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phloroglucinol and Breast Cancer

phloroglucinol has been researched along with Breast Cancer in 9 studies

Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.

Research Excerpts

ExcerptRelevanceReference
"The microbial polyketide, 2, 4-diacetylphloroglucinol (DAPG), exhibited a broad-spectrum of anti-leukemic, anti-lung, and anti-breast cancer properties."7.83Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction with the metastatic proteins than the antiapoptotic Bcl-2 proteins. ( Kennedy, K; Krishna, R; Lakshmi, P; Sakthivel, N; Veena, VK, 2016)
"Treatment with phloroglucinol effectively inhibited mesenchymal phenotypes of basal type breast cancer cells through downregulation of SLUG without causing a cytotoxic effect."5.42Phloroglucinol suppresses metastatic ability of breast cancer cells by inhibition of epithelial-mesenchymal cell transition. ( Cui, YH; Hwang, E; Kang, JS; Kim, HJ; Kim, MJ; Kim, RK; Lee, SJ; Lee, YY; Suh, Y; Yoo, KC, 2015)
"Poor prognosis of breast cancer patients is closely associated with metastasis and relapse."5.42Novel anticancer activity of phloroglucinol against breast cancer stem-like cells. ( Hyun, JW; Kim, C; Kim, RK; Lee, SJ; Suh, Y; Uddin, N, 2015)
"The microbial polyketide, 2, 4-diacetylphloroglucinol (DAPG), exhibited a broad-spectrum of anti-leukemic, anti-lung, and anti-breast cancer properties."3.83Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction with the metastatic proteins than the antiapoptotic Bcl-2 proteins. ( Kennedy, K; Krishna, R; Lakshmi, P; Sakthivel, N; Veena, VK, 2016)
" cava)-derived dieckol on movement behavior and the expression of migration-related genes in MCF-7 human breast cancer cell."3.81First evidence that Ecklonia cava-derived dieckol attenuates MCF-7 human breast carcinoma cell migration. ( Choi, EJ; Hwang, JW; Jeon, YJ; Kim, EK; Kim, YS; Lee, JH; Lee, SH; Park, PJ; Tang, Y, 2015)
"Treatment with phloroglucinol effectively inhibited mesenchymal phenotypes of basal type breast cancer cells through downregulation of SLUG without causing a cytotoxic effect."1.42Phloroglucinol suppresses metastatic ability of breast cancer cells by inhibition of epithelial-mesenchymal cell transition. ( Cui, YH; Hwang, E; Kang, JS; Kim, HJ; Kim, MJ; Kim, RK; Lee, SJ; Lee, YY; Suh, Y; Yoo, KC, 2015)
"Poor prognosis of breast cancer patients is closely associated with metastasis and relapse."1.42Novel anticancer activity of phloroglucinol against breast cancer stem-like cells. ( Hyun, JW; Kim, C; Kim, RK; Lee, SJ; Suh, Y; Uddin, N, 2015)
"To uncover genetic dependencies in breast cancer cells that harbor active beta-catenin signaling, we performed RNAi-based loss-of-function screens in breast cancer cell lines in which we had characterized beta-catenin activity."1.36CK1epsilon is required for breast cancers dependent on beta-catenin activity. ( Boehm, JS; Dunn, IF; Firestein, R; Gupta, P; Hahn, WC; Kim, SY; Lander, ES; Ramaswamy, S; Repich, K; Root, DE; Schinzel, AC; Silver, SJ; Wardwell, L; Wittner, B, 2010)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lv, L1
Liu, Y1
Li, L1
Qin, FL1
Li, CJ1
Zhou, YQ1
Zhou, YN1
Wang, H1
Jiao, Y1
Zhao, L1
Kim, RK2
Suh, Y2
Yoo, KC1
Cui, YH1
Hwang, E1
Kim, HJ1
Kang, JS1
Kim, MJ1
Lee, YY1
Lee, SJ2
Kim, EK1
Tang, Y1
Kim, YS1
Hwang, JW1
Choi, EJ1
Lee, JH1
Lee, SH1
Jeon, YJ1
Park, PJ1
Uddin, N1
Hyun, JW1
Kim, C1
Veena, VK1
Kennedy, K1
Lakshmi, P1
Krishna, R1
Sakthivel, N1
Kong, CS1
Kim, JA1
Yoon, NY1
Kim, SK1
Kim, SY1
Dunn, IF1
Firestein, R1
Gupta, P1
Wardwell, L1
Repich, K1
Schinzel, AC1
Wittner, B1
Silver, SJ1
Root, DE1
Boehm, JS1
Ramaswamy, S1
Lander, ES1
Hahn, WC1
Zhang, Y1
Luo, M1
Zu, Y1
Fu, Y1
Gu, C1
Wang, W1
Yao, L1
Efferth, T1
Garzia, L1
D'Angelo, A1
Amoresano, A1
Knauer, SK1
Cirulli, C1
Campanella, C1
Stauber, RH1
Steegborn, C1
Iolascon, A1
Zollo, M1

Other Studies

9 other studies available for phloroglucinol and Breast Cancer

ArticleYear
Pharmacokinetics and tissue distribution of Ebracteolatain A, a potential anti-cancer compound, as determined by an optimized ultra-performance liquid chromatography tandem mass spectrometry method.
    Journal of pharmaceutical and biomedical analysis, 2019, May-30, Volume: 169

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Chr

2019
Phloroglucinol suppresses metastatic ability of breast cancer cells by inhibition of epithelial-mesenchymal cell transition.
    Cancer science, 2015, Volume: 106, Issue:1

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Movement; Epithelial-Mesenchymal Transition;

2015
First evidence that Ecklonia cava-derived dieckol attenuates MCF-7 human breast carcinoma cell migration.
    Marine drugs, 2015, Mar-30, Volume: 13, Issue:4

    Topics: Antineoplastic Agents; Benzofurans; Breast Neoplasms; Cell Movement; Cell Survival; Dioxanes; Dioxin

2015
Novel anticancer activity of phloroglucinol against breast cancer stem-like cells.
    Toxicology and applied pharmacology, 2015, Aug-01, Volume: 286, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Death; Female; Humans; MCF-7 Cells; Mice; Mic

2015
Anti-leukemic, anti-lung, and anti-breast cancer potential of the microbial polyketide 2, 4-diacetylphloroglucinol (DAPG) and its interaction with the metastatic proteins than the antiapoptotic Bcl-2 proteins.
    Molecular and cellular biochemistry, 2016, Volume: 414, Issue:1-2

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Humans; Leukemia; Lung Neoplasms; Molecul

2016
Induction of apoptosis by phloroglucinol derivative from Ecklonia Cava in MCF-7 human breast cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2009, Volume: 47, Issue:7

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Brea

2009
CK1epsilon is required for breast cancers dependent on beta-catenin activity.
    PloS one, 2010, Feb-01, Volume: 5, Issue:2

    Topics: Animals; beta Catenin; Breast Neoplasms; Casein Kinase 1 epsilon; Cell Line; Cell Line, Tumor; Cell

2010
Dryofragin, a phloroglucinol derivative, induces apoptosis in human breast cancer MCF-7 cells through ROS-mediated mitochondrial pathway.
    Chemico-biological interactions, 2012, Aug-30, Volume: 199, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast; Breast Neoplasms; Cell Line, Tumor; Dryopteris

2012
Phosphorylation of nm23-H1 by CKI induces its complex formation with h-prune and promotes cell motility.
    Oncogene, 2008, Mar-20, Volume: 27, Issue:13

    Topics: Animals; Binding, Competitive; Breast Neoplasms; Caenorhabditis elegans; Carrier Proteins; Cell Comm

2008