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phorbol 12,13-dibutyrate and Cell Transformation, Neoplastic

phorbol 12,13-dibutyrate has been researched along with Cell Transformation, Neoplastic in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199015 (62.50)18.7374
1990's8 (33.33)18.2507
2000's1 (4.17)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Del Peso, L; Lacal, JC; Lucas, L; Penalva, V; Ramírez de Molina, A1
Arcoleo, J; Backer, J; Gattoni-Celli, S; Hsiao, WL; Jeffrey, A; Kirschmeier, P; Okin, E; Weinstein, IB1
De Larco, JE; Shoyab, M; Todaro, GJ1
Fujiki, H; Kakunaga, T; Mullinix, MG; Shimomura, K; Sugimura, T1
Collins, M; Rozengurt, E1
Jaken, S; Liao, L; Ramsay, K1
Autrup, H; Christensen, B; Kieler, J; Skouv, J1
Chen, ZH; Gopalakrishna, R; Gundimeda, U1
Dunn, JA; Faletto, MB; Gurtoo, HL; Kasper, SJ1
Fabbro, D; Imber, R1
Campisi, J; Park, HY1
Barritt, GJ; Hughes, BP; Polverino, AJ1
Burstein, DE; Lacal, JC; Pellicer, A; Thomson, TM; Trotta, RJ1
Friedman, B; Hicks, K; Rosner, MR1
Mazurek, N; Megidish, T1
Basi, G; Bruni, P; Chiarugi, V; Farnararo, M; Magnelli, L; Pasquali, F; Ruggiero, M1
Blumberg, PM; Nakakuma, H; Willingham, MC1
Bell, RM; Finn, OJ; Persons, DA; Wilkison, WO1
Horiuchi, T; Kusaba, T; Mayumi, T; Nagasawa, K1
Chida, K; Kato, N; Kuroki, T; Yamada, S1
Birchmeier, W; Hamel, E; Katoh, F; Mueller, G; Yamasaki, H1
Aaronson, SA; Blumberg, PM; Fleming, TP; Lacal, JC; Warren, BS1
McCaffrey, PG; Rosner, MR1
Aguelon-Pegouries, AM; Enomoto, T; Furstenberger, G; Marks, F; Martel, N; Yamasaki, H1

Reviews

3 review(s) available for phorbol 12,13-dibutyrate and Cell Transformation, Neoplastic

ArticleYear
Molecular mechanisms of tumor promotion and multistage carcinogenesis.
    Princess Takamatsu symposia, 1983, Volume: 14

    Topics: Adenosine Triphosphate; Animals; Base Sequence; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Transformation, Neoplastic; ErbB Receptors; Humans; Lyngbya Toxins; Molecular Conformation; Neoplasms; Oncogenes; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Protein Kinases; Receptors, Cell Surface; Receptors, Drug; Receptors, Immunologic; Structure-Activity Relationship; Tetradecanoylphorbol Acetate

1983
Epidermal growth factor receptors interact with transforming growth factors produced by certain human tumor cells and are distinct from specific membrane receptors for phorbol and ingenol esters.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cocarcinogenesis; ErbB Receptors; Humans; Neoplasms; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Transforming Growth Factors

1982
Molecular aspects of growth factor action: receptors and intracellular signals.
    The Journal of pathology, 1983, Volume: 141, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Epidermal Growth Factor; Feedback; Growth Substances; Humans; Mice; Mitogens; Phorbol 12,13-Dibutyrate; Phorbol Esters; Rats; Receptors, Drug

1983

Other Studies

21 other study(ies) available for phorbol 12,13-dibutyrate and Cell Transformation, Neoplastic

ArticleYear
Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1.
    International journal of oncology, 2002, Volume: 21, Issue:3

    Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Cells, Cultured; Enzyme Activation; Fibroblasts; Mice; Mutation; Phorbol 12,13-Dibutyrate; Phosphatidylinositol 3-Kinases; Phospholipase D; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-raf; ral Guanine Nucleotide Exchange Factor; ras Proteins; Rats; Transfection

2002
Bromine residue at hydrophilic region influences biological activity of aplysiatoxin, a tumor promoter.
    Science (New York, N.Y.), 1983, Dec-16, Volume: 222, Issue:4629

    Topics: Animals; Caenorhabditis elegans Proteins; Carcinogens; Carrier Proteins; Cell Line; Cell Transformation, Neoplastic; Chemical Phenomena; Chemistry; DNA; Epidermal Growth Factor; ErbB Receptors; Lactones; Lyngbya Toxins; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1983
Protein kinase C isozymes in progressively transformed rat embryo fibroblasts.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:11

    Topics: Animals; Cell Division; Cell Fractionation; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Fibroblasts; Isoenzymes; Kinetics; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-delta; Rats; Simian virus 40; Transfection

1994
Two phorbol ester receptor affinities in partially transformed human urothelial cells and decrease of receptor binding in desensitized cells.
    Experientia, 1993, Jan-15, Volume: 49, Issue:1

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line, Transformed; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Tetradecanoylphorbol Acetate; Urinary Bladder; Urinary Bladder Neoplasms

1993
Selenocompounds induce a redox modulation of protein kinase C in the cell, compartmentally independent from cytosolic glutathione: its role in inhibition of tumor promotion.
    Archives of biochemistry and biophysics, 1997, Dec-01, Volume: 348, Issue:1

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Chromatography, DEAE-Cellulose; Cystine; Cytosol; Glutathione; Glutathione Disulfide; Isoenzymes; Kinetics; Mice; Organoselenium Compounds; Oxidation-Reduction; Phorbol 12,13-Dibutyrate; Protein Kinase C; Sodium Selenite; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1997
Aflatoxin-transformed C3H/10T1/2 cells overexpress protein kinase C and have an altered response to phorbol ester treatments.
    Cancer research, 1992, Feb-15, Volume: 52, Issue:4

    Topics: Aflatoxin B1; Animals; Arachidonic Acid; Blotting, Western; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Division; Cell Line; Cell Transformation, Neoplastic; Isoenzymes; Kinetics; Mice; Mice, Inbred C3H; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug

1992
Tumor-promoting phorbol ester and activated Ha-ras synergistically reduce the interleukin 3 requirement in a mast cell line.
    Cancer research, 1991, Jan-15, Volume: 51, Issue:2

    Topics: Animals; Blotting, Northern; Cell Division; Cell Line; Cell Transformation, Neoplastic; Genes, ras; Genetic Vectors; Interleukin-3; Mast Cells; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Restriction Mapping; Tetradecanoylphorbol Acetate; Transfection

1991
Posttranslational control of cyclic AMP-dependent protein kinase by phorbol ester in normal but not in chemically transformed 3T3 cells.
    Cancer research, 1990, Nov-15, Volume: 50, Issue:22

    Topics: Animals; Blotting, Western; Cell Line; Cell Transformation, Neoplastic; Cyclic AMP; Dose-Response Relationship, Drug; Down-Regulation; Gene Expression; Mice; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinases; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-myc; Receptors, Cyclic AMP; RNA, Messenger; Time Factors

1990
NIH-3T3 cells transformed with a ras oncogene exhibit a protein kinase C-mediated inhibition of agonist-stimulated Ca2+ inflow.
    The Biochemical journal, 1990, Oct-15, Volume: 271, Issue:2

    Topics: Animals; Bombesin; Calcium; Cell Line, Transformed; Cell Transformation, Neoplastic; Egtazic Acid; Enzyme Activation; Fibroblasts; Gastrin-Releasing Peptide; Genes, ras; Mice; Peptides; Phorbol 12,13-Dibutyrate; Platelet-Derived Growth Factor; Protein Kinase C; Receptors, Bombesin; Receptors, Neurotransmitter

1990
Potentiation of oncogenic N-ras-induced neurite outgrowth and ornithine decarboxylase activity by phorbol dibutyrate and protein kinase inhibitor H-8.
    Journal of cellular physiology, 1990, Volume: 143, Issue:1

    Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; Colforsin; Dexamethasone; Epidermal Growth Factor; Isoquinolines; Nerve Growth Factors; Neurons; Oncogene Protein p21(ras); Ornithine Decarboxylase; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Kinase Inhibitors; Rats; Tetradecanoylphorbol Acetate; Tretinoin; Tumor Cells, Cultured

1990
Basic fibroblast-like growth factor is present in the conditioned medium of simian sarcoma virus transformed NRK cells.
    Biochemical and biophysical research communications, 1989, Nov-15, Volume: 164, Issue:3

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; DNA Replication; Epidermal Growth Factor; ErbB Receptors; Fibroblast Growth Factors; Kidney; Kinetics; Mice; Phorbol 12,13-Dibutyrate; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogenes; Rats; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Retroviruses, Simian; Sarcoma Virus, Woolly Monkey

1989
A mutant protein kinase C that can transform fibroblasts.
    Nature, 1989, Dec-14, Volume: 342, Issue:6251

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Compartmentation; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Cloning, Molecular; Fibrosarcoma; Mice; Molecular Sequence Data; Neoplasms, Experimental; Phorbol 12,13-Dibutyrate; Protein Kinase C

1989
Synthesis of diacylglycerol de novo is responsible for permanent activation and down-regulation of protein kinase C in transformed cells.
    Biochemical and biophysical research communications, 1989, Oct-31, Volume: 164, Issue:2

    Topics: Animals; Caenorhabditis elegans Proteins; Carbon Radioisotopes; Carrier Proteins; Cell Transformation, Neoplastic; Cells, Cultured; Cytosol; Deoxyglucose; Diglycerides; Genes, ras; Glucose; Glycerides; Glycolysis; Kinetics; Mice; Mice, Inbred Strains; Oncogenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug

1989
Effect of microinjected catalytic fragment of protein kinase C on morphological change in Swiss 3T3 cells.
    Cancer communications, 1989, Volume: 1, Issue:2

    Topics: Animals; Brain; Cell Transformation, Neoplastic; Cells, Cultured; Fluorescent Antibody Technique; Mice; Microinjections; Phorbol 12,13-Dibutyrate; Protein Kinase C

1989
Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA.
    Cell, 1988, Feb-12, Volume: 52, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytosol; DNA; Fibroblasts; Isoenzymes; Mice; Mice, Nude; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Rats; RNA, Messenger

1988
Phorbol ester receptors and the induction of differentiation in the human T lymphoblastic cell line MOLT-3.
    Experimental cell biology, 1988, Volume: 56, Issue:1-2

    Topics: Caenorhabditis elegans Proteins; Carrier Proteins; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Resistance; Humans; Leukemia-Lymphoma, Adult T-Cell; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Drug; Statistics as Topic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1988
Protein kinase C activities and bindings of a phorbol ester tumor promoter in 41 cell lines.
    Biochemical and biophysical research communications, 1988, Nov-30, Volume: 157, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Humans; Mice; Oncogenes; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats

1988
Transforming growth factor beta as a potent promoter in two-stage BALB/c 3T3 cell transformation.
    Cancer research, 1988, May-15, Volume: 48, Issue:10

    Topics: Animals; Cell Communication; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Epidermal Growth Factor; Methylcholanthrene; Mice; Peptides; Phorbol 12,13-Dibutyrate; Phorbol Esters; Transforming Growth Factors

1988
Involvement of functional protein kinase C in the mitogenic response to the H-ras oncogene product.
    Molecular and cellular biology, 1987, Volume: 7, Issue:11

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA Replication; Genes, ras; Mice; Mice, Inbred Strains; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras)

1987
Growth state-dependent regulation of protein kinase C in normal and transformed murine cells.
    Cancer research, 1987, Feb-15, Volume: 47, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Epidermal Growth Factor; Fibroblasts; Mice; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C

1987
Comparative effects of a complete tumor promoter, TPA, and a second-stage tumor promoter, RPA, on intercellular communication, cell differentiation and cell transformation.
    Carcinogenesis, 1985, Volume: 6, Issue:8

    Topics: Animals; Cell Communication; Cell Differentiation; Cell Transformation, Neoplastic; Cells, Cultured; Mice; Mice, Inbred BALB C; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate

1985