics: Acetates; Animals; Anthralin; Cantharidin; Carcinogens; Cell Membrane; Chick Embryo; Cytochalasin B; Deoxyglucose; Fibroblasts; Glycoproteins; Lauric Acids; Neoplasms, Experimental; Oleic Acids; Palmitic Acids; Phenols; Phorbols; Skin Neoplasms; Stearic Acids; Tetradecanoylphorbol Acetate | 1978 |
Two-stage malignant transformation in hamster embryo cells.
Topics: Agar; Animals; Benz(a)Anthracenes; Cell Transformation, Neoplastic; Cricetinae; Methylcholanthrene; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate; Time Factors | 1979 |
Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.
Topics: Animals; Carboxy-Lyases; Enzyme Induction; Female; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; Tretinoin; Vitamin A | 1979 |
Inhibition of two-stage carcinogenesis in mouse skin with bis(2-chloroethyl)sulfide.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Mice; Mice, Inbred ICR; Mustard Compounds; Neoplasms, Experimental; Papilloma; Phorbols; Skin Neoplasms; Sulfides; Tetradecanoylphorbol Acetate | 1976 |
Epidermal cell proliferation and promoting ability of phorbol esters.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Edema; Female; Hyperplasia; Inflammation; Mice; Neoplasms, Experimental; Papilloma; Phorbol Esters; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1976 |
Diaplacental carcinogenesis: initiation with the carcinogens dimethylbenzanthracene (DMBA) and urethane during fetal life and postnatal promotion with the phorbol ester TPA in a modified 2-stage Berenblum/Mottram experiment.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Drug Synergism; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Mice; Neoplasms, Experimental; Phorbols; Pregnancy; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1976 |
Improved tumour yields by means of a TPA-DMBA-TPA variation of the Berenrlum-Mottram experiment on the back skin of NMRI mice. The effect of stationary hyperplasia without inflammation.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Benz(a)Anthracenes; Carcinoma; Female; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Effect of phorbol myristate acetate on the recovery of spontaneous and ultraviolet light-induced 6-thioguanine and ouabain-resistant Chinese hamster cells.
Topics: Animals; Cell Survival; Cells, Cultured; Cricetinae; DNA Repair; Drug Resistance; Mutation; Neoplasms, Experimental; Ouabain; Phorbols; Tetradecanoylphorbol Acetate; Thioguanine; Time Factors; Ultraviolet Rays | 1977 |
Histone phosphorylation and synthesis of DNA and RNA during phases of proliferation and differentiation induced in mouse epidermis by the tumor promoter 12-O-tetradecanoyl-phorbol-13-acetate.
Topics: Animals; Cell Differentiation; Cell Division; DNA; DNA, Neoplasm; Female; Histones; Mice; Neoplasms, Experimental; Phorbols; Phosphorus; RNA; RNA, Neoplasm; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1977 |
Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activator.
Topics: Animals; Anti-Inflammatory Agents; Cell Division; Cells, Cultured; Depression, Chemical; DNA; Female; Fluocinolone Acetonide; Fluocinonide; Mice; Neoplasms, Experimental; Phorbol Esters; Phorbols; Plasminogen Activators; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate | 1977 |
Vitamin A acid (retinoic acid), a potent inhibitor of 12-O-tetradecanoyl-phorbol-13-acetate-induced ornithine decarboxylase activity in mouse epidermis.
Topics: Adenosylmethionine Decarboxylase; Animals; Carboxy-Lyases; Drug Administration Schedule; Enzyme Induction; Female; In Vitro Techniques; Mice; Neoplasms, Experimental; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Tretinoin; Vitamin A | 1977 |
Selective promoting activity of phorbol myristate acetate in experimental skin carcinogenesis.
Topics: Animals; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Male; Methylcholanthrene; Mice; Neoplasms, Experimental; Phorbols; Precancerous Conditions; Rhabdomyosarcoma; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors | 1976 |
Decrease of epidermal histidase activity by tumor-promoting phorbol esters.
Topics: Ammonia-Lyases; Animals; Benz(a)Anthracenes; Carcinogens; Depression, Chemical; Histidine Ammonia-Lyase; Male; Mice; Mice, Nude; Neoplasms, Experimental; Phorbols; Polysorbates; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Urethane | 1975 |
Mechanism of calcium ionophore A23187-induced priming of bone marrow-derived macrophages for tumor cell killing: relationship to priming by interferon.
Topics: Animals; Bone Marrow Cells; Calcimycin; Cytotoxicity, Immunologic; Diglycerides; Dose-Response Relationship, Drug; Interferons; Lipopolysaccharides; Macrophages; Male; Mice; Neoplasms, Experimental; Phorbols; Platelet Activating Factor; Tetradecanoylphorbol Acetate | 1985 |
12-O-tetradecanoyl-phorbol-13-acetate-induced differentiation of human neuroblastoma cells is not accompanied by an increase in the intracellular concentration of cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrier Proteins; Clone Cells; Colchicine; Cyclic AMP; Mice; Neoplasms, Experimental; Neuroblastoma; Phorbols; Protein Binding; Tetradecanoylphorbol Acetate | 1985 |
[The actions of TPA-type as well as non-TPA type tumor promoters and their mechanism(s) in tumor promotion].
Topics: Acrylamides; Animals; Arachidonic Acid; Arachidonic Acids; Carcinogens; Cnidarian Venoms; Enzyme Activation; Humans; Lyngbya Toxins; Mice; Neoplasms, Experimental; Phorbols; Plant Extracts; Protein Kinase C; Receptors, Cell Surface; Skin Neoplasms; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Thapsigargin | 1986 |
Studies on biomodulators of glucocorticoid actions; the nature and the modes of actions of glucocorticoid potency amplifiers.
Topics: Animals; Dexamethasone; Diglycerides; Drug Synergism; Enzyme Induction; Epidermal Growth Factor; Glucocorticoids; Liver; Male; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Phorbols; Rats; Rats, Inbred Strains; Tyrosine Transaminase | 1987 |
Enhancement of selective tumor cell binding by activated murine macrophages in response to phorbol myristate acetate.
Topics: Animals; Cell Adhesion; Cell Line; Cytoskeleton; Hydrogen Peroxide; Kinetics; Macrophage Activation; Macrophages; Mice; Mycobacterium bovis; Neoplasms, Experimental; Phorbols; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Trypsin | 1986 |
[Enhancement of the transforming activity of simian adenovirus S5 and of the DNA from human adenovirus type I by benzo(a)pyrene and TPA].
Topics: Adenoviridae; Adenoviruses, Human; Adenoviruses, Simian; Animals; Animals, Newborn; Benzo(a)pyrene; Cell Line; Cell Transformation, Viral; Cells, Cultured; Chlorocebus aethiops; Cricetinae; DNA, Viral; Humans; Kidney; Mesocricetus; Neoplasms, Experimental; Phorbols; Rats; Tetradecanoylphorbol Acetate; Time Factors | 1986 |
Ionizing radiation as an initiator in the mouse two-stage model of skin tumor formation.
Topics: Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis; Female; Mice; Neoplasms, Experimental; Papilloma; Phorbols; Skin; Skin Neoplasms; Tetradecanoylphorbol Acetate; Time Factors; X-Rays | 1986 |
Correlation of murine susceptibility to tumor, parasite and bacterial challenge with altered cell-mediated immunity following systemic exposure to the tumor promoter phorbol myristate acetate.
Topics: Animals; Cell Line; Cytotoxicity, Immunologic; Female; Immunity, Cellular; Immunity, Innate; Killer Cells, Natural; Listeriosis; Macrophage Activation; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; T-Lymphocytes, Cytotoxic; Tetradecanoylphorbol Acetate; Trichinellosis | 1985 |
[TPA enhancement of the mutagenic and transforming action of bovine adenovirus type 3 on cultured mouse cells].
Topics: Adenoviridae; Animals; Cattle; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Mice; Mice, Inbred C3H; Mutation; Neoplasm Transplantation; Neoplasms, Experimental; Phorbols; Tetradecanoylphorbol Acetate | 1985 |
A strain of hairless mouse susceptible to tumorigenesis by TPA alone: studies with 8-methoxypsoralen and solar simulated radiation.
Topics: Animals; Cocarcinogenesis; Female; Methoxsalen; Mice; Mice, Hairless; Neoplasms, Experimental; Phorbols; PUVA Therapy; Sunlight; Tetradecanoylphorbol Acetate | 1985 |