pheophorbide-a and Skin-Diseases

pheophorbide-a has been researched along with Skin-Diseases* in 1 studies

Other Studies

1 other study(ies) available for pheophorbide-a and Skin-Diseases

Article	Year
Pheophorbide A from Solanum diflorum interferes with NF-kappa B activation. Planta medica, 2001, Volume: 67, Issue:2 Continuing our search for biogenic NF-kappa B inhibitors we investigated Solanum diflorum, used by the Istmo Sierra Zapotec Indians of Mexico in the treatment of inflammatory skin conditions. It became obvious very early that the active substance seems to be a degradation product of chlorophyll. Pheophorbide A was identified as one of the key compounds responsible for the NF-kappa B inhibitory activity. The compound interferes with NF-kappa B activation, was cytotoxic if exposed to light, but devoid of any cytotoxic activity in the dark. Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorophyll; Darkness; HeLa Cells; Humans; Mexican Americans; NF-kappa B; Plant Extracts; Plant Leaves; Plants, Medicinal; Skin Diseases; Solanaceae	2001

Article

Year

Pheophorbide A from Solanum diflorum interferes with NF-kappa B activation.

Planta medica, 2001, Volume: 67, Issue:2

Continuing our search for biogenic NF-kappa B inhibitors we investigated Solanum diflorum, used by the Istmo Sierra Zapotec Indians of Mexico in the treatment of inflammatory skin conditions. It became obvious very early that the active substance seems to be a degradation product of chlorophyll. Pheophorbide A was identified as one of the key compounds responsible for the NF-kappa B inhibitory activity. The compound interferes with NF-kappa B activation, was cytotoxic if exposed to light, but devoid of any cytotoxic activity in the dark.

Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorophyll; Darkness; HeLa Cells; Humans; Mexican Americans; NF-kappa B; Plant Extracts; Plant Leaves; Plants, Medicinal; Skin Diseases; Solanaceae

2001