phlorhizin has been researched along with Diabetes Mellitus in 30 studies
*Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (43.33) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 4 (13.33) | 29.6817 |
| 2010's | 5 (16.67) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Beier, N; Burckhardt, BC; Burckhardt, G; Gorboulev, V; Koepsell, H; Kottra, G; Palm, D; Pipkorn, R; van Amsterdam, C; Vernaleken, A; Veyhl, M | 1 |
| Demarest, K; Du, F; Gaul, MD; Kuo, GH; Liang, Y; Xu, G; Xu, JZ | 1 |
| Anan, G; Endo, A; Hashimoto, H; Hirose, T; Ishiyama, K; Ito, H; Kikuchi, D; Kimura, T; Mori, T; Nakayama, S; Sato, M; Sato, S; Takahashi, C; Takahashi, K | 1 |
| Miyamoto, L; Tsuchiya, K | 1 |
| GINGRAS, R; PAGE, E | 1 |
| Ehrenkranz, J | 1 |
| Hawkins, WB; Hawley, GM; Kummer, AJ; McKee, FW | 1 |
| Castaneda, F; Kinne, RK | 1 |
| Barrio, JR; Ghezzi, C; Hirayama, BA; Hummel, CS; Kepe, V; Liu, J; Loo, DD; Lu, C; Wright, EM | 1 |
| Abcouwer, SF; Barber, AJ; Fort, PE; Gardner, TW; Losiewicz, MK; Nakamura, M; Reiter, CE; Singh, RS | 1 |
| Cai, Q; Gao, HQ; Li, BY; Lu, WD; Yin, M; Yu, F; Zhang, Z | 1 |
| Hermus, AR; Janssen, SW; Martens, GJ; Span, PN; Sweep, CG; Verhofstad, AA | 1 |
| HIERONYMI, G | 1 |
| D'Agord Schaan, B; da Silva, RS; Freitas, HS; Machado, UF; Okamoto, MM; Oliveira-Souza, M | 1 |
| BARTLETT, PD; GAEBLER, OH | 1 |
| Bilinski, D; El Tayeb, K; Gauthier, C; Hetenyi, G; Lickley, HL; Vranic, M; Wasserman, D | 1 |
| Efendic, S; Khan, A | 1 |
| Mizuno, A; Noma, Y; Sano, T; Shima, K; Zhu, M | 1 |
| Kuwajima, M; Murakami, T; Ogino, T; Shima, K; Zhu, M | 1 |
| Fujimiya, M; Fujita, Y; Hidaka, H; Kashiwagi, A; Kikkawa, R; Kojima, H | 1 |
| Efendic, S; Henningsson, R; Lundquist, I; Mosén, H; Ostenson, CG; Salehi, A | 1 |
| Valverde, I; Villanueva, ML | 1 |
| Förster, H | 1 |
| Baumer, G; Dirksen, G; Giesecke, VD; Günzel, R | 1 |
| Dimitrakoudis, D; Klip, A; Vranic, M | 1 |
| Giesecke, D; Günzel, R | 1 |
| Berger, M; Goodman, MN; Ross, PS; Ruderman, NB | 1 |
| Lesse, H | 1 |
| Filsell, OH; Jarrett, IG; Keech, DB; Taylor, PH | 1 |
| Hellman, B; Lernmark, A; Sehlin, J; Täljedal, IB | 1 |
3 review(s) available for phlorhizin and Diabetes Mellitus
| Article | Year |
|---|---|
[Sodium-Glucose Transporters as a Therapeutic Target for Diabetes from the Viewpoint of Drug Discovery and Pharmacotherapy].
Topics: Body Weight; Carbonates; Diabetes Mellitus; Drug Discovery; Energy Metabolism; Glucosides; Humans; Hypoglycemic Agents; Molecular Targeted Therapy; Phloretin; Phlorhizin; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors | 2018 |
SGLT inhibitors as new therapeutic tools in the treatment of diabetes.
Topics: Animals; Diabetes Mellitus; Humans; Hypoglycemic Agents; Phlorhizin; Sodium-Glucose Transport Proteins; Structure-Activity Relationship | 2011 |
Effects of hyperglycemia on glucose transporters of the muscle: use of the renal glucose reabsorption inhibitor phlorizin to control glycemia.
Topics: Animals; Binding, Competitive; Blood Glucose; Cytochalasin B; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glucose Transporter Type 4; Glycosylation; Humans; Hyperglycemia; Insulin; Insulin Resistance; Intestinal Absorption; Kidney Tubules, Proximal; Monosaccharide Transport Proteins; Multigene Family; Muscle Proteins; Muscles; Organ Specificity; Phlorhizin; Rats; Subcellular Fractions | 1992 |
27 other study(ies) available for phlorhizin and Diabetes Mellitus
| Article | Year |
|---|---|
Tripeptides of RS1 (RSC1A1) inhibit a monosaccharide-dependent exocytotic pathway of Na+-D-glucose cotransporter SGLT1 with high affinity.
Topics: Animals; Antimetabolites; Biological Transport, Active; Caco-2 Cells; Deoxyglucose; Diabetes Mellitus; Female; Gastrointestinal Motility; Gene Expression; Glucose; Humans; Intestinal Absorption; Liver; Male; Methylglucosides; Monosaccharide Transport Proteins; Oligopeptides; Oocytes; Peptide Transporter 1; Protein Processing, Post-Translational; Rats; Rats, Wistar; Sodium-Glucose Transporter 1; Symporters; trans-Golgi Network; Xenopus laevis | 2007 |
5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Drug Design; Glucose Tolerance Test; Glucosides; Half-Life; Halogenation; Humans; Hypoglycemic Agents; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Microsomes; Rats; Rats, Sprague-Dawley; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Structure-Activity Relationship | 2020 |
Inhibition of sodium-glucose cotransporter 2 suppresses renal stone formation.
Topics: Animals; Calcium Oxalate; Diabetes Mellitus; Glucose; Humans; Inflammation; Kidney Calculi; Male; Mice; Phlorhizin; Rats; Rats, Sprague-Dawley; Sodium; Sodium-Glucose Transporter 2 Inhibitors | 2022 |
Glycosuria in phlorizinized rats depleted of pyridoxine.
Topics: Animals; Diabetes Mellitus; Glycosuria; Phlorhizin; Pyridoxine; Rats; Vitamin B 6 Deficiency | 1948 |
Glucose control, the kidney, and potential treatments for diabetes: more to the story.
Topics: Blood Glucose; Diabetes Mellitus; Humans; Kidney; Phlorhizin | 2009 |
THE METABOLISM OF AMINO ACIDS AND CASEIN DIGEST IN PHLORHIZINIZED DOGS.
Topics: Amino Acids; Animals; Caseins; Diabetes Mellitus; Dogs; Nitrogen; Phlorhizin | 1947 |
Structural selectivity of human SGLT inhibitors.
Topics: Benzhydryl Compounds; Biological Transport; Diabetes Mellitus; Glucose; Glucosides; HEK293 Cells; Humans; Kidney; Molecular Structure; Patch-Clamp Techniques; Phlorhizin; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Substrate Specificity | 2012 |
Differential roles of hyperglycemia and hypoinsulinemia in diabetes induced retinal cell death: evidence for retinal insulin resistance.
Topics: Animals; Cell Death; Diabetes Mellitus; Diabetic Retinopathy; Hyperglycemia; Insulin; Insulin Resistance; Phlorhizin; Rats; Retina; Signal Transduction | 2011 |
Quantitative proteomics study on the protective mechanism of phlorizin on hepatic damage in diabetic db/db mice.
Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus; Gene Expression Regulation; Lipid Metabolism; Liver; Mice; Mice, Mutant Strains; Phlorhizin; Proteomics | 2012 |
Phlorizin treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker diabetic fatty rats.
Topics: Aging; Amyloid; Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Insulin; Islet Amyloid Polypeptide; Islets of Langerhans; Male; Monosaccharide Transport Proteins; Obesity; Phlorhizin; Proteins; Rats; Rats, Zucker; RNA, Messenger | 2003 |
[Phlorhizin diabetes and alkaline phosphatase].
Topics: Alkaline Phosphatase; Diabetes Mellitus; Humans; Phlorhizin; Phosphoric Monoester Hydrolases | 1950 |
Insulin but not phlorizin treatment induces a transient increase in GLUT2 gene expression in the kidney of diabetic rats.
Topics: Animals; Diabetes Mellitus; Gene Expression; Glucose Transporter Type 2; Hypoglycemic Agents; Insulin; Kidney; Male; Phlorhizin; Rats; Rats, Wistar | 2007 |
Phlorhizin diabetes in vitamin deficiencies; conversion of protein to glucose, and serum phosphatase, during deficiencies of thiamine, riboflavin, and pyridoxine.
Topics: Avitaminosis; Deficiency Diseases; Diabetes Mellitus; Glucose; Humans; Phlorhizin; Phosphoric Monoester Hydrolases; Pyridoxine; Riboflavin; Thiamine | 1949 |
Catecholamine responses and their interactions with other glucoregulatory hormones.
Topics: Adolescent; Adult; Animals; Blood Glucose; Diabetes Mellitus; Dogs; Epinephrine; Glucagon; Humans; Hypoglycemia; Insulin; Kinetics; Metabolic Clearance Rate; Pancreatectomy; Phlorhizin; Physical Exertion; Somatostatin | 1984 |
Evidence that increased glucose cycling in islets of diabetic ob/ob mice is a primary feature of the disease.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Glucose; Insulin; Islets of Langerhans; Mice; Mice, Mutant Strains; Osmolar Concentration; Phlorhizin | 1995 |
Poor capacity for proliferation of pancreatic beta-cells in Otsuka-Long-Evans-Tokushima Fatty rat: a model of spontaneous NIDDM.
Topics: Animals; Blood Glucose; Body Weight; Cell Division; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Islets of Langerhans; Male; Niacinamide; Obesity; Pancreatectomy; Phlorhizin; Rats; Rats, Mutant Strains | 1996 |
Effect of partial pancreatectomy on beta-cell mass in the remnant pancreas of Wistar fatty rats.
Topics: Animals; Blood Glucose; Cell Division; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Genotype; Hyperglycemia; Insulin; Insulin Resistance; Islets of Langerhans; Male; Niacinamide; Obesity; Pancreatectomy; Phenotype; Phlorhizin; Rats; Rats, Inbred WKY; Rats, Mutant Strains; Rats, Wistar; Rats, Zucker | 1998 |
Increased intestinal glucose absorption and postprandial hyperglycaemia at the early step of glucose intolerance in Otsuka Long-Evans Tokushima Fatty rats.
Topics: Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Food; Gene Expression; Glucose; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Insulin Resistance; Intestinal Absorption; Intestines; Male; Monosaccharide Transport Proteins; Obesity; Phlorhizin; Rats; Rats, Long-Evans; Xylose | 1998 |
Dysfunction of the islet lysosomal system conveys impairment of glucose-induced insulin release in the diabetic GK rat.
Topics: Acarbose; Animals; Colforsin; Diabetes Mellitus; Enzyme Inhibitors; Glucan 1,4-alpha-Glucosidase; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Liver; Lysosomes; Phlorhizin; Rats; Rats, Inbred Strains; Rats, Wistar; Trisaccharides | 1999 |
Heterogeneity of plasma immunoreactive glucagon.
Topics: Animals; Diabetes Mellitus; Dogs; Ducks; Glucagon; Humans; Hypoglycemia; Immunoglobulin G; Kidney; Kidney Failure, Chronic; Liver Cirrhosis; Mice; Molecular Weight; Phlorhizin | 1976 |
Metabolism of glucose substitutes compared to that of glucose.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Fatty Acids, Nonesterified; Fructose; Glucose; Lactates; Liver; Liver Glycogen; Perfusion; Phlorhizin; Rats; Sorbitol; Urea; Xylitol | 1976 |
[Glucogenic effect of 1,2-propandiol in healthy cows and in sheep with phlorhizin diabetes].
Topics: Animals; Blood Glucose; Cattle; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Gluconeogenesis; Male; Phlorhizin; Propylene Glycols; Rumen; Sheep; Sheep Diseases | 1975 |
[Effect of feeding, fasting and phlorhizin diabetes on the relationship between free fatty acids and glucose in sheep blood].
Topics: Animal Nutritional Physiological Phenomena; Animals; Blood Glucose; Diabetes Mellitus; Disease Models, Animal; Fasting; Fatty Acids; Male; Phlorhizin; Sheep | 1974 |
Regulation of glucose and ketone-body metabolism in brain of anaesthetized rats.
Topics: Acetoacetates; Acetyl Coenzyme A; Adenine Nucleotides; Animals; Biological Transport; Blood Glucose; Blood-Brain Barrier; Brain; Citrates; Diabetes Mellitus; Female; Glucose; Glycogen; Hydroxybutyrates; Ketone Bodies; Lactates; Pentobarbital; Phlorhizin; Phosphocreatine; Rats; Spectrometry, Fluorescence; Starvation; Streptozocin; Time Factors | 1974 |
Glucose accumulation by rat small intestine during absorption in vivo.
Topics: Animals; Biological Transport, Active; Blood Glucose; Diabetes Mellitus; Glucose; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Jejunum; Male; Phlorhizin; Rats; Streptozocin | 1974 |
Effects of fasting, diabetes and glucocorticoids on gluconeogenic enzymes in the sheep.
Topics: Aldehyde-Lyases; Animals; Blood Glucose; Carboxy-Lyases; Cortisone; Dexamethasone; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fasting; Female; Gluconeogenesis; Glucose-6-Phosphatase; Ketone Bodies; Kidney; Ligases; Liver; Pancreas; Pancreatectomy; Phlorhizin; Pregnancy; Rats; Sheep; Species Specificity | 1969 |
The pancreatic -cell recognition of insulin secretagogues. V. Binding and stimulatory action of phlorizin.
Topics: Animals; Antimycin A; Arginine; Carbon Isotopes; Chloromercuribenzoates; Chlorpromazine; Diabetes Mellitus; Dose-Response Relationship, Drug; Glucose; Heptoses; Hyperglycemia; Insulin; Insulin Secretion; Iodine Isotopes; Islets of Langerhans; Ketones; Mice; Obesity; Organ Size; Phloretin; Phlorhizin; Sucrose; Theophylline; Time Factors; Tritium | 1972 |