phloretin has been researched along with Alloxan Diabetes in 17 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In starvation, glycerol is released from adipose tissue and serves as an important precursor for hepatic gluconeogenesis." | 7.78 | Estrogen prevents increased hepatic aquaporin-9 expression and glycerol uptake during starvation. ( Calamita, G; Gena, P; Lebeck, J; Lund, S; O'Neill, H; Praetorius, J; Skowronski, MT, 2012) |
| "The rising prevalence of type 2 diabetes mellitus (T2DM) and accompanying insulin resistance is alarming globally." | 5.91 | Phloretin and phlorizin mitigates inflammatory stress and alleviate adipose and hepatic insulin resistance by abrogating PPARγ S273-Cdk5 interaction in type 2 diabetic mice. ( Chhimwal, J; Kumar, S; Padwad, YS; Patial, V; Purohit, R; Singh, R, 2023) |
| "In starvation, glycerol is released from adipose tissue and serves as an important precursor for hepatic gluconeogenesis." | 3.78 | Estrogen prevents increased hepatic aquaporin-9 expression and glycerol uptake during starvation. ( Calamita, G; Gena, P; Lebeck, J; Lund, S; O'Neill, H; Praetorius, J; Skowronski, MT, 2012) |
| "The rising prevalence of type 2 diabetes mellitus (T2DM) and accompanying insulin resistance is alarming globally." | 1.91 | Phloretin and phlorizin mitigates inflammatory stress and alleviate adipose and hepatic insulin resistance by abrogating PPARγ S273-Cdk5 interaction in type 2 diabetic mice. ( Chhimwal, J; Kumar, S; Padwad, YS; Patial, V; Purohit, R; Singh, R, 2023) |
| "Phloretin is a dihydrochalcone flavonoid from natural plants, which has protective activities against oxidative stress and inflammation." | 1.72 | Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect. ( Cui, X; Jiang, J; Liu, J; Sun, M; Xia, Y, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (29.41) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 5 (29.41) | 2.80 |
| Authors | Studies |
|---|---|
| Mao, W | 1 |
| Fan, Y | 1 |
| Wang, X | 2 |
| Feng, G | 1 |
| You, Y | 1 |
| Li, H | 1 |
| Chen, Y | 1 |
| Yang, J | 1 |
| Weng, H | 1 |
| Shen, X | 3 |
| Liu, J | 1 |
| Sun, M | 1 |
| Xia, Y | 1 |
| Cui, X | 1 |
| Jiang, J | 1 |
| Kumar, S | 2 |
| Chhimwal, J | 1 |
| Singh, R | 1 |
| Patial, V | 1 |
| Purohit, R | 1 |
| Padwad, YS | 1 |
| Shelke, V | 1 |
| Kale, A | 1 |
| Dagar, N | 1 |
| Habshi, T | 1 |
| Gaikwad, AB | 1 |
| Wang, L | 2 |
| Zhou, N | 2 |
| Gai, S | 1 |
| Liu, X | 2 |
| Zhang, S | 2 |
| Balaha, M | 1 |
| Kandeel, S | 1 |
| Kabel, A | 1 |
| Londzin, P | 1 |
| Siudak, S | 1 |
| Cegieła, U | 1 |
| Pytlik, M | 1 |
| Janas, A | 1 |
| Waligóra, A | 1 |
| Folwarczna, J | 1 |
| Ying, Y | 1 |
| Jiang, C | 1 |
| Zhang, M | 1 |
| Jin, J | 1 |
| Ge, S | 1 |
| Jaber, H | 1 |
| Baydoun, E | 1 |
| EL-Zein, O | 1 |
| Kreydiyyeh, SI | 1 |
| Sampath, C | 1 |
| Sang, S | 1 |
| Ahmedna, M | 1 |
| Mi, L | 1 |
| Hu, Z | 1 |
| Lebeck, J | 1 |
| Gena, P | 1 |
| O'Neill, H | 1 |
| Skowronski, MT | 1 |
| Lund, S | 1 |
| Calamita, G | 1 |
| Praetorius, J | 1 |
| Csáky, TZ | 1 |
| Fischer, E | 1 |
| Ennis, SR | 1 |
| Johnson, JE | 1 |
| Pautler, EL | 1 |
| Dunlop, ME | 1 |
| Hill, MA | 1 |
| Larkins, RG | 1 |
| Ullrich, KJ | 1 |
| Papavassiliou, F | 1 |
| Bailey, LE | 1 |
| Dresel, PE | 1 |
17 other studies available for phloretin and Alloxan Diabetes
| Article | Year |
|---|---|
Phloretin ameliorates diabetes-induced endothelial injury through AMPK-dependent anti-EndMT pathway.
Topics: AMP-Activated Protein Kinases; Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Human Umbi | 2022 |
Phloretin ameliorates diabetic nephropathy by inhibiting nephrin and podocin reduction through a non-hypoglycemic effect.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Intrace | 2022 |
Phloretin and phlorizin mitigates inflammatory stress and alleviate adipose and hepatic insulin resistance by abrogating PPARγ S273-Cdk5 interaction in type 2 diabetic mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Insulin Resistance; Mice; Obesi | 2023 |
Concomitant inhibition of TLR-4 and SGLT2 by phloretin and empagliflozin prevents diabetes-associated ischemic acute kidney injury.
Topics: Acute Kidney Injury; Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Ischemia; Mal | 2023 |
Beneficial effects of combination therapy of phloretin and metformin in streptozotocin-induced diabetic rats and improved insulin sensitivity in vitro.
Topics: Adipose Tissue; Animals; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; Insulin Recept | 2020 |
Phloretin either alone or in combination with duloxetine alleviates the STZ-induced diabetic neuropathy in rats.
Topics: Animals; Behavior, Animal; Blood Glucose; Capillaries; Cold Temperature; Cytokines; Diabetes Mellitu | 2018 |
Phloridzin, an Apple Polyphenol, Exerted Unfavorable Effects on Bone and Muscle in an Experimental Model of Type 2 Diabetes in Rats.
Topics: Animals; Bone and Bones; Bone Density; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; D | 2018 |
Phloretin protects against cardiac damage and remodeling via restoring SIRT1 and anti-inflammatory effects in the streptozotocin-induced diabetic mouse model.
Topics: Animals; Cell Line; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Fibrosis; Gene Expre | 2019 |
Anti-hyperglycemic effect of the aqueous extract of banana infructescence stalks in streptozotocin-induced diabetic rats.
Topics: Animals; Biological Transport; Blood Glucose; Caco-2 Cells; Colon; Diabetes Mellitus, Experimental; | 2013 |
In vitro and in vivo inhibition of aldose reductase and advanced glycation end products by phloretin, epigallocatechin 3-gallate and [6]-gingerol.
Topics: Aldehyde Reductase; Animals; Biomarkers; Blood Glucose; Catechin; Catechols; Cell Line; Cell Surviva | 2016 |
Phloretin exerts hypoglycemic effect in streptozotocin-induced diabetic rats and improves insulin resistance in vitro.
Topics: Animals; Blood Glucose; Cell Survival; Cells, Cultured; Diabetes Mellitus, Experimental; Glucose; Gl | 2017 |
Estrogen prevents increased hepatic aquaporin-9 expression and glycerol uptake during starvation.
Topics: Animals; Aquaporins; Blood Glucose; Cell Membrane; Diabetes Mellitus, Experimental; Estradiol; Estro | 2012 |
Intestinal sugar transport in experimental diabetes.
Topics: 3-O-Methylglucose; Animals; Blood Glucose; Cycloheximide; Diabetes Mellitus, Experimental; Galactose | 1981 |
In situ kinetics of glucose transport across the blood-retinal barrier in normal rats and rats with streptozocin-induced diabetes.
Topics: Acetazolamide; Animals; Biological Transport; Diabetes Mellitus, Experimental; Electroretinography; | 1982 |
The influence of insulin and sorbinil on myoinositol uptake in peripheral nerve from normal and diabetic rats and a neuroblastoma cell line (N1E-115).
Topics: Aldehyde Reductase; Animals; Cell Line; Diabetes Mellitus, Experimental; Femoral Nerve; Glucose; Imi | 1988 |
Contraluminal transport of hexoses in the proximal convolution of the rat kidney in situ.
Topics: Animals; Biological Transport; Chlormerodrin; Deoxyglucose; Diabetes Mellitus, Experimental; Hexoses | 1985 |
Role of the sugar transport system in the positive inotropic response to digitalis.
Topics: Animals; Biological Transport; Carbohydrates; Cardanolides; Diabetes Mellitus, Experimental; Electri | 1971 |