phloretin has been researched along with Diabetes Mellitus, Type 2 in 7 studies
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The rising prevalence of type 2 diabetes mellitus (T2DM) and accompanying insulin resistance is alarming globally." | 5.91 | Phloretin and phlorizin mitigates inflammatory stress and alleviate adipose and hepatic insulin resistance by abrogating PPARγ S273-Cdk5 interaction in type 2 diabetic mice. ( Chhimwal, J; Kumar, S; Padwad, YS; Patial, V; Purohit, R; Singh, R, 2023) |
| "The rising prevalence of type 2 diabetes mellitus (T2DM) and accompanying insulin resistance is alarming globally." | 1.91 | Phloretin and phlorizin mitigates inflammatory stress and alleviate adipose and hepatic insulin resistance by abrogating PPARγ S273-Cdk5 interaction in type 2 diabetic mice. ( Chhimwal, J; Kumar, S; Padwad, YS; Patial, V; Purohit, R; Singh, R, 2023) |
| "Phloretin is a dihydrochalcone flavonoid from natural plants, which has protective activities against oxidative stress and inflammation." | 1.72 | Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect. ( Cui, X; Jiang, J; Liu, J; Sun, M; Xia, Y, 2022) |
| "Type 2 diabetes mellitus is characterized by impaired glucose uptake." | 1.31 | The abnormality of glucose transporter in the erythrocyte membrane of Chinese type 2 diabetic patients. ( Cheng, WY; Feng, HF; Hu, XJ; Peng, F; Zhang, ZH; Zhou, HQ, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Jesus, AR | 1 |
| Vila-Viçosa, D | 1 |
| Machuqueiro, M | 1 |
| Marques, AP | 1 |
| Dore, TM | 1 |
| Rauter, AP | 1 |
| Liu, J | 1 |
| Sun, M | 1 |
| Xia, Y | 1 |
| Cui, X | 1 |
| Jiang, J | 1 |
| Kumar, S | 2 |
| Chhimwal, J | 1 |
| Singh, R | 1 |
| Patial, V | 1 |
| Purohit, R | 1 |
| Padwad, YS | 1 |
| Londzin, P | 1 |
| Siudak, S | 1 |
| Cegieła, U | 1 |
| Pytlik, M | 1 |
| Janas, A | 1 |
| Waligóra, A | 1 |
| Folwarczna, J | 1 |
| Luiken, JJ | 1 |
| Koonen, DP | 1 |
| Willems, J | 1 |
| Zorzano, A | 1 |
| Becker, C | 1 |
| Fischer, Y | 1 |
| Tandon, NN | 1 |
| Van Der Vusse, GJ | 1 |
| Bonen, A | 1 |
| Glatz, JF | 1 |
| Feneberg, R | 1 |
| Lemmer, B | 1 |
| Hu, XJ | 1 |
| Peng, F | 1 |
| Zhou, HQ | 1 |
| Zhang, ZH | 1 |
| Cheng, WY | 1 |
| Feng, HF | 1 |
7 other studies available for phloretin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Targeting Type 2 Diabetes with C-Glucosyl Dihydrochalcones as Selective Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitors: Synthesis and Biological Evaluation.
Topics: Chalcones; Diabetes Mellitus, Type 2; Glucosides; HEK293 Cells; Humans; Membranes, Artificial; Molec | 2017 |
Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Intrace | 2022 |
Phloretin and phlorizin mitigates inflammatory stress and alleviate adipose and hepatic insulin resistance by abrogating PPARγ S273-Cdk5 interaction in type 2 diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin Resistance; Mice; Obesi | 2023 |
Phloridzin, an Apple Polyphenol, Exerted Unfavorable Effects on Bone and Muscle in an Experimental Model of Type 2 Diabetes in Rats.
Topics: Animals; Bone and Bones; Bone Density; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; D | 2018 |
Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36.
Topics: Androstadienes; Animals; Biological Transport; CD36 Antigens; Deoxyglucose; Diabetes Mellitus, Type | 2002 |
Circadian rhythm of glucose uptake in cultures of skeletal muscle cells and adipocytes in Wistar-Kyoto, Wistar, Goto-Kakizaki, and spontaneously hypertensive rats.
Topics: Adipocytes; Animals; Biological Transport, Active; Cells, Cultured; Circadian Rhythm; Deoxyglucose; | 2004 |
The abnormality of glucose transporter in the erythrocyte membrane of Chinese type 2 diabetic patients.
Topics: Asian People; China; Cytochalasin B; Diabetes Mellitus, Type 2; Energy Metabolism; Erythrocyte Membr | 2000 |