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phorbol 12,13-dibutyrate and Breast Neoplasms

phorbol 12,13-dibutyrate has been researched along with Breast Neoplasms in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19905 (27.78)18.7374
1990's6 (33.33)18.2507
2000's7 (38.89)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acs, P; Ahmad, S; Blumberg, PM; Bogi, K; Glazer, RI; Kozikowski, AP; Lewin, NE; Ma, D; Modarres, S; Wang, S; Yao, J1
Ramakrishnan, R; Rathinavelu, A; Zell, JA1
Kruger, JS; Reddy, KB1
Krebs, CE; Liu, DS; Liu, SJ1
Brooks, C; Bulun, SE; Chen, D; Innes, J; Li, N; Lin, Z; Lu, M; Reierstad, S1
Collins, M; McKay, I; Rozengurt, E; Taylor-Papadimitriou, J1
Budworth, J; Gescher, A1
Fine, RL; Harrison, SD; Sachs, CW; Safa, AR1
Chen, ZH; Gopalakrishna, R; Gundimeda, U1
deFazio, A; Lee, CS; Ormandy, CJ; Sutherland, RL1
Basu, A1
Malavé, A; Ramakrishnan, R; Rathinavelu, A; Zell, JA1
Epstein, RJ; Gulliford, T; Huang, G; Ouyang, X; Smith, G; Zhang, H1
Arpin, M; Bastiaens, PI; Gautreau, A; Gschmeissner, S; Hughes, WE; Monypenny, J; Ng, T; Parker, PJ; Parsons, M; Verveer, PJ; Zicha, D1
Chabner, BA; Fine, RL; Patel, J1
Bayard, F; Darbon, JM; Valette, A1
Arnold, AJ; Simpson, RU1
Costa, SD; Eppenberger, U; Fabbro, D; Küng, W; Regazzi, R1

Other Studies

18 other study(ies) available for phorbol 12,13-dibutyrate and Breast Neoplasms

ArticleYear
Modeling, chemistry, and biology of the benzolactam analogues of indolactam V (ILV). 2. Identification of the binding site of the benzolactams in the CRD2 activator-binding domain of PKCdelta and discovery of an ILV analogue of improved isozyme selectivit
    Journal of medicinal chemistry, 1997, Apr-25, Volume: 40, Issue:9

    Topics: Antineoplastic Agents; Binding Sites; Binding, Competitive; Breast Neoplasms; Cell Division; Crystallography, X-Ray; Enzyme Inhibitors; Female; Humans; Hydrogen Bonding; Indoles; Isoenzymes; Lactams; Lyngbya Toxins; Models, Molecular; Molecular Conformation; Molecular Structure; Mutagenesis, Site-Directed; Protein Kinase C; Tumor Cells, Cultured

1997
Regulation of mdm2 mRNA expression in human breast tumor-derived GI-101A cells.
    Life sciences, 2002, Oct-04, Volume: 71, Issue:20

    Topics: Alkaloids; Animals; Base Sequence; Benzophenanthridines; Breast Neoplasms; Diethylstilbestrol; DNA Primers; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinases; Nuclear Proteins; PC12 Cells; Phenanthridines; Phorbol 12,13-Dibutyrate; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen; Tumor Cells, Cultured

2002
Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells.
    Molecular cancer research : MCR, 2003, Volume: 1, Issue:11

    Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; ErbB Receptors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Serine-Threonine Kinases; rho-Associated Kinases; Transforming Growth Factor alpha; Tyrosine

2003
Proliferation of human breast cancer cells and anti-cancer action of doxorubicin and vinblastine are independent of PKC-alpha.
    Journal of cellular biochemistry, 2007, May-15, Volume: 101, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Cell Shape; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Female; Humans; Phorbol 12,13-Dibutyrate; Protein Kinase C-alpha; Staurosporine; Vinblastine

2007
Prostaglandin E(2) induces breast cancer related aromatase promoters via activation of p38 and c-Jun NH(2)-terminal kinase in adipose fibroblasts.
    Cancer research, 2007, Sep-15, Volume: 67, Issue:18

    Topics: Activating Transcription Factor 2; Adipose Tissue; Aromatase; Breast Neoplasms; Cyclic CMP; Dinoprostone; Enzyme Activation; Fibroblasts; Humans; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phorbol 12,13-Dibutyrate; Phosphorylation; Promoter Regions, Genetic; RNA, Messenger; RNA, Small Interfering

2007
An inhibitory effect of tumour promoters on human epithelial cell growth can be dissociated from an effect on junctional communication.
    Experimental cell research, 1983, Volume: 145, Issue:2

    Topics: Breast Neoplasms; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Communication; Cell Division; Cell Line; Cell Transformation, Viral; Epidermal Cells; Epidermis; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Receptors, Cell Surface; Receptors, Drug; Tetradecanoylphorbol Acetate

1983
Differential inhibition of cytosolic and membrane-derived protein kinase C activity by staurosporine and other kinase inhibitors.
    FEBS letters, 1995, Apr-03, Volume: 362, Issue:2

    Topics: Alkaloids; Breast Neoplasms; Cell Membrane; Cytosol; Humans; Immunoblotting; Indoles; Naphthalenes; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Protein Kinase C; Staurosporine; Tumor Cells, Cultured

1995
Partial inhibition of multidrug resistance by safingol is independent of modulation of P-glycoprotein substrate activities and correlated with inhibition of protein kinase C.
    The Journal of biological chemistry, 1995, Nov-03, Volume: 270, Issue:44

    Topics: Affinity Labels; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Breast Neoplasms; Cell Line; Cell Membrane; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Enzyme Inhibitors; Female; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Recombinant Proteins; Sphingosine; Substrate Specificity; Tumor Cells, Cultured; Verapamil; Vinblastine

1995
Tamoxifen modulates protein kinase C via oxidative stress in estrogen receptor-negative breast cancer cells.
    The Journal of biological chemistry, 1996, Jun-07, Volume: 271, Issue:23

    Topics: Animals; Antioxidants; Breast Neoplasms; Cattle; Cell Division; Cell Membrane; Enzyme Inhibitors; Estrogen Antagonists; Female; Humans; In Vitro Techniques; Oxidative Stress; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rabbits; Receptors, Estrogen; Second Messenger Systems; Tamoxifen; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vitamin E

1996
Inverse regulation of oestrogen receptor and epidermal growth factor receptor gene expression in MCF-7 breast cancer cells treated with phorbol ester.
    The Journal of steroid biochemistry and molecular biology, 1996, Volume: 58, Issue:3

    Topics: Breast Neoplasms; Carcinogens; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Phorbol 12,13-Dibutyrate; Receptors, Estrogen; RNA, Messenger; Tumor Cells, Cultured

1996
The involvement of novel protein kinase C isozymes in influencing sensitivity of breast cancer MCF-7 cells to tumor necrosis factor-alpha.
    Molecular pharmacology, 1998, Volume: 53, Issue:1

    Topics: Antineoplastic Agents; Breast Neoplasms; Bryostatins; Carcinogens; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Lactams; Lactones; Macrolides; Maleimides; Phorbol 12,13-Dibutyrate; Protein Kinase C; Receptors, Tumor Necrosis Factor; Sensitivity and Specificity; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1998
Expression of vascular endothelial growth factor mRNA in GI-101A and HL-60 cell lines.
    Biochemical and biophysical research communications, 2000, Apr-21, Volume: 270, Issue:3

    Topics: Alkaloids; Alternative Splicing; Antineoplastic Agents; Benzophenanthridines; Breast Neoplasms; Diethylstilbestrol; Endothelial Growth Factors; Female; Gene Expression Regulation, Neoplastic; Genetic Variation; HL-60 Cells; Humans; Lymphokines; Phenanthridines; Phorbol 12,13-Dibutyrate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tamoxifen; Transcription, Genetic; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
Association of ErbB2 Ser1113 phosphorylation with epidermal growth factor receptor co-expression and poor prognosis in human breast cancer.
    Molecular and cellular biochemistry, 2001, Volume: 218, Issue:1-2

    Topics: Animals; Antibodies, Monoclonal; Becaplermin; Breast Neoplasms; Cells, Cultured; Colforsin; Epidermal Growth Factor; ErbB Receptors; Fluorescent Antibody Technique; Humans; Immunoblotting; Mice; Microscopy, Confocal; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphoserine; Platelet-Derived Growth Factor; Prognosis; Proto-Oncogene Proteins c-sis; Receptor, ErbB-2; Transfection; Vanadates

2001
Ezrin is a downstream effector of trafficking PKC-integrin complexes involved in the control of cell motility.
    The EMBO journal, 2001, Jun-01, Volume: 20, Issue:11

    Topics: Amino Acid Substitution; Breast Neoplasms; Cell Membrane; Cell Movement; Chromones; Cytoskeletal Proteins; Enzyme Inhibitors; Female; Green Fluorescent Proteins; Humans; Integrin beta1; Isoenzymes; Kinetics; Luminescent Proteins; Microscopy, Confocal; Morpholines; Mutagenesis, Site-Directed; Phorbol 12,13-Dibutyrate; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphothreonine; Protein Kinase C; Protein Kinase C-alpha; Recombinant Fusion Proteins; Tumor Cells, Cultured; Wound Healing

2001
Phorbol esters induce multidrug resistance in human breast cancer cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1988, Volume: 85, Issue:2

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinogens; Cell Line; Clone Cells; Drug Resistance; Female; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phosphorylation; Protein Kinase C

1988
Phorbol esters inhibit the proliferation of MCF-7 cells. Possible implication of protein kinase C.
    Biochemical pharmacology, 1986, Aug-15, Volume: 35, Issue:16

    Topics: Breast Neoplasms; Cell Division; Cell Line; Dose-Response Relationship, Drug; Female; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters; Phorbols; Protein Kinase C; Tetradecanoylphorbol Acetate

1986
Calcium antagonizes 1,25-dihydroxyvitamin D3 inhibition of breast cancer cell proliferation.
    Endocrinology, 1986, Volume: 119, Issue:5

    Topics: Breast Neoplasms; Calcitriol; Calcium; Cell Division; Cell Line; DNA Replication; Dose-Response Relationship, Drug; Humans; Phorbol 12,13-Dibutyrate; Phorbol Esters

1986
The cytosolic phorboid receptor correlates with hormone dependency in six mammary carcinoma cell lines.
    Biochemical and biophysical research communications, 1985, Dec-17, Volume: 133, Issue:2

    Topics: Breast Neoplasms; Caenorhabditis elegans Proteins; Carrier Proteins; Cell Line; Cytosol; Electrophoresis, Polyacrylamide Gel; Humans; Neoplasms, Hormone-Dependent; Phorbol 12,13-Dibutyrate; Phorbol Esters; Protein Kinase C; Receptors, Drug; Receptors, Immunologic; Subcellular Fractions

1985