phloroglucinol has been researched along with Multiple Sclerosis in 2 studies
Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cuprizone-induced model was used in this study to mimic the pathological progress of MS." | 5.56 | Phloroglucinol derivative compound 21 attenuates cuprizone-induced multiple sclerosis mice through promoting remyelination and inhibiting neuroinflammation. ( Bao, XQ; Liu, H; Zhang, D; Zhang, Z; Zhao, Z, 2020) |
| "The cuprizone-induced model was used in this study to mimic the pathological progress of MS." | 1.56 | Phloroglucinol derivative compound 21 attenuates cuprizone-induced multiple sclerosis mice through promoting remyelination and inhibiting neuroinflammation. ( Bao, XQ; Liu, H; Zhang, D; Zhang, Z; Zhao, Z, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Z | 1 |
| Bao, XQ | 1 |
| Zhang, Z | 1 |
| Liu, H | 1 |
| Zhang, D | 1 |
| Nosratabadi, R | 1 |
| Rastin, M | 1 |
| Sankian, M | 1 |
| Haghmorad, D | 1 |
| Tabasi, N | 1 |
| Zamani, S | 1 |
| Aghaee, A | 1 |
| Salehipour, Z | 1 |
| Mahmoudi, M | 1 |
2 other studies available for phloroglucinol and Multiple Sclerosis
| Article | Year |
|---|---|
Phloroglucinol derivative compound 21 attenuates cuprizone-induced multiple sclerosis mice through promoting remyelination and inhibiting neuroinflammation.
Topics: Animals; Astrocytes; Brain; Cuprizone; Cytokines; Disease Models, Animal; Drug Discovery; Inflammati | 2020 |
St. John's wort and its component hyperforin alleviate experimental autoimmune encephalomyelitis through expansion of regulatory T-cells.
Topics: Animals; Cell Proliferation; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Fe | 2016 |