phloroglucinol has been researched along with Neoplasms in 14 studies
Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In recent, targeting mitochondria in cancer is considered to be a challenging task." | 1.51 | Phloroglucinol-conjugated gold nanoparticles targeting mitochondrial membrane potential of human cervical (HeLa) cancer cell lines. ( Kumar, P; Mahalakshmi, M, 2019) |
| "We used epithelial cancer cells to study the effects of MC-A and TQ on EMT." | 1.43 | Novel anti-cancer agent myrtucommulone-A and thymoquinone abrogate epithelial-mesenchymal transition in cancer cells mainly through the inhibition of PI3K/AKT signalling axis. ( Canatan, H; Iskender, B; Izgi, K, 2016) |
| "JQ-101 suppressed cancer cell growth and survival by targeting SIRT1, and also exhibited selective cytotoxicity towards a panel of human tumor cell lines, while producing no toxicity in two normal human cell types at comparable concentrations." | 1.40 | Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities. ( Chiao, CY; Dai, Y; Faller, DV; Porco, JA; Qi, J; Zhang, Q; Zhu, L, 2014) |
| "National Cancer Institute's Open Repository." | 1.38 | Glycolysis inhibitor screening identifies the bis-geranylacylphloroglucinol protonophore moronone from Moronobea coccinea. ( Datta, S; Jekabsons, MB; Li, J; Mahdi, F; Nagle, DG; Zhou, YD, 2012) |
| "The compounds were examined for their cancer chemopreventive potential, in comparison with the monomer phloroglucinol." | 1.36 | In vitro chemopreventive potential of fucophlorethols from the brown alga Fucus vesiculosus L. by anti-oxidant activity and inhibition of selected cytochrome P450 enzymes. ( Carmeli, S; Gerhäuser, C; Glombitza, KW; Kehraus, S; Klimo, K; König, GM; Krick, A; Parys, S, 2010) |
| "Hyperforin has also been reported to have anti-inflammatory properties." | 1.35 | Mechanisms of Hyperforin as an anti-angiogenic angioprevention agent. ( Albini, A; Garbisa, S; Generoso, L; Lorusso, G; Noonan, DM; Sogno, I; Vannini, N, 2009) |
| "Hyperforin is a plant derived antibiotic from St." | 1.31 | Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis. ( Borner, C; Gilb, B; Kaufmann, T; Kersten, A; Kirkin, V; Kiss, J; Schempp, CM; Simon, JC; Simon-Haarhaus, B; Sleeman, JP; Termeer, CC, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Monteiro, P | 1 |
| Lomartire, S | 1 |
| Cotas, J | 1 |
| Marques, JC | 1 |
| Pereira, L | 1 |
| Gonçalves, AMM | 1 |
| Mahalakshmi, M | 1 |
| Kumar, P | 1 |
| Modak, A | 1 |
| Barui, AK | 1 |
| Patra, CR | 1 |
| Bhaumik, A | 1 |
| Zhu, L | 1 |
| Qi, J | 1 |
| Chiao, CY | 1 |
| Zhang, Q | 1 |
| Porco, JA | 1 |
| Faller, DV | 1 |
| Dai, Y | 1 |
| Cavieres, VA | 1 |
| González, A | 1 |
| Muñoz, VC | 1 |
| Yefi, CP | 1 |
| Bustamante, HA | 1 |
| Barraza, RR | 1 |
| Tapia-Rojas, C | 1 |
| Otth, C | 1 |
| Barrera, MJ | 1 |
| González, C | 1 |
| Mardones, GA | 1 |
| Inestrosa, NC | 1 |
| Burgos, PV | 1 |
| Iskender, B | 1 |
| Izgi, K | 1 |
| Canatan, H | 1 |
| Yang, WS | 1 |
| Stockwell, BR | 1 |
| Lorusso, G | 1 |
| Vannini, N | 1 |
| Sogno, I | 1 |
| Generoso, L | 1 |
| Garbisa, S | 2 |
| Noonan, DM | 1 |
| Albini, A | 1 |
| Parys, S | 1 |
| Kehraus, S | 1 |
| Krick, A | 1 |
| Glombitza, KW | 1 |
| Carmeli, S | 1 |
| Klimo, K | 1 |
| Gerhäuser, C | 1 |
| König, GM | 1 |
| Cheong, JK | 1 |
| Nguyen, TH | 1 |
| Wang, H | 1 |
| Tan, P | 1 |
| Voorhoeve, PM | 1 |
| Lee, SH | 1 |
| Virshup, DM | 1 |
| Datta, S | 1 |
| Li, J | 1 |
| Mahdi, F | 1 |
| Jekabsons, MB | 1 |
| Nagle, DG | 1 |
| Zhou, YD | 1 |
| Donà, M | 1 |
| Dell'Aica, I | 1 |
| Pezzato, E | 1 |
| Sartor, L | 1 |
| Calabrese, F | 1 |
| Della Barbera, M | 1 |
| Donella-Deana, A | 1 |
| Appendino, G | 1 |
| Borsarini, A | 1 |
| Caniato, R | 1 |
| Quiney, C | 1 |
| Billard, C | 1 |
| Salanoubat, C | 1 |
| Fourneron, JD | 1 |
| Kolb, JP | 1 |
| Schempp, CM | 1 |
| Kirkin, V | 1 |
| Simon-Haarhaus, B | 1 |
| Kersten, A | 1 |
| Kiss, J | 1 |
| Termeer, CC | 1 |
| Gilb, B | 1 |
| Kaufmann, T | 1 |
| Borner, C | 1 |
| Sleeman, JP | 1 |
| Simon, JC | 1 |
2 reviews available for phloroglucinol and Neoplasms
| Article | Year |
|---|---|
Call the Eckols: Present and Future Potential Cancer Therapies.
Topics: Antioxidants; Humans; Neoplasms; Phaeophyceae; Phenols; Phloroglucinol; Seaweed; Tannins | 2022 |
Hyperforin, a new lead compound against the progression of cancer and leukemia?
Topics: Anti-Infective Agents; Antidepressive Agents; Antineoplastic Agents; Bridged Bicyclo Compounds; Huma | 2006 |
12 other studies available for phloroglucinol and Neoplasms
| Article | Year |
|---|---|
Phloroglucinol-conjugated gold nanoparticles targeting mitochondrial membrane potential of human cervical (HeLa) cancer cell lines.
Topics: Antineoplastic Agents; Apoptosis; Gold; HeLa Cells; Humans; Membrane Potential, Mitochondrial; Metal | 2019 |
A luminescent nanoporous hybrid material based drug delivery system showing excellent theranostics potential for cancer.
Topics: Antibiotics, Antineoplastic; Cell Line; Cell Proliferation; Doxorubicin; Drug Carriers; Fluorescent | 2013 |
Identification of a novel polyprenylated acylphloroglucinol‑derived SIRT1 inhibitor with cancer‑specific anti-proliferative and invasion-suppressing activities.
Topics: Apoptosis; Cell Movement; Cell Proliferation; Cellular Senescence; Gene Expression Regulation, Neopl | 2014 |
Tetrahydrohyperforin Inhibits the Proteolytic Processing of Amyloid Precursor Protein and Enhances Its Degradation by Atg5-Dependent Autophagy.
Topics: Amyloid beta-Protein Precursor; Animals; Autophagy; Autophagy-Related Protein 5; Blotting, Western; | 2015 |
Novel anti-cancer agent myrtucommulone-A and thymoquinone abrogate epithelial-mesenchymal transition in cancer cells mainly through the inhibition of PI3K/AKT signalling axis.
Topics: Benzoquinones; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Female; Humans; Male; Neoplasms; | 2016 |
Inhibition of casein kinase 1-epsilon induces cancer-cell-selective, PERIOD2-dependent growth arrest.
Topics: Casein Kinase 1 epsilon; Cell Line, Tumor; Cell Survival; Humans; Indoles; Neoplasms; Nuclear Protei | 2008 |
Mechanisms of Hyperforin as an anti-angiogenic angioprevention agent.
Topics: Analysis of Variance; Angiogenesis Inhibitors; Animals; Apoptosis; Bridged Bicyclo Compounds; Cell L | 2009 |
In vitro chemopreventive potential of fucophlorethols from the brown alga Fucus vesiculosus L. by anti-oxidant activity and inhibition of selected cytochrome P450 enzymes.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Aromatase Inhibitors; Biphenyl Compounds; | 2010 |
IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; beta Catenin; Casein Kinase 1 epsilon; Casein Kinas | 2011 |
Glycolysis inhibitor screening identifies the bis-geranylacylphloroglucinol protonophore moronone from Moronobea coccinea.
Topics: Cell Survival; Clusiaceae; Female; Glucose; Glycolysis; Humans; Molecular Structure; Neoplasms; Phlo | 2012 |
Hyperforin inhibits cancer invasion and metastasis.
Topics: Adenocarcinoma; Animals; Apoptosis; Bridged Bicyclo Compounds; Cell Division; Cell Survival; Colonic | 2004 |
Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Bridged Bicyclo Compounds; Caspases; Cell Division; Cytoc | 2002 |