phloroglucinol has been researched along with B-Cell Chronic Lymphocytic Leukemia in 7 studies
Phloroglucinol: A trinitrobenzene derivative with antispasmodic properties that is used primarily as a laboratory reagent.
phloroglucinol : A benzenetriol with hydroxy groups at position 1, 3 and 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of the hyperforin (HF), a natural phloroglucinol purified from Hypericum perforatum, were investigated ex vivo on leukemic cells from patients with B-cell chronic lymphocytic leukemia (B-CLL)." | 7.73 | Pro-apoptotic properties of hyperforin in leukemic cells from patients with B-cell chronic lymphocytic leukemia. ( Billard, C; Ensaf, A; Faussat, AM; Fourneron, JD; Kolb, JP; Naït-Si, Y; Quiney, C; Salanoubat, C, 2006) |
| "The effects of the hyperforin (HF), a natural phloroglucinol purified from Hypericum perforatum, were investigated ex vivo on leukemic cells from patients with B-cell chronic lymphocytic leukemia (B-CLL)." | 3.73 | Pro-apoptotic properties of hyperforin in leukemic cells from patients with B-cell chronic lymphocytic leukemia. ( Billard, C; Ensaf, A; Faussat, AM; Fourneron, JD; Kolb, JP; Naït-Si, Y; Quiney, C; Salanoubat, C, 2006) |
| "Hyperforin is a prenylated phloroglucinol present in the medicinal plant St John's wort (Hypericum perforatum)." | 2.49 | Mechanistic insights into the antileukemic activity of hyperforin. ( Bauvois, B; Billard, C; Merhi, F, 2013) |
| "Deficiency of apoptosis is a hallmark of chronic lymphocytic leukemia (CLL) cells." | 1.37 | The BH3-only protein Noxa is stimulated during apoptosis of chronic lymphocytic leukemia cells triggered by M2YN, a new plant-derived extract. ( Billard, C; Bombarda, I; Marie, JP; Mirshahi, M; Nuraliev, Y; Sharofova, M; Zaher, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaher, M | 3 |
| Akrout, I | 1 |
| Mirshahi, M | 2 |
| Kolb, JP | 3 |
| Billard, C | 6 |
| Nuraliev, Y | 1 |
| Sharofova, M | 1 |
| Bombarda, I | 2 |
| Marie, JP | 1 |
| Tang, R | 1 |
| Merhi, F | 2 |
| Bauvois, B | 2 |
| Quiney, C | 2 |
| Faussat, AM | 2 |
| Salanoubat, C | 2 |
| Ensaf, A | 1 |
| Naït-Si, Y | 1 |
| Fourneron, JD | 1 |
| Rund, D | 1 |
1 review available for phloroglucinol and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Mechanistic insights into the antileukemic activity of hyperforin.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B | 2013 |
6 other studies available for phloroglucinol and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
Noxa upregulation is associated with apoptosis of chronic lymphocytic leukemia cells induced by hyperforin but not flavopiridol.
Topics: Antibodies, Monoclonal; Apoptosis; Bridged Bicyclo Compounds; Flavonoids; Humans; Leukemia, Lymphocy | 2009 |
The BH3-only protein Noxa is stimulated during apoptosis of chronic lymphocytic leukemia cells triggered by M2YN, a new plant-derived extract.
Topics: Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; Caspase 3; DNA | 2011 |
Hyperforin induces apoptosis of chronic lymphocytic leukemia cells through upregulation of the BH3-only protein Noxa.
Topics: Aged; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Female; Gene Silencing; Humans; Leukemi | 2012 |
Pro-apoptotic properties of hyperforin in leukemic cells from patients with B-cell chronic lymphocytic leukemia.
Topics: Apoptosis; Blotting, Western; Bridged Bicyclo Compounds; Caspases; Cyclin-Dependent Kinase Inhibitor | 2006 |
Hyperforin modulation of drug resistance: saint or sinner?
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily | 2007 |
Hyperforin inhibits P-gp and BCRP activities in chronic lymphocytic leukaemia cells and myeloid cells.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transp | 2007 |