phloroglucinol has been researched along with Brain Neoplasms in 5 studies
Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioblastoma is the most common primary brain tumor with poor survival rate and without effective treatment strategy." | 5.56 | Hyperforin induces apoptosis through extrinsic/intrinsic pathways and inhibits EGFR/ERK/NF-κB-mediated anti-apoptotic potential in glioblastoma. ( Chen, WT; Chung, JG; Hsu, FT; Wu, CT, 2020) |
| "This review focuses on a carotenoid and a phlorotannin present in seaweed, namely fucoxanthin and phloroglucinol, and their anticancer activity against glioblastoma." | 4.98 | Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review. ( Almeida, T; Azqueta, A; Ferreira, J; Ramos, AA; Rocha, E, 2018) |
| " John's wort (SJW) extract] modulates VEGF expression, possible relationship between≤μM hyperforin (Hyp, the bioactive component in SJW) and VEGF in CNS tumours has been now examined in medulloblastoma and glioblastoma cells." | 3.77 | Antidepressant hyperforin up-regulates VEGF in CNS tumour cells. ( Bradaschia, A; Garbisa, S; Maran, C; Masola, V; Onisto, M; Tassone, E, 2011) |
| "Glioma is the foremost recurrent type of brain tumor in humans; in particular, glioblastoma (GBM) is the main form of brain tumor (GBM) that is highly proliferative and impervious to apoptosis." | 1.72 | Triphlorethol-A attenuates U251 human glioma cancer cell proliferation and ameliorates apoptosis through JAK2/STAT3 and p38 MAPK/ERK signaling pathways. ( Ganesan, S; Jiang, B; Li, W; Su, Z; Wu, A; Yang, Z; Yuan, Z, 2022) |
| "Glioblastoma is the most common primary brain tumor with poor survival rate and without effective treatment strategy." | 1.56 | Hyperforin induces apoptosis through extrinsic/intrinsic pathways and inhibits EGFR/ERK/NF-κB-mediated anti-apoptotic potential in glioblastoma. ( Chen, WT; Chung, JG; Hsu, FT; Wu, CT, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 2 (40.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yuan, Z | 1 |
| Yang, Z | 1 |
| Li, W | 1 |
| Wu, A | 1 |
| Su, Z | 1 |
| Jiang, B | 1 |
| Ganesan, S | 1 |
| Hsu, FT | 1 |
| Chen, WT | 1 |
| Wu, CT | 1 |
| Chung, JG | 1 |
| Ferreira, J | 1 |
| Ramos, AA | 1 |
| Almeida, T | 1 |
| Azqueta, A | 1 |
| Rocha, E | 1 |
| Tassone, E | 1 |
| Maran, C | 1 |
| Masola, V | 1 |
| Bradaschia, A | 1 |
| Garbisa, S | 1 |
| Onisto, M | 1 |
| Prenner, L | 1 |
| Sieben, A | 1 |
| Zeller, K | 1 |
| Weiser, D | 1 |
| Häberlein, H | 1 |
1 review available for phloroglucinol and Brain Neoplasms
| Article | Year |
|---|---|
Drug resistance in glioblastoma and cytotoxicity of seaweed compounds, alone and in combination with anticancer drugs: A mini review.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplas | 2018 |
4 other studies available for phloroglucinol and Brain Neoplasms
| Article | Year |
|---|---|
Triphlorethol-A attenuates U251 human glioma cancer cell proliferation and ameliorates apoptosis through JAK2/STAT3 and p38 MAPK/ERK signaling pathways.
Topics: Antioxidants; Apoptosis; bcl-2-Associated X Protein; Brain Neoplasms; Caspases; Cell Line, Tumor; Ce | 2022 |
Hyperforin induces apoptosis through extrinsic/intrinsic pathways and inhibits EGFR/ERK/NF-κB-mediated anti-apoptotic potential in glioblastoma.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell L | 2020 |
Antidepressant hyperforin up-regulates VEGF in CNS tumour cells.
Topics: Antidepressive Agents; Apoptosis; Brain Neoplasms; Bridged Bicyclo Compounds; Cell Line, Tumor; Cell | 2011 |
Reduction of high-affinity beta2-adrenergic receptor binding by hyperforin and hyperoside on rat C6 glioblastoma cells measured by fluorescence correlation spectroscopy.
Topics: Animals; Brain Neoplasms; Bridged Bicyclo Compounds; Cell Line, Tumor; Cyclic AMP; Glioblastoma; Hum | 2007 |