phorbol-12-13-didecanoate has been researched along with Leukemia--Lymphoid* in 1 studies
1 other study(ies) available for phorbol-12-13-didecanoate and Leukemia--Lymphoid
| Article | Year |
|---|---|
Sialic acid lyase in human promyelocytic leukemic cells (HL-60) during phorbol-ester-induced differentiation.
There is a marked increase in the activity of sialic acid lyase (N-acetylneuraminate lyase; EC 4.1.3.3; also known as sialic acid aldolase) in HL-60 cells induced to differentiate into macrophages by the phorbol ester, tetradecanoylphorbol 12-myristate 13 acetate (TPA). Exposure of HL-60 cells to retinoic acid, butyric acid or dimethyl sulfoxide has little or no effect. The level of the enzyme remains unaltered in HL-60 cells grown in the presence of an inactive analog of TPA, nor does it change in variants of HL-60 cells resistant to TPA. Topics: beta-D-Galactoside alpha 2-6-Sialyltransferase; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Humans; Leukemia, Lymphoid; Oxo-Acid-Lyases; Phorbol Esters; Sialyltransferases; Tetradecanoylphorbol Acetate; Tretinoin | 1986 |