phloretin has been researched along with Parkinson Disease in 1 studies
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phloretin (PLT) is a phenolic compound reported possessing anti-inflammatory and antioxidant activities." | 1.91 | Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk. ( Khatri, DK; Kumar, R; Preeti, K; Shirgadwar, SM; Singh, SB, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shirgadwar, SM | 3 |
| Kumar, R | 3 |
| Preeti, K | 3 |
| Khatri, DK | 3 |
| Singh, SB | 3 |
1 other study available for phloretin and Parkinson Disease
| Article | Year |
|---|---|
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5 | 2023 |
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5 | 2023 |
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5 | 2023 |
Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson's Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk.
Topics: Animals; Antioxidants; Autophagy; Humans; Kelch-Like ECH-Associated Protein 1; Mice; Mice, Inbred C5 | 2023 |