phloroglucinol has been researched along with Leukemia in 4 studies
Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The microbial polyketide, 2, 4-diacetylphloroglucinol (DAPG), exhibited a broad-spectrum of anti-leukemic, anti-lung, and anti-breast cancer properties." | 7.83 | Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction with the metastatic proteins than the antiapoptotic Bcl-2 proteins. ( Kennedy, K; Krishna, R; Lakshmi, P; Sakthivel, N; Veena, VK, 2016) |
| "The microbial polyketide, 2, 4-diacetylphloroglucinol (DAPG), exhibited a broad-spectrum of anti-leukemic, anti-lung, and anti-breast cancer properties." | 3.83 | Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction with the metastatic proteins than the antiapoptotic Bcl-2 proteins. ( Kennedy, K; Krishna, R; Lakshmi, P; Sakthivel, N; Veena, VK, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wiechmann, K | 1 |
| Müller, H | 1 |
| Fischer, D | 1 |
| Jauch, J | 1 |
| Werz, O | 1 |
| Veena, VK | 1 |
| Kennedy, K | 1 |
| Lakshmi, P | 1 |
| Krishna, R | 1 |
| Sakthivel, N | 1 |
| Momekov, G | 1 |
| Ferdinandov, D | 1 |
| Zheleva-Dimitrova, D | 1 |
| Nedialkov, P | 1 |
| Girreser, U | 1 |
| Kitanov, G | 1 |
| Weber, CC | 1 |
| Kressmann, S | 1 |
| Fricker, G | 1 |
| Müller, WE | 1 |
4 other studies available for phloroglucinol and Leukemia
| Article | Year |
|---|---|
The acylphloroglucinols hyperforin and myrtucommulone A cause mitochondrial dysfunctions in leukemic cells by direct interference with mitochondria.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Apoptosis; HL-60 Cells; Humans; Leukemia; Mem | 2015 |
Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction with the metastatic proteins than the antiapoptotic Bcl-2 proteins.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Humans; Leukemia; Lung Neoplasms; Molecul | 2016 |
Cytotoxic effects of hyperatomarin, a prenylated phloroglucinol from Hypericum annulatum Moris subsp. annulatum, in a panel of malignant cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; DNA Fragmentation; Dose-Response Rel | 2008 |
Modulation of P-glycoprotein function by St John's wort extract and its major constituents.
Topics: Adenosine Triphosphate; Amitriptyline; Animals; Antidepressive Agents; ATP Binding Cassette Transpor | 2004 |